Clinical trials: Gastroscopy
Anesthesia
Ketamine and Propofol for Upper Endoscopy
The purpose of this study is to examine the dose-response relationship of ketamine in combination with propofol.
- Trial name
- NCT02295553
- Testing
- Ketamine, Propofol
- Where
- Canada
- Volunteers
- 56 people
- Sponsor
- The Hospital for Sick Children
Patients Requiring Diagnostic Gastroscopy With Sedation
A Single-centre Study of Entonox Versus Midazolam Sedation in Gastroscopy
This study aims to determine whether Entonox (gas and air) is at least as good as intravenous midazolam in providing analgesia and sedation during gastroscopy.
- Trial name
- NCT01744184
- Testing
- Entonox, Midazolam
- Where
- United Kingdom
- Volunteers
- 62 people
- Sponsor
- The Royal Bournemouth Hospital
Gastrointestinal Hemorrhage
Video Capsule Endoscopy Versus Colonoscopy in Patients With Melena and Negative Upper Endoscopy
Acute gastrointestinal bleeding is a common medical problem. When patients with gastrointestinal bleeding present with melena (dark, tarry stool) the blood loss is usually originating in the upper gastrointestinal tract…
- Trial name
- NCT02609100
- Testing
- Video Capsule Endoscopy, Colonoscopy, 1.0 X 2.5 cm 'pill' containing a camera
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Washington University School of Medicine
Diabetes Mellitus, Type 2, Obesity
Holding vs. Continuing Incretin-based Therapies Before Upper Endoscopy
To assess whether holding incretin-based therapy before endoscopy reduces the likelihood of clinically relevant Residual Gastric Volume (RGV).
- Conditions
- Diabetes Mellitus, Type 2, Obesity, Gastroparesis
- Trial name
- NCT06533527
- Testing
- GLP-1 medication
- Where
- 2 sites in United States
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Esophageal Varices
Wired Magnetically Assisted Capsule Endoscopy and Esophageal Varices
The goal of this clinical trial is to compare the safeness and effectiveness of traditional esophagogastroduodenoscope (EGD) and wired magnetically assisted capsule endoscopy (MACE) in the diagnosis of esophageal varices in…
- Trial name
- NCT06017102
- Testing
- wired magnetic assisted capsule endoscopy, esophagogastroduodenoscopy
- Where
- Taiwan
- Volunteers
- 50 people
- Sponsor
- National Taiwan University Hospital
Severe Obesity, Hypoxia
Use of Non-Invasive Positive Pressure Ventilation in Patients With Severe Obesity Undergoing Upper Endoscopy Procedures
The study evaluated the effect of non-invasive positive pressure ventilation (NIPPV) to decrease the incidence of desaturation events in patients with severe obesity undergoing upper endoscopy.
- Trial name
- NCT03529461
- Testing
- Non-invasive positive pressure ventilation through nasal mask, Rescue non-invasive positive pressure ventilation through nasal mask, Secondary rescue maneuvers
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Bristol Hospital
Upper Gastrointestinal Symptoms
Comparative Study of MCCE With/Without Tether vs Conventional Upper Endoscopy in Patients With Upper Abdominal Symptoms
A prospective single blinded, tandem study, comparing a magnetically controlled capsule with or without a tether (MCC or MCC-T) with conventional upper endoscopy for the diagnosis of patients with upper abdominal symptoms.
- Trial name
- NCT04605302
- Testing
- MCC/MCC-T, Standard gastroscopy
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- AnX Robotica Corp.
Barrett Esophagus
Cap Assisted Upper Endoscopy Versus High Definition White Light Endoscopy and Narrow Band Imaging Alone In The Detection Of Visible Lesions Barrett's Esophagus: A Randomized Tandem Study
The hypothesis is that the addition of a transparent cap to the end of the endoscope will increase the detection and diagnostic yield of visible lesions in Barrett's esophagus.
- Trial name
- NCT03417570
- Testing
- Esophagogastroduodenoscopy with high definition-white light end endoscopy (HD-WLE) and narrow band imaging (NBI), Olympus Disposable Distal Attachment Cap
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Washington University School of Medicine
Capsule Endoscopy
The Second-Generation MCCG for Upper Gastrointestinal Tract.
The aim of this study is to evaluate the clinical application of the second-generation MCCG with higher image resolution and frame rate for upper gastrointestinal tract compared with the first-generation.
- Trial name
- NCT03977935
- Testing
- the second-generation MCCG
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Changhai Hospital
Lesion of Stomach
Small Volume Simethicone Before Gastroscopy: Any Benefit?
A randomized controlled and endoscopist-blinded study which compares the efficacy of liquid simethicone (100mg) in 5 mls water, versus placebo ( 5mls of water), as premedication (given at least 30 minutes) before gastroscopy…
- Trial name
- NCT02555228
- Testing
- Simethicone, Water
- Where
- Singapore
- Volunteers
- 54 people
- Sponsor
- Changi General Hospital
Upper Gastrointestinal Bleeding
Capsule Endoscopy for HEmorrhage in the ER
This is a multi-center randomized controlled trial examining the use of Video Capsule Endoscopy (VCE) to discharge low-moderate risk patients with suspected upper gastrointestinal bleeds (UGIB) from the Emergency Department (ED.)…
- Trial name
- CHEER (NCT03458000)
- Testing
- PillCam UGI, Standard of Care
- Where
- 3 sites in United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- George Washington University
Endoscopy, Digestive System, Airway Anesthesia
Evaluating the Efficiency and Tolerability of the Oxygenating Bite Block
This study will test an investigational bite block, which is a device placed inside the mouth to protect the teeth and used to keep the endoscope (a long, flexible tube that is placed down the throat and into the esophagus that…
- Conditions
- Endoscopy, Digestive System, Airway Anesthesia, Airway Control, Airway Management
- Trial name
- OBB (NCT07086378)
- Testing
- Oxygenating Bite Block
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Cedars-Sinai Medical Center
Endoscopy
Is End Tidal CO2 Level Elevation During Upper Endoscopy With CO2 Gas Insufflation Physiologically Significant
During the course of an endoscopic procedure, air has historically been used to inflate the lumen to provide adequate visualization and allow for the endoscope to advance as necessary.
- Trial name
- ETCO2 (NCT04541667)
- Testing
- Air, Carbon Dioxide
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- University of Nebraska
Infectious, Gastro-Intestinal Disorder
Aerosolization During Upper Endoscopy
Given the current Covid-19 pandemic alongside the lack of evidence on aerosolization during upper endoscopy the investigators are conducting a randomized controlled trial seeking to assess both the level of aerosolization that…
- Conditions
- Infectious, Gastro-Intestinal Disorder, Safety Issues
- Trial name
- NCT06006078
- Testing
- Endoscopic Patient Facemask
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- Anthony Lembo