Clinical trials: Gastroparesis With Diabetes Mellitus
Gastroparesis Due to Diabetes Mellitus Type I
Pathophysiology of Diabetic Gastroparesis
The goal of this study is to explore the pathophysiology of diabetic gastroparesis by conducting an exploratory cohort study. Participants will be type 1 diabetes patients with and without gastroparesis.
- Trial name
- PATODIAG (NCT05717205)
- Testing
- technetium scitigraphy
- Where
- Denmark
- Volunteers
- 52 people
- Sponsor
- Hvidovre University Hospital
Gastroparesis, Diabetes Mellitus
A Safety and Efficacy Study of Relamorelin in Diabetic Gastroparesis Study 03
A 46-week study to compare the efficacy of relamorelin with that of placebo in participants with diabetic gastroparesis (DG). At the end of the 40-week Treatment Period, participants will either continue on relamorelin or placebo…
- Trial name
- NCT03420781
- Testing
- Relamorelin
- Where
- 337 sites in United States, Argentina and 24 more
- Volunteers
- 467 people
- Sponsor
- Allergan
Diabetic Gastroparesis, Idiopathic Gastroparesis
Effect of TAK-954 on Gastrointestinal and Colonic Transit in Diabetic or Idiopathic Gastroparesis Participants
The purpose of this study is to evaluate the dose-dependent effects of TAK-954 on gastric emptying time of solids in participants with diabetic or idiopathic gastroparesis assessed by scintigraphy.
- Trial name
- NCT03281577
- Testing
- TAK-954
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Takeda
Gastroparesis
A Phase 2 Study of CIN-102 in Adults With Idiopathic and Diabetic Gastroparesis
This is a randomized, double-blind, placebo-controlled Phase 2A study to evaluate safety, efficacy, PK, and dose response of oral CIN-102 in adults with idiopathic and diabetic gastroparesis.
- Trial name
- NCT04026997
- Testing
- CIN-102 Dose 1, CIN-102 Dose 2, CIN-102 Dose 3
- Where
- 19 sites in United States
- Volunteers
- 72 people
- Sponsor
- CinDome Pharma, Inc.
Gastroparesis, Diabetes Mellitus
Safety and Efficacy of Once-daily Oral Administrations of TZP-102 for Gastroparesis in Patients With Diabetes Mellitus
The purpose of this study is to evaluate the effect of TZP-102 on gastric emptying rate, gastroparesis symptoms and health-related quality of life in diabetic patients with gastroparesis.
- Trial name
- NCT00889486
- Testing
- TZP-102
- Where
- 23 sites in United States, Denmark and 4 more
- Volunteers
- 92 people
- Sponsor
- Tranzyme, Inc.
Gastroparesis, Gastroparesis Postoperative
Safety and Efficacy of GPOEM in the Treatment of Gastroparesis
The purpose of this study is to assess the clinical efficacy and safety in the treatment of gastroparesis.
- Conditions
- Gastroparesis, Gastroparesis Postoperative, Gastroparesis With Diabetes Mellitus
- Trial name
- NCT04349670
- Testing
- GPOEM - gastric per-oral endoscopic myotomy
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- IRCCS San Raffaele
Crohn Disease, Diabetic Gastroparesis
Rifaximin in Patients With Diabetic Gastroparesis
Researchers are trying to determine if subjects with diabetic gastroparesis and symptoms of bloating will have a greater improvement in bloating symptoms when treated with rifaximin.
- Trial name
- NCT04254549
- Testing
- Rifaximin
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Mayo Clinic
Gastroparesis
Itopride Hydrochloride in Diabetes: Effects on Gastric Emptying and Glycemia
Itopride is a new compound that is already marketed in Japan and in some countries of Eastern Europe under the name of Ganaton. It is used to treat symptoms associated with gastroparesis.
