Clinical trials: General Surgery
Rhegmatogenous Retinal Detachment
Clinical Trial of Cryotherapy Versus Postoperative Laser Photocoagulation
The purpose of this randomized clinical trial was to compare reattachment rates among patients with rhegmatogenous retinal detachment who underwent scleral buckle surgery with retinopexy by cryotherapy versus postoperative (one…
- Trial name
- NCT01068379
- Testing
- criopexy, laser
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- University of Campinas, Brazil
Endometriosis, Pelvic Pain
Medical Treatment of Endometriosis-Associated Pelvic Pain
The Specific Aim of this project is to compare the efficacy and cost-effectiveness of continuous oral contraceptives versus leuprolide/norethindrone in the treatment of endometriosis-associated chronic pelvic pain.
- Trial name
- NCT00229996
- Testing
- Oral Contraceptive, Depot-Leuprolide/Norethindrone
- Where
- United States
- Volunteers
- 194 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Anxiety, Sleep
Preoperative Hip Knee Anxiety Sleep Study
This study is about assessing the impact of reading previous patients' stories related to their hip or knee replacement surgery on patients' preoperative anxiety and sleep.
- Conditions
- Anxiety, Sleep, Surgery
- Trial name
- NCT04180527
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Henry Ford Health System
Gingival Recession
Guided Creeping Technique (GCT) in Treating Gingival Recession
A novel minimally invasive guided creeping technique (GCT) is suggested to treat gingival recessions.
- Trial name
- NCT05101642
- Testing
- Guided Creeping Technique (GCT)
- Where
- Egypt
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- October 6 University
Breast Self-Examination, Breast Cancer
Experimental Study With Pretest/Posttest Groups Which the Intervention Group Have the System Which Sends Reminder Notifications Directing Them to the Website Containing BSE Training Along With the Illustrations Created for the Practice Prepared by the Researcher on the Determined Ideal Day
H0: Among the intervention and control groups of reminder notifications relating to self-examination H01: Average breast cancer fear score and H02: There is no difference in the average score of breast cancer health beliefs.
- Conditions
- Breast Self-Examination, Breast Cancer, Nursing Caries, Cancer
- Trial name
- BreastSelfExam (NCT05995483)
- Testing
- Early Diagnosis on BSE
- Where
- Cyprus
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Eastern Mediterranean University
Reconstructive Surgery
PRF and Connective Tissue Graft in Interdental Papilla Reconstruction
Interdental papilla deficiency leads to food impaction, problems with phonetics and an unaesthetic appearance. Reconstruction of the deficient papilla is therefore, important.
- Trial name
- NCT03899051
- Testing
- interdental papilla reconstructive surgery with PRF, interdental papilla reconstructive surgery with subepithelial connective tissue graft
- Where
- India
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Obesity, Diabetes Mellitus, Type 2
The Effect of Bariatric Surgery on Insulin Sensitivity and Energy Metabolism
The purpose of this study is: 1. To explore to what extent insulin sensitivity, energy metabolism and ectopic lipid storage can be improved by bariatric surgery 2.
- Trial name
- BARIA-DDZ (NCT01477957)
- Testing
- surgery
- Where
- Germany
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- German Diabetes Center
Fibula / Surgery, Surgical Flaps
Novel Application of a Low-cost Alternative to Patient Specific Implants (PSI) in Mandibular Free Fibula Flap Reconstruction by Reverse Engineering of Stock Plates: A Pilot Validation Study
Stock reconstruction plates have been used for decades and represent a tried-and-true alternative to custom plating. Stock plates are readily available, are cost effective, and can be accurately bent before surgery, particularly…
- Conditions
- Fibula / Surgery, Surgical Flaps, Computer-Aided Design, Mandibular Reconstruction* / Methods
- Trial name
- NCT05672056
- Testing
- Computer guided placement of a stock plate pre-bent on a 3D printed model
- Where
- Egypt
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Cairo University
Surgery
Buccal Graft + Collagen Matrix Versus Free Gingival Graft for Keratinized Mucosa Augmentation at Implant Sites
The study aims at comparing two different approaches for soft tissue augmentation at implants lacking keratinized and adherent mucosa width: the free gingival graft (FGG) vs the Buccal Strip Graft in combination with a xenogeneic…
- Trial name
- FGGvsBSG+CM (NCT05844475)
- Testing
- Conventional Free Gingival Graft Approach (FGG), Buccal Strip Graft with a collagen matrix (bSG + CM)
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Harvard Medical School (HMS and HSDM)
Hypoglycemia
Mechanisms of Post-Bariatric Hypoglycemia
Post-bariatric hypoglycemia (PBH) is an increasingly recognized syndrome that is incompletely understood. The purpose of this study is to increase our level of understanding by investigating mechanisms contributing to this…
- Trial name
- NCT04428866
- Testing
- Continuous Glucose Monitoring, activity monitor, Mixed meal tolerance test
- Where
- United States
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Joslin Diabetes Center
Lung Cancer, Surgery
CMR Right Ventricular Contractile Reserve Following Lung Resection
Feasibility study investigating CMR dobutamine stress testing before and after lung resection
- Conditions
- Lung Cancer, Surgery, Anesthesia
- Trial name
- NCT06465277
- Testing
- Dobutamine stress CMR, Cardiac biomarker sample
- Where
- United Kingdom
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Belfast Health and Social Care Trust
Atrial Fibrillation
Fish Oil for Reduction of Atrial Fibrillation After Cardiac Surgery
The primary objective of this study is to determine if omega-3 polyunsaturated fatty acids reduce atrial fibrillation and other outcomes after cardiac surgery.
- Trial name
- FISH (NCT00446966)
- Testing
- Omega Three Polyunsaturated fatty acids
- Where
- United States
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- Chirag Sandesara
Breast Cancer, Breast Surgery
Hemodynamic Effects of Intradermal Methylene Blue During Breast Surgery Under General Anesthesia
This prospective observational study aims to evaluate the effects of intradermal methylene blue injection on intraoperative hemodynamic stability in patients undergoing breast surgery under general anesthesia.
- Conditions
- Breast Cancer, Breast Surgery, Sentinel Lymph Node Biopsy, Methylene Blue
- Trial name
- NCT07040540
- Testing
- Methylene Blue, Standard Surgical Care Without Dye
- Where
- Turkey (Türkiye)
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital
Lung Cancer
A Feasibility Study of Unsupervised, Pre-operative Exercise Program for Patients Scheduled for Lung Cancer Surgery
The paradigm of pre-operative exercise as a neoadjuvant therapy to reduce morbidity is increasingly promoted within general surgery and surgical oncology.
- Trial name
- NCT03162718
- Testing
- Exercise
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Dartmouth-Hitchcock Medical Center
Appendicitis, Surgery
Raja Isteri Pengiran Anak Saleha Appendicitis Treatment Without Operation
The RIPASA score is a Clinical Prediction Rule (CPR) for the diagnosis of acute appendicitis. Since its inception in 2009, the RIPASA score has been validated in various population in healthcare institutions around the world and…
- Trial name
- RIPASA-TWO (NCT03169114)
- Testing
- Amikacin Injection, Appendicectomy
- Where
- Brunei
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Raja Isteri Pengiran Anak Saleha Hospital
Breast/Surgery
Nipple-sparing Mastectomy in Combined With Buried Flap Monitoring
1. Learning curve of ms-Tram and DIEP breast reconstructions surgery are important to guide the training of new surgeon. 2. Buried flap post operative monitoring without implantable doppler was seldom studied, a validated…
- Trial name
- NCT05560633
- Testing
- No intervention
- Volunteers
- 147 people, healthy volunteers welcome
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Le Fort; I, Blood Loss
Impact of Different Instrument Modifications on Lateral Nasal Wall Osteotomy and Pterygomaxillary Separation in Le Fort I Surgery
The aim of this study is to investigate the effect of different instrument modifications on the customized osteotomy of the lateral nasal wall in Le Fort I surgery, focusing on the level of lateral nasal wall fractures and the…
- Trial name
- NCT06629935
- Testing
- orthognathic surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
COVID-19, Bariatric Surgery Candidate
Bariatric Surgery and COVID-19
The National Bariatric Surgical Registry (NBSR) is a prospectively collected database for all patients undergoing elective bariatric surgery in the UK.
- Trial name
- NCT05532891
- Testing
- COVID-19 pandemic
- Where
- United Kingdom
- Volunteers
- 11,545 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Degenerative Lumbar Spondylolisthesis
Degenerative Spondylolisthesis; Micro-decompression vs Decompression + Instrumented Fusion; Long Term Follow up
In many countries a majority of patients with degenerative spondylolisthesis are operated on with decompression plus instrumented fusion, but the scientific evidence for adding fusion is controversial.
- Trial name
- DS-registry (NCT03469791)
- Testing
- Surgical treatment of Degenerative Spondylolisthesis
- Where
- Norway
- Volunteers
- 426 people, healthy volunteers welcome
- Sponsor
- Haukeland University Hospital
Pain Due to Certain Specified Procedures
Single Injection Infromedial Peribulbar Injection in Lacrimal Duct
infromedial injection of 3 ml local anesthetic drugs and assessing the pain during lacrimal duct intubation and probability of false tracking
- Trial name
- NCT04859049
- Testing
- infromedial single injection, medial canthus injection
- Where
- 2 sites in Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Research Institute of Ophthalmology, Egypt
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.