Clinical trials: Gender Differences
Volleyball Player
An Investigation of Kinesiophobia in Volleyball Players, With a Focus on Sex-Based Differences
Kinesiophobia is a form of behavior that includes fear and anxiety in which the person tends to stay away from the movement. . In the future, this may lead to a decrease in muscle strength and condition, leading to loss or…
- Trial name
- NCT05795426
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital
Non-Specific Chronic Low-back Pain
Influence of Gender Difference on Knee Proprioception in Non-Specific Low Back Pain Among Young Adults
the aim of the study is to investigate the impact of gender difference on knee proprioception among non specific low back pain young adults.
- Trial name
- NCT06716515
- Testing
- digital inclinometer
- Volunteers
- 82 people
- Sponsor
- Cairo University
Back Pain
Pain Assessment and Quality of Life in Back Pain Patients: Role of Milnacipran
1. To show that patients with greater pain sensitivity will show greater improvement in their symptoms (self-reported pain intensity, mood, sleep, and quality of life) than those with lower pain sensitivity, based on QST, after…
- Trial name
- NCT01221740
- Testing
- Savella
- Where
- United States
- Sponsor
- Brigham and Women's Hospital
Gender Role Disorder, Male to Female Type
Gender-specific aEEGs and Outcome in Preterms
Background and objectives: Male sex is a risk factor for poor neurodevelopmental outcome following preterm birth. The investigators aimed to investigate gender-related differences in amplitude-integrated electroencephalography…
- Trial name
- NCT01562236
- Where
- Austria
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Nicotine Dependence
Gender Differences in Response to Nicotine Replacement Therapy and De-Nicotinized Cigarettes
This study will investigate the underlying neurobiology of differences between male and female smokers. Research suggests that women are less responsive to nicotine replacement therapy (NRT) than men and more responsive to the…
- Trial name
- BIRCWH (NCT00960778)
- Testing
- nicotine patch (Nicoderm Committed Quitter (CQ), Habitrol), denicotinized cigarettes (Quest 3 cigarettes)
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Medical University of South Carolina
Obesity
Direct Measurement of Ingestive Behaviour in Relation to Sex Differences and Gastrointestinal Hormone Levels in Patients After Metabolic and Bariatric Surgery
Bariatric surgery (BS), especially procedures like Sleeve Gastrectomy (SG) and Roux-en-Y gastric bypass (RYGB), is the most effective treatment for obesity.
- Trial name
- DIBASH (NCT06538948)
- Testing
- Bariatric Surgery
- Where
- 2 sites in Switzerland
- Volunteers
- 420 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Healthy Participants
The UBC Long-distance Triathlon Adaptation Study
The purpose of this study is to investigate the effect of 12-months of individualized endurance-training (swimming, cycling and running) on physiological and psychological adaptations in exercise naïve individuals.
- Trial name
- ULTRA (NCT06467656)
- Testing
- Individualized, periodized endurance training for ultra-endurance triathlon., Time-Aligned Control
- Where
- Canada
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Alcohol Use Disorder
Sex Differences in Trauma, Inflammation and Brain Function and the Implications for Treatment Efficacy in Alcohol Use Disorder
The goal of this clinical trial is to identify sex-specific biomarkers that confer greater susceptibility for Alcohol Use Disorder (AUD) and differentiate how treatment response varies by sex in people with Alcohol Use Disorder.
- Trial name
- ABSTAIN (NCT06426303)
- Testing
- Naltrexone
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Milky Kohno
Heart Failure With Preserved Ejection Fraction
Study to Evaluate Sex Differences in the Acute Effects of PL-3994 in Heart Failure Subjects
A Multi-Center, Unblinded, Single-Arm Study to Evaluate Sex Differences in the Acute Effects of PL-3994 on Myocardial cGMP Enhancement and Hemodynamics in Heart Failure with Preserved Ejection Fraction
- Trial name
- NCT04318145
- Testing
- PL-3994 Aqueous Intravenous Solution Dose Ascention, PL-3994 Aqueous Intravenous Solution Single Dose
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Palatin Technologies, Inc
Sex Difference, Virtual Care
VR Learning Program for Sexual-and-gender-diversity Care
The study is designed to create a VR learning program for sexual-and-gender-diversity care and compare the short-term and long-term effects on caring behaviors in nursing students.
- Conditions
- Sex Difference, Virtual Care, Nursing Care
- Trial name
- NCT07535216
- Testing
- VR learning program for SGD care
- Where
- Taiwan
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- National Yang Ming Chiao Tung University Hospital
Metabolic Syndrome, Dietary Diversity
Gender Difference of Metabolic Syndrome and Its Association Between Dietary Diversity at Different Ages
With the development of economics in China, the dietary diversity got higher. Meanwhile, the prevalence of metabolic syndrome (MetS) raised up as well.
- Conditions
- Metabolic Syndrome, Dietary Diversity, Age
- Trial name
- NCT03237598
- Volunteers
- 4,308 people
- Sponsor
- Nanjing Medical University
Stress
Differences by Sex and Genotype in the Effects of Stress on Executive Functions
The aim of this project is to test the effects of an environmental factor (mild stress) on prefrontal cortex (PFC) and the cognitive functions that depend on PFC (collectively called executive functions [EFs]), and to test our…
- Trial name
- NCT04273880
- Testing
- Methylphenidate, Vitamin C
- Where
- Canada
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Elderly, Chronic Pain
Characterization of Chronic Pain in Elderly Population With Emphasis on Differences Between Gender
Introduction: It is estimated that by 2025 there will be approximately 1.2 billion people above 60 years old. Global projections indicate that by 2050 there will be about 2 billion elders, 80% of them living in developing…
- Conditions
- Elderly, Chronic Pain, Gender
- Trial name
- NCT06855797
- Testing
- Observation
- Where
- Brazil
- Volunteers
- 474 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Healthy
Gender Difference in Response to Caffeine in Children and Adolescents
Caffeine use is on the rise in America, and one of the most popular sources is soda. Among youth ages 8-16, caffeine consumption has increased by over 70% in the past 30 years.
- Trial name
- NCT02119416
- Testing
- Low Caffeine Administration first (1mg/kg body weight), High Caffeine Administration first (2mg/kg body weight)
- Where
- United States
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- State University of New York at Buffalo
Generalized Anxiety Disorder
MBSR Mechanisms in GAD
The purpose of this study is to understand the neural mechanisms that drive response to MBSR compared to stress education in patients with generalized anxiety disorder (GAD), and to examine the degree to which sex differences in…
- Trial name
- NCT05064813
- Testing
- Mindfulness Based Stress Reduction MBSR Intervention, Stress Education Control Condition (SE)
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- NYU Langone Health
HIV Infections
Kaletra Sex/Gender Pharmacokinetics (PK) Study
The levels of lopinavir achieved in the blood following oral ingestion of standard doses of Kaletra (lopinavir/ritonavir) in HIV-infected men was compared with those achieved in HIV-infected women receiving the same dose of the…
- Trial name
- LPVGenderPK (NCT00148759)
- Testing
- LPV/r
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Emory University
Peripheral Artery Disease, Intermittent Claudication
Exercise in Peripheral Artery Disease
This research project aims to investigate the gender-based difference in patients with peripheral artery disease. To attend this, this study has two specific objectives: Objective 1: To identify gender-specific barriers towards…
- Trial name
- GrEnADa (NCT02878954)
- Testing
- No intervention (Observational study), Control session, Exercise session
- Volunteers
- 160 people
- Sponsor
- KU Leuven
Glycemic Control, Insulin Sensitivity
Comparing the Effects of Different Types of Exercise on Glucose Handling
The purpose of the proposed study is to compare the acute effects of different types of exercise modalities on glucose handling in young, healthy males and females.
- Conditions
- Glycemic Control, Insulin Sensitivity, Sex Differences
- Trial name
- NCT06217679
- Testing
- Control Oral Glucose Tolerance Test, Mixed Exercise
- Where
- Canada
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Waterloo
Obstructive Sleep Apnea
Obstructive Sleep Apnea Among Somali-Americans
The investigators seek to advance the understanding of obstructive sleep apnea as it relates to different ethnic origins as well as sex differences.
- Trial name
- Somali OSA (NCT04124848)
- Where
- United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Congenital Heart Disease, Heart Failure
Gender Difference in NET Activation in Patients With Congenital Heart Disease and Heart Failure
Neutrophil hyperactivation has detrimental effects on cardiac tissue after injuries, leading to fibrosis lesions and cardiac dysfunction.
- Conditions
- Congenital Heart Disease, Heart Failure, Gender
- Trial name
- FIBRONETx (NCT05263843)
- Testing
- Biological markers of myocardial fibrosis
- Where
- 2 sites in France
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris