Clinical trials: Genital Diseases, Female
HPV, High-risk HPV (Any Strain)
Study Assessing Reduced HPV Infectivity and Transmission in HPV-Positive Women Following Vaccination With 9vHPV
This is a randomized, open-label trial, to assess whether a single dose of HPV nonavalent vaccine, administered to HIV uninfected, unvaccinated women with high risk HPV16/18/31/33/45/52 or 58 can decrease the infectivity of shed…
- Conditions
- HPV, High-risk HPV (Any Strain), Human Papillomavirus (HPV) Infections
- Trial name
- RIFT-SSA (NCT07303751)
- Testing
- Nonavalent HPV vaccine (9vHPV)
- Where
- Sierra Leone
- Volunteers
- 80 people
- Sponsor
- Institut d'Investigació Biomèdica de Bellvitge
Uterine Cervical Neoplasms
Detection of Minimal Residual Disease Based on HPV ctDNA in Cervical Cancer
In this study, a large-scale cohort of cervical cancer patients was established in multiple centers. Minimal residual disease(MRD) was assessed by ddPCR detection of HPV E7 gene ctDNA to assess tumor burden and predict the risk…
- Trial name
- NCT05531981
- Testing
- detect HPV E7 ctDNA
- Where
- China
- Volunteers
- 350 people
- Sponsor
- Peking Union Medical College Hospital
Advanced Malignant Neoplasm, Cervical Squamous Cell Carcinoma
Nanoparticle Albumin-Bound Rapamycin in Treating Patients With Advanced Cancer With mTOR Mutations
This pilot trial studies how well nanoparticle albumin-bound rapamycin works in treating patients with cancer that as has spread to other places in the body and usually cannot be cured or controlled with treatment (advanced…
- Conditions
- Advanced Malignant Neoplasm, Cervical Squamous Cell Carcinoma, Endometrial Carcinoma, Malignant Uterine Neoplasm
- Trial name
- NCT02646319
- Testing
- Laboratory Biomarker Analysis, Nanoparticle Albumin-Bound Rapamycin, Quality-of-Life Assessment
- Where
- 2 sites in United States
- Volunteers
- 2 people
- Sponsor
- Mayo Clinic
Sexual Dysfunction, Bipolar Disorder
Study of Maca Root to Treat Sexual Dysfunction Associated With the Treatment Regimen for Bipolar Disorder in Females
The purpose of this research study is to find out whether Maca Root is effective for treating sexual dysfunction in females that is caused by the treatment for bipolar disorder.
- Trial name
- NCT00575328
- Testing
- Maca Root
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Massachusetts General Hospital
Ovarian Cancer
Secondary Cytoreductive Surgery After Chemotherapy for Recurrent Epithelial Ovarian Cancer
To compare outcomes between the CRS group and the control group in patients with recurrent epithelial ovarian cancer who have undergone chemotherapy
- Trial name
- KOV-02S (NCT07171528)
- Testing
- Secondary Cytoreductive Surgery
- Where
- South Korea
- Volunteers
- 80 people
- Sponsor
- National Cancer Center, Korea
Vulva Cancer, Vulva Neoplasm
Danish Vulva Cancer Recurrence Study
The overall aim is to investigate different aspects of recurrence detection in women with vulva cancer (VC) to identify optimal treatment- and surveillance programs.
- Conditions
- Vulva Cancer, Vulva Neoplasm, Vulvar Cancer, Vulva Disease
- Trial name
- DaVulvaRec (NCT06495554)
- Testing
- Measurement of circulating tumor-DNA, Collection of patient-reported outcomes, Algorithmically determined telephone interview with a nurse
- Where
- 2 sites in Denmark
- Volunteers
- 1,295 people
- Sponsor
- University of Aarhus
Polycystic Ovary Syndrome
Use of Myo-inositol as Adjuvant Therapy in Patients With Polycystic Ovary Syndrome (PCOS) in Vitro Fertilization (IVF)
The original mechanism of action of myo-inositol and preliminary results available in the literature on its use in IVF suggest its value as adjuvant gonadotropin therapy to reduce the risk of OHSS in PCOS patients.
- Trial name
- FIV-INOPK (NCT02221154)
- Testing
- Inofolic®, Gonadotropins; Folic Acid
- Where
- 4 sites in France
- Volunteers
- 49 people
- Sponsor
- Centre Hospitalier Departemental Vendee
Ovarian Carcinoma
Niraparib Versus Bevacizumab as Maintenance Therapy in Patients With de Novo Ovarian Cancer Without Homologous Recombination Deficiency
Background: High-grade serous epithelial ovarian cancer is a disease with a poor prognosis in the advanced stages (stages III and IV).
- Trial name
- OVNI-B (NCT06827353)
- Testing
- maintenance therapy with bevacizumab, maintenance therapy with niraparib
- Where
- France
- Volunteers
- 300 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Menstrual Problem, Cerebral Palsy
Menstrual Health and Genital Hygiene Status in Cerebral Palsy
There is little information about the menstrual health and genital hygiene behaviors of young women with CP. The most important reason for this is that women with CP did not meet the inclusion criteria and were excluded from the…
- Conditions
- Menstrual Problem, Cerebral Palsy, Women's Health
- Trial name
- NCT04985045
- Testing
- Evaluation
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Özge Çoban
Cancer, Cervical, Recurrence
Retrospective Cervical Cancer Oligo States (Recurrence, Metastasis) Multicentre Outcomes Study
This multi centric international retrospective study aims to register patients with oligo metastatic and oligo recurrent cervical cancer.
- Conditions
- Cancer, Cervical, Recurrence, Metastasis
- Trial name
- Retro-COSMOS (NCT06150222)
- Testing
- Concurrent Chemoradiation, Systemic Chemotherapy other locally directed therapies (like surgery, ablation, etc.)
- Volunteers
- 350 people
- Sponsor
- Erasmus Medical Center
Cervical Cancer, Precancerous Condition
Gene Expression Profiling of Cervical Cancer Progression in Biopsies and Tissue Samples
RATIONALE: Studying samples of tumor tissue from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer.
- Trial name
- SAGE (NCT00629577)
- Testing
- microarray analysis, flow cytometry, biopsy
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- British Columbia Cancer Agency
Metastatic Ovarian Cancer
Prognostic and Predictive Value of HE4 Biomarker in Metastatic Ovarian Cancer
HE4 is a new marker that could improve the detection of ovarian cancer. The HE4 assay may have an advantage over the CA-125 assay in that it is less frequently positive in patients with non malignant disease.
- Trial name
- Meta-Four (NCT01768156)
- Testing
- Experimental arm
- Where
- 2 sites in France
- Volunteers
- 101 people
- Sponsor
- Institut du Cancer de Montpellier - Val d'Aurelle
Endometriosis
MY-ENDO -- Mind Your ENDOmetriosis: a Digital Mindfulness- and Acceptance-based Endometriosis Self-management Program
The purpose of the study is to assess the effect of a digital mindfulness- and acceptance-based psychological intervention on quality of life, work ability, pain experience and physical and mental health in participants…
- Trial name
- NCT06211231
- Testing
- Digitally delivered mindfulness- and acceptance-based psychological intervention
- Where
- 2 sites in Denmark
- Volunteers
- 255 people
- Sponsor
- University of Aarhus
Breast Cancer, Ovarian Cancer
Guilford Genomic Medicine Initiative (GGMI)
Genomic medicine, using genetic information to improve health outcomes, is heralded as the answer to rising medical costs by focusing on prevention and tailored care.
- Conditions
- Breast Cancer, Ovarian Cancer, Colon Cancer, Thrombophilia
- Trial name
- GGMI (NCT01372553)
- Where
- United States
- Volunteers
- 1,184 people, healthy volunteers welcome
- Sponsor
- The Moses H. Cone Memorial Hospital
Endometriosis
Deep Neural Network Stratification for Use Detecting Endometriosis in Women Affected by Chronic Pelvic Pain (EndoCheck)
The goal of this observational study is to determine the clinical validity of a deep neural network algorithm that utilizes protein biomarker detection of Endometriosis - "EndoCheck" - as an "aid in diagnosis" for endometriosis…
- Trial name
- NCT05245695
- Testing
- Observational study, no intervention
- Where
- 10 sites in United States
- Volunteers
- 1,200 people
- Sponsor
- Aspira Women's Health
Ovarian Cancer, Cancer of Ovary
Fenretinide/LXS Oral Powder Plus Ketoconazole in Recurrent Ovarian Cancer
The purpose of this study is to determine the effectiveness of fenretinide (4-HPR/LXS) plus ketoconazole in the treatment of recurrent ovarian cancer or primary peritoneal carcinoma.
- Conditions
- Ovarian Cancer, Cancer of Ovary, Cancer of the Ovary, Ovary Neoplasms
- Trial name
- NCT01535157
- Testing
- Fenretinide/LXS + Ketoconazole
- Where
- 3 sites in United States
- Volunteers
- 12 people
- Sponsor
- South Plains Oncology