Clinical trials: Gender Role
Menstrual Cycle, Hormonal Contraception
Oxytocin and Reward Processing in Women
Oxytocin is a hypothalamic neuropeptide that is best known for its peripheral physiological effects in the female organism i.e., uterine contractions during birth.
- Trial name
- NCT06222749
- Testing
- Intranasal oxytocin administration
- Where
- Germany
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- International Research Training Group 2804
Nursing Role
Combating Violence Against Women
The aim of the study was to investigate the effect of the program to combat violence against women on domestic violence awareness and gender role attitudes.
- Trial name
- NCT07049510
- Testing
- Experimental: Experimental: Combating violence against women
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Hitit University
Surgery
Tranexamic Acid in Gender Mastectomy
The goal of this study is to examine the use of tranexamic acid (TXA) in gender mastectomy surgery, specifically looking at volume loss (blood and transudate) postoperatively.
- Trial name
- NCT04372940
- Testing
- Tranexamic Acid Irrigation, Saline Irrigation
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Intimate Partner Violence (IPV), Well-being/Quality of Life
Impacts of the Indashyikirwa Program on Intimate Partner Violence in Syria
This study aims to evaluate the effectiveness of the Indashyikirwa program in enhancing women's empowerment and reducing Intimate Partner Violence (IPV) in conflict-affected communities in Northeast Syria.
- Conditions
- Intimate Partner Violence (IPV), Well-being/Quality of Life, Decision Making, Gender-Based Violence
- Trial name
- NCT06735417
- Testing
- Indashyikirwa program
- Where
- Syria
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- International Security and Development Center gGmbH
Cardiovascular
The Role of EDHFs on Blood Pressure Following a Bout of Prolonged Sitting
Canadians spend most of their day in sedentary postures (i.e., sitting, lying, reclining). While the beneficial impacts of physical activity on the heart are well-established, less is known about the consequences during time…
- Trial name
- NCT07396857
- Testing
- Fluconazole 150 mg
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Université de Sherbrooke
Stress, Early Life Stress
How Does the Opioid System Shape Stress and Social Behaviour in Men and Women and What Role Does Childhood Unpredictability Play?
The study aims to investigate sex differences in the effect of mu-opioid receptor (MOR) activation on stress response and social behaviour modulated by early life stress.
- Conditions
- Stress, Early Life Stress, Sex Differences, Opioid
- Trial name
- MOR-SAFE (NCT07778511)
- Testing
- Morphine
- Where
- Switzerland
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Sara L. Kroll
Major Depressive Disorder, Perinatal Depression
The Role of Sex Steroids and Serotonin Brain Dynamics in Perinatal Mental Health
Hormonal transitions such as across pregnancy and postpartum may trigger depressive episodes in some women. It is not known why, but estrogen sensitivity may play a critical role.
- Trial name
- NCT03795688
- Testing
- Pregnancy
- Where
- Denmark
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Vibe G Frøkjær, MD, PhD
Gender Role Disorder, Male to Female Type
Gender-specific aEEGs and Outcome in Preterms
Background and objectives: Male sex is a risk factor for poor neurodevelopmental outcome following preterm birth. The investigators aimed to investigate gender-related differences in amplitude-integrated electroencephalography…
- Trial name
- NCT01562236
- Where
- Austria
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Interoception, Perceived Stress
Interoceptive Awareness, Perceived Stress, and Physical Performance in Sport Sciences Students
This cross-sectional observational study examined the relationships between interoceptive awareness, perceived stress, state and trait anxiety, sleep quality, and physical performance indicators in university-level sport sciences…
- Conditions
- Interoception, Perceived Stress, Anxiety, Sleep Quality
- Trial name
- NCT07696234
- Testing
- Psychological and Physical Performance Assessment Battery
- Where
- Turkey (Türkiye)
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Inonu University
Hypertrophy, Physiologic Hypertrophy
Beta2-adrenergic Agonism and Muscle Remodelling
The study aims to investigate gender-specific adaptations to beta2-adrenoceptor stimulation with selective short- and long-acting beta2-agonist with emphasis on skeletal muscle in relation to performance enhancing effects and…
- Conditions
- Hypertrophy, Physiologic Hypertrophy, Physical Activity
- Trial name
- NCT03565302
- Testing
- Formoterol, Terbutaline
- Where
- Denmark
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Morten Hostrup, PhD
Role of Sex Hormones Along the Neuromechanical Axis
Exploring the Modulatory Role of Sex Hormones Along the Neuromechanical Axis in Females
The goal of this project is to test our central hypothesis that changes in sex hormone concentration result in changes to the basic elements of motor control - at multiple levels, from the musculotendinous unit to motor control…
- Trial name
- EMRSHN (NCT03947684)
- Where
- United States
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Oxytocin, Estrogen
Dissecting the Role of Estradiol in Mediating Gender-specific Anxiolytic and Prosocial Effects of Oxytocin
The study aims to examine a behavioral and neural framework for understanding the sex-specific effects of the neuropeptide oxytocin (OXT).
- Conditions
- Oxytocin, Estrogen, Fear Extinction, Emotion Processing
- Trial name
- ESMory (NCT04330677)
- Testing
- Oxytocin nasal spray, Estrogen Gel
- Where
- Germany
- Volunteers
- 487 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bonn
Contraceptive Behavior, Social Norms
Impact of Gender-Transformative Interventions on Contraceptive Use and Reproductive Autonomy in Somalia
Since 2019, the International Rescue Committee (IRC) has led family planning programming in Somalia under the Women's Integrated Sexual Health (WISH) program, funded by the United Kingdom's Foreign, Commonwealth and Development…
- Trial name
- FPIL-SOM (NCT07902700)
- Testing
- Intensive Gender-Transformative Programming, Light-Touch Gender-Transformative Programming, Standard Family Planning Services (WISH-2)
- Where
- Somalia
- Volunteers
- 5,436 people, healthy volunteers welcome
- Sponsor
- Guttmacher Institute
Inflammatory Response
Examining the Role of Female Endogenous Sex Hormones in Eccentric Exercise
The fluctuating concentrations of female sex hormones, namely estrogen and progesterone may have an effect on the ability of the tissue to withstand challenging exercise conditions, such as eccentric exercise.
- Trial name
- NCT05934708
- Testing
- Eccentric leg extension
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Nurse's Role, Gender
Building Your Successful Nursing Career
This study aims to evaluate a career planning mobile App specifically tailored for male nurses.This three-year experimental project aims to recruit 120 male nurses (60）in the experimental group and 60 in the control group).
- Conditions
- Nurse's Role, Gender, Professional Burnout
- Trial name
- NCT06519643
- Testing
- career planning application
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Abuse Neglect, Social; Deprivation, Maltreatment Syndrome (Infant or Child)
Role of Psychoanalysis in Prevention of Girl Child Maltreatment and Neglect
In India, precisely northern states, skewed sex ratios, female feticide and higher child mortality rates for girls have become serious concern.
- Trial name
- NCT02116647
- Testing
- Psychoanalytic therapy
- Where
- 2 sites in India
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- Macmillan Research Group UK
Smoking Cessation
The Dads in Gear Program: An Innovative Men-centered Approach to Smoking Cessation
The purpose of this feasibility study is to evaluate Dads in Gear, a tailored program to support expectant and new fathers efforts to quit smoking.
- Trial name
- DIG (NCT03585634)
- Testing
- Dads in Gear Program
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Endometrial Cancer
Role of Biomarkers in Endometrial Cancer Recurrence in Samples From Patients With Stage II, Stage III, or Stage IV Endometrial Cancer
RATIONALE: Studying samples of blood and tissue from patients with cancer in the laboratory may help doctors identify and learn more about biomarkers related to cancer.
- Trial name
- NCT01150682
- Testing
- RNA analysis, reverse transcriptase-polymerase chain reaction, enzyme-linked immunosorbent assay
- Volunteers
- 865 people, healthy volunteers welcome
- Sponsor
- Gynecologic Oncology Group
Mastectomy, Gender Affirmation Surgery
The Role of Amnion Membrane Allografts in Nipple Preservation
The overall objective of this proposal is to conduct a randomized-controlled study to determine whether treatment with dehydrated human amnion/chorion membrane (dHACMs) allografts can improve NAC viability in patients undergoing…
- Conditions
- Mastectomy, Gender Affirmation Surgery, Nipple Sparing Mastectomy, Prophylactic Mastectomy
- Trial name
- AmnioFix (NCT06073808)
- Testing
- AmnioFix dehydrated Human Amnion/Chorion Membrane Allograft, Control Device
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Stanford University
Type 2 Diabetes Mellitus, Healthy
Cardiovascular Mechanisms of Exercise Intolerance in Diabetes and the Role of Sex
This study will define the relationship of cardiac, vascular function and skeletal muscle blood flow (individually and together) to cardiovascular exercise capacity in in men and women with and without type 2 diabetes (T2DM).
- Conditions
- Type 2 Diabetes Mellitus, Healthy, Overweight, Cardiovascular Risk Factor
- Trial name
- NCT03419195
- Testing
- Cardiovascular exercise training
- Where
- United States
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver