Clinical trials: Gastroparesis
Idiopathic Gastroparesis
Effects of Global Osteopathic Manual Treatments in Patients With Idiopathic Gastroparesis
Global osteopathic manual treatments will decrease the severity score of the Gastroparesis Cardinal Symptom Index tool of patients with idiopathic gastroparesis.
- Trial name
- NCT02232334
- Testing
- Global Osteopathic Manual Treatment
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Kathleen Brannan Brown, Inc.
Gastroparesis, Diabetes Mellitus
Safety and Efficacy of IV Infusion of Investigational Agent (TZP-101) in Patients With Diabetic Gastroparesis
The purpose of this study is to determine whether TZP-101 is safe in people with diabetes. Also to determine if TZP-101 is effective in increasing the gastric emptying rate in diabetic patients.
- Trial name
- NCT00639808
- Testing
- 5% dextrose in water, TZP-101
- Where
- 3 sites in Denmark, Sweden
- Volunteers
- 10 people
- Sponsor
- Tranzyme, Inc.
Diabetic Gastroparesis
Thoracic Neuromodulation for Diabetic Gastroparesis
The global incidence of diabetes is rising. Gastroparesis is a significant complication of diabetes that results in debilitating symptoms and affects quality of life.
- Trial name
- TNM-DGp (NCT05273788)
- Testing
- 2400 ThorS-MagNT Stimulations at 1Hz, 2400 ThorS-MagNT Stimulations at 10Hz
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Medical University of South Carolina
Gastrointestinal Neoplasia, Hirschsprung's Disease
Prospective Evaluation of the Efficacy and Safety of Submucosal Endoscopy
To test the idea that submucosal endoscopy is effective and safe for endoscopic myotomy, endoscopic submucosal dissection, and access for tissue acquisition and resection.
- Conditions
- Gastrointestinal Neoplasia, Hirschsprung's Disease, Esophageal Obstruction, Gastroparesis
- Trial name
- NCT03626350
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- University of Colorado, Denver
Gastroparesis
Combined Role of Gastric Peroral Endoscopic Myotomy and Gastric Electrical Stimulator
This study is looking at how safe and effective G-POEM, GES and a combination of both are for people with severe stomach problems (gastroparesis) that haven't gotten better with medicine.
- Trial name
- NCT07526935
- Testing
- GES + Upper endoscopy, GES on + Upper endscopy, GES off + G-POEM
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Baylor Research Institute
Gastroparesis
Transpyloric Stenting as a Predictor for G-POEM for Refractory Gastroparesis
This is a prospective sham study to investigate the role of transpyloric stenting with lumen apposing metal stent (LAMS) as a predictor for clinical response to gastric per-oral endoscopic pyloromyotomy (GPOEM) for refractory…
- Trial name
- NCT04287647
- Testing
- Transpyloric stent
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Northwestern University
GERD, Gastroesophageal Reflux
Compassionate Use of Domperidone for Refractory Gastroparesis
The purpose of this program is to allow the use of domperidone in children from 12 to 21 years of age with symptoms related to motility disorders and Gastroesophageal reflux disease (GERD) who have failed all the standard…
- Conditions
- GERD, Gastroesophageal Reflux, Gastroparesis
- Trial name
- NCT04699591
- Testing
- Domperidone
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Jose Cocjin
Abdominal Pain
Gastric Electrical Stimulation for Abdominal Pain in Gastroparesis
To conduct a pilot study to evaluate the effects of new GES programming settings on abdominal pain in patients with gastroparesis and existing GES devices, whose abdominal pain has so far been refractory to drugs and/or devices.
- Trial name
- NCT04121325
- Testing
- Enterra
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- University of Louisville
Hip Fractures
Ultrasound Assessment of Gastric Contents in Fasted Elderly Patients With Hip Fracture
Evaluation of gastric contents in fasted elderly patients with hip fracture. The gastric contents will be examined by using ultrasonography in fasted elderly patients scheduled for hip fracture surgery.
- Trial name
- NCT03242733
- Testing
- Ultrasound assessment of gastric contents
- Where
- South Korea
- Volunteers
- 200 people
- Sponsor
- SMG-SNU Boramae Medical Center
Gastroparesis
Ultrasound Assessment of Gastric Contents in Fasted Surgical Patients With Previous Subtotal Gastrectomy
Investigators assess the gastric contents by ultrasonography in fasted patients with previous subtotal gastrectomy.
- Trial name
- NCT03802006
- Testing
- Ultrasound assessment of gastric content
- Where
- South Korea
- Volunteers
- 24 people
- Sponsor
- Seoul National University Hospital
Gastroparesis
GI-Challenge Study for Gastroparesis Patients and Healthy Controls
Gastroparesis Patients and Healthy Controls ages 20-49 will be asked to participate in an observational study measuring vagal activity following food ingestion in order to establish parameters of autonomic nerve/vagal function in…
- Trial name
- NCT03896126
- Testing
- Observational
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Stanford University
Pancreaticoduodenectomy, Delayed Gastric Emptying
Comparison Between Pylorus-resecting and Preserving Pancreaticoduodenectomy on Delayed Gastric Emptying and Nutrition
Pylorus preserving pancreaticoduodenectomy has been standard procedure for periampullary benign and malignant disease. Delayed gastric emptying is one of most common complications after the procedure.
- Conditions
- Pancreaticoduodenectomy, Delayed Gastric Emptying, Nutrition
- Trial name
- NCT05314244
- Testing
- Pylorus resecting pancreaticoduodenectomy
- Volunteers
- 394 people, healthy volunteers welcome
- Sponsor
- Asan Medical Center
Gastroparesis
The Use Of Domperidone For The Relief Of Refractory Upper Gastrointestinal GI Symptoms
To prescribe oral domperidone for patients with upper GI symptoms who have failed or suffered adverse effects from standard medical therapy.
- Trial name
- NCT03810287
- Testing
- Domperidone
- Where
- United States
- Sponsor
- Yale University
Gastroparesis, Gastroparesis Nondiabetic
Study of Enhanced Programming Stimulation with the Enterra® Therapy System
The purpose of this research study is to evaluate if an enhanced Enterra device programming strategy will improve symptoms associated with gastroparesis, improve symptoms in a faster amount of time, and improve quality of life…
- Conditions
- Gastroparesis, Gastroparesis Nondiabetic, Gastroparesis Due to Diabetes Mellitus
- Trial name
- EXPEDITE (NCT06560307)
- Testing
- Enterra Therapy System
- Where
- 6 sites in United States
- Volunteers
- 50 people
- Sponsor
- Enterra Medical, Inc.
Gastroparesis, Vomiting
Medico-economic Evaluation of ENTERRA Therapy
The aim of this clinical trial is to assess the symptomatic efficacy and the impact on the utilization of healthcare resources of a treatment by gastric electrical stimulation (ENTERRA ®) in patients with refractory nausea and/or…
- Conditions
- Gastroparesis, Vomiting, Nausea
- Trial name
- ENTERRA (NCT00903799)
- Testing
- Implantation of ENTERRA therapy
- Where
- 21 sites in France
- Volunteers
- 220 people
- Sponsor
- University Hospital, Rouen
Acupuncture, Ear, Gastroparesis
The Role of AAT After Abdominal Surgery Based on RWS
Delayed gastric emptying (DGE) after surgery mainly occurs after gastrointestinal surgery A functional gastric emptying disorder, clinically characterized by weak or absent gastric peristalsis, gastric motility disorders, or…
- Trial name
- NCT06580197
- Testing
- Auricular Acupoint Therapy
- Where
- China
- Volunteers
- 159 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Vomiting, Feeding Disorders
Use of Intrapyloric Botulinum Injections in Children
This study aims to evaluate the effect of intrapyloric botulinum toxin in children with feeding disorders.
- Conditions
- Vomiting, Feeding Disorders, Gastroparesis
- Trial name
- NCT04250844
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Boston Children's Hospital
Obesity, Weight Loss
Evaluation of Bariatric Endoscopic Antral Myotomy (BEAM) as a Treatment for Obesity
In the proposed study, we will be evaluating the effects of pylorus sparing antral myotomy alone, without concomitant endoscopic sleeve gastroplasty (ESG), on weight loss for subjects undergoing the procedure with a history of…
- Conditions
- Obesity, Weight Loss, Delayed Gastric Emptying Following Procedure, Obesity, Mild
- Trial name
- BEAM (NCT05713071)
- Testing
- Bariatric Endoscopic Antral Myotomy
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Brigham and Women's Hospital
Obesity, Obesity, Morbid
Endoscopic Metabolic and Bariatric Therapies
This is a prospective collection of data from adult patients who have had an endoscopic metabolic and bariatric endoscopy procedure (EMBT) for primary or revision surgical procedures for obesity.
- Conditions
- Obesity, Obesity, Morbid, Obesity Associated Disorder, Bariatric Surgery Candidate
- Trial name
- EMBTs (NCT05725967)
- Testing
- Primary Obesity Endoscopic Procedures, Endoscopic Revision of Bariatric Surgical Procedures, Bariatric Surgery Procedures
- Where
- United States
- Volunteers
- 5,000 people
- Sponsor
- Christopher C. Thompson, MD, MSc
Critical Illness, Intolerance; Nutritional
Clinical Evaluation of the VIPUN Balloon Catheter 0.2 in Critically Ill Patients
An open label, non-randomized, monocentric, interventional investigation in a cohort of adult critically ill patients
- Conditions
- Critical Illness, Intolerance; Nutritional, Delayed Gastric Emptying, Gastric Motor Dysfunction
- Trial name
- ANTERO-2 (NCT03512145)
- Testing
- VIPUN Balloon Catheter
- Where
- Belgium
- Volunteers
- 30 people
- Sponsor
- Prof Dr Jan Tack