Clinical trials: General Anxiety Disorder
Emergency Surgical Procedures, Postoperative Pain
Postoperative Progressive Relaxation Exercises for Pain and Anxiety After Emergency Surgery
This randomized controlled trial investigated the effectiveness of postoperative progressive relaxation exercises (PRE) on pain, anxiety, and physiological parameters among adult patients undergoing emergency general surgery.
- Conditions
- Emergency Surgical Procedures, Postoperative Pain, Postoperative Anxiety
- Trial name
- PRE-ES (NCT07301073)
- Testing
- Progressive Relaxation Exercises (PRE)
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Agri Ibrahim Cecen University
Prenatal Anxiety, Generalized Anxiety
Willkommen Mutterglück: Online CBT for Pregnant and Postpartum Women With Depression and Anxiety
This intervention study aims to evaluate the effectivity of web-based cognitive therapy in reducing depression and anxiety in pregnant and postpartum women.
- Conditions
- Prenatal Anxiety, Generalized Anxiety, Postpartum Depression, Major Depressive Disorder
- Trial name
- NCT04183946
- Testing
- Online Cognitive Behavioural Therapy
- Where
- Switzerland
- Volunteers
- 300 people
- Sponsor
- University of Zurich
Anxiety Generalized, Breast Cancer Female
Anti-anxiety Biotics for Breast Cancer Survivors
Cancer survivors experience more rapid declines in health-related quality of life which include physical and psychological comorbidities, the latter of which may be subclinical and often overlooked by primary care providers.
- Trial name
- ABBCS (NCT04784182)
- Testing
- probiotic plus prebiotic supplement
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Auburn University
Generalized Anxiety
An Eight-week Study to Evaluate the Efficacy and Safety of 2 Doses of Saredutant in Patients With Generalized Anxiety Disorder
The primary objective is to evaluate the efficacy of two fixed doses (100 mg and 30 mg once daily) of saredutant compared to placebo in patients with generalized anxiety disorder.
- Trial name
- NCT00390533
- Testing
- Saredutant
- Where
- 2 sites in United States, Australia
- Volunteers
- 428 people
- Sponsor
- Sanofi
Anxiety
Therapeutic Communication Training of the Stretcher Bearers on the Patient Anxiety (STRESSCOM)
Anxiety is a form of psychic and/or physical discomfort caused by the feeling of the imminence of a danger. It is a frequent perioperative manifestation of patients.
- Trial name
- STRESSCOM (NCT03849976)
- Testing
- Therapeutic communication
- Where
- France
- Volunteers
- 130 people
- Sponsor
- Lille Catholic University
Stress, Anxiety
ACT for HIV-Positive Men
The purpose of the current study is to examine the feasibility and effectiveness of acceptance and commitment therapy, a specific form of cognitive-behavioral therapy, for treating general mental health concerns among…
- Conditions
- Stress, Anxiety, Mental Disorder, Distress-based Psychopathology
- Trial name
- ACT for HIV (NCT06625437)
- Testing
- Acceptance and commitment therapy
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- University of Alabama at Birmingham
Generalized Anxiety Disorder
A Phase 2a Efficacy, Safety, Tolerability, and PK Study of SYT-510 in Participants With Generalized Anxiety Disorder
This is a single dose study to investigate the efficacy, safety, tolerability and the PK, of SYT-510 in participants who meet diagnostic criteria of GAD.
- Trial name
- NCT07478744
- Testing
- SYT-510
- Where
- United Kingdom
- Volunteers
- 24 people
- Sponsor
- Synendos Therapeutics AG
Major Depressive Disorder, Generalized Anxiety Disorder
The Modular Protocol for Mental Health (MPMH)
Currently, our best psychological treatments for anxiety and mood disorders only focus on individual diagnoses. So, there are separate treatments for Panic Disorder, or Depressive Disorder, or Social Anxiety, etc.
- Conditions
- Major Depressive Disorder, Generalized Anxiety Disorder, Posttraumatic Stress Disorder, Social Anxiety Disorder
- Trial name
- MPMH (NCT03143634)
- Testing
- The Modular Protocol for Mental Health, Treatment-as-usual
- Where
- United Kingdom
- Volunteers
- 43 people
- Sponsor
- Medical Research Council Cognition and Brain Sciences Unit
Generalized Anxiety Disorder
Cognitive Behavior Treatment of Older Adults With Generalized Anxiety Disorder in Primary Care
The purpose of this study is to determine whether cognitive behavior treatment (CBT) can be delivered effectively by providers of different expertise levels in adults age 60 and older in a primary care setting.
- Trial name
- NCT00765219
- Testing
- CBT, Usual Care
- Where
- United States
- Volunteers
- 222 people
- Sponsor
- Baylor College of Medicine
Generalized Anxiety Disorder
Relapse-prevention Study With Lu AA21004 (Vortioxetine) in Patients With Generalized Anxiety Disorder
The study will evaluate the long-term maintenance of efficacy of Lu AA21004 in patients with Generalized Anxiety Disorder (GAD) who responded to acute treatment with Lu AA21004.
- Trial name
- NCT00788034
- Testing
- Lu AA21004
- Where
- 81 sites in Argentina, Chile and 9 more
- Volunteers
- 459 people
- Sponsor
- H. Lundbeck A/S
Obsessive-Compulsive Disorder, Generalized Anxiety Disorder
Memantine Treatment for Obsessive-compulsive Disorder and Generalized Anxiety Disorder
The objective of this study was to obtain preliminary open-label data on the efficacy and tolerability of memantine, an anti-glutamatergic medication with a unique pharmacodynamic profile, in individuals with OCD and individuals…
- Trial name
- NCT00674219
- Testing
- Memantine
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- University of California, Los Angeles
Generalized Anxiety Disorder, Social Phobia
Effectiveness of Six Sessions CBT for Adolescents With Emotional Problems in Community Clinics
Background: There is need for more effectiveness studies concerning treatment of emotional symptom problems indicating anxiety and depression in adolescents.
- Conditions
- Generalized Anxiety Disorder, Social Phobia, Agoraphobia, Depression
- Trial name
- SMART (NCT02150265)
- Testing
- SMART manual cognitive behavioral therapy
- Where
- Norway
- Volunteers
- 163 people
- Sponsor
- University of Tromso
Preoperative Anxiety, Preoperative Sedation
Determination of ED50 and ED95 With Clinical Efficacy of Intranasal Dexmedetomidine Combined With Esketamine for Preoperative Sedation in Pediatric General Anesthesia
For pediatric patients undergoing general anesthesia, poor anesthesia induction compliance often has adverse effects on individual behavior in the early postoperative period.
- Conditions
- Preoperative Anxiety, Preoperative Sedation, Children, Dexmedetomidine
- Trial name
- NCT06853431
- Testing
- dexmedetomidine, Esketamine
- Where
- 2 sites in China
- Volunteers
- 80 people
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Generalized Anxiety Disorder
Safety & Efficacy Study of Quetiapine Fumarate (SEROQUEL®) vs. Placebo in Generalized Anxiety Disorder
The purpose of this study is to demonstrate that quetiapine SR (SEROQUEL®) is efficacious and safe in the acute treatment of patients with Generalized Anxiety Disorder.
- Trial name
- TITANIUM (NCT00329264)
- Testing
- Quetiapine fumarate
- Where
- 58 sites in United States
- Volunteers
- 876 people
- Sponsor
- AstraZeneca
Generalized Anxiety Disorder
A Trial of the Efficacy and Safety of Fixed Doses of SEP-363856 in Adults With Generalized Anxiety Disorder
This is a global, phase 3, randomized, double-blind, parallel-group, 3-arm, placebo-controlled, multicenter study designed to compare the efficacy, safety, and tolerability of fixed doses of SEP-363856 (50 and 75 milligrams per…
- Trial name
- NCT07759128
- Testing
- SEP-363856
- Where
- 17 sites in United States
- Volunteers
- 576 people
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
Anxiety Disorders, Generalized Anxiety Disorder
Motivational Interviewing and Cognitive Behavioural Therapy for Generalized Anxiety Disorder
The current study examines whether change-readiness, and consequently treatment outcome, can be enhanced in Cognitive Behavioral Therapy (CBT) for severe Generalized Anxiety Disorder (GAD) by adding a brief course of Motivational…
- Trial name
- NCT01488799
- Testing
- Motivational Interviewing and Cognitive Behavioural Therapy
- Where
- 2 sites in Canada
- Volunteers
- 85 people
- Sponsor
- York University
Generalized Anxiety Disorder
Exercise Training for the Treatment of Generalized Anxiety Disorder
The purpose of this study is to compare the effects of 6 weeks of endurance or strength training and a wait list comparison condition on symptoms of Generalized Anxiety Disorder (GAD).
- Trial name
- NCT00953654
- Testing
- Strength Training, Endurance Training
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Georgia
Anxiety, Anxiety Acute
Anxiety Skills Study
The purposes of this study are: (1) to identify baseline predictors of relative success in cognitive, behavioral, and mindfulness-based treatments for anxiety, (2) explore who benefits from a brief, video-based skill training…
- Conditions
- Anxiety, Anxiety Acute, Anxiety Chronic, Anxiety and Mood Disorders
- Trial name
- NCT07774481
- Testing
- Cognitive therapy, Behavioral therapy, Mindfulness-based therapy
- Where
- United States
- Volunteers
- 600 people
- Sponsor
- Ohio State University
Depression / Major Depressive Disorder, Anxiety Disorder (Panic Disorder or GAD)
Feasibility and Preliminary Outcomes of Compassion-Focused Group Therapy for Depression and Anxiety
This pilot study evaluated the feasibility and preliminary outcomes of compassion-focused group therapy (CFT) for adults with depression and/or anxiety who continued to experience symptoms despite previous treatment.
- Trial name
- NCT07876453
- Testing
- Compassion-Focused Group Therapy (CFT)
- Where
- Sweden
- Volunteers
- 21 people
- Sponsor
- Karolinska Institutet
Generalized Anxiety Disorder
Cognitive-Behavioral Therapy and Escitalopram for Generalized Anxiety Disorder(GAD)
The goals of this pilot study are as follows: 1) To disseminate and examine the effectiveness of a manualized, individual, cognitive-behavioral psychotherapy (CBT) for adults with Generalized Anxiety Disorder(GAD), 2) to test the…
- Trial name
- NCT00219349
- Testing
- Cognitive Behavioral Therapy, escitalopram
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- New York State Psychiatric Institute