Clinical trials: Genetic Linkage
A Multilevel, Tailored COVID-19 Testing Condition, A Nontailored COVID-19 Testing Control Condition
A Faithful Response to COVID-19 Project
This 2-arm clustered, randomized community trial will test a multilevel, COVID-19 testing and linkage to care (eg, health insurance, medical appointments, community resources, contact tracing) intervention against a nontailored…
- Trial name
- FR (NCT04978207)
- Testing
- A Faithful Response to COVID-19
- Where
- 10 sites in United States
- Volunteers
- 1,013 people, healthy volunteers welcome
- Sponsor
- University of Missouri, Kansas City
Developmental Articulation Disorder, Speech Disorder
Characteristics of Idiopathic Familial Speech Disorders
According to studies, speech disorders with unknown causes (idiopathic) affect approximately 5% of the population at some point in their life.
- Conditions
- Developmental Articulation Disorder, Speech Disorder, Stuttering
- Trial name
- NCT00001551
- Where
- 2 sites in United States
- Volunteers
- 375 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Family's Connection to Community Resources and Public Benefits, Caregiver Satisfaction and Connectedness to Clinic
Community to Clinic Linkage Program at SFGH
It is increasingly clear that the environment in which a child lives, plays, and goes to school has a significant impact on their health.
- Conditions
- Family's Connection to Community Resources and Public Benefits, Caregiver Satisfaction and Connectedness to Clinic, Child Health Care Status
- Trial name
- CCLiP@SFGH (NCT01939704)
- Testing
- Pediatric Primary Care Intervention, Pediatric Urgent Care Intervention
- Where
- United States
- Volunteers
- 1,809 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Emergency Services, Psychiatric
Emergency Linkage to Outpatient Psychiatric Services
The purpose of this study is to compare two different kinds of follow-up care and their effects on psychiatric service use and psychological well-being.
- Trial name
- NCT00278811
- Testing
- mobile crisis team
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of Rochester
Cardiovascular Diseases, Heart Diseases
Segregation/Linkage Analysis for Hypertension
To determine the genetic components of hypertension using a series of simulation experiments designed to determine the power and validity of the then recently developed methods of segregation and linkage analysis.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Hypertension
- Trial name
- NCT00005158
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
HIV, Linkage to Care
Kingasa Pilot Study
In the Kingasa study, the investigators will use a factorial design in order to evaluate both an intervention to increase male partner HIV testing and an intervention for pregnant and postpartum women living with HIV to provide…
- Conditions
- HIV, Linkage to Care, PMTCT, PrEP
- Trial name
- NCT05092997
- Testing
- POC viral load testing, Wellness visit services for male partners
- Where
- Uganda
- Volunteers
- 151 people, healthy volunteers welcome
- Sponsor
- University of Washington
Hypertension, High Blood Pressure
Optimizing Linkage and Retention to Hypertension Care in Rural Kenya
Cardiovascular disease (CVD) is the leading cause of death in sub-Saharan Africa among adults above age 30. The prevalence of hypertension, a major risk factor for CVD, is increasing over time in sub-Saharan Africa, exerting a…
- Trial name
- NCT01844596
- Testing
- behavioral communication strategy, Behavioral communication strategy, plus smartphone-based tool
- Where
- Kenya
- Volunteers
- 1,455 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Emergency and Urgent Care Pathways
Connected Yorkshire: A Data-linkage Study of Pre-hospital, Emergency Department and Out of Hours Service Data
There is increased demand on emergency departments (ED) across the UK. The services are becoming stretched and as a result waiting times are increasing and patient care is suffering.
- Trial name
- NCT03482271
- Testing
- No intervention - data collection only
- Volunteers
- 7,500,000 people
- Sponsor
- University of Sheffield
Hepatitis B
Healthy Planet Hepatitis B
This quality improvement project utilizes Epic Health Planet to increase screening for chronic hepatitis B through the creation of registries and ordering of hepatitis B laboratory panels.
- Trial name
- NCT04503993
- Testing
- Hepatitis B surface antigen, Hepatitis B core antibody, and Hepatitis B surface antibody
- Where
- United States
- Volunteers
- 5,004 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Hepatitis C, Chronic
Hepatitis C Surveillance With Linkage to Care of Patients From Non-ID Departments in Jiangsu
Due to the occult nature of hepatitis C virus (HCV), it is estimated that less than 5% of people with chronic hepatitis C (CHC) infection knowing their status.
- Trial name
- NCT03772002
- Testing
- HCV screening
- Where
- 2 sites in China
- Volunteers
- 600 people
- Sponsor
- The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Brain Tumor, Glioma
Gliogene: Brain Tumor Linkage Study
The goal of this research study is to investigate the role of genes that may point to a higher risk of developing a glioma. Researchers will use new gene mapping techniques to study how high-risk factors are passed on through a…
- Trial name
- NCT00418899
- Testing
- Questionnaire
- Where
- 15 sites in United States, Denmark and 4 more
- Volunteers
- 17,080 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
HIV (Human Immunodeficiency Virus)
Link4Health: A Combination Strategy for Linkage and Retention, Swaziland
Despite increased HIV (Human Immunodeficiency Virus) infection testing in Africa, many patients never enroll in subsequent HIV care after testing or remain in care after an initial enrollment.
- Trial name
- L4H (NCT01904994)
- Testing
- POC (point-of-care) CD4+ (cluster of differentiation 4) Count, Accelerated ART (antiretroviral therapy) Initiation, Basic Care and Prevention Package
- Where
- 20 sites in Eswatini
- Volunteers
- 2,201 people
- Sponsor
- Columbia University
Pain, Postoperative, Anaplasia
the Effect of Doctor-nurse-patient Cooperative Analgesic Linkage Program on Movement Evoked Pain
1. To establish doctor-nurse-patient cooperative analgesic linkage program. 2. Evaluate the effect of doctor-nurse-patient cooperative analgesic linkage program on movement evoked pain after laparotomy for patients with…
- Trial name
- NCT03823846
- Testing
- Routine Dezocine injection, Adjusted Dezocine injection, Routine Dynastat or Flurbiprofen Axetil jinjection
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Genetic Linkage, Myelofibrosis
Genetic Analysis of Gray Platelet Syndrome
This study will identify and characterize the gene or genes responsible for Gray Platelet syndrome (GPS). Platelets are small blood cells that stick on injured blood vessels to form a plug and stop bleeding.
- Trial name
- NCT00069680
- Where
- United States
- Volunteers
- 123 people
- Sponsor
- National Human Genome Research Institute (NHGRI)
Human Immunodeficiency Virus
Jamii Bora: A Home-Based Couples Intervention
The purpose of the study is to develop and pilot-test a home-based intervention to facilitate sate HIV testing and disclosure within pregnant couples in order to increase use of prevention-of-mother-to-child-transmission (PMTCT)…
- Trial name
- NCT02403583
- Testing
- Intervention- Home Visits
- Where
- 5 sites in Kenya
- Volunteers
- 233 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Contraception, Pharmaceutical Services
Hormonal Contraception Access Through Pharmacist Prescribing Implementation
The goal of this clinical trial is to learn if use of the HAPPI software can improve pharmacist-provided birth control services. The main questions it aims to answer are: 1.
- Conditions
- Contraception, Pharmaceutical Services, Access and Linkage to Healthcare, Technology Use
- Trial name
- HAPPI (NCT06823037)
- Testing
- HAPPI software
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- EMPOWERX INC
HIV Infections
Improving HIV Diagnosis, Linkage to Care, and Prevention Services With HIV Point-of-Care Nucleic Acid Tests
This project (NCT04880200) will develop, implement, and evaluate models for use of point-of-care nucleic acid testing (POC NAT) among HIV-negative persons seeking HIV testing, PEP, and PrEP and HIV-positive persons in community…
- Trial name
- GAIN (NCT04880200)
- Testing
- POC NAT & Adherence Intervention
- Where
- United States
- Volunteers
- 194 people
- Sponsor
- University of Washington
Emergency Medicine
Text-Enabled Ascertainment and Community Linkage for Health
The goal of this study is to pilot test a novel tool for health related social needs screening and linkage to community resources in the ED by randomizing participants to standard handout v.
- Trial name
- TEACH (NCT04058301)
- Testing
- Text message information
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Massachusetts General Hospital
Substance Abuse
Reducing Barriers to Drug Abuse Treatment Services
The broad goal of this study is to assess the effectiveness of two interventions to facilitate treatment linkage and treatment engagement.
- Trial name
- RBP (NCT00273845)
- Testing
- Motivational interviewing, Strengths-Based Case Management
- Where
- United States
- Volunteers
- 678 people
- Sponsor
- Wright State University
HIV
Enhanced Linkage to HIV Care Following Home-Based HIV Testing in Rural Uganda
The purpose of this study is to evaluate the effectiveness of a linkage to care intervention at achieving HIV viral suppression and intermediate outcomes of linkage/time to care, time to /receipt of opportunistic infection…
- Trial name
- NCT02545673
- Testing
- Enhanced linkage to care, Standard-of-care plus
- Where
- Uganda
- Volunteers
- 567 people
- Sponsor
- Susan M Kiene