- Trial name
- NCT00370084
- Testing
- Itopride
- Where
- Australia
- Volunteers
- 25 people
- Sponsor
- Forest Laboratories
Gastroparesis, Gastroparesis Nondiabetic
Study of Enhanced Programming Stimulation with the Enterra® Therapy System
The purpose of this research study is to evaluate if an enhanced Enterra device programming strategy will improve symptoms associated with gastroparesis, improve symptoms in a faster amount of time, and improve quality of life…
- Conditions
- Gastroparesis, Gastroparesis Nondiabetic, Gastroparesis Due to Diabetes Mellitus
- Trial name
- EXPEDITE (NCT06560307)
- Testing
- Enterra Therapy System
- Where
- 6 sites in United States
- Volunteers
- 50 people
- Sponsor
- Enterra Medical, Inc.
Gastroparesis
G-POEM for Glycemic Control in Diabetic Gastroparesis
Gastroparesis, commonly caused by diabetes, affects 30-50% of diabetic individuals and complicates glycemic control due to its bidirectional relationship with blood glucose levels. Current treatments are often ineffective.
- Trial name
- DIAPOEM (NCT06965543)
- Testing
- Immediate G-POEM, Delayed G-POEM
- Volunteers
- 40 people
- Sponsor
- French Society of Digestive Endoscopy
Gastroparesis, Diabetes Mellitus
Safety and Efficacy of IV Infusion of Investigational Agent (TZP-101) in Patients With Diabetic Gastroparesis
The purpose of this study is to determine whether TZP-101 is safe in people with diabetes. Also to determine if TZP-101 is effective in increasing the gastric emptying rate in diabetic patients.
- Trial name
- NCT00639808
- Testing
- 5% dextrose in water, TZP-101
- Where
- 3 sites in Denmark, Sweden
- Volunteers
- 10 people
- Sponsor
- Tranzyme, Inc.
Weight Loss, Diabetic Gastroparesis
Potential Benefits of Sleeve Gastrectomy Surgery on Diabetic Gastroparesis Symptoms
The purpose of this registry is to evaluate if sleeve gastrectomy surgery will help with symptoms of delayed gastric emptying for patients suffering from diabetic gastroparesis.
- Conditions
- Weight Loss, Diabetic Gastroparesis, Bariatric Surgery Candidate, Sleeve Gastrectomy
- Trial name
- NCT03376399
- Testing
- Gastroparesis Cardinal Symptom Index Questionnaire
- Where
- United States
- Sponsor
- Baylor Research Institute
Diabetic Gastroparesis
The Effect of Acupuncture on Symptoms, Gastric Emptying Rate and Glucose Control in Patients With Diabetic Gastroparesis
Diabetes affects 5.8% of the adult population in Israel (1). Gastroparesis is a syndrome characterized by delayed gastric emptying in the absence of mechanical obstruction of the stomach.Treatment with acupuncture has been…
- Trial name
- NCT00874133
- Testing
- Acupuncture, Motilium
- Volunteers
- 8 people
- Sponsor
- Rabin Medical Center
Diabetic Gastroparesis
Docusate/Senna for the Treatment of Diabetic Gastroparesis
The aim of the study is to evaluate the efficacy of the stimulant laxative Senokot-S® for the treatment of diabetic gastroparesis.
- Trial name
- NCT03342157
- Testing
- senna/docusate
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Wake Forest University Health Sciences
Diabetic Gastroparesis
Multicenter Study to Evaluate the Efficacy and Safety of Metoclopramide Nasal Spray in Men With Diabetic Gastroparesis
The purpose of this study is evaluate the safety and efficacy of Metoclopramide Nasal Spray compared to placebo in reducing the symptoms of diabetic gastroparesis in adult men.
- Trial name
- NCT02025751
- Testing
- Metoclopramide Nasal Spray
- Where
- 49 sites in United States
- Volunteers
- 53 people
- Sponsor
- Evoke Pharma
Gastroparesis, Diabetic Gastroparesis
Gastroparesis Registry 2
To expand a registry of patients for the study of the epidemiology, etiology, and degree of morbidity associated with gastroparesis.
- Conditions
- Gastroparesis, Diabetic Gastroparesis, Idiopathic Gastroparesis
- Trial name
- GpR2 (NCT01696747)
- Where
- 6 sites in United States
- Volunteers
- 506 people
- Sponsor
- Johns Hopkins Bloomberg School of Public Health