Clinical trials: Generalized Vitiligo
Generalized Vitiligo
Bimatoprost 0.03% Solution With NB-UVB Versus Their Use With Fractional Carbon Dioxide Laser in Treatment of Generalized Vitiligo
Vitiligo is a chronic disorder of pigmentation characterized by the development of white macules on the skin due to loss of epidermal melanocytes.
- Trial name
- NCT03487042
- Testing
- Bimatoprost 0.03% ophthalmic solution
- Volunteers
- 40 people
- Sponsor
- Assiut University
Age-Related Macular Degeneration, Allergies
Tissue Repository Providing Annotated Biospecimens for Approved Investigator-directed Biomedical Research Initiatives
To collect, preserve, and/or distribute annotated biospecimens and associated medical data to institutionally approved, investigator-directed biomedical research to discover and develop new treatments, diagnostics, and…
- Conditions
- Age-Related Macular Degeneration, Allergies, Alpha-Gal Syndrome, Alzheimer Disease
- Trial name
- NCT05635266
- Testing
- Specimen sample
- Where
- United States
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- Sanguine Biosciences
Generalized Vitiligo
Comparing the Efficacy of Visible Light-Ultraviolet A1 Light Versus Narrowband-Ultraviolet B on Generalized Vitiligo
As part of this study, you may have a procedure called phototherapy which involves either VL-UVA or NB-UVB irradiation. NB-UVB phototherapy is not experimental in vitiligo, but use of VL-UVA1 phototherapy in vitiligo is.
- Trial name
- NCT05238077
- Testing
- Visible Light-Ultraviolet A Light or Narrowband-Ultraviolet B phototherapy
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Henry Ford Health System
Vitiligo Vulgaris
The Effect of Fractional Co2 Laser Either With Tacrolimus, Calcipotriol or NB-UVB in Stable Generalized Vitiligo
Vitiligo is an acquired disorder of the skin and mucous membranes characterized by well circumscribed depigmented macules and patches that occur secondary to selective destruction of melanocytes (Zhang et al., 2009).
- Trial name
- NCT03234673
- Testing
- Tacrolimus ointment, calcipotriol ointment, NB-UVB
- Volunteers
- 30 people
- Sponsor
- Assiut University
Vitiligo, Generalized
Comparison of Efficacy and Safety Psoralen Combined With Ultraviolet A (PUVA) Vs Tofacitinib in the Treatment of Generalized Vitiligo.
This study aims to compare the efficacy and safety of PUVA versus Tofacitinib in the treatment of generalized vitiligo. Given the high prevalence of vitiligo in Pakistan and the significant psychosocial impact on patients…
- Trial name
- (PUVA) (NCT07055529)
- Testing
- Group A recieving PUVA therapy, Group B receiving Tablet Tofacitinib
- Where
- Pakistan
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Hayat Abad Medical Complex, Peshawar
Vitiligo, Generalized
Evaluation Safety ,Efficacy Baricitinib Plus Excimer Light Versus Excimer Light Alone in Non Segmental Vitiligo
The study aims to evaluate the safety and efficacy of the combination of topical baricitinib and 308-nm monochromatic excimer light versus 308-nm monochromatic excimer light alone in treatment of non-segmental vitiligo.
- Trial name
- NCT05950542
- Testing
- Baricitinib
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Assiut University
Vitiligo, Generalized
Catecholamines Level in Vitiligo Patients Before and After Excimer Light
Vitiligo is an acquired cutaneous disorder of pigmentation, with a 1-2% incidence worldwide, without predilection for sex or race.
- Trial name
- NCT04803461
- Testing
- serum and urinary catecholamines
- Volunteers
- 21 people
- Sponsor
- Assiut University
Vitiligo, Generalized
Vitiligo Treatment by Targeting TYK2 Mediated Responses
Vitiligo affects approximately 1 to 2% of the global population and significantly impacts people's quality of life. Achieving the best treatment outcomes for vitiligo involves addressing the autoimmune inflammatory response to…
- Trial name
- ViTYK (NCT06327321)
- Testing
- Deucravacitinib, Volunteer without treatment
- Where
- 5 sites in France
- Volunteers
- 128 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Vitiligo
Resident Memory T Cells in Vitiligo
This study aims to detect the presence and diversity of Tissue resident memory T cell populations in early and late cases of generalized non-segmental Vitiligo.
- Trial name
- NCT05223738
- Where
- Egypt
- Volunteers
- 29 people
- Sponsor
- Kasr El Aini Hospital
Vitiligo
Repigmentation of Stable Vitiligo Lesions Using Spray-On Skin™ Cells
To evaluate repigmentation and quality of life after treatment of stable vitiligo lesions using the RECELL Device.
- Trial name
- TONE (NCT05971381)
- Testing
- RECELL® Autologous Cell Harvesting Device
- Where
- 17 sites in United States
- Volunteers
- 109 people
- Sponsor
- Avita Medical
Vitiligo, Vitiligo, Generalized
Oral Vitamin D Supplementation Combined With Phototherapy as a Treatment for Vitiligo
A randomized clinical trial that treats vitiligo patients with oral vitamin D and Narrow-Band Ultraviolet B (NB-UVB) phototherapy (intervention group); or placebo and NB-UVB phototherapy (control group).
- Conditions
- Vitiligo, Vitiligo, Generalized, Autoimmune, Autoimmune Diseases
- Trial name
- NCT04872257
- Testing
- Oral Vitamin D, NB-UVB Phototherapy
- Where
- Mexico
- Volunteers
- 26 people
- Sponsor
- Hospital Universitario Dr. Jose E. Gonzalez
Vitiligo
Clinical Trial of Simvastatin to Treat Generalized Vitiligo
The investigators purpose is to initiate a phase II, randomized, placebo-controlled clinical trial to test simvastatin, an FDA-approved medication for hypercholesterolemia, as a new treatment for vitiligo.
- Trial name
- NCT01517893
- Testing
- Simvastatin
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- John Harris
Vitiligo, Generalized
Autologous Cellular Graft in Surgical Treatment of Vitiligo
This is a double blinded self controlled randomized trial to assess Autologous Micro Cellular Grafts in surgical treatment of stable resistant vitiligo.
- Trial name
- NCT05503368
- Testing
- surgical treatment of vitiligo using NCES
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Cairo University
Vitiligo, Generalized
Gasdermin D Expression in Generalized Vitiligo Patients After Narrow-band Ultraviolet B Therapy
The aim of this study is to: 1. Evaluate the role of tissue Gasdermin D expression using immunehistochemstry techniques in patients with generalized vitiligo and compare it with healthy controls. 2.
- Trial name
- NCT06546059
- Testing
- narrow band ultraviolet-B
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- South Valley University
Vitiligo, Generalized
Phototherapy Combination With Topicals in Vitiligo
Patients will be included in a randomized controlled clinical trial, will enroll only adult vitiligo patients with surface area of at least 10% who are being followed in the outpatient dermatology clinics of King Abdullah…
- Trial name
- NBUVB (NCT04440371)
- Testing
- Tacrolimus 0.1% ointment twice daily plus NBUVB 3 times weekly, Calcipotriol/Betamethasone ointment plus NBUVB
- Where
- Jordan
- Volunteers
- 40 people
- Sponsor
- Jordan University of Science and Technology
Vitiligo, Generalized
Vitiligo, New Treatment and Serum s100B
vitiligo is an autoimmune depigmenting skin disorder characterized by milky white macules or patches, with 2% worldwide prevalence.
- Trial name
- NCT06768840
- Testing
- Baricitinib, oral mini pulse, Narrow Band UVB Treatment
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- South Valley University