Clinical trials: Gastropathy
Diabetes Mellitus and Gastroparesis, Idiopathic Gastroparesis
A Study to Evaluate the Safety, Pharmacokinetics (PK) and Pharmacodynamics (PD) for TAK-906 in Participants With Diabetes Mellitus and Gastroparesis (DG) or With Idiopathic Gastroparesis (IG)
The purpose of this study is to evaluate the safety, PK and PD of TAK-906 in participants with Gastroparesis (GP).
- Trial name
- NCT03268941
- Testing
- TAK-906 Maleate, Metaclopramide
- Where
- 9 sites in United States
- Volunteers
- 51 people
- Sponsor
- Millennium Pharmaceuticals, Inc.
Esophageal Cancer, Stomach Cancer
Study to Evaluate the Efficacy of Pravastatin on Survival and Recurrence of Advanced Gastroesophageal Cancer
The survival of esophageal cancer and stomach cancer (EGC) at 5 years is less than 30%. Pravastatin is a potent inhibitor of HMG-CoA reductase inhibitor that has shown increased survival in patients with advanced hepatocellular…
- Trial name
- AGIM-1 (NCT01038154)
- Testing
- Pravastatin
- Where
- Spain
- Volunteers
- 146 people
- Sponsor
- Hospital Donostia
Watermelon Stomach
Cyrotherapy vs. APC in GAVE
To see if either method of treatment for Watermelon Stomach shows better results
- Trial name
- NCT00587405
- Testing
- cryotherapy, Argon Plasma Coagulation
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Mayo Clinic
Gastric Cancer
XParTS: Capecitabine/Cisplatin(XP) for Recurrent Gastric Cancer
The aim of this study is to evaluate efficacy and safety of Capecitabine/Cisplatin for gastric cancer patients who relapsed after adjuvant chemotherapy by S-1.
- Trial name
- NCT01412294
- Testing
- Capecitabine, Cisplatin
- Where
- Japan
- Volunteers
- 40 people
- Sponsor
- Epidemiological and Clinical Research Information Network
Helicobacter Infections
Endofaster Test for Helicobacter Pylori Detection in Patients on Proton Pump Inhibitor Therapy
H. pylori infection is the most important causative agent of gastritis, and subsequent atrophic gastritis. The endoscopic diagnosis of H. pylori infection relies on urease tests such as the Clo test.
- Trial name
- NCT02126722
- Testing
- Gastroscopy, EndoFaster test, Clo test
- Where
- United Kingdom
- Volunteers
- 150 people
- Sponsor
- Niso Biomed S.R.L.
Gastric Cancer
The Advantages and Disadvantages of Linear Anastomat and Tubular Anastomat in Radical Gastrectomy of Distal Gastric Cancer
The goal of this clinical trial is to observe and compare the short-term complications, long-term survival and quality of life of linear anastomat and tubular anastomat during digestive tract reconstruction after resection of…
- Trial name
- NCT07080879
- Testing
- Linear Anastomat, Tubular Anastomat
- Where
- China
- Volunteers
- 250 people
- Sponsor
- Xiangya Hospital of Central South University
Esophagectomy, No Signs of Cancer Recurrence
Pylorus Dysfunction After Esophagectomy and Gastric Tube Reconstruction. Effect of Pneumatic Pylorus Dilatation During Hospital Stay, Surgical Complications During in Hospital Stay
Delayed emptying of the gastric tube after esophagectomy is a frequent and durable problem. No treatment is currently available.
- Conditions
- Esophagectomy, No Signs of Cancer Recurrence, Delayed Gastric Emptying
- Trial name
- NCT02086461
- Testing
- Pneumatic pyloric dilatation, 15 mm pyloric balloon dilatation
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- Karolinska University Hospital
Gastric or Gastroesophageal Junction Adenocarcinoma
Neoadjuvant Toripalimab for dMMR/MSI-H Gastric Cancer
This is a single-center, open phase II clinical trial to evaluate the tolerability, safety and efficacy of toriparib monotherapy in the treatment of locally advanced dMMR/MSI-H gastric or gastroesophageal junction adenocarcinoma.
- Trial name
- NCT05994456
- Testing
- PD-1 inhibitor
- Where
- China
- Volunteers
- 24 people
- Sponsor
- Sun Yat-sen University
Gastric Cancer
Analgesia Nociception Index-guided Anesthesia and Standard Anesthesia
The primary purpose of this study is to compare the analgesia nociception index-guided anesthesia and standard anesthesia on remifentanil requirement in desflurane anesthesia.
- Trial name
- NCT06123637
- Testing
- Analgesia nociception index-guided anesthesia, Standard anesthesia
- Volunteers
- 68 people
- Sponsor
- Ajou University School of Medicine
Gastric Cardia Adenocarcinoma, Gastroesophageal Junction Adenocarcinoma
Pembrolizumab, Combination Chemotherapy, and Radiation Therapy Before Surgery in Treating Adult Patients With Locally Advanced Gastroesophageal Junction or Gastric Cardia Cancer That Can Be Removed by Surgery
This phase Ib/II trial studies the side effects and best way to give pembrolizumab with combination chemotherapy and radiation therapy before surgery and to see how well it works in treating adult patients with gastroesophageal…
- Conditions
- Gastric Cardia Adenocarcinoma, Gastroesophageal Junction Adenocarcinoma, Stage IB Gastric Cancer AJCC v7, Stage II Gastric Cancer AJCC v7
- Trial name
- NCT02730546
- Testing
- Carboplatin, Computed Tomography, Fluorouracil
- Where
- 2 sites in United States
- Volunteers
- 31 people
- Sponsor
- Mayo Clinic
Gastric Cancer
Comparison of the Effects of Continuous Epidural Analgesia and Continuous Intravenous Analgesia on Postoperative Bowel Movement in Patients Undergoing Laparoscopic Gastrectomy
The investigators hypothesized that sympatholytic effect of epidural analgesia would attenuate the hemodynamic instability and decrease in the splanchnic blood flow caused by pneumoperitoneum during laparoscopic surgery.
- Trial name
- NCT02458573
- Testing
- continuous epidural analgesia, continuous intravenous analgesia
- Where
- South Korea
- Volunteers
- 86 people
- Sponsor
- Yonsei University
Gastric Cancer, GastroEsophageal Cancer
Efficacy and Safety of Sintilimab Combined With Nab-paclitaxel and Tegio (aTS) as First-line Treatment of Unresectable Locally Advanced, Recurrent or Metastatic Adenocarcinoma of Gastric and Gastroesophageal Junction，a Phase II Clinical Study
The goal of this clinical trial is to find better protocal for adenocarcinoma of the gastric and gastroesophageal juncion. The main question is aim to answer is: 1.
- Conditions
- Gastric Cancer, GastroEsophageal Cancer, Adenocarcinoma
- Trial name
- NCT06241469
- Testing
- Sintilimab,nab-paclitaxel and tegio
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Wu Jun
Bleeding at Gastric Cancer
Role of Hemostatic Powder (Endo-clotTM) in Success and Prevention of Bleeding Within Gastric Cancer Patients With Bleeding
Gastrointestinal(GI) hemorrhage related with gastric cancer is prevalent in advanced cases mostly. As endoscopic hemostatic methods such as argon plasma ablation (APC) had developed, controlling GI hemorrhage in gastric cancer is…
- Trial name
- NCT02732483
- Testing
- Endo-Clot(TM)
- Where
- South Korea
- Volunteers
- 32 people
- Sponsor
- Yonsei University
Gastric Cancer, Molecular Imaging
Novel Humanized Ferritin-based NIR Fluorescent Molecular Probe for Identifying Tumor Margins in Gastric Tissue
Radical surgery remains the primary treatment for gastric cancer, but intraoperative tumor margin assessment relies on surgeons' visual inspection, limiting accuracy.
- Trial name
- NCT07276854
- Testing
- Diagnostic Test: ICG-FTn perfusion solution
- Where
- China
- Volunteers
- 32 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Gastric Cancer
Antiangiogenic Factors in Gastric Cancer
Endogenous antiangiogenic factors are related with gastric cancer progression.
- Trial name
- NCT00735566
- Where
- South Korea
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- National Cancer Center, Korea
Gastrointestinal Cancer
68Ga-PMD22 PET/CT Examination Targeting CLDN18.2
To investigate the ability of the CLDN18.2-targeted 68Ga-PMD22 tracer to detect CLDN18.2 expression in patients with gastric and colorectal cancer and other gastrointestinal tumours.
- Trial name
- NCT05937919
- Testing
- Intravenous injection of 68Ga-PMD22
- Where
- China
- Volunteers
- 10 people
- Sponsor
- Peking Union Medical College Hospital
Colorectal Neoplasm, Gastric Neoplasm
A Phase I Study of S-1 Plus Irinotecan and Oxaliplatin in Advanced Gastrointestinal Malignancy
This study is an open-label, single center, and a dose-escalating phase I study to determine the maximal tolerated dose and the recommended dose of S-1 combined with irinotecan/oxaliplatin in patients with unresectable or…
- Conditions
- Colorectal Neoplasm, Gastric Neoplasm, Secondary
- Trial name
- TIROX (NCT00506207)
- Testing
- S-1, Irinotecan, Oxaliplatin
- Where
- South Korea
- Volunteers
- 23 people
- Sponsor
- National Cancer Center, Korea
Stomach Neoplasms
Study of Adjuvant Radiochemotherapy for Gastric Cancer
In 1991, the South West Oncology Group (SWOG) conducted a randomized study of adjuvant chemotherapy (5-fluorouracil and folinic acid) with concurrent radiation (4500 cGy/25 fractions) versus surgery alone for patients with…
- Trial name
- NCT00188266
- Testing
- cisplatinum combined with infusional fluorouracil (5 FU)
- Where
- Canada
- Volunteers
- 65 people
- Sponsor
- University Health Network, Toronto
Gastrointestinal Neoplasms, Gynecologic Cancers
Collection of Biospecimen & Clinical Information in Patients w/ Gastrointestinal Cancers
We have an active research program in gastrointestinal cancers including clinical trials, epidemiologic, and translational studies.
- Conditions
- Gastrointestinal Neoplasms, Gynecologic Cancers, Gynecologic Cancers Cervical Cancer, Gastric (Stomach) Cancer
- Trial name
- NCT01031056
- Testing
- Blood Draw, Frozen Tumor Specimens
- Where
- United States
- Sponsor
- Stanford University
Gastroesophageal Reflux Disease
Mass Balance Study of [14C]X842 in Healthy Adult Male Subjects
This study is a single-site, single-dose, non-randomized, open-label study to assess the absorption, metabolism, and excretion profile of [14C]X842 in healthy adult male subjects.
- Trial name
- NCT07107672
- Testing
- [14C]X842
- Where
- China
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Jiangsu Sinorda Biomedicine Co., Ltd