Clinical trials: Genital Diseases, Female
Genital Diseases, Female, Ectopic Pregnancy
Randomized Study of a Dematerialized Management for Post-Emergency Gynecological Follow-Up
The GYNAB study aims to compare patient satisfaction and clinical outcomes between dematerialized post-emergency gynecological follow-up using a connected health app and traditional in-person follow-up. Conducted by Drs.
- Conditions
- Genital Diseases, Female, Ectopic Pregnancy, Uncertain Viability of Pregnancy, Abortion, Missed
- Trial name
- GYNAB (NCT06615843)
- Testing
- Participants will receive post-emergency gynecological follow-up at home using a connected health app
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Cervical Cancer
Ocular Assessments in Patients Treated With Tivdak® in Recurrent or Metastatic Cervical Cancer
TIVDAK is used for the treatment of cervical cancer that has come back after chemotherapy. Chemotherapy is a treatment that uses medicines to stop the growth of cancer cells.
- Trial name
- NCT06952660
- Testing
- TIVDAK
- Where
- 132 sites in United States, Puerto Rico
- Volunteers
- 100 people
- Sponsor
- Pfizer
Educational Problems, Surgery
Standardized Educational Videos of Laparoscopic Gynecological Surgeries
Owing to coronavirus disease-related social distancing requirements, online education has gained prominence. Surgical trainers consider online videos as a useful teaching aid that maximizes trainees' learning and skill…
- Conditions
- Educational Problems, Surgery, LAP, GYN Disorders
- Trial name
- AA-GYNLAP (NCT05227430)
- Testing
- Educational video tutorials
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Gynecologic Disease
ERAS Versus Conventional Care Following Gynecological Laparoscopic Surgery
This prospective randomized comparative study aims to compare Enhanced Recovery After Surgery (ERAS) protocol versus conventional perioperative care in women undergoing benign gynecological laparoscopic surgery.
- Trial name
- NCT07832838
- Testing
- Enhanced Recovery After Surgery Protocol, Conventional Perioperative Care
- Volunteers
- 100 people
- Sponsor
- Assiut University
GYN Disorders
GENERATE - Next GENERATion of GynEcological Surgery - Robotic Assisted Surgery in Gynecological Indications
GENERATE - Next GENERATion of GynEcological Surgery - Robotic Assisted Surgery in Gynecological Indications Generate real-world evidence in the use of the da Vinci Surgical Systems for gynecological indications within the German…
- Trial name
- GENERATE (NCT05867927)
- Testing
- Robotic-assisted surgery (da Vinci), Non-da Vinci Surgery
- Where
- 15 sites in Germany
- Volunteers
- 1,250 people
- Sponsor
- Intuitive Surgical
Muscle Loss, Extracellular Fluid Alteration
Ultrasound Detection of Body Composition in Critical Care
Objective assessment of the Changes in body composition of critically ill patients is very valuable. Ultrasound stands as a solution due to its portability, bedside availability, and radiation-free technology.
- Conditions
- Muscle Loss, Extracellular Fluid Alteration, Critical Illness, Pregnancy Complications
- Trial name
- NCT06728722
- Testing
- ultrasound detection of body composition
- Where
- Egypt
- Volunteers
- 121 people
- Sponsor
- Ain Shams University
Carcinoma, Ovarian Epithelial, Ovarian Neoplasms
AB-1015, an Integrated Circuit T (ICT) Cell Therapy in Patients With Platinum Resistant Epithelial Ovarian Cancer
This is a multi-center, open-label phase 1 dose escalation trial that uses a modified 3+3 design to identify a recommended phase 2 dose (RP2D) of AB-1015 cell product.
- Conditions
- Carcinoma, Ovarian Epithelial, Ovarian Neoplasms, Fallopian Tube Neoplasms, Peritoneal Neoplasms
- Trial name
- NCT05617755
- Testing
- AB-1015
- Where
- 8 sites in United States
- Volunteers
- 19 people
- Sponsor
- Arsenal Biosciences, Inc.
Digestive System Disease, Urologic Diseases
Low-dose Droperidol for Prevention of Postoperative Delirium in Elderly Patients After Non-cardiac Surgery
The aim of this multicenter, prospective, randomized, double-blind and large sample study is to explore the preventive effect of low-dose droperidol on POD in elderly patients after non-cardiac surgery, providing new approach for…
- Conditions
- Digestive System Disease, Urologic Diseases, Gynecological Disease, Orthopedic Surgery
- Trial name
- NCT05401058
- Testing
- Droperidol Injection, Saline
- Where
- 9 sites in China
- Volunteers
- 797 people
- Sponsor
- RenJi Hospital
Enhanced Recovery After Surgery, Gynecologic Disease
ERAS in Pediatric & Adolescent Gynecology Preoperative Counseling
The Investigator propose a randomized trial that will assess whether participant involvement in pre-operative counseling for ERAS improves post-surgical pain scores.
- Trial name
- NCT04963751
- Testing
- Enhanced Recovery After Surgery (ERAS) Counseling to Patients, Enhanced Recovery After Surgery (ERAS) Counseling to Caregiver
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Colorado, Denver
Advanced Solid Tumors, Genital Neoplasm, Female
A Study of a Selective T Cell Receptor (TCR) Targeting, Bifunctional Antibody-fusion Molecule STAR0602 in Participants With Advanced Solid Tumors
This is an open label, multicenter, phase 1/2 study to assess the safety/tolerability and preliminary clinical activity of STAR0602 as a single agent and in combination with chemotherapy administered intravenously in participants…
- Conditions
- Advanced Solid Tumors, Genital Neoplasm, Female, Urogenital Neoplasms, Lung Neoplasm
- Trial name
- START-001 (NCT05592626)
- Testing
- STAR0602, Irinotecan (Camptosar), Docetaxel (Taxotere)
- Where
- 19 sites in United States, Canada and 2 more
- Volunteers
- 366 people
- Sponsor
- Marengo Therapeutics, Inc.
Gynecologic Disease
Bowel Preparation in Minimally Invasive Gynecologic Surgery
This is a prospective randomized study of patients who are scheduled to undergo minimally invasive robotic gynecologic surgery. Patients will be randomized to require either pre-surgical bowel preparation vs.
- Trial name
- NCT06820359
- Testing
- Bowel Preparation, No bowel preparation
- Where
- 2 sites in United States
- Sponsor
- Henry Ford Health System
Advanced Solid Tumors, Breast Cancer
A Phase 1 Study of ATV-1601 in Patients With Advanced Cancer That Have AKT1 E17K Mutations
This is a Phase 1, open-label study to evaluate the safety and tolerability of ATV-1601 administered orally in adults with AKT1 E17K-mutant, advanced solid tumors and also in HR+/HER2- advanced and metastatic breast cancer, with…
- Conditions
- Advanced Solid Tumors, Breast Cancer, Breast Carcinoma, Breast Neoplasms
- Trial name
- NCT07038369
- Testing
- ATV-1601, ATV-1601 + Fulvestrant
- Where
- 8 sites in United States, France and 2 more
- Volunteers
- 134 people
- Sponsor
- Atavistik Bio, Inc
Gynecologic Disease
GYN-AIDE: Gynecologic Oncology Navigation Through AI-Driven Education
This study seeks to understand how endometrial cancer patients get medical information about cancer care and their satisfaction with those health-seeking methods.
- Trial name
- NCT07279571
- Testing
- Non-Interventional Study
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- University of Southern California
Bacterial Infections, Bacterial Infections and Mycoses
Large Algorithm Setting and Validation Study
In this pilot study, prospectively acquired clinician-collected and participant-collected vaginal swab specimens will be obtained from up to 1000 individuals with signs and symptoms of vaginitis to develop and validate a…
- Conditions
- Bacterial Infections, Bacterial Infections and Mycoses, Infections, Vaginitis
- Trial name
- LAVA (NCT07607470)
- Testing
- Nanopath Vaginitis Assay, BD Max™ Vaginal Panel, Cepheid Xpert® Xpress MVP
- Where
- 2 sites in United States
- Volunteers
- 1,000 people
- Sponsor
- Nanopath, Inc
Pelvic Pain, Endometriosis
Glycemic Regulation as Endometriosis Adjunct Treatment
The goal of this pilot trial is to learn if a novel non-hormonal treatment, metformin hydrochloride, works to treat pelvic pain in young women with endometriosis.
- Trial name
- GREAT (NCT06611501)
- Testing
- Metformin Hydrochloride
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Boston Children's Hospital
Ovarian Cancer, Fallopian Tube Cancer
Relacorilant in Combination With Different Treatment Regimens in Patients With Gynecological Cancers
This is a Phase 2, open-label, global, multi-arm study to evaluate efficacy and safety of relacorilant in combination with other treatments in patients with gynecological cancers.
- Conditions
- Ovarian Cancer, Fallopian Tube Cancer, Peritoneal Neoplasms, Endometrial Cancer
- Trial name
- NCT06906341
- Testing
- Relacorilant 150 mg once daily (QD), Nab-paclitaxel 80 mg/m^2, Bevacizumab 10 mg/kg
- Where
- 49 sites in United States, Belgium and 6 more
- Volunteers
- 270 people
- Sponsor
- Corcept Therapeutics
Surgery, Gynecologic Disease
Study Evaluating the Success Rate of Outpatient Management of the Total Benign Hysterectomy by Transvaginal Natural Orifice Transluminal Endoscopic Surgery (vNOTES) Compared to Each of the Two Laparoscopic Routes (Conventional and Robot-assisted).
Benign total hysterectomy is one of the most commonly performed gynecological surgery. Conventionally performed by a classical surgical approach, it is now provided routinely and for several years by laparoscopy and more recently…
- Trial name
- HYSTERAMBU (NCT06471049)
- Testing
- Benign Hysterectomy
- Where
- France
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Elsan
DSD, Hypospadias
Breaking Silence Through Story: A Narrative Medicine Intervention for Parents of Children With Urogenital Conditions
The goal of this clinical trial is to learn whether a journaling intervention can reduce stress and anxiety in parents of children with urogenital conditions (such as differences of sex development and hypospadias).
- Trial name
- NCT06989593
- Testing
- Narrative Medicine Journaling Intervention
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Sarah Schlegel
Gynecologic Disease
Comparative Study of Blood Loss in Total Laparoscopic Hysterectomy by Ligation the Uterine Arteries in Different Techniques.
Following Caesarean section, hysterectomy is the second most common major gynecological surgery, with approximately 600,000 procedures performed annually in the USA. Since Reich et al.
- Trial name
- NCT06875518
- Testing
- BTLH with bilateral uterine artery ligation from its origin, Conventional TLH
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Mostafa Bahaa
Gynecologic Cancer, Gynecologic Neoplasm
The Lifestyle and Empowerment Techniques in Survivorship of Gynecologic Oncology Study
This study compares traditional follow-up of gynaecological cancer patients to an alternative follow-up model. In the alternative follow-up model the patients will meet a nurse at every second consultation.
- Conditions
- Gynecologic Cancer, Gynecologic Neoplasm, Ovarian Cancer, Endometrial Cancer
- Trial name
- LETSGO (NCT04122235)
- Testing
- LETSGO follow-up
- Where
- 12 sites in Norway
- Volunteers
- 755 people
- Sponsor
- Sorlandet Hospital HF