Clinical trials: Gender Identity
Gender Dysphoria, Gender Identity Disorder
TransCare - Genital Surgery for Trans Women in Centralized vs. Decentralized Health Care Delivery Settings
Trans (i.e., transgender, transsexual) individuals experience a gender that does not match their sex assigned at birth (Gender Incongruence), which can lead to distress called gender dysphoria (formerly known as transsexualism).
- Conditions
- Gender Dysphoria, Gender Identity Disorder, Transsexualism, Gender Identity
- Trial name
- NCT03872648
- Where
- Germany
- Volunteers
- 64 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Pain Catastrophizing, Pain, Chronic
Efficacy of a Chronic Pain Treatment Prior to Gender-affirming Surgery
The primary objective of this study is to examine a single-session, 2-hour group intervention provided to a population of transgender or gender-diverse patients with chronic pain prior to gender-affirming surgery, to determine if…
- Conditions
- Pain Catastrophizing, Pain, Chronic, Gender Identity
- Trial name
- NCT06443164
- Testing
- Empowered Relief, Standard of Care
- Where
- United States
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Alcohol Use Disorder
Improving Alcohol Use Disorder Treatment for Gender Minority Populations
Gender minority (GM; transgender and gender non-conforming) individuals experience disproportionately high rates of hazardous drinking and alcohol use disorder (AUD) and are an NIH-designated disparity population (NOT-MD-19-001).
- Trial name
- NCT05070793
- Testing
- Culturally adapted interpersonal psychotherapy
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- New York State Psychiatric Institute
Sexual Orientation, Gender Identity
Increasing Effective Mental Health Care for LGBT Clients
The overall aims of the 5-year University of Maryland Prevention Research Center (UMD-PRC) Core Research Project are to identify, refine, implement, evaluate, translate, disseminate, and communicate approaches and tools that can…
- Trial name
- UMD-PRC (NCT05352659)
- Testing
- Face-to-face and online LGBTQ+ training, On-line training
- Where
- United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University of Maryland, College Park
LGBT Health, Cultural Competency
Comparative Effectiveness Research to Improve the Health of Sexual and Gender Minority Patients Through Cultural Competence and Skill Training of Community Health Center Providers and Non-clinical Staff
The primary goal of this PCORI proposal is to evaluate the impact of enhanced provider and clinical staff training to address the health disparities of SGM CHC patients to ultimately improve their health outcomes because CHCs are…
- Conditions
- LGBT Health, Cultural Competency, Education, Sexual Orientation
- Trial name
- PCORI-SOGI (NCT03554785)
- Testing
- Clinician and Non-clinician staff training
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Fenway Community Health
Headache, Gender Identity
Effect of Hormones on Frequency of Headache and Brain Structure and Function in Puberty
With a rising population of transgender adults and youth, there is a need for more research to meet the needs of this community.
- Trial name
- NCT05607303
- Testing
- Clinical estrogen therapy
- Where
- United States
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Gender Identity Disorder of Adult, Voiding Disorders
Transgender Post-reassignment Urogynecologic Measures and Perceptions
The intent of this mixed methods study for transgender women after gender confirmation surgery is to characterize and subsequently create a validated screening questionnaire for postoperative urologic and pelvic floor symptoms.
- Conditions
- Gender Identity Disorder of Adult, Voiding Disorders, Sexual Dysfunction
- Trial name
- NCT03293771
- Testing
- Focus group interviews, Questionnaire packet
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Transgenderism, Stigma, Social
Supporting Trans Identities and Occupational Justice Through Narrative Informed Theatre: Supporting Trans Identities and Occupational Justice Through Narrative Informed Theatre
Importance: Societal stigma gravely impedes occupational justice for trans individuals, producing vast health disparities for this population.
- Trial name
- NCT04515654
- Testing
- IDEAS (Identity Evolution and Sharing) Performance
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Indiana University
Gender Dysphoria
Gender Identity and Own Body Perception
This study will provide valuable information on the neurobiological underpinning of gender dysphoria (GD) and the effects of sex hormones, and promises to uncover functional or structural neural patterns that could predict…
- Trial name
- NCT04374708
- Testing
- fMRI
- Where
- United States
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Hypogonadism, Gender Identity Dysphoria
The Effect of Sex Steroid Replacement Therapy in the Hypogonadism and Transgender Active-Duty Population
It has been known that both estrogen and testosterone are the major sex steroids regulating bone metabolism and other physiological changes in both male and female, respectively.
- Trial name
- NCT06247267
- Testing
- Fortesta, Estradiol
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Walter Reed National Military Medical Center
Transgender Persons, Health Services for Transgender Persons
THE GUIDE: Transforming Health for Young Adults Using Interventions to Drive Engagement
This is a randomized controlled trial to test the effectiveness of an interactive educational app-based digital intervention that provides knowledge and support to transgender and gender-diverse (TGD) young adults ages 18-29…
- Conditions
- Transgender Persons, Health Services for Transgender Persons, Gender Identity
- Trial name
- NCT06177600
- Testing
- Interactive educational digital platform for transgender and gender-diverse (TGD) young adults and caregivers
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Gender Identity
Sexual Dimorphism Analysis in Egyptian Population by Locating the Mandibular Canal Using CBCT
Sexual dimorphism analysis in Egyptian population by locating the mandibular canal using cone-beam computed tomography: an observational cross sectional study
- Trial name
- NCT03175445
- Testing
- CBCT scan by planmeca promax
- Where
- Egypt
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- Cairo University
Gender Dysphoria, Gender Identity Disorder
Sexuality in Transmen During Hormone and Operative Treatment
With this analysis the investigators aim at discovering a difference in sexuality between transmen, cissexual women and cissexual men. A potential impact of body satisfaction will also be explored.
- Conditions
- Gender Dysphoria, Gender Identity Disorder, Transsexualism, Body Image
- Trial name
- Transmann (NCT03637920)
- Where
- Austria
- Volunteers
- 160 people
- Sponsor
- Medical University of Graz
Transsexualism
Testosterone and Its Metabolites in GID
The purposes of this study are: to determine the role of testosterone versus dihydrotestosterone with respect to the following physiological functions: bone metabolism, body composition, insulin resistance and lipid profile to…
- Trial name
- NCT00146146
- Testing
- testosterone undecanoate alone, testosterone undecanoate plus letrozole, testosterone undecanoate plus dutasteride
- Where
- Italy
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Unita Complessa di Ostetricia e Ginecologia
Gender Dysphoria
The Relation of GnRH Treatment to QTc Interval in Transgender Females
Background: The QT interval of the electrocardiogram (ECG), corrected for heart rate (QTc), is a measure of the duration of ventricular repolarization and is a widely used marker of ventricular arrhythmia risk.
- Trial name
- NCT03078829
- Testing
- Treatment with a GnRh agonists
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- University of California, San Francisco
Pain, Gender Identity
State of Hormones Impact Nociceptive Expression
The Investigators have recently published on differences in pain sensitivity measures between cis and trans individuals in the local area.
- Trial name
- SHINE (NCT05787470)
- Testing
- Quantative sensory testing, Blood Draw
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Mental Health Wellness 1, Sexual Orientation
Sexual and Gender Minority Emerging Adults Eliciting Narratives
Critical narrative interventions (CNIs) have not been examined for addressing psychological outcomes (e.g., depression, anxiety, self-esteem, empowerment, psychological well-being) within sexual and gender minority emerging…
- Conditions
- Mental Health Wellness 1, Sexual Orientation, Gender Identity
- Trial name
- SEEN (NCT05899218)
- Testing
- Critical Narrative Development
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Gender Dysphoria, Adult
Comparative Study of Gender Identity Disorder Versus Control
Gender dysphoria is manifested by an internal tension between biological sex and gender, that is, by a non-congruence, in the subjects who suffer from it, between their sex of birth and their social gender identity.
- Trial name
- TRANSIDENT (NCT04935164)
- Testing
- Psychiatric evaluations
- Where
- France
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Henri Laborit
Mental Health
Empowering Newcomer Voices: A Trauma-Informed, Gender-Responsive Group Intervention in Schools (VOCES-NUEVAS)
The goal of this study is to see if VOCES-NUEVAS, a school-based program for newcomer girls from Latin America, is helpful and easy to use.
- Trial name
- VOCES-NUEVAS (NCT07041931)
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Sexual and Gender Minorities, Hospice
Intervention to Collect and Utilize Sexual Orientation and Gender Identity (SOGI) Information in Hospice
Older sexual and gender minority (SGM) patients are at risk for receiving inequitable end-of-life care; those with Alzheimer's disease and related dementias (ADRD) are at particularly high risk.
- Conditions
- Sexual and Gender Minorities, Hospice, Alzheimer's Disease and Related Dementias
- Trial name
- NCT05877391
- Testing
- SGM Communication Intervention
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver