Clinical trials: Generalized Anxiety Disorder (GAD)
Generalized Anxiety Disorder
Evaluating The Effects Of Cimetidine On The Elimination Of PD 0332334 From The Body
The purpose of this study is to estimate the effects of multiple doses of cimetidine on the pharmacokinetics of a single dose of PD 0332334 and to evaluate the safety and tolerability of PD 0332334 when co-administered with…
- Trial name
- NCT00800280
- Testing
- PD 0332334, cimetidine
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Pfizer
Peripheral Vascular Diseases
Examining the Impact of Exercise Training on Vascular Dysfunction in Individuals With Mental Health Disorders - Study 1
The purpose of this research study is to examine the role oxidants, substances produced in the blood that can damage blood vessel function, may play in blood vessel function in healthy individuals as well as individuals with…
- Trial name
- NCT04916327
- Testing
- Antioxidant
- Where
- United States
- Volunteers
- 720 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Generalized Anxiety Disorder
Efficacy and Safety Study of a IMSS Developed Phytopharmaceutical for the Treatment of Anxiety.
The investigator's group at the Mexican Institute of Social Security has worked for more than 20 years in the scientific research of the plant species Galphimia glauca Cav., which is used in Mexican Traditional Medicine for the…
- Trial name
- Alpra (NCT03702803)
- Testing
- Galphimia glauca standardized extract, alprazolam 1mg
- Where
- Mexico
- Volunteers
- 122 people
- Sponsor
- Coordinación de Investigación en Salud, Mexico
Mental Health Issue (E.G., Depression, Psychosis, Personality Disorder, Substance Abuse), Schizophrenia
INCLUDE: Using Lived Experience to Improve Mental Health Diagnosis v1
The focus of this study is not about what it is like to have a mental disorder, but instead the diagnostic experience. Some people find diagnoses helpful, but some find them upsetting and harmful.
- Conditions
- Mental Health Issue (E.G., Depression, Psychosis, Personality Disorder, Substance Abuse), Schizophrenia, Generalised Anxiety Disorder, Bipolar Disorder
- Trial name
- INCLUDE (NCT03131505)
- Where
- United Kingdom
- Volunteers
- 59 people
- Sponsor
- Norfolk and Suffolk NHS Foundation Trust
Autoimmune Encephalitis
Impact of Confirmed Autoimmune Encephalitis on Brain Glucose Metabolism
Prospective cohort study evaluating FDG PET in 56 patients with confirmed autoimmune encephalitis - based on 2016 Graus criteria, and 2021 paraneoplastic neurological syndromes criteria - at the acute phase, before…
- Trial name
- ENCEPHATAIP (NCT06079294)
- Testing
- FDG PET
- Where
- France
- Volunteers
- 56 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Anxiety Disorders, Generalized Anxiety Disorder
Drug Therapy for Generalized Anxiety Disorder Among the Elderly
This study will determine the efficacy of escitalopram (Lexapro®), an anti-anxiety drug, for generalized anxiety disorder (GAD) and the ways genetics affect response to treatment for GAD in elderly individuals.
- Trial name
- NCT00105586
- Testing
- Escitalopram
- Where
- United States
- Volunteers
- 177 people
- Sponsor
- University of Pittsburgh
Anxiety Disorder
A Long-Term Study Continuing on From Study 04-001-01 of an Experimental Medication in Adults With Anxiety Disorder
The purpose of the study is to assess the safety and effectiveness of the experimental drug, a benzodiazepine drug, in long-term use and the effects on quality of life, social and occupational functioning, sleep, and daytime…
- Trial name
- NCT00106860
- Testing
- a benzodiazepine drug
- Where
- 13 sites in United States
- Volunteers
- 158 people, healthy volunteers welcome
- Sponsor
- Jazz Pharmaceuticals
Posttraumatic Stress Disorder, Major Depressive Disorder
An Augmented Training Program for Preventing Post-Traumatic Stress Injuries Among Diverse Public Safety Personnel
Public safety personnel (PSP; e.g., border services personnel, correctional workers, firefighters, paramedics, police, public safety communicators) are frequently exposed to potentially psychologically traumatic events.
- Conditions
- Posttraumatic Stress Disorder, Major Depressive Disorder, Panic Disorder, Generalized Anxiety Disorder
- Trial name
- NCT05530642
- Testing
- Emotional Resilience Skills Training (ERST)
- Where
- Canada
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- University of Regina
Depression, Anxiety Disorders
Effectiveness & Cost-effectiveness of Internet-delivered Interventions for Depression and Anxiety Disorders in IAPT
Depression and anxiety are common mental health problems. There are effective treatments for depression and anxiety and one of these is talking therapies using cognitive behaviour therapy (CBT).
- Conditions
- Depression, Anxiety Disorders, Depressive Disorder, Generalized Anxiety Disorder
- Trial name
- D-IAPT (NCT03188575)
- Testing
- SilverCloud Internet-delivered Cognitive Behavioural Therapy, Waiting List
- Where
- United Kingdom
- Volunteers
- 384 people
- Sponsor
- Silver Cloud Health
Posttraumatic Stress Disorder (PTSD), Generalized Anxiety Disorder (GAD)
Metacognitive Therapy vs Unified Protocol for Patients With Comorbid Anxiety Disorders
The primary goal of this randomized controlled trial is to compare the effectiveness of two transdiagnostic psychological treatments, Metacognitive Therapy (MCT) and the Unified Protocol for Transdiagnostic Treatment of Emotional…
- Conditions
- Posttraumatic Stress Disorder (PTSD), Generalized Anxiety Disorder (GAD), Social Anxiety Disorder (SAD), Panic Disorder (With or Without Agoraphobia)
- Trial name
- NCT06971692
- Testing
- Metacognitive therapy (MCT), Unified protocol (UP)
- Where
- Sweden
- Volunteers
- 114 people
- Sponsor
- Karolinska Institutet
Generalized Anxiety Disorder
A Single-Component CBT for GAD
Generalized Anxiety Disorder (GAD) is a chronic condition that is characterized by excessive and uncontrollable worry and anxiety. In Canada, 3 to 4% of the population suffer from GAD at any point in time.
- Trial name
- NCT02552108
- Testing
- Behavioural experiments for intolerance of uncertainty (BE-IU)
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universite du Quebec en Outaouais
Analogue Generalized Anxiety Disorder
The Resistance Exercise Training for Worry Trial: Replication and Expansion
This protocol details the full methods of a ten-week moderate-to-high intensity, guidelines-based resistance exercise training intervention compared to a low intensity sham attention control among young adult women with analogue…
- Trial name
- RETRAIN REP-EX (NCT06804629)
- Testing
- Moderate-to-High Intensity Resistance Exercise Training
- Where
- Ireland
- Volunteers
- 68 people
- Sponsor
- University of Limerick
Anxiety Disorders, Panic Disorder
Initial Severity and Antidepressant Efficacy for Anxiety Disorders: an Individual Patient Data Meta-analysis
Anxiety disorders are common disorders, which pose a major burden to society and the individual. An anxiety disorder may be treated with medication, in particular with antidepressants such as the selective serotonin reuptake…
- Conditions
- Anxiety Disorders, Panic Disorder, Obsessive-compulsive Disorder, Post-traumatic Stress Disorder
- Trial name
- NCT02476136
- Testing
- paroxetine, duloxetine, fluoxetine or venlafaxine
- Volunteers
- 8,800 people
- Sponsor
- prof. Peter de Jonge
Generalized Anxiety Disorder
Open Trial of an ACT Skills Group and Mobile App for Worry
This study is an open trial of acceptance and commitment therapy (ACT) groups combined with a mobile app for the treatment of Generalized Anxiety Disorder (GAD).
- Trial name
- NCT03709433
- Testing
- ACT groups and mobile app
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Utah State University
Generalized Anxiety Disorder, Chest Pain
Patient-centered Treatment of Anxiety After Low-Risk Chest Pain in the Emergency Room
The goal of this research is to compare the benefits and risks of three anxiety treatments that are pragmatic, graduated in the level of resource intensity, and have demonstrated efficacy and feasibility for real world adoption.
- Conditions
- Generalized Anxiety Disorder, Chest Pain, Panic
- Trial name
- PACER (NCT04811521)
- Testing
- Primary care follow-up, Online Self-Administered Anxiety Management Program plus Peer Support Guidance, Therapist-Administered Cognitive Behavioral Therapy
- Where
- 5 sites in United States
- Volunteers
- 375 people
- Sponsor
- Indiana University
Generalized Anxiety Disorder
A 10-Week Study Evaluating the Efficacy And Safety of PD 0332334 for the Treatment of Generalized Anxiety Disorder
This study will evaluate the efficacy and safety of PD 0332334 for the treatment of generalized anxiety disorder.
- Trial name
- NCT00542685
- Testing
- PD 0332334
- Where
- 43 sites in United States
- Volunteers
- 551 people
- Sponsor
- Pfizer
Generalized Anxiety Disorder
Efficacy of Massage Therapy in the Treatment of Generalized Anxiety Disorder (GAD)
There is an impressive and growing body of data suggesting that massage therapy is effective in decreasing some symptoms of pathological conditions as well as facilitating growth, reducing pain, increasing alertness, diminishing…
- Trial name
- GAD (NCT01337713)
- Testing
- Swedish Massage, Light Touch
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Emory University
Alcoholism, Generalized Anxiety Disorder
Levetiracetam for the Treatment of Alcohol Dependence and Anxiety
The purpose of this study is to determine if levetiracetam is effective in treating alcohol dependence in patients with anxiety symptoms.
- Conditions
- Alcoholism, Generalized Anxiety Disorder, Panic Disorder, Social Phobia
- Trial name
- NCT00141115
- Testing
- levetiracetam
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- New York State Psychiatric Institute
Generalized Anxiety Disorder
Study of Pexacerfont (BMS-562086) in the Treatment of Outpatients With Generalized Anxiety Disorder
The purpose of this study is to learn about the safety and efficacy of pexacerfont in outpatients diagnosed with Generalized Anxiety Disorder
- Trial name
- NCT00481325
- Testing
- pexacerfont, escitalopram
- Where
- 51 sites in United States
- Volunteers
- 260 people
- Sponsor
- Bristol-Myers Squibb
Generalized Anxiety Disorders
Virtual Reality and Relaxation for the Treatment of Generalized Anxiety Disorders: a Comparative Study With Standard Relaxation
The purpose is threefold: Assess the anxiety reduction, the mood positive effect and the rise of quality of life when using methods of relaxation combined with virtual reality with patients suffering from generalized anxiety…
- Trial name
- Relax-TAG (NCT02571790)
- Testing
- Relaxation optimized virtual reality, Classical relaxation (without Virtual Reality)
- Where
- France
- Volunteers
- 58 people
- Sponsor
- Assistance Publique Hopitaux De Marseille