Clinical trials: Gastrointestinal Tumor Surgery
Hepatocellular Carcinoma
A Study to Evaluate Sintilimab Plus Lenvatinib as Adjuvant Therapy in Hepatocellular Carcinoma With Portal Vein Tumor Thrombosis (PVTT) After Surgical Resection
To compare the impact on recurrence risk of adjuvant Sintilimab (a recombinant fully human anti-PD-1 monoclonal antibody) plus Lenvatinib for patients with hepatocellular carcinoma and portal vein tumor thrombus (PVTT ) after…
- Trial name
- NCT06089382
- Testing
- Sintilimab, Lenvatinib, Transarterial Chemoembolization (TACE)
- Where
- China
- Volunteers
- 104 people
- Sponsor
- Tongji Hospital
Advanced Colorectal Cancer in Elderly Patient
The Management of Complicated Colo-rectal Cancer in Older Patients in the Emergency Setting: the CO-OLDER Study
This is a multicenter observational study aimed to investigate the management of older patients aged 75 years old and over admitted to the emergency department with complicated colorectal cancer.
- Trial name
- CO-OLDER (NCT05788224)
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Poissy-Saint Germain Hospital
Colorectal Cancer, Metastatic Cancer
Matrix Metalloproteinases After Surgery and/or Radiofrequency Ablation in Patients With Liver Metastases From Colorectal Cancer
RATIONALE: Studying samples of blood from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer.
- Trial name
- NCT00899210
- Testing
- laboratory biomarker analysis, cryosurgery, radiofrequency ablation
- Volunteers
- 75 people
- Sponsor
- University Hospital, Grenoble
Gastric Cancer
Laparoscopic Sentinel Node Navigation Surgery for Gastric Cancer
There are few reports on a dual dye and isotope approach using laparoscopy in gastric cancer sentinel node mapping. The aim of this study was to evaluate the feasibility of laparoscopic limited gastrectomy with sentinel basin(SB)…
- Trial name
- SNNS (NCT01441310)
- Testing
- Laparoscopic sentinel node navigation surgery
- Where
- South Korea
- Volunteers
- 101 people
- Sponsor
- Seoul National University Bundang Hospital
Metastatic Liver Cancer, Cholangiocarcinoma
Pilot Study of Irreversible Electroporation (IRE) to Treat Metastatic Liver Cancer & Cholangiocarcinoma
Single-arm pilot clinical trial. Patients will be subjected to irreversible electroporation (IRE) as the sole treatment of nodules not considered treatable by resection or thermal ablation.
- Conditions
- Metastatic Liver Cancer, Cholangiocarcinoma, Neoplasm Metastasis
- Trial name
- NCT01442324
- Testing
- Irreversible electroporation (IRE)
- Where
- Italy
- Volunteers
- 5 people
- Sponsor
- Azienda Ospedaliera di Padova
Immunity
Prospective Comparison of Immunological Benefit of Laparoscopic Colectomy
This study aimed to clarify existence of immunological benefit of laparoscopic colon cancer surgery compared to open colon surgery.
- Trial name
- NCT00744159
- Where
- South Korea
- Volunteers
- 84 people
- Sponsor
- Samsung Medical Center
Carcinoma Surgery, Parenteral Nutrition
The Impact of Omega-3 Fat Emulsion on Clinical Outcome of Post-Operative Cancer Patients
The purpose of this study is to evaluate clinical safety and effect of Omega-3 fat oil emulsion on outcome in post-operative cancer patients.
- Conditions
- Carcinoma Surgery, Parenteral Nutrition, Post-Operative Hospital Stay
- Trial name
- NCT00292279
- Testing
- Omega-3 fish oil emulsion (Omegaven ), long-chain triglyceride
- Where
- 5 sites in China
- Volunteers
- 206 people
- Sponsor
- Sino-Swed Pharmaceutical Corporation
Rectal Cancer
Timisnar - Biomarkers Substudy (Timisnar-mirna)
Neoadjuvant chemoradiotherapy (nCHT) followed by surgery is the mainstay treatment for locally advanced rectal cancer, leading to significant decrease in tumor size (downsizing) and a shift towards earlier disease stage in the…
- Trial name
- TiMiSNAR-miRNA (NCT03962088)
- Testing
- miRNA
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- Azienda Ospedaliera SS. Antonio e Biagio e Cesare Arrigo di Alessandria
Colorectal Cancer
Standard Versus Advanced Antimicrobial Dressing Containing Ionic Silver Following Colorectal Cancer Surgery
The purpose of this study is to evaluate the efficacy of treatment with hydrofibre dressing in comparison with the efficacy of standard dressing in terms of prevalence of surgical site infections (SSI) in patients who underwent…
- Trial name
- AM (NCT00981110)
- Testing
- AQUAGEL Ag Hydrofiber Wound Dressing, Mepore Self-adhesive absorbent dressing
- Where
- 2 sites in Italy
- Volunteers
- 120 people
- Sponsor
- European Institute of Oncology
Extrahepatic Bile Duct Cancer, Gallbladder Cancer
Fluorouracil, Cisplatin, and Radiation Therapy or Gemcitabine and Oxaliplatin in Treating Patients With Nonmetastatic Biliary Tract Cancer That Cannot Be Removed By Surgery
RATIONALE: Drugs used in chemotherapy, such as fluorouracil, cisplatin, oxaliplatin, and gemcitabine, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing.
- Conditions
- Extrahepatic Bile Duct Cancer, Gallbladder Cancer, Liver Cancer
- Trial name
- NCT00304135
- Testing
- cisplatin, gemcitabine hydrochloride, oxaliplatin
- Where
- 20 sites in France
- Volunteers
- 34 people
- Sponsor
- Federation Francophone de Cancerologie Digestive
Pancreatic Neuroendocrine Tumor, Pancreas Cancer
Preoperative PRRT Versus Surgical Cytoreduction in Metastatic Pancreatic Neuroendocrine Tumors to the Liver
Doctors and researchers leading this study hope to learn more about peptide receptor radionuclide therapy (PRRT) in combination with cytoreduction (surgically removing tumors).
- Trial name
- NCT05610826
- Testing
- cytoreductive surgery, Lutathera - a small molecule used in Peptide Receptor Radionuclide Therapy (PRRT), Peptide receptor radionuclide therapy (PRRT)
- Where
- United States
- Sponsor
- University of Chicago
Esophageal Cancer
Modular Robot-Assisted Versus Conventional Minimally Invasive Esophagectomy for Esophageal Cancer
This study evaluates the safety, efficacy, and health economic outcomes of modular robotic-assisted minimally invasive esophagectomy (RAMIE) compared with conventional thoracoscopic minimally invasive esophagectomy (MIE) in…
- Trial name
- mRAMIE2026 (NCT07888140)
- Testing
- Modular Robot-Assisted Esophagectomy, Conventional Minimally Invasive Esophagectomy
- Where
- China
- Volunteers
- 160 people
- Sponsor
- Ruijin Hospital
Hepatocellular Carcinoma (HCC)
HCC-MPDS Multimodal Deep Learning Prognostic Model for Resectable HCC
This is a completed multi-center retrospective observational study focusing on patients who received curative surgical resection for hepatocellular carcinoma (HCC).
- Trial name
- HCC-MPDS (NCT07700082)
- Where
- China
- Volunteers
- 555 people
- Sponsor
- Anhui Provincial Hospital
GIST of Stomach, Gastric Cancer
Comparison of Tumor Efficacy Safety in Laparoscopic Resection of Gastrointestinal Stromal Tumors Between Favorable and Unfavorable Site
Participants with gastrointestinal stromal tumors(GIST) were divided into favorable and unfavorable sites according to the anatomical site of the tumor, and this study aims to validate the overall postoperative morbidity and…
- Conditions
- GIST of Stomach, Gastric Cancer, Surgery, Complication
- Trial name
- NCT03716089
- Testing
- Laparoscopic resection
- Where
- China
- Volunteers
- 250 people
- Sponsor
- Fujian Medical University
Gastric Cancer
Digital Rehabilitation for Gastric Cancer Surgery After Neoadjuvant Therapy
The goal of this clinical trial is to investigate the effects of a perioperative multimodal rehabilitation program on the incidence of postoperative complications and perioperative clinical indexes including functional capacity…
- Trial name
- NCT07441850
- Testing
- perioperative multimodal rehabilitation program with telephone supervision, Usual Care, perioperative multimodal rehabilitation program with digital supervision
- Where
- China
- Volunteers
- 186 people
- Sponsor
- Beijing Friendship Hospital
Deep Venous Thrombosis, Colonic Cancer
Chemoprophylaxis With Rivaroxaban for Lower Limb Deep Vein Thrombosis in Colorectal Cancer
The chemoprophylaxis of deep vein thrombosis (DVT) with subcutaneous low-molecular-weight heparin (enoxaparin) in the postoperative period of elective surgeries is already well established in the literature and in clinical…
- Trial name
- Ésquilo (NCT05303818)
- Testing
- Rivaroxaban 10 MG
- Where
- Brazil
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Hospital do Servidor Publico Estadual
Colorectal Cancer
Psychological Predictors in Colorectal Cancer Surgery Recovery
This is an observation pilot trial aimed to study to the association between mindfulness and other psychological factors, including both protective and risk factors, with recovery of functional ability following colorectal cancer…
- Trial name
- MIND (NCT03781193)
- Testing
- Questionnaires administration, Five Facet Mindfulness Questionnaire (FFMQ), Langer Mindfulness Scale (LMS)
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Istituto Clinico Humanitas
Peritoneal Carcinomatosis, Colon Cancer
Metachonous Peritoneal Carcinomatosis Incidence After Curative Surgery for pT4 Colon Cancer Patients
This is an observational retrospective cohort study to determine metachronous peritoneal carcinomatosis in a specific subgroup of colon cancer patients, those with a final pathologic exam corresponding to pT4 tumors.
- Trial name
- NCT05300789
- Testing
- Follow-up
- Where
- Spain
- Volunteers
- 1,152 people
- Sponsor
- Carlos Cerdán Santacruz
Colon Cancer, Minimal Residual Disease
Effects of Different Types of Perioperative Analgesia on Minimal Residual Disease Development After Colon Cancer Surgery
The aim of this study is to compare the effects of three types of perioperative analgesia on the number of circulating cancer cells (representing minimal residual disease) following radical colon cancer surgery.
- Trial name
- NCT02314871
- Testing
- Epidural analgesia, Piritramide, Morphine
- Where
- 2 sites in Czechia
- Volunteers
- 60 people
- Sponsor
- The Institute of Molecular and Translational Medicine, Czech Republic
Liver Cancer
Value of 3D Printing for Comprehension of Liver Surgical Anatomy
To our knowledge, it has not been analyze whether 3D printed liver model would improve the perception of a given liver tumor or the precision of operation planning in liver surgery.
- Trial name
- NCT03153332
- Testing
- surgical residents' comprehension of the hepatic anatomy
- Where
- China
- Volunteers
- 59 people
- Sponsor
- Guangzhou Women and Children's Medical Center
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