Clinical trials: Gastroparesis Due to Diabetes Mellitus
Gastroparesis, Diabetes Mellitus
Study to Evaluate the Safety and Efficacy of Relamorelin in Participants With Diabetic Gastroparesis Study 02
This study will evaluate the safety and efficacy of relamorelin compared to placebo in participants with diabetic gastroparesis. Participants will report daily severity scores of their diabetic gastroparesis symptoms.
- Trial name
- NCT03426345
- Testing
- Relamorelin
- Where
- 240 sites in United States, Argentina and 13 more
- Volunteers
- 311 people
- Sponsor
- Allergan
Diabetic Gastroparesis
Continuous Glucose Monitoring and Insulin Pump Therapy in Diabetic Gastroparesis
A pilot study to assess the safety, feasibility, and potential (uncontrolled) efficacy of continuous glucose monitoring (CGMS) in conjunction with an insulin pump to improve glycemic control for treatment of type 1 and type 2…
- Trial name
- GLUMIT-DG (NCT01030341)
- Testing
- CGMS and insulin pump
- Where
- 7 sites in United States
- Volunteers
- 45 people
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Diabetes Mellitus, Diabetes Mellitus Complications
Safety and Efficacy of Relamorelin Administered to Participants With Vomiting Symptoms and Moderate to Severe Diabetic Gastroparesis
The purpose of this study is to evaluate the effects of multiple dose regimens of relamorelin on vomiting episodes, gastric emptying and gastroparesis symptoms in participants with Type 1 and Type 2 diabetes mellitus and…
- Conditions
- Diabetes Mellitus, Diabetes Mellitus Complications, Gastroparesis
- Trial name
- NCT02357420
- Testing
- Relamorelin
- Where
- 98 sites in United States, Belgium and 5 more
- Volunteers
- 393 people
- Sponsor
- Allergan
Gastroparesis, Diabetes Mellitus
A Safety and Efficacy Study of Relamorelin in Diabetic Gastroparesis 01
This study will evaluate the safety and efficacy of relamorelin compared to placebo in participants with diabetic gastroparesis. Participants will report daily severity scores of their diabetic gastroparesis symptoms.
- Trial name
- NCT03285308
- Testing
- Relamorelin
- Where
- 216 sites in United States, Australia and 12 more
- Volunteers
- 336 people
- Sponsor
- Allergan
Idiopathic Gastroparesis, Diabetic Gastroparesis
Evaluating the Safety and Efficacy of Tradipitant vs. Placebo in Idiopathic and Diabetic Gastroparesis
To investigate the safety and efficacy of tradipitant versus placebo in relieving nausea and other symptoms of gastroparesis.
- Conditions
- Idiopathic Gastroparesis, Diabetic Gastroparesis, Gastroparesis
- Trial name
- NCT04028492
- Testing
- Tradipitant, Open Label Tradipitant
- Where
- 36 sites in United States
- Volunteers
- 979 people
- Sponsor
- Vanda Pharmaceuticals
Diabetic Gastroparesis
Washed Microbiota Transplantation for Diabetic Gastroparesis
This is a randomized controlled trial to explore the efficacy and safety of washed microbiota transplantation (WMT) for diabetic gastroparesis (DGP) patients.
- Trial name
- NCT06340217
- Testing
- washed microbiota transplantation
- Where
- China
- Volunteers
- 46 people
- Sponsor
- The Second Hospital of Nanjing Medical University
Diabetes Mellitus, Gastroparesis With Diabetes Mellitus
Impact of Per Oral Pyloromyotomy (POP) on Glycemic Control in Diabetes
This study will assess changes in glycemic control in 40 patients with diabetes who undergo per-oral pyloromyotomy (POP) for medically refractory gastroparesis.
- Conditions
- Diabetes Mellitus, Gastroparesis With Diabetes Mellitus, Gastroparesis
- Trial name
- NCT04696159
- Testing
- Pyloromyotomy
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Matthew Allemang
Gastroparesis, Diabetic Gastroparesis
Efficacy and Safety of Metoclopramide Nasal Spray Solution in Diabetic Patients With Gastroparesis
To evaluate the safety and the effectiveness of two doses of metoclopramide nasal spray solution, 10 mg and 14 mg, compared to placebo in reducing the symptoms of diabetic gastroparesis.
- Conditions
- Gastroparesis, Diabetic Gastroparesis, Diabetes, Diabetes Mellitus
- Trial name
- NCT00845858
- Testing
- metoclopramide
- Where
- 65 sites in United States
- Volunteers
- 287 people
- Sponsor
- Evoke Pharma
Idiopathic Gastroparesis, Diabetic Gastroparesis
Intraluminal Endosonography for Examination of the Structural Changes of the Stomach in Gastroparetic Patients
Patients who empty their stomach slowly may have what we call "Slow gastric emptying" or "gastroparesis". These patients can have some changes in the thickness of their stomach wall.
- Trial name
- NCT01916460
- Testing
- Endoscopic Ultrasound Fine Needle Aspiration (EUS-FNA)
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Texas Tech University Health Sciences Center, El Paso
Diabetic Gastroparesis
A Study to Evaluate the Efficacy and Safety of CIN-102 (Deudomperidone) in Adults With Diabetic Gastroparesis
The goal of this clinical trial is to evaluate if the study drug CIN-102 (deudomperidone) can help reduce the symptoms associated with diabetic gastroparesis in adult patients.
- Trial name
- NCT05832151
- Testing
- CIN-102 Dose 15mg or 10mg
- Where
- 100 sites in United States
- Volunteers
- 382 people
- Sponsor
- CinDome Pharma, Inc.
Gastroparesis, Diabetic Gastroparesis
Gastroparesis Registry 3
The purpose of this study is to create a new registry of patients with gastroparesis in order to better understand the characteristics of patients with gastroparesis and follow how their condition changes over time.
- Conditions
- Gastroparesis, Diabetic Gastroparesis, Idiopathic Gastroparesis
- Trial name
- GpR3 (NCT03680859)
- Where
- 6 sites in United States
- Volunteers
- 406 people
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Gastroparesis Postoperative, Gastroparesis Due to Diabetes Mellitus
Gastric Per Oral Endoscopic Myotomy (G-POEM) in Refractory Gastroparesis
Refractory gastroparesis is a disease characterized by a delayed gastric emptying without a mechanical obstruction. Actual treatments have a limited efficacy and gastric per-oral endoscopic myotomy (G-POEM) is a new treatment…
- Conditions
- Gastroparesis Postoperative, Gastroparesis Due to Diabetes Mellitus, Idiopathic Gastric Stasis
- Trial name
- G-POEM (NCT03126513)
- Testing
- G-POEM
- Where
- Mexico
- Volunteers
- 82 people
- Sponsor
- Coordinación de Investigación en Salud, Mexico
Diabetic Gastroparesis
Evaluation of Diagnostic Methods and Dietary Treatment of Diabetic Gastroparesis
The objective of the study is in subjects with Insulin Treated Diabetes Mellitus type 1 or 2 and gastroparesis: validate radiopaque markers with fluoroscopy with gastric scintigraphy method study the difference of metabolic…
- Trial name
- NCT01557296
- Testing
- dietary treatment: food of small particle size, Validate X-ray diagnostic method., Can the motility be improved
- Where
- Sweden
- Volunteers
- 50 people
- Sponsor
- Göteborg University
Diabetic Gastroparesis
Thoracic Splanchnic Magnetic Neuromodulation Therapy (ThorS-MagNT) for Grade 3 Diabetic Gastroparesis: Pilot Study
Diabetic gastroparesis (DG) is an under recognized and significant complication of diabetes with lack of effective treatments. Recently, a 4-fold increase in hospitalizations has been seen in DG patients with refractory symptoms…
- Trial name
- ThorS-MagNT (NCT04706832)
- Testing
- Thoracic Splanchnic Magnetic Neuromodulation Therapy
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Augusta University
Gastroparesis
GI-Challenge Study for Gastroparesis Patients and Healthy Controls
Gastroparesis Patients and Healthy Controls ages 20-49 will be asked to participate in an observational study measuring vagal activity following food ingestion in order to establish parameters of autonomic nerve/vagal function in…
- Trial name
- NCT03896126
- Testing
- Observational
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Stanford University
Gastroparesis, Gastroparesis Postoperative
Laparoscopic Implantation of a Gastric Pacemaker in the Treatment of Gastroparesis
Gastroparesis is a burdensome condition that is caused by abnormal motor function of the stomach that results in delayed gastric emptying.
- Conditions
- Gastroparesis, Gastroparesis Postoperative, Gastroparesis Nondiabetic, Gastroparesis With Diabetes Mellitus
- Trial name
- NCT06661668
- Testing
- Gastric pacemaker (Enterra system) implantation
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- Evangelic Hospital Kalk Cologne
Diabetic Polyneuropathy, Diabetic Gastroparesis
Pilot Study to Evaluate Magnetic Marker Imaging on Diabetic Polyneuropathy and Gastroparesis
The purpose of this study is to determine whether Magnetic Marker Monitoring is an appropriate opportunity to diagnose and to quantify a suspicious gastroparesis in subjects with diabetic polyneuropathy.
- Conditions
- Diabetic Polyneuropathy, Diabetic Gastroparesis, Diabetes Mellitus
- Trial name
- NCT01607684
- Testing
- Magnetic Marker Imaging (MMI) with Magma 3D system
- Where
- Germany
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Martin-Luther-Universität Halle-Wittenberg
Gastroparesis, Diabetic Gastroparesis
Daily Tadalafil and Gastric Emptying Time in Diabetic Gastroparesis
The investigators hypothesize that in adult patients with diabetic gastroparesis with Type 1 diabetes (HbA1c ≤ 10.5%), daily tadalafil use will significantly improve gastric emptying compared to baseline as measured by gastric…
- Conditions
- Gastroparesis, Diabetic Gastroparesis, Nausea, Vomiting
- Trial name
- NCT01326117
- Testing
- tadalafil
- Where
- United States
- Sponsor
- Mark Feinglos
Diabetic Gastroparesis, Idiopathic Gastroparesis
G-POEM for Treatment of Refractory Gastroparesis
This study is performed to assess the efficacy and outcomes of Gastric Per Oral Endoscopic Myotomy "G-POEM" in patients presenting with gastroparesis.
- Conditions
- Diabetic Gastroparesis, Idiopathic Gastroparesis, Gastroparesis Postoperative
- Trial name
- NCT02732821
- Testing
- Gastric Per Oral Endoscopic Myotomy
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Johns Hopkins University
Diabetic Gastroparesis
Different Acupoints Compatibility Difference of the Effect of Treatment of the Diabetic Gastroparesis
With Diabetic gastroparesis as the research object, by the method of multi-center RCT and single cavity and different acupuncture acupoints compatibility treatment of diabetic gastroparesis, the inspection of gastric emptying…
- Trial name
- NCT02452489
- Testing
- acupuncture
- Where
- China
- Volunteers
- 99 people
- Sponsor
- Changchun University of Chinese Medicine