Clinical trials: General Anesthesia
Intra-abdominal Surgery, Anesthesia
Open Lung Protective Extubation Following General Anesthesia
Perioperative respiratory complications are a major source of morbidity and mortality. Postoperative atelectasis plays a central role in their development.
- Conditions
- Intra-abdominal Surgery, Anesthesia, Lung Injury, Ventilator-Induced Lung Injury
- Trial name
- OLEXT-3 (NCT06296173)
- Testing
- Protective "open-lung" extubation, Conventional extubation
- Where
- 5 sites in Canada
- Volunteers
- 270 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Anesthesia Techniques, Percutaneous Nephrolithotomy
Effects of Spinal vs General Anesthesia on Systemic Inflammation in PCNL
This observational study aims to compare the effects of spinal and general anesthesia on perioperative systemic inflammatory response in patients undergoing percutaneous nephrolithotomy (PCNL).
- Conditions
- Anesthesia Techniques, Percutaneous Nephrolithotomy, Systemic Inflammation
- Trial name
- PCNL-ANES-INF (NCT07326670)
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Elazıg Fethi Sekin Sehir Hastanesi
Obstetric Anaesthesia With Cardiac Complications
A Superior Anesthetic Technique for the Cesarean Section From a Hemodynamic Perspective.
Cesarean section operations are increasing in rates worldwide. A proper anesthetic technique is required to maintain the safety of both the mother and the fetus.
- Trial name
- NCT04989270
- Testing
- General Anesthesia, Regional Anesthesia
- Where
- Oman
- Volunteers
- 2,500 people
- Sponsor
- Sultan Qaboos University
Non-small Cell Lung Cancer
The Effect of Combined General/Regional Anesthesia on Cancer Recurrence in Patients Having Lung Cancer Resections
The primary hypothesis is that disease-free survival is improved in patients undergoing resection for tumor thought to be stage I-III primary non-small cell lung cancer in patients with combined general-epidural anesthesia \&…
- Trial name
- NCT02840227
- Testing
- General anesthesia with opioid analgesia, Combined general/epidural anesthesia
- Where
- China
- Sponsor
- The Cleveland Clinic
Thyroidectomy
Superficial, Cervical Block in Thyroid Surgery, a Randomized Controlled Trial
The study investigates the impact on post-operative pain of the superficial cervical block with bupivacaine combined with subcutaneous infiltration of the incisional area in thyroid surgery under general anesthesia.
- Trial name
- NCT00472446
- Testing
- bilateral superficial cervical block
- Where
- Switzerland
- Volunteers
- 183 people
- Sponsor
- Cantonal Hospital of St. Gallen
Preoxygenation
Verbal Breathing Coaching to Improve Preoxygenation and Extend Safe Apnea Time in Anesthesia
This study explores whether simply guiding patients to breathe slowly and calmly before anesthesia can help improve oxygen levels and keep them safe for longer during induction.
- Trial name
- NCT07565259
- Testing
- Verbal Breathing Coaching
- Where
- Saudi Arabia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Prince Sultan Military Medical City
General Anesthesia, Chronic Pain, Postoperative
Risk Factors for Chronic Postoperative Pain After Elective Nephrectomy
Chronic postoperative pain (CPP) is typically defined as pain persisting for 3 months or more after surgery[1]. CPP is a common and increasingly prevalent morbidity, leading to long-term psychological issues, reduced quality of…
- Conditions
- General Anesthesia, Chronic Pain, Postoperative, Acute Pain, Postoperative, Surgery
- Trial name
- NCT06673979
- Testing
- Numeric Rating Scale
- Where
- Turkey (Türkiye)
- Volunteers
- 204 people
- Sponsor
- Istanbul University - Cerrahpasa
Anesthesia General
Study of the Effect of the Supine Position at Brain Velocities in Noncerebro - Injured Patient
To evaluate the pulsatility index changes after setting supine position in non brain- injured patient under general anesthesia.
- Trial name
- D-Velocity (NCT02930096)
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Poitiers University Hospital
Obstructive Sleep Apnea, Arrhythmia
Evaluation of Sleep Apnea and Cardiac Rhythm Abnormalities After Surgery Under General Anesthesia
Higher risk of cardiac and respiratory post-operative events is observed in patients with unrecognised Obstructive Sleep Apnea (OSA).
- Trial name
- Etude3A (NCT02833662)
- Testing
- Measure of ODI and heart rhythm
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Anesthesia, General
A Study to Assess Indices of SNAP vs VISTA on Surgical Patients Undergoing General Anesthesia
Establish the range of index values for the SNAP II corresponding to each anesthetic state studied.
- Trial name
- Precision GA (NCT00829803)
- Testing
- SNAP monitor; Bispectral Index Monitor (BIS Monitor)
- Where
- 4 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Stryker Instruments
Laparotomy
Respiratory Effects of Perioperative Oxygen During General Anaesthesia
Aim: To investigate the effect of high intra- and postoperative oxygen concentration (80%, as opposed to normally 30%) on pulmonary gas exchange and other pulmonary complications after abdominal surgery.
- Trial name
- NCT00637936
- Testing
- Oxygen
- Volunteers
- 35 people
- Sponsor
- University of Copenhagen
Obesity, Morbid
EPO2-A: Evaluation of Pre-Oxygenation in Morbid Obesity: Effect of Position and Positive Pressure Ventilation
The risk of complication associated with airway in obese patient is important. The result of pre-oxygenation gives the clinician a prolonged non-hypoxic apnea time.
- Trial name
- EPO2-A (NCT02590406)
- Testing
- Beach chair (BC) and ZEEP, Reverse Trendelenburg and NIPPV
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- Laval University
General Anesthesia, Hemodynamics
Effect of Operating Room Noise on BIS and Hemodynamics Under General Anesthesia
This prospective observational study aims to evaluate the impact of operating room noise on bispectral index (BIS) and hemodynamic parameters in patients undergoing general anesthesia.
- Conditions
- General Anesthesia, Hemodynamics, Noise Exposure
- Trial name
- NCT07194707
- Testing
- Intraoperative Noise Monitoring
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Hypothermia; Anesthesia
Effect of 10 Minute-prewarming on Core Body Temperature During Gynecologic Laparoscopic Surgery Under General Anesthesia
Previous research has shown beneficial effects of prewarming on preventing inadvertent perioperative hypothermia (IPH). Warming the surface of the body before the induction of anesthesia can reduce the temperature difference…
- Trial name
- NCT04027842
- Testing
- Prewarming
- Where
- South Korea
- Volunteers
- 54 people
- Sponsor
- Daegu Catholic University Medical Center
Anesthesia, General
Comparison of Spontaneous Ventilation Time in Air Without Desaturation After Positive Pressure Extubation Versus Aspiration Extubation When Awakening From General Anesthesia
The primary objective is to show that positive pressure extubation improves oxygenation immediately after extubation compared to extubation via "aspiration" by evaluating and comparing the onset time of desaturation during…
- Trial name
- NCT01323049
- Testing
- Positive pressure extubation, Aspiration/suction extubation
- Where
- France
- Volunteers
- 68 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
General Anesthesia
Evaluation of CNAP During Anesthesia
The purpose of this study is to compare the non invasive measurement of arterial pressure (CNAP monitor) with the invasive measurement of arterial pressure (radial artery catheter) during induction and maintenance of general…
- Trial name
- CnapEval (NCT01032226)
- Where
- France
- Volunteers
- 45 people
- Sponsor
- Hopital Foch
Neurodegeneration, General Anesthesia
Neurodegeneration in Newborns After Anesthetics
The purpose of the study is to quantify biomarkers of neural damage in neonates exposed to varying levels of volatile anesthetic in utero.
- Trial name
- NCT03064607
- Testing
- Fluid collection
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of Pennsylvania
Urinary Retention, Uterine Prolapse
Does Spinal Anesthesia for Prolapse Surgery With Lead to Urinary Retention?
The purpose of the study is to compare the risk of being unable to urinate shortly after surgery, also called acute post-operative urinary retention (POUR) between spinal and general anesthesia in women who undergo outpatient…
- Trial name
- NCT02547155
- Testing
- Spinal anesthesia, General anesthesia
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Anesthesia, Local
General Anesthesia, Versus Axillary Block for Ambulatory Hand Surgery: Randomized Prospective Study
This study aims to compare between general anesthesia and axillary nerve block for ambulatory hand surgery regarding postoperative sleep pattern and efficacy.
- Trial name
- NCT04727515
- Testing
- fentanyl 2µg/kg intravenously and maintained with isoflurane, Axillary nerve Block
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Ain Shams University
Intraoperative Hypotension, Jugular Veins
Internal Jugular Vein Ultrasound and Acute Kidney Injury After Abdominal Surgery
This observational study aims to learn whether changes in the internal jugular vein during anesthesia induction can help predict low blood pressure and kidney injury after surgery. The main questions it aims to answer are: 1.
- Conditions
- Intraoperative Hypotension, Jugular Veins, Hypotension on Induction, General Anesthesia With Propofol
- Trial name
- PRO-JUGULAR (NCT07638306)
- Testing
- Internal Jugular Vein Ultrasound Assesment
- Where
- Romania
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Tîrgu Mureș Emergency Clinical County Hospital, Romania