Clinical trials: Generalized Convulsive Status Epilepticus
Generalized Convulsive Status Epilepticus
Ketamine and Levetiracetam as Second-line Antiseizure Medication for Status Epilepticus in Children
About 40% of children with generalized convulsive status epilepticus (GCSE) are not terminated by first-line benzodiazepines (BDZs), and approximately 50% of BDZ-refractory GCSE are not controlled by second-line antiseizure…
- Trial name
- KLaSSEC (NCT07046611)
- Testing
- Ketamine, Levetiracetam
- Where
- Egypt
- Volunteers
- 124 people
- Sponsor
- Sohag University
Generalized Convulsive Status Epilepticus
Combined Ketamine and Midazolam for Generalized Convulsive Status Epilepticus
Generalized convulsive status epilepticus (GCSE) is a common neurological emergency in children. Benzodiazepines are the recommended first line antiseizure medication (ASMs), but they fail to control seizures in a third of cases.
- Trial name
- Ket-Mid (NCT05779657)
- Testing
- Ketamine, Midazolam
- Where
- Egypt
- Volunteers
- 144 people
- Sponsor
- Sohag University
Status Epilepticus, Generalized Convulsive Status Epilepticus
Effectiveness of Combined Levetiracetam and Midazolam in Generalized Convulsive Status Epilepticus in Children
Generalized status epilepticus is a common pediatric neurological emergency with significant mortality and morbidity. Benzodiazepines remain the first anticonvulsive line but benzo-diazepines don't control seizures in about 30%…
- Conditions
- Status Epilepticus, Generalized Convulsive Status Epilepticus, Status Epilepticus, Generalized, Status Epilepticus, Generalized Convulsive
- Trial name
- NCT04926844
- Testing
- Levetiracetam, Midazolam
- Where
- Egypt
- Volunteers
- 144 people
- Sponsor
- Sohag University
Generalized Convulsive Status Epilepticus
Phenobarbital Versus Valproate for Generalized Convulsive Status Epilepticus
Although generalized convulsive status epilepticus (GCSE) is a life-threatening emergency, evidence-based data to guide initial drug treatment choices are lacking in the Chinese population.
- Trial name
- NCT03025906
- Testing
- Phenobarbital, Valproate
- Where
- 6 sites in China
- Volunteers
- 120 people
- Sponsor
- Xuanwu Hospital, Beijing
Generalized Convulsive Status Epilepticus, Intensive Care Unit
Efficacy Study of Intravenous Sodium Valproate in Addition to First Line Anti Epileptic Treatment of Generalized Convulsive Status Epilepticus.
Study Hypothesis Generalized Convulsive Status Epilepticus (GCSE) is a medical emergency associated with an increased morbidity and a prolonged length of hospital stay.
- Trial name
- VALSE (NCT01791868)
- Testing
- Intravenous Sodium Valproate
- Where
- France
- Volunteers
- 245 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris