Clinical trials: Gastroscopy, open to volunteers
Upper Endoscopy, GLP1-R-related Disease
Effect of Prolonged Fasting Time on Gastric Residual Volume in Patients Taking GLP1 Receptor Agonists
The aim of this study is to determine whether a modified fasting protocol can reduce the potential risk of aspiration for patients currently prescribed GLP1-RAs.
- Trial name
- NCT07006142
- Testing
- Modified Fasting Guidelines
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Mayo Clinic
Euphoria, Remimazolam Besylate
Study on the Feelings of Euphoria Caused by Remimazolam During Gastroscopy and Colonoscopy and Their Related Factors
This study aims to investigate the incidence of euphoria induced by remimazolam during gastrointestinal endoscopy and explore its related factors.
- Conditions
- Euphoria, Remimazolam Besylate, Gastrointestinal Endoscopy
- Trial name
- ERGE (NCT06721195)
- Testing
- Remimazolam for Gastrointestinal Endoscopy Sedation
- Where
- China
- Volunteers
- 305 people
- Sponsor
- Zhangjie Yu
Gastritis, Gastric Dysplasia
A Cohort Study of Mobile Capsule Gastroscopy for Gastric Pathologies Screening
The goal of this is to learn about the effectiveness and feasibility of a novel AI- assisted Mobile Capsule Gastroscopy (MCG) system for detecting gastric pathologies in elderly and high-risk populations.
- Conditions
- Gastritis, Gastric Dysplasia, Gastric Ulcer, Gastric Cancer
- Trial name
- NCT07032961
- Testing
- Collect epidemiological, diagnostic, and follow-up data after MCG examination.
- Where
- China
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Nanfang Hospital, Southern Medical University
Upper Gastrointestinal Disorder
Endoscopists' Perspectives on the Use of Single-Use Gastroscopes in Elective and Subacute Patients in the Endoscopy Unit
The aim of this clinical trial is to investigate whether single-use gastroscopes perform comparably to reusable gastroscopes when used in an endoscopy unit during a period of reduced endoscope reprocessing capacity.
- Trial name
- NCT07727226
- Testing
- Ambu aScope Gastro, Reusable diagnostic gastroscopes (Olympus)
- Where
- Denmark
- Volunteers
- 300 people
- Sponsor
- Zealand University Hospital
Sedation
The Impact of Long-term High-risk Drinking on the Effective Dose of Osselidin
this study aims to investigate the effect of chronic high-risk alcohol consumption on the effective dose of oliceridine combined with propofol for painless gastroscopy, so as to provide a reference for rational clinical…
- Trial name
- NCT07880899
- Testing
- long-term high-risk drinking, non-drinking
- Where
- China
- Volunteers
- 110 people
- Sponsor
- Affiliated Hospital of Jiaxing University
Gastric Mucosal Lesion
Efficacy and Safety of OsrhCT Before Upper Endoscopy on Improving Visualization of the Gastric Mucosa.
Study was designed to evaluate efficacy and safety of OsrhCT before upper endoscopy on visibility of gastric mucosa. A total of 40 subjects (both male and female) are expected to be enrolled in this trial.
- Trial name
- NCT07893600
- Testing
- Recombinant Human Chymotrypsin(OsrhCT) 4000U
- Volunteers
- 40 people
- Sponsor
- Healthgen Biotechnology Corp.
Postoperative Hypoxemia
Effect of Lateral Versus Supine Positions on Postoperative Hypoxemia
Using prospective real-world data, this study aims to determine whether the lateral decubitus position reduces the incidence of post-procedure hypoxemia in patients undergoing painless gastroscopy/colonoscopy, thereby providing a…
- Trial name
- NCT07545642
- Testing
- Lateral decubitus position group (Group L), Supine position group (Group S)
- Where
- China
- Volunteers
- 960 people
- Sponsor
- General Hospital of Ningxia Medical University
Gastrointestinal Endoscopy
Etomidate Combined With Propofol Versus Propofol for Sedation in High-Altitude Patients During Gastroscopy: a Randomized Multicenter Clinical Trial
One of the most common adverse events during sedated gastrointestinal endoscopy is hypoxemia, which can lead to serious consequences.
- Trial name
- NCT07079176
- Testing
- etomidate combined with propofol, propofol
- Volunteers
- 732 people
- Sponsor
- RenJi Hospital
Sedation for Diagnostic Gastroscopy
Remimazolam Versus Midazolam for Sedation During Upper GI Endoscopy: a Randomized Controlled Trial
Rationale Midazolam is known for its safety, effectiveness for procedural sedation during gastrointestinal (GI) endoscopy and is used as standard sedative by endoscopists worldwide.
- Trial name
- REST (NCT06614036)
- Testing
- Remimazolam, Midazolam
- Where
- 3 sites in Netherlands
- Volunteers
- 148 people
- Sponsor
- Koen Munters
Postoperative Hypoxemia
Effect of Different Body Positions on Hypoxemia During Recovery in Patients Undergoing Painless Gastroscopy and Colonoscopy
Through a multicenter, three-arm randomized controlled trial design, this study aimed to compare the effects of three positioning strategies-side-lying with elevated head position, supine with elevated head position, and standard…
- Trial name
- NCT07587970
- Testing
- lateral decubitus head-up position (LH group), supine head-up position (SH group), standard lateral decubitus position group (SL group)
- Where
- China
- Volunteers
- 1,617 people
- Sponsor
- General Hospital of Ningxia Medical University
Heterotopic Gastric Mucosa of the Proximal Esophagus, Gastric Inlet Patches
Symptoms and Quality of Life in Patients With Heterotopic Gastric Mucosa (HGM)
The goal of this observational study is to learn whether heterotopic gastric mucosa (HGM) in the upper esophagus is associated with swallowing difficulties (dysphagia) in adults undergoing a medically indicated gastroscopy.
- Conditions
- Heterotopic Gastric Mucosa of the Proximal Esophagus, Gastric Inlet Patches, Dysphagia, Dyspepsia
- Trial name
- SYM-HGM (NCT07510984)
- Where
- Germany
- Volunteers
- 721 people
- Sponsor
- Knappschaft Kliniken GmbH
Acute Pancreatitis (AP)
ENDoscopic Assessment in Acute PANcreatitis Study (ENDOPAN Study)
This is a prospective observational cohort study designed to evaluate early upper gastrointestinal endoscopic findings in adult patients hospitalized with acute pancreatitis.
- Trial name
- NCT07714850
- Where
- Poland
- Volunteers
- 200 people
- Sponsor
- Jan Kochanowski University
Adverse Respiratory Events, Hypoxemia
Comparing Esketamine and Remazolam With Propofol for Breathing Safety in Pediatric Gastroscopy
Gastroscopy is important for diagnosing and treating upper gastrointestinal diseases in children. To ensure the procedure is safe and smooth, most children require sedation.
- Conditions
- Adverse Respiratory Events, Hypoxemia, Children, Gastroscopy
- Trial name
- NCT07748884
- Testing
- Fentanyl and Propofol, Esketamine and remimazolam
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
High Flow Nasal Cannula, Body Roundness Index
High Flow Nasal Cannula and Mask Oxygenation in Patients With Visceral Obesity Undergoing Sedated Gastroscopy
During sedated gastroscopy, the insertion of the fiberscope and gastric distension required to perform the examination may induce respiratory depression, airway obstruction, and decreased chest wall compliance.
- Trial name
- NCT07159022
- Testing
- High Flow Nasal Cannula Oxygenation, Face Mask Oxygenation
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Shanghai Zhongshan Hospital
Hypoxia, Obesity
Nasopharyngeal Airway Combined With Nasal High-flow Oxygen Therapy During Painless Gastroscopy in Obesity Patients
Gastroscopy is a commonly used, direct, and reliable method for screening and diagnosing digestive tract diseases. However, as an invasive examination, it can cause adverse reactions such as pain, nausea, vomiting, and choking…
- Conditions
- Hypoxia, Obesity, Gastrostomy
- Trial name
- NCT06966934
- Testing
- NPA
- Where
- China
- Volunteers
- 364 people
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Gastroscopy, Colonoscopy
A Clinical Trial to Evaluate the Efficacy and Safety of Methoxyethyl Etomidate Hydrochloride for Sedation/Anesthesia During Gastroscopy/Colonoscopy
A total of 270 subjects undergoing gastroscopy/colonoscopy were randomly assigned to the methoxetomidate hydrochloride group and the etomidate group according to the ratio of 2:1 with etomidate as the control group.Neither the…
- Trial name
- NCT06858852
- Testing
- ET-26HCl 0.8mg/kg group, Etomidate Injectable Product 0.3mg/kg group
- Where
- 6 sites in China
- Volunteers
- 270 people
- Sponsor
- Ahon Pharmaceutical Co., Ltd.
Stomach Cancer, Diagnosis
Evaluation of the NEOmom® Gastric Video Capsule for Gastric Cancer Screening
Gastric cancer remains a major public health concern, with approximately 6,600 new cases diagnosed each year in France. Despite therapeutic progress, its overall prognosis is still poor: the 5-year survival rate across all stages…
- Conditions
- Stomach Cancer, Diagnosis, Endoscopy of Stomach (Procedure)
- Trial name
- NEOTOGAS (NCT07323186)
- Testing
- Magnetically controlled video capsule endoscopy (MC-VCE)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Nantes University Hospital
Stomach Neoplasms, Stomach Diseases
One-Click Autofocus Versus Segmented Focus in Gastric Endoscopy
Magnifying endoscopy provides high-resolution images that enhance the detection of early gastrointestinal lesions. However, conventional manual zoom techniques require frequent focal adjustments, which can be technically…
- Trial name
- NCT07664813
- Testing
- One-Click Autofocus, Segmented Focus
- Where
- China
- Volunteers
- 93 people
- Sponsor
- Shandong University
Pediatric Gastrointestinal Disorders, Chronic Abdominal Pain in Children
Role and Diagnostic Yield of Upper Endoscopy in Children With Chronic Abdominal Pain
Chronic abdominal pain is a common problem in children and may be caused by functional or organic gastrointestinal disorders. While many children have no identifiable structural disease, some may have conditions that can be…
- Conditions
- Pediatric Gastrointestinal Disorders, Chronic Abdominal Pain in Children, Upper Endoscopy
- Trial name
- UGI-CAP (NCT07372976)
- Testing
- Upper Gastrointestinal Endoscopy
- Where
- Egypt
- Volunteers
- 130 people
- Sponsor
- Assiut University
Gastric Atrophy
Gastrin, Anti-helicobacter Pylori and Pepsinogen Diagnostic Accuracy Study
This research study is taking place to find out if a simple blood test can diagnose inflammation in the stomach. Prolonged inflammation in the stomach can lead to Ulcers and even Cancer in the long run.
- Trial name
- GAP-DA (NCT07060482)
- Testing
- Panel of biomarkers including Gastrin 17, pepsinogen 1 and 2, and anti-helicobacter pylori antibodies.
- Volunteers
- 240 people
- Sponsor
- Royal College of Surgeons, Ireland