Clinical trials: Generalized Primary Dystonia
Dystonia, Primary Generalized Dystonia
Bilateral Internal Pallidum Stimulation in Primary Generalized Dystonia
Primary generalized dystonia, also called idiopathic torsion dystonia or dystonia musculorum deformans is a disabling neurological condition which usually starts in childhood, mostly in a lower limb and spreads to other body…
- Trial name
- NCT00272246
- Testing
- deep brain stimulation of the internal globus pallidus
- Where
- Netherlands
- Volunteers
- 24 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Dystonia
Efficacy and Safety of DBS of the GPi in Patients With Primary Generalized and Segmental Dystonia
The purpose of this study is to evaluate the efficacy and safety of bilateral deep brain stimulation of the internal globus pallidus for treating idiopathic generalized or severe segmental dystonia.
- Trial name
- NCT00142259
- Testing
- Deep brain stimulation of the internal globus pallidus
- Where
- 8 sites in Austria, Germany
- Volunteers
- 40 people
- Sponsor
- German Parkinson Study Group (GPS)
Primary Dystonia
Comparison of the Efficacy of Double Monopolar Versus Interleaving Stimulation Modes for Pallidal Deep Brain Stimulation
The aim of the study is to compare the efficacy and the safety profile of the newly introduced interleaving stimulation mode to those of the standard double monopolar stimulation mode during pallidal deep brain stimulation of…
- Trial name
- NCT01497639
- Testing
- Interleaving stimulation mode (Medtronic), Double monopolar stimulation mode (Medtronic)
- Where
- Hungary
- Volunteers
- 34 people
- Sponsor
- University of Pecs
Dystonia
A Study to Evaluate the Efficacy, Safety, and Tolerability of VIM0423 in Individuals With Isolated Dystonia
Stride Dystonia is a randomized, double-blind, placebo-controlled study to evaluate the efficacy, safety, and tolerability of VIM0423 in individuals with isolated dystonia.
- Trial name
- NCT07304089
- Testing
- VIM0423
- Where
- 45 sites in United States, Canada
- Volunteers
- 100 people
- Sponsor
- Vima Therapeutics
Dystonia, Generalized Primary Dystonia
Deep Brain Stimulation for Cervical Dystonia
This study will evaluate the effectiveness of deep brain stimulation (DBS) in treating primary generalized dystonia. Patients with dystonia have muscle spasms that cause uncontrolled twisting and repetitive movement or abnormal…
- Trial name
- NCT00105430
- Testing
- Deep Brain Stimulation
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)