Clinical trials: General Surgery
Postoperative Pain, Narcotic Use
Novel Multimodal Pain Control Protocol for Minimally Invasive Gynecologic Surgery
The study is a randomized controlled trial investigating a multimodal postoperative pain management protocol which will include use of ice therapy and scheduled opioid-sparing medications for pain control after minimally invasive…
- Conditions
- Postoperative Pain, Narcotic Use, Cryotherapy Effect
- Trial name
- NCT04710277
- Testing
- Opioid-sparing multimodal pain management, Usual care
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Pelvic Organ Prolapse, Urinary Incontinence
Chlorhexidine vs. Iodine for Vaginal Preparation in Urogynecologic Procedures
This is a randomized controlled trial to determine if there is a difference between chlorhexidine gluconate and povidone iodine vaginal preparations for urogynecological surgery post operative infections.
- Conditions
- Pelvic Organ Prolapse, Urinary Incontinence, Pelvic Floor Disorders, Gynecologic Disease
- Trial name
- CLNUP (NCT04048356)
- Testing
- Vaginal scrub, to be applied vaginally and perineally immediately prior to surgery.
- Where
- United States
- Volunteers
- 137 people, healthy volunteers welcome
- Sponsor
- University of New Mexico
Gastric Bypass, Body Weight
Pharmacokinetic Evaluation of Moxifloxacin Administered Intravenously and Orally in Healthy Volunteers Who Have Had a Gastric Bypass
Roux-and-Y gastric bypass is one of the most common forms of bariatric surgery; due to a reduction in size of the stomach and intestine, the available surface area for the absorption of oral drugs is strongly decreased.
- Trial name
- DRUG10_MOXI (NCT01130922)
- Testing
- moxifloxacin per IV, moxifloxacin per os
- Where
- Belgium
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University Ghent
Sleep Apnea, Obstructive
Prescision Medicine in Obstructive Sleep Apnea, Cardiovascular and Cerebrovascular Disease: AI Electrocardiogram Patch Does it All
Obstructive Sleep apnea(OSA) is a disease with multiple causes, and treatments are very diverse. Patients and doctors have a lot of choices.
- Trial name
- NCT05566860
- Testing
- Positional Therapy, Intraoral Negative Pressure Therapy, Oral Appliances
- Where
- Taiwan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Shin Kong Wu Ho-Su Memorial Hospital
Thoracic Surgery
The Effect of Permissive Hypercapnia on Oxygenation and Post-operative Pulmonary Complication During One-lung Ventilation
Permissive hypercapnia increased the survival rate in patients with acute respiratory distress syndrome (ARDS) who required mechanical ventilation in critical care medicine.
- Trial name
- NCT04175379
- Testing
- group 40, group 50, group 60
- Where
- South Korea
- Volunteers
- 279 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Laparoscopic Surgery, Music
EffectS of prEferred Music on Laparoscopic performancE
The main objective is to investigate whether listening to recorded music has a positive effect on the execution of laparoscopic skills.
- Conditions
- Laparoscopic Surgery, Music, Surgical Education
- Trial name
- EnSEMbLE (NCT04111679)
- Testing
- Music
- Where
- Netherlands
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Erasmus Medical Center
Laparoscopy Training, Robotic Surgery Training
Comparison of da Vinci Simulator vs LapSim Simulator
Virtual reality surgical simulators (VRSS) are gaining popularity for general surgery training, both for conventional laparoscopic and robotically-assisted surgery.
- Trial name
- NCT03079908
- Testing
- da Vinci Skills Simulator®, LapSim®, Dry lab box laparoscopic training
- Where
- Switzerland
- Volunteers
- healthy volunteers welcome
- Sponsor
- Klinik für Allgemein- und Viszeralchirurgie, Department Chirurgie, Luzerner Kantonsspital
Obesity, Morbid
Safe and Easy Access Technique for the First Trocar in Laparoscopic Obesity Surgery
Laparoscopic surgery has become very popular and standard in many indications after advancements of technique. Various methods have been used in first entry to the abdomen.
- Trial name
- NCT03015935
- Testing
- visual-assisted entry, Veress entry
- Where
- Turkey (Türkiye)
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Umraniye Education and Research Hospital
Scoliosis
Tranexamic Acid in Pediatric Scoliosis Surgery
This study aims to investigate whether intraoperative administration of tranexamic acid based on ROTEM® (Rotational Thromboelastometry), in pediatric patients undergoing scoliosis surgery, results in a difference in…
- Trial name
- NCT06091891
- Testing
- Tranexamic acid, Tranexamic acid infusion under ROTEM-guidance
- Where
- South Korea
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Brachial Plexus Block, Pulmonary Ventilation
Ventilation and Pulmonary Aeration, Electrical Impedance Tomography, Interscalene Brachial Plexus Block
Patients with indication of shoulder surgery will be submitted to ultrasound-guided interscalene brachial plexus block with 4ml or 15ml of bupivacaine- epinephrine 0,5%- 1:200,000 at level of C5-6 roots and will be evaluated…
- Trial name
- NCT03577860
- Testing
- Bupivacaine 4 mL, Bupivacaine 15 mL
- Where
- 2 sites in Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Arterial Thromboembolic Events, Atrial Fibrillation
Effectiveness of Bridging Anticoagulation for Surgery (The BRIDGE Study)
Blood thinners, such as warfarin, prevent blood clots from forming, thereby reducing the risk of a stroke or heart attack. When people undergo surgery or certain procedures, they must stop using warfarin to prevent too much…
- Trial name
- NCT00786474
- Testing
- Dalteparin
- Where
- United States
- Volunteers
- 1,884 people, healthy volunteers welcome
- Sponsor
- Duke University
Optic Nerve Sheath Diameter, Pneumoperitoneum
Comparison of Changes of ONSD Between Groups of Laparoscopic Surgery With and Without Epidural Saline Injection
This study targets patients undergoing laparoscopic gastric cancer surgery. The investigators would like to compare two factors that influence intracranial pressure through optic nerve sheath diameter measurement.
- Conditions
- Optic Nerve Sheath Diameter, Pneumoperitoneum, Epidural
- Trial name
- NCT04758013
- Testing
- Epidural injection through thoracic epidural catheter, Without epidural injection
- Where
- South Korea
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Keimyung University Dongsan Medical Center
Pain, Surgery
The Possible Correlations Between the Genes Related to Pain Sensation and the Pain Sensitivity in the General Population
Objective: This study was conducted to explore the possible correlation between some gene related to pain sensation and individual basal pain perception and postoperative pain intensity in the general population.
- Trial name
- NCT01950078
- Where
- China
- Volunteers
- 1,533 people, healthy volunteers welcome
- Sponsor
- Xianwei Zhang
Obesity
Feasibility of Use of BariCare App in Pre-bariatric Surgery.
This current study aims to evaluate the efficacy of engagement modules in preparing patients for bariatric surgery. With the help of the Center for Innovation (CFI), a smartphone app (Android and Apple compatible) has been…
- Trial name
- NCT01708135
- Testing
- Use of smartphone app
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Inflammatory Response
The Effects of Surgery Performed At Different Times of the Day on Inflammation and Recovery
To evaluate the inflammatory response of participants who will undergo unilateral inguinal hernia surgery at two different times of the day (08.00-12.00 during the day and 18.00-22.00 at night).
- Trial name
- NCT06345313
- Testing
- Day Group, Night Group
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Surgical Stress Response, Stress Physiological
Feasibility of Breathwork Intervention With Older Adults After Knee Surgery
Postoperative complications after surgical procedures, including following total knee arthroplasty (TKA), have a negative impact on the health and well-being of surgical patients.
- Conditions
- Surgical Stress Response, Stress Physiological, Stress Physiology, Stress Psychological
- Trial name
- NCT07464860
- Testing
- A 5-minute Asynchronous Breathwork Intervention, A 5-minute Asynchronous Card Game Video
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Colorectal Disease
Evaluation of a TAP Block Given During Laparoscopic Colorectal Surgery to Help Control Pain
Patients experience pain after surgery mostly from their abdominal wounds, even when those wounds are small. Decreasing that pain has many benefits.
- Trial name
- TAP Block (NCT01731782)
- Testing
- bupivacaine
- Where
- United States
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Coronary Artery Diseases, Valvular Heart Diseases
Clinical and Hospital Stay Effects of Reiki and Manual Therapy After Open Heart Surgery
Reiki is an energy-based healing therapy using light touch. Manual therapy is a technique using light effleurage. These complimentary healing services are utilized to promote relaxation, sleep, improve emotions, and decrease…
- Trial name
- NCT05853250
- Testing
- Reiki/manual therapy
- Where
- United States
- Volunteers
- 272 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Colorectal Cancer
Efficacy of Single Incision (Embryonic NOTES) Laparoscopic Colorectal Surgery
Laparoscopic colon surgery has been performed widely. As a minimal invasive approach, single incision (Embryonic NOTES) colon surgery has been attempted.
- Trial name
- NCT01269060
- Testing
- Single Incision Laparoscopic Surgery
- Where
- South Korea
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- National Cancer Center, Korea
Pain, Postoperative
Erector Spina Plane Block Volume Comparison
After obtaining ethical committee approval from Kahramanmaras University Anesthesiology and Reanimation Department and Urology Clinic, 60 patients between 18-65 years old who meet ASA I-II classification criteria with body mass…
- Trial name
- NCT06332313
- Testing
- erector spina plane block
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kahramanmaras Sutcu Imam University
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