Clinical trials: General Population
Vaccination Reaction
Longitudinal Evaluation of Antibody Kinetics of Vaccinated Patients With Non-mandatory Vaccine Following Administration of a Non-public Marketed Vaccine in the General Population, Real-life Study
The study would make it possible to document more explicitly the evolution of antibody titers at following a non-public vaccination over a large post-vaccination period in the French population .
- Trial name
- ELCAV (NCT06373510)
- Testing
- Blood collection
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- CerbaXpert
Post-traumatic Stress Disorder, Psychological Trauma
Prevalence of Post-traumatic Stress Disorder and Trauma Symptoms in a General Population Sample
The goal of this observational study is to learn about how many people have post-traumatic stress disorder and related symptoms in the general population of people without any mental illness in the Barcelona region of Catalonia…
- Trial name
- NCT05679245
- Testing
- Assessment for exposure to psychological trauma and related symptoms
- Where
- Spain
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Parc de Salut Mar
Constipation, Probiotic
Multi-strain Probiotic Effects on Self-Reported Constipation
Constipation is a prevalent gastrointestinal condition. Beyond simple lifestyle measures (e.g. increasing fibre intake, hydration, levels of exercise), medical therapies are available for management.
- Conditions
- Constipation, Probiotic, Probiotic Intervention
- Trial name
- NCT07275866
- Testing
- Multi-strain probiotics
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- Dr Anthony Hobson
Lifestyle, Dietary Habits
Analysis of Long Term Risk of Coronavirus Disease-19 Emergency
The aim of this study is to investigate dietary, lifestyle and psychosocial changes possibly occurred during Italy's lockdown, that is in the period of time between March 9 2020 and May 3 2020 (hereafter referred to as the Phase…
- Conditions
- Lifestyle, Dietary Habits, Psychosocial Problem
- Trial name
- ALTRISCOVID-19 (NCT04422262)
- Where
- Italy
- Volunteers
- 4,307 people
- Sponsor
- Neuromed IRCCS
Gingivitis
A Clinical Study to Evaluate the Efficacy of a Range of Dental/Denture Products for Improved Oral Health in Partial Denture Wearers
The purpose of this study is to investigate the effectiveness of usage of a range of oral products (toothpaste, mouth rinse, denture cleanser) on the oral health of partial denture wearers compared to existing oral hygiene…
- Trial name
- NCT04290624
- Testing
- Experimental Dentifrice: Stannous Fluoride, COREGA Denture Foaming Cleanser, Mouth rinse: Sodium Fluoride
- Where
- United Kingdom
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- HALEON
Type1diabetes
Screening for Islet Autoantibodies in the Israeli Paediatric General Population for Detection of Pre-symptomatic Type-1 Diabetes Mellitus
A national screening program for children aged 9 months-5 years that will be tested for the presence of islet autoantibodies.Up to 50,000 Children will be screened by their primary care physician all over Israel.
- Trial name
- ADIR (NCT04834518)
- Where
- 7 sites in Israel
- Volunteers
- 50,000 people
- Sponsor
- Rabin Medical Center
Mobility Limitation
Digitisation of the Timed Up and Go Test for the General Public
The question this feasibility study aims to answer is whether or not participants are able to accurately and reliably perform and self record the timed up and go test in a non-clinical environment using the Medopad application.
- Trial name
- NCT04229108
- Testing
- Medopad
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Andrew Gvozdanovic
Delirium
Ramelteon and Citicoline for Delirium
Primary aim of this study is to assess the feasibility of conducting clinical research for delirium (confusion due to medical problems) at Clements University Hospital in Dallas, Texas.
- Trial name
- NCT02840591
- Testing
- Ramelteon, Citicoline
- Where
- United States
- Sponsor
- University of Texas Southwestern Medical Center
Hip Fractures, COVID-19
Anesthesia Technique in COVID-19 Positive Hip Fracture Patients
Patients with COVID undergoing hip fracture repair have high mortality rates. If spinal anesthesia is associated with decreased rates of mortality, this study could provide hypothesis generating data for prospective studies.
- Conditions
- Hip Fractures, COVID-19, General Anesthesia, Spinal Anesthesia
- Trial name
- NCT05133648
- Testing
- Hip Fracture Surgery, COVID-19 infection
- Where
- Canada
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Elevated S-adenosylhomocysteine
Role of a Dietary Supplement in Lowering SAH in Healthy Adults With Elevated Plasma SAH and Normal Homocysteine Levels
S-adenosylhomocysteine (SAH) is the end-product of methylation reactions in the body and the precursor to homocysteine. Elevated SAH in the blood is a reflection of the dysregulation of what is known as the S-adenosylmethionine…
- Trial name
- SAH (NCT05994794)
- Testing
- Alpha-GPC, Creatine and Ashwagandha (Sensoril®)
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Standard Process Inc.
Celiac Disease
Coeliac Disease in the Nord-Trøndelag Health Study (HUNT)
In this study, all citizen of Nord-Trøndelag County, Norway, above 20 years of age are invited to participate in a population-based health study, the HUNT study.
- Trial name
- NCT04041622
- Testing
- Endoscopy and biopsy
- Where
- Norway
- Volunteers
- 56,000 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Prostatic Hyperplasia
Study to Evaluate the Therapeutic Action of Tamsulosin and Finasteride in Symptomatic Benign Prostatic Hyperplasia (BPH) Patients
Study to evaluate the therapeutic effect of tamsulosin and finasteride in symptomatic BPH patients, two medications indicated in BPH belonging to two different pharmacological classes, as evaluated from the point of view of…
- Trial name
- NCT02244229
- Testing
- Tamsulosin, Finasteride
- Volunteers
- 403 people
- Sponsor
- Boehringer Ingelheim
Cognition, Concentration
A Clinical Trial to Assess Cognitive Effects of Cognitive Nutritional Supplement in General Population
This is a double-blind, randomized, 12-week parallel study that aims to determine the effects of a cognitive nutritional supplement for 12 weeks on cognition parameters specific to attention/focus related domains, compared to a…
- Conditions
- Cognition, Concentration, Attention, Focus
- Trial name
- NCT06837246
- Testing
- Cognitive Nutritional Supplement
- Where
- United States
- Volunteers
- 422 people, healthy volunteers welcome
- Sponsor
- Pharmavite LLC
Aged (80 or More), Healthy
Development of General Practitioners Screening Tool of Frail Older Old Community
The comprehensive geriatric assessment (CGA) is a multidimensional, interdisciplinary diagnostic process to determine the medical, psychological, and functional capabilities of an elderly person, in order to develop a coordinated…
- Trial name
- ReperAge (NCT02087982)
- Where
- France
- Volunteers
- 840 people, healthy volunteers welcome
- Sponsor
- Gerontopôle des Pays de la Loire
Hypertension
Attitudes and Understanding of Sodium Claims on Food Labels
Sodium-related claims on food labels should help people find lower sodium food choices; however consumer attitudes and understanding of such claims are unknown.
- Trial name
- NCT01764724
- Testing
- Mock package questionnaire
- Where
- Canada
- Volunteers
- 987 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Respiratory Viral Infection
Evaluation of the Detection Performance of the N Antigenemia of SARS-CoV-2 in the General Population for the Diagnosis and Screening of COVID-19
SARS-CoV-2 is responsible for COVID-19. Today, RT-PCR performed on a nasopharyngeal sample remains the gold standard for diagnosing SARS-CoV-2 infection.
- Trial name
- CoviBlood (NCT05092607)
- Testing
- Venous and Capillary blood sampling
- Where
- France
- Volunteers
- 1,467 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Generalized Epidermolysis Bullosa Simplex
An International, Multicenter, Randomized, Double-Blind, Parallel Group, Vehicle-Controlled, Phase 2/3 Study With Open-Label Extension Evaluating the Efficacy and Safety of Diacerein 1% Ointment for the Treatment of Generalized Epidermolysis Bullosa Simplex (EBS)
The proposed Phase 2/3 trial with double-blind and open-label extension phases is an international, multicenter study designed to assess the efficacy and safety of diacerein 1% ointment in patients with generalized EBS.
- Trial name
- EBShield (NCT06073132)
- Testing
- AC-203, Vehicle
- Where
- 30 sites in United States, Australia and 16 more
- Volunteers
- 80 people
- Sponsor
- TWi Biotechnology, Inc.
Insulin Resistance, Hyperinsulinism
Link Between the Peripheral Mononuclear Cells' Capacity to Induce Insulin Resistance and Hyperinsulinemia
This is a two-center proof-of-concept study, ancillary to the MetACTIV study, whose objective is to define immune activation profiles from the data of individuals followed by the Caisse Primaire d'Assurance Maladie du Gard…
- Conditions
- Insulin Resistance, Hyperinsulinism, Immune System
- Trial name
- IRACTIV (NCT05329337)
- Testing
- Blood test
- Where
- 2 sites in France
- Volunteers
- 30 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Critical Care
Long-term Mortality After Intensive Care Considering Comorbidity and Admission Diagnoses
This is a register-based study The aim of this study is to investigate how common comorbidity is in different age groups and which comorbidity that has the greatest impact on mortality considering different admission diagnosis…
- Trial name
- NCT06234709
- Where
- Sweden
- Volunteers
- 200,000 people
- Sponsor
- Anna Aronsson
Stress, Generalized Anxiety
Enhancing Health in Rural Populations: Music as Therapy
The goal of this clinical trial is to learn whether a music-based intervention can improve mental and physical health and strengthen coping skills among adults living in residential care settings in northern Arizona.
- Conditions
- Stress, Generalized Anxiety, Chronic Pain, Depression Disorder
- Trial name
- NCT07538427
- Testing
- Music Based Intervention
- Where
- 2 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Northern Arizona University