Clinical trials: General Anesthetics
Obesity &Amp; Overweight, General Anesthetic
Postoperative Opioid Consumption in Gastric Sleeve Surgery
The study aimed to compare balanced anesthesia protocols using only opioids as analgesics during induction in gastric sleeve surgery with protocols using opioids and ketamine together in terms of anesthesia management, opioid…
- Conditions
- Obesity &Amp; Overweight, General Anesthetic, Ketamine
- Trial name
- POCiGSS (NCT07135154)
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people
- Sponsor
- Balikesir University
Hypotension, Anesthesia
Methohexital v Propofol as General Anesthetic in Patients on ACEIs or ARBs
Patient undergoing general anesthesia in elective surgery will be assigned to receive either methohexital or propofol general anesthesia.
- Trial name
- NCT02624050
- Testing
- Methohexital, Propofol
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
General Anesthesia, Propofol Target-controlled Infusion
Effects of Epidural Local Anesthetics on Propofol Induction
The investigators designed a prospective, randomized, placebo-controlled study to determine whether thoracic epidural anesthesia(TEA) with different local anesthetics has different influences on the propofol dose during induction.
- Conditions
- General Anesthesia, Propofol Target-controlled Infusion, Thoracic Epidural Anesthesia
- Trial name
- NCT02000973
- Testing
- Lidocaine, Bupivacaine, Ropivacaine
- Volunteers
- 80 people
- Sponsor
- First Hospital of China Medical University
Airway Complication of Anaesthesia, Healthy
The Effects of General Anesthetics on Upper Airway Collapsibility in Healthy Subjects
The investigators hypothesize that propofol, when compared to sevoflurane, causes the upper airway to collapse more easily and causes less activity in the tongue muscle.
- Trial name
- NCT01557920
- Testing
- Propofol, Sevoflurane
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Anesthesia
the Impact of Noise on Requirements of Anesthetics During General Anesthesia
The investigators hypothesize that the noise level in the operating theatre influences the patients' requirements of anesthetics.
- Trial name
- NCT02534285
- Testing
- hearing protection
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- Technische Universität Dresden
Minimal Flow Anesthesia, General Anaesthesia
Minimal Flow Anesthesia and Infection Risk
This study is being done to find out if the heat and moisture that build up during minimal flow anesthesia can lead to the growth of germs (microorganisms) inside the anesthesia equipment.
- Conditions
- Minimal Flow Anesthesia, General Anaesthesia, Inhalation Anesthesia, Infection Risk
- Trial name
- NCT07092046
- Testing
- Sevoflurane (Volatile Anesthetic), Propofol 1%, Remifentanil 2 MG
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Child
Correlation of Nasopharyngeal (NP) and Lower Oesophageal (LO) Temperatures in Ventilated Children
Children lose heat under general anaesthesia, thus temperature is routinely monitored during anaesthesia for all but the shortest cases, and active warming can be used to prevent hypothermia and its resulting complications.
- Trial name
- NCT02201628
- Testing
- Nasopharyngeal and oesophageal temperature probes
- Where
- United Kingdom
- Volunteers
- 59 people
- Sponsor
- Great Ormond Street Hospital for Children NHS Foundation Trust
Fluid Overload
Does Fluid Requirement Decrease With the Use of Pneumatic Compression Device on Lower Limbs
Impact of intraoperative use of pneumatic peristaltic compression device on hemodynamics vis a vis on fluid requirement during general anaesthesia and surgery.
- Trial name
- NCT03789474
- Testing
- HUNTLEIGH FLOWTRON ACS900
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- All India Institute of Medical Sciences, Rishikesh
Arrhythmia, Cardiac, Kidney Cancer
Cardiac Arrhythmias in Patients Undergoing Kidney Cancer Surgery Depending on the Anaesthesia Method
This study evaluates the incidence of cardiac arrhythmias during the perioperative period in patients undergoing open kidney cancer surgery in the lateral position.
- Conditions
- Arrhythmia, Cardiac, Kidney Cancer, Surgery, Anesthesia, Local
- Trial name
- NCT02988219
- Testing
- Bupivacaine-fentanyl, Holter ECG monitor, Open kidney cancer surgery
- Where
- Poland
- Volunteers
- 50 people
- Sponsor
- Medical University of Warsaw
Gastrointestinal Neoplasms
Cerebral Blood Flow During Propofol Anaesthesia
General anaesthesia often reduces blood pressure whereby blood flow to the brain and other vital organs may become insufficient. Thus, medicine is often administered during anaesthesia to maintain blood pressure.
- Trial name
- NCT02951273
- Testing
- Study of cerebral blood flow
- Where
- Denmark
- Volunteers
- 30 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Adverse Effect of Unspecified General Anesthetics
Comparison of ProSeal Laryngeal Mask Airway to Laryngeal Mask Airway Supreme
Laryngeal mask airway is a widely used device in routine anesthesia for airway management during surgery. It consists of a tube with an inflatable cuff that is inserted into the mouth after induction of general anesthesia.
- Trial name
- NCT00836095
- Testing
- Supreme Laryngeal mask airway, Proseal laryngeal mask airway
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- Milton S. Hershey Medical Center
Inguinal Hernia
A Multi-site Randomized Controlled Trial Comparing Regional and General Anesthesia for Effects on Neurodevelopmental Outcome and Apnea in Infants
The primary purpose of the GAS study is to determine whether different types of anesthesia (Regional versus General) given to 720 infants undergoing inguinal hernia repair results in equivalent neurodevelopmental outcomes.
- Trial name
- GAS (NCT00756600)
- Testing
- Regional Anesthesia, General Anesthesia
- Where
- 30 sites in United States, Australia and 5 more
- Volunteers
- 643 people
- Sponsor
- Boston Children's Hospital
Anaesthesia
General Anesthesia With Xenon in Inspiratory Concentrations of 50% and 70% and Total I.V. Anaesthesia.
The purpose of this study is to evaluate the quantity of propofol administered with Xenon in two inspiratory concentrations, to maintain comparable depth of anaesthesia during the maintenance period of general anaesthesia.
- Trial name
- NCT00919126
- Testing
- Xenon, Medical Air in Oxygen
- Where
- 6 sites in France, Germany and 1 more
- Volunteers
- 102 people
- Sponsor
- Air Liquide SA
Anesthetic Gas Consumption and Cost-Effectiveness
Comparison of Different Ventilator and Vaporizer Technologies to Study Economic and Environmental Implications
The purpose of this study is to test whether or not the use of a low volume ventilator in an anesthesia machine reduces anesthetic costs significantly as compared to other high volume machines.
- Trial name
- NCT04851314
- Testing
- ICU certified ventilator, Non-ICU certified ventilator
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- University of California, Irvine
Myocardial Ischemia
A Comparison of the Effects of Intraoperative Administration of Metoprolol or Esmolol on General Anesthetic Requirement
We will compare three study groups receiving metoprolol, esmolol, or placebo. Level of anesthesia will be titrated to achieve the same range of BIS value in all groups.
- Trial name
- NCT00756236
- Testing
- Metoprolol, Esmolol, P-Group
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Oklahoma
Gastrostomy
Transversus Abdominis Plane Block on Stress Response
This study evaluates the effect of transversus abdominis plane(TAP) block combined with general anesthesia on perioperative stress response in patients undergoing radical gastrectomy.
- Trial name
- NCT03035916
- Testing
- Transversus abdominis plane block, Epidural anesthesia, control
- Where
- China
- Volunteers
- 91 people
- Sponsor
- Jilin University