Clinical trials: Gender Differences
ADHD, Attention Deficit Hyperactivity Disorder
Adolescent Changes in Brain and Behavior in Boys and Girls With ADHD
The purpose of the study is to examine the developmental trajectory of response control in boys and girls with ADHD entering adolescence.
- Trial name
- NCT05927506
- Testing
- Other
- Where
- United States
- Volunteers
- 312 people, healthy volunteers welcome
- Sponsor
- Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
Nicotine
Nicotine and Brain Imaging Research Study
The aim of this study is to assess the impact of smoking on cortical GABA levels in males and females. Using magnetic resonance spectroscopy (MRS), we will examine the impact of sex and menstrual cycle phase on brain…
- Trial name
- NCT01227343
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Thrombosis, Exercise Training
The Effect of Team Sports on the Risk of Thrombosis in Elderly Individuals in a Municipality Setting (TEAM-AGE)
Cardiovascular disease, and especially myocardial infarction, is the most common cause of death globally, and is particularly common in older individuals.
- Conditions
- Thrombosis, Exercise Training, Sex Differences
- Trial name
- TEAM-AGE (NCT04611191)
- Testing
- Team Sports, Control
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Abdominal Aortic Aneurysm, Abdominal Aortic Aneurysm Without Rupture
Elective Treatment Rates and Surgical Non-eligibility Among Men and Women With Intact Abdominal Aortic Aneurysms
The overall aim is to determine the frequency by which women and men with intact abdominal aortic aneurysms (AAA) are treated with elective surgery at three vascular outpatient clinics in Europe, and to investigate whether the…
- Conditions
- Abdominal Aortic Aneurysm, Abdominal Aortic Aneurysm Without Rupture, Aneurysm, Aortic Aneurysm
- Trial name
- NCT05346289
- Testing
- Elective surgery for intact AAA
- Where
- Sweden
- Volunteers
- 400 people
- Sponsor
- Karolinska University Hospital
Healthy
Influence of Meal Schedule: Gender Differences
Gender differences in the effect of meal schedule will be studied in a parallel design (10 women and 10 men). In two separate days a probe meal (290 stewed beans, 35 g bread, 100 mL water; 549 Kcal) will be administered in the…
- Trial name
- NCT03773432
- Testing
- Probe meal
- Where
- Spain
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Meningococcal Meningitis, Serogroup B, Transgender Persons
Investigating Gender and Sex Differences in Immune Responses Through Vaccination of Transgender and Cisgender Persons
Sexual differences are a well-established source of biological variation in immune system functioning, with men often displaying lower adaptive immune responses (e.g.
- Conditions
- Meningococcal Meningitis, Serogroup B, Transgender Persons, Sex Differences in Immune Response, Vaccination
- Trial name
- Vaxxygender (NCT06832514)
- Testing
- Serogroup B meningococal vaccine
- Where
- Belgium
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University Ghent
Acute Myocardial Infarction
Sex Differences in Relative Survival and Excess Mortality Following Acute Myocardial Infarction
The aim of this study was to estimate the impact of sex on relative survival and excess mortality following acute myocardial infarction (AMI) using a population-based cohort within a relative survival framework.
- Trial name
- NCT02952417
- Testing
- Excess mortality
- Volunteers
- 180,000 people
- Sponsor
- University of Leeds
Cannabis Use Disorder
Endocannabinoids in Reward
This study will examine sex differences in the effects of cannabis in people that regularly use it. Men and women that use cannabis at least 4 days a week will participate in a study involving 3 in-person visits.
- Trial name
- NCT07815691
- Testing
- Dronabinol
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- Medical University of South Carolina
ACL Tear
Psychological Factors Influencing the Patient-reported and Functional Outcome of ACL Reconstruction and Their Sex-specific Differences
Psychological parameters among patients undergoing ACL reconstruction and their impact on the patient-reported and functional outcome of reconstruction will be prospectively evaluated
- Trial name
- NCT06156501
- Testing
- ACL Reconstruction
- Where
- Austria
- Volunteers
- 100 people
- Sponsor
- Medical University of Vienna
Cancer
Mindfulness-Based Art Therapy for Cancer Patients
The purpose of this study is to determine whether cancer patients who receive the mindfulness-based art therapy (MBAT) program demonstrate improvement in health-related quality of life, a reduction in stress-related symptoms, and…
- Trial name
- NCT00034970
- Testing
- Mindfulness-based at therapy
- Where
- United States
- Volunteers
- 114 people
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
Hyperuricemia
Gender Differences in the Metabolic Effects of Uric Acid
Increased stiffening of the heart and blood vessels is a predictor of heart disease. Stiffening has been found to be greater in women than men, which puts women with poor blood sugar control at a greater risk for heart disease…
- Trial name
- NCT03076684
- Testing
- low-fructose diet, Allopurinol
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Glucose Metabolism Disorders
Relative Contribution of Brain Insulin Action for Postprandial Metabolism
The goal of this clinical trial is to clarify (i) the contribution of brain insulin action on regulation of systemic metabolism, (ii) sex-specific differences in the central regulation and (iii) the influence of the menstrual…
- Trial name
- BrainInsPPM (NCT06295640)
- Testing
- Oral glucose tolerance test with double-tracer dilution and intranasal insulin spray
- Where
- Germany
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University of Ulm
Cannabis
Gender Related Differences in the Acute Effects of Delta-9-Tetrahydrocannabinol in Healthy Humans: Sub-Study II
The purpose of the study is to characterize the acute effects of cannabinoids in women relative to men and to begin probing the mechanisms that may underlie gender differences.
- Trial name
- THC-Gender-II (NCT04704271)
- Testing
- Inhaled THC
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Yale University
Sexual Dimorphism, Cone-beam Computed Tomography
Sexual Dimorphism of Sphenoid and Maxillary Air Sinuses Via 3D Volumetric Segmentation of CBCT
Sexual dimorphism from skeletal remains a crucial step towards biological profile reconstruction since these are some of the last structures to remain after death.
- Conditions
- Sexual Dimorphism, Cone-beam Computed Tomography, Maxillary Sinus, Sphenoid Sinus
- Trial name
- NCT05907083
- Testing
- cone beam computer tomography
- Volunteers
- 204 people
- Sponsor
- Cairo University
IBS - Irritable Bowel Syndrome
Sex Differences in Effectiveness of CBT on IBS Project 3
Cognitive Behavioral Therapy (CBT) is the most well researched and most effective treatment for IBS targeting the brain-gut-microbiome (BGM) axis, and preliminary data show that this therapeutic effect is associated with a…
- Trial name
- U54_P3_CBT (NCT05155631)
- Testing
- COGNITIVE BEHAVIORAL THERAPY
- Where
- United States
- Volunteers
- 92 people
- Sponsor
- University of California, Los Angeles
Fatigue
Fatigability and Cognitive Demand With Aging
This study will determine the influence of a cognitive task performed during fatiguing contractions.
- Trial name
- NCT05121272
- Testing
- cognitive task
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Pacemaker, Artificial, Cohort Studies
Morbidity, Mortality and Gender Differences in Patients With Pacemakers
Previous publications suggest gender difference in outcome parameters after pacemaker implantation. Aim of this study is to investigate gender differences in patients with pacemaker.
- Conditions
- Pacemaker, Artificial, Cohort Studies, Arrhythmias Requiring Therapy, Cardiac Pacing, Artificial
- Trial name
- NCT03388281
- Testing
- No intervention, retrospective analysis only.
- Volunteers
- 11,444 people
- Sponsor
- Medical University of Vienna
Red Blood Cell Transfusions, Sex Differences
Effects of Donor-recipient Sex-matched Blood Transfusion on Patient Outcomes
Red blood cell (RBC) transfusions are selected based upon matching donor and recipient blood group: donor and recipient sex are not considered when selecting blood for transfusion.
- Conditions
- Red Blood Cell Transfusions, Sex Differences, Health Services, Critically Ill Intensive Care Unit Patients
- Trial name
- SexMATTERS RCT (NCT06840756)
- Testing
- Sex-mismatched red blood cell transfusions, Sex-matched red blood cell transfusions
- Where
- 8 sites in Canada
- Volunteers
- 11,082 people
- Sponsor
- Michelle Zeller
Carotid Stenosis
Differences of the Postoperative Outcome for Carotid Surgery Patients Treated by Either Male or Female Surgeons
This research will focus on the differences of the postoperative outcome for carotid surgery patients treated by either male or female surgeons.
- Trial name
- NCT06485102
- Testing
- Carotid Surgery in patients with symptomatic or asymptomatic stenosis
- Where
- Germany
- Volunteers
- 800 people
- Sponsor
- University Hospital Augsburg
Vasodilation, Hypoxia
Sex-related Differences in Sympathetic Vascular Transduction in the Setting of Hypoxemia
The purpose of this project is to identify sex-related differences in the effect of hypoxia on sympathetic vascular transduction.
- Trial name
- NCT05256069
- Testing
- Propranolol Pill
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia