Clinical trials: General Surgery
Agitation States as Acute Reaction to Gross Stress
Efficacy of External Nasal Nerve Block in Prevention of Postoperative Agitation Following Nasal Surgeries
Emergence agitation following general anaesthesia may lead to serious complications like self-extubation or removal of catheters, which can lead to hypoxia, aspiration pneumonia, bleeding or reoperation.
- Trial name
- NCT03069027
- Testing
- External nasal nerve block, saline adrenaline, Xylocaine, adrenaline
- Where
- Saudi Arabia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Al Jedaani Hospital
Cataract, Nursing Caries
Effects of Music and Stress Ball Application on Patients During Cataract Surgery
Cataract is one of the leading causes of preventable blindness in the world and in Türkiye. Cataract surgery is one of the most frequently performed and most reliable surgeries for eye diseases.
- Trial name
- NCT06555770
- Testing
- Music intervention, Stress ball
- Where
- Turkey (Türkiye)
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Knee Prosthesis, Cryotherapy
Pressurized Cold Application for Patients Total Knee Prosthesis Surgery
This study was conducted to examine the effects of pressurized cold applicatıon for patients total knee prosthesis surgery.
- Conditions
- Knee Prosthesis, Cryotherapy, Pain, Patient Satisfaction
- Trial name
- NCT05233423
- Testing
- compressed cold therapy bandage
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Pamukkale University
Pain
IV Acetaminophen for Postoperative Pain Analgesia After Laparoscopic Hysterectomy
The objective of this study is to quantify the change in post-operative pain scores and narcotic requirements in women receiving pre and post-operative IV acetaminophen compared to placebo in women undergoing laparoscopic…
- Trial name
- NCT02400580
- Testing
- IV acetaminophen
- Where
- United States
- Volunteers
- 183 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Throat, Sore
Pilot Study of Throat Packs Soaked in Gengigel Spray in Patients Undergoing Elective Surgery
Throat packs are commonly used in many surgical procedures involving the oral cavity and pharynx, primarily to prevent blood, saliva, and other debris from entering the lower respiratory tract, thereby maintaining a clear airway…
- Trial name
- NCT06947161
- Testing
- Gengigel
- Where
- Malaysia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Opioid Use
Does Altering Narcotic Prescription Methods Affect Opioid Distribution Following Select Upper Extremity Surgeries?
It has been well established that prescription opioid misuse and prescription opioid abuse is on the rise. In the late 1990's and early 2000's, there was a large push to make "pain" the fifth vital sign.
- Trial name
- NCT03570320
- Testing
- Modification of opioid prescription method
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- John Yanik
Virtual Reality, Symptom Management
Applicability and Efficiency of Virtual Reality Intervention in Knee Surgery Patients
The stress experienced by patients in hospital environments can lead to a range of issues, from clinical decision-making to discharge.
- Conditions
- Virtual Reality, Symptom Management, Surgery, Quality of Life
- Trial name
- NCT06311994
- Testing
- Virtual reality
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Gümüşhane Universıty
Abnormal Labial Frenum Frenectomy, Frenectomy
Pain After Diode Laser Frenectomy in Children
This prospective single-group clinical study aims to evaluate postoperative pain following diode laser-assisted frenectomy in pediatric patients and to assess the agreement between different pediatric pain assessment scales.
- Trial name
- PED-FREN (NCT07706023)
- Testing
- Diode Laser-Assisted Frenectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Afyonkarahisar Health Sciences University
Etomidate Combined With Propofol, Hypertension
Safety of Etomidate-propofol Mixture vs. Propofol for Total Intravenous Anesthesia in Elderly Patients Undergoing Abdominal Surgery
The purpose of this study is to access the safety of etomidate - propofol mixture vs propofol for total intravenous anesthesia in elderly patients undergoing abdominal surgery.
- Trial name
- NCT07019246
- Testing
- EP mixture, Propofol
- Where
- China
- Volunteers
- 166 people, healthy volunteers welcome
- Sponsor
- Tongji Hospital
Ophthalmology, Photorefractive Keratectomy ("PRK")
Ocular Bandage Gel (OBG) Pivotal Trial in Patients Undergoing Photorefractive Keratectomy ("PRK")
Prospective, randomized, masked (reading center), controlled pivotal study of Ocular Bandage Gel (OBG) vs. a bandage contact lens (BCL) in subjects who have undergone bilateral photorefractive keratectomy (PRK).
- Conditions
- Ophthalmology, Photorefractive Keratectomy ("PRK"), Laser Assisted Surgery, Refractive Surgery
- Trial name
- NCT03938883
- Testing
- Ocular Bandage Gel (OBG), Bandage Contact Lens (BCL)
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Eyegate Pharmaceuticals, Inc.
Anesthesia
VR Sedation in Third Molar Surgery
Anaesthesia or sedation for dental surgery is Challenging. Over-sedation, leading to upper airway obstruction, desaturation and apnoea, is very common.
- Trial name
- NCT04540666
- Testing
- Propofol
- Where
- Hong Kong
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Radius Fractures
Comparison 1 Plane-2 Injection and 2 Plane-2 Injection Ultrasound-guided Supraclavicular Brachial Plexus Block
The supraclavicular block can provide effective surgical anesthesia of the forearm and hand. There have been many different approaches to ultrasound-guided supraclavicular brachial plexus block (US-SCBPB) according to the needle…
- Trial name
- US-SCBPB (NCT02533557)
- Testing
- stimuplex insulated needle, lidocaine mixed with epinephrine
- Where
- South Korea
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Gachon University Gil Medical Center
Lumbar Decompression
MRI Outcomes of VersaWrap Nerve Protector Following Surgery
The purpose of this study is to evaluate enhancement patterns in magnetic resonance imaging (MRI) evidence following the use of VersaWrap in bilateral lumbar decompression surgeries.
- Trial name
- NCT06942819
- Testing
- VersaWrap Nerve Protector
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Research Source
Caesarean Wound, Hypertrophic Surgical Scar
: Protescal: Prevention of Hypertrophic Scar and Keloid Formation Post Caesarean Section
This study aimed to evaluate the effectiveness of Protescal in preventing post caesarean section hypertrophic scar and keloid formation.
- Conditions
- Caesarean Wound, Hypertrophic Surgical Scar, Keloid Scar Following Surgery
- Trial name
- NCT04951869
- Testing
- Protescal gel
- Where
- Malaysia
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Universiti Kebangsaan Malaysia Medical Centre
Bariatric Surgery Candidate
Extended Pouch Gastric Bypass vs One-anastomosis Gastric Bypass in Patients With BMI≥45
The classic RYGB is in most patients with a BMI ≥45 technically not feasible. Two alternatives are the Extended Pouch Gastric Bypass and the One Anastomosis gastric bypass.
- Trial name
- EXPANT (NCT06204939)
- Testing
- Randomizing for EPGB procedure, Randomizing for OAGB procedure
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- L. van Hogezand
Periodontal Diseases
Photobiomodulation and Platelets Rich in Growth Factors (PRGFs)-Assisted Flap Surgery in Treating Stage III Periodontal Defects
Stage 3 periodontitis is a condition marked by swift and severe destruction of periodontal tissues. To effectively regenerate osseous defects resulting from periodontal disease, it is crucial to leverage the intrinsic…
- Trial name
- NCT06641739
- Testing
- laser assisted SPPF, Platelet Rich Plasma
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Assiut University
Postoperative Pain, Fear
Designing Animated Movie for Preoperative Period
Background: Using visual materials is effective in education to decrease children's pre-operative fear and post-operative pain. Children, especially those aged between 6 and 12 years, are interested in technology.
- Conditions
- Postoperative Pain, Fear, Surgery, Pain
- Trial name
- NCT04176822
- Testing
- Educational animated movie group, Documentary movie group
- Where
- Turkey (Türkiye)
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Ege University
Myopia
A Prospective, Contralateral, Eye to Eye Comparison of SMILE Surgery to LASIK Surgery
Subjects will undergo SMILE surgery in one eye and LASIK surgery in their other eye to correct myopia.
- Trial name
- NCT03067077
- Testing
- SMILE, LASIK
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Stanford University
Cataract
Comparison of a New EDOF-IOL With a Standard-EDOF-IOL
Comparison of the new extended depth of focus (EDOF) intraocular lens (IOL) ARTIS ACTIVE, which is designed as a twinset of IOLs, with the standard EDOF IOL AT Lara .
- Trial name
- NCT03921762
- Testing
- Cataract surgery with Artis Active IOLs, Cataract surgery with AT Lara IOLs
- Where
- Austria
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Prim. Prof. Dr. Oliver Findl, MBA
Impacted Third Molar Tooth
EFFICACY OF ICE PACK THERAPY AFTER IMPACTED THIRD MOLAR SURGERY
this study evaluates the effect of cold application after impacted third molar extractions. Patients have bilateral impacted third molar tooth included in this study.
- Trial name
- NCT03261869
- Testing
- Cold application
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Baskent University
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