Clinical trials: Genital Diseases, Female
Endometriosis, Fibroids
Evaluating Tibolone Add-back in Patients With Endometriosis and Fibroids
While there are many medical options for managing endometriosis and fibroids, GnRH-agonist (GnRH-a) therapy remains a very common method of treating these complex conditions.
- Trial name
- eTAPE (NCT05568940)
- Testing
- Tibolone 2.5 Mg Oral Tablet
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Endometriosis
A Randomized Open Label Study of KLH-2109 in Patients With Endometriosis(1)
The purpose of this study is to evaluate the efficacy and safety of KLH-2109 in patients with endometriosis.
- Trial name
- NCT01395940
- Testing
- KLH-2109
- Where
- Japan
- Volunteers
- 20 people
- Sponsor
- Kissei Pharmaceutical Co., Ltd.
Breast Cancer, Transcriptomes
Transcriptomes Breast, Ovarian and Leukocyte Hereditary Genes Predisposing to Breast and / or Ovarian Cancer
This is a case-control study of molecular diagnostics. This study requires two steps: The first part of the study will be conducted on a population of 20 women without breast cancer and, or ovarian family (Healthy Volunteers…
- Conditions
- Breast Cancer, Transcriptomes, Molecular Diagnostic, Ovarian Cancer
- Trial name
- CASOHAR (NCT02560818)
- Testing
- collection of a blood sample and breast and ovarian tissue, use of a previous blood collection for patients
- Where
- France
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Centre Francois Baclesse
HIV Infections
Pharmacokinetics of Raltegravir During Third Trimester Pregnancy and Post-Partum
This study will evaluate the pharmacokinetic disposition of raltegravir in pregnant HIV-1 infected women. These results will be compared to pharmacokinetic data obtained following pregnancy as well as to studies previously…
- Trial name
- NCT00689910
- Where
- 4 sites in United States
- Sponsor
- University of California, San Francisco
Hiv, Transgenderism
Microeconomic Intervention to Reduce HIV Transmission in Economically Disadvantaged Transgender Women
The purpose of this research study is to learn more about the economic situations, discrimination experiences, and risk behaviors of transgender women.
- Trial name
- NCT04275310
- Testing
- Microeconomic Intervention
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Uterine Cancer
A Retrospective Study on Multiple Classifier Endometrial Cancer
Endometrial cancer is not a single entity but rather a very heterogeneous group of diseases. Historically, endometrial cancer patients have been classified as endometrioid (type I) or non-endometrioid (type II) according to the…
- Trial name
- NCT05976113
- Testing
- Observation only
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- Fondazione IRCCS Istituto Nazionale dei Tumori, Milano
Primary Ovarian Insufficiency
Ovarian Laparoscopic In Vivo Activation of Ovary for Premature Ovarian Insufficiency
The OLIVA device will enable to perform shallow slashes on the ovarian cortex in patients undergoing oophorectomy. Prior to the resection of the ovary from the pedicle we will perform 5 parallel slashes 3 cm long.
- Trial name
- OLIVA (NCT03034616)
- Testing
- OLIVA device
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Carcinoma Cervix
Concurrent Chemoradiotherapy With Weekly Cisplatin Versus Concurrent Chemoradiotherapy With Weekly Cisplatin and Paclitaxel in Locally Advanced Carcinoma Cervix
The purpose of this study is to check whether addition of paclitaxel to cisplatin and radiation therapy will improve the outcome in locally advanced carcinoma cervix.
- Trial name
- NCT01593306
- Testing
- Paclitaxel, Cisplatin, Cisplatin
- Where
- India
- Volunteers
- 80 people
- Sponsor
- Indira Gandhi Medical College, Shimla
Cervical Cancer, Ovarian Cancer
Clinical Study on the Safety, Pharmacokinetics, and Efficacy of ScTIL (Genetically Modified Tumor Infiltrating Lymphocytes) in the Treatment of Gynecological Malignancies
The purpose of this study is to evaluate the safety and clinical efficacy of ScTIL in the treatment of recurrent or refractory cervical cancer, ovarian cancer and malignant trophoblastic tumor, to evaluate the pharmacokinetic…
- Conditions
- Cervical Cancer, Ovarian Cancer, Malignant Trophoblastic Tumor
- Trial name
- NCT05342506
- Testing
- Toripalimab + ScTIL
- Volunteers
- 30 people
- Sponsor
- Peking Union Medical College Hospital
Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage IA Breast Cancer AJCC v8
Social Health, Activity Behaviors, and Quality of Life Among Young Adult Cancer Survivors
This longitudinal observational study examines how social health, including social support, social roles, loneliness, social anxiety, and social network characteristics, relates to physical activity, sedentary time, and quality…
- Conditions
- Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage IA Breast Cancer AJCC v8, Anatomic Stage IB Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8
- Trial name
- NCT07259304
- Testing
- Medical Device Usage and Evaluation, Quality-of-Life Assessment, Survey Administration
- Where
- 3 sites in United States
- Volunteers
- 173 people
- Sponsor
- University of Southern California
Fallopian Tube Cancer, Ovarian Cancer
Irofulven in Treating Patients With Recurrent or Persistent Ovarian, Fallopian Tube, or Peritoneal Cancer
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. PURPOSE: Phase II trial to study the effectiveness of irofulven in treating patients who have recurrent or…
- Conditions
- Fallopian Tube Cancer, Ovarian Cancer, Primary Peritoneal Cavity Cancer
- Trial name
- NCT00019552
- Testing
- irofulven
- Where
- United States
- Sponsor
- National Cancer Institute (NCI)
Ovary Cyst
Are the Combined Oral Contraceptive Pills Needed for Management of the Simple Ovarian Cysts in Reproductive Women?
Women will be managed by either of the two modalities and will be followed up by transvaginal ultrasound monthly for three successive months to evaluate the size and location of the functional ovarian cyst (follicular), to…
- Trial name
- NCT03357640
- Testing
- combined oral contraceptive pills
- Where
- Egypt
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Benha University
Urinary Incontinence,Stress, Stress Urinary Incontinence
Synchronized Core-Pelvic Floor Activation in Urinary Incontinence
This study aims to investigate whether co-activation of the pelvic floor and core muscles improves treatment outcomes in individuals with urinary incontinence.
- Conditions
- Urinary Incontinence,Stress, Stress Urinary Incontinence, Mixed Incontinence Due to Prolapse of Female Genital Organ, Urinary Incontinence
- Trial name
- NCT07387640
- Testing
- Conventional Pelvic Floor Muscle Training, Pelvic Floor and Core Muscle Co-activation Training
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Bezmialem Vakif University
Endometrial Carcinoma, Neoplasms, Endometrial
Two Part (Phase1b/ Phase3) Trial of Subcutaneous Dostarlimab Plus Carboplatin-Paclitaxel in Participants With Primary Advanced or Recurrent Endometrial Cancer
This is an open-label study, meaning both the researchers and participants will know which treatment is being given. The study has two parts. In Part 1, researchers will identify the most suitable SC dose.
- Trial name
- SAPPHIRE (NCT07860450)
- Testing
- Dostarlimab, Carboplatin and paclitaxel
- Volunteers
- 378 people
- Sponsor
- GlaxoSmithKline
Sub Fertility, Female, Fertility Disorders
Effects of Fasting on Success Rates of Assisted Reproductive Techologies
This exploratory study investigates fasting as a potential supportive therapy for infertility treatment in women undergoing in-vitro-fertilization (IVF) / intracystoplamsatic sperm injection (ICSI)
- Conditions
- Sub Fertility, Female, Fertility Disorders, Fertility Issues, Sub-fertility
- Trial name
- KiWuC (NCT04998591)
- Testing
- Fasting
- Where
- Germany
- Volunteers
- 1 people
- Sponsor
- Charite University, Berlin, Germany
Polycystic Ovary Syndrome
Study of Pharmacodynamics of LIK066 in Overweight and Obese Women With Polycystic Ovary Syndrome
The purpose of the study was to evaluate whether LIK066 can be developed for the treatment of polycystic ovary syndrome (PCOS) in overweight and obese women.
- Trial name
- PCOS (NCT03152591)
- Testing
- LIK066
- Where
- 5 sites in United States, Germany
- Volunteers
- 29 people
- Sponsor
- Novartis Pharmaceuticals
Ovarian Cancer, Primary Peritoneal Cancer
Dose-Escalation Study of Intraperitoneal (IP) Cisplatin, IV/IP Paclitaxel, IV Bevacizumab, and Oral Olaparib for Newly Diagnosed Ovarian, Primary Peritoneal, and Fallopian Tube Cancer
The purpose of this study is to test the safety of the drug olaparib at different dose levels. It will be given with the standard initial chemotherapy for cancer as well as a drug called bevacizumab.
- Conditions
- Ovarian Cancer, Primary Peritoneal Cancer, Fallopian Tube Cancer
- Trial name
- NCT02121990
- Testing
- Paclitaxel,, Bevacizumab, Cisplatin
- Where
- 5 sites in United States
- Volunteers
- 17 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Cervical Adenosarcoma
Surgical Handling of Fertility-preserving Treatments for Cervical Adenocarcinomas
Despite a growing body of literature on the subject, there is still uncertainty regarding direct comparisons between different conservative surgical techniques for cervical adenocarcinomas.
- Trial name
- SHAFT (NCT07394413)
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Premature Ovarian Insufficiency, Ovarian Reserve Function
Therapeutic Effect of Vitamin C Supplementation in Patients With Ovarian Aging
The goal of this clinical trial is to learn if Vitamin C works to improve ovarian reserve in women with ovarian aging. It will also learn about the safety of Vitamin C.
- Trial name
- NCT06794060
- Testing
- Vitamin C (Ascorbic Acid)
- Volunteers
- 354 people
- Sponsor
- Peking University Third Hospital
Endometrioma
Suture of the Ovary After Enucleation of Ovarian Endometrioma
Endometriosis is an estrogen-dependent chronic disease, characterized by the presence of ectopic endometrial-like tissue outside the uterine cavity.
- Trial name
- SOAVE-1 (NCT03788720)
- Testing
- Suture of the ovarian cortex, No suture of the ovarian cortex
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Università degli Studi dell'Insubria
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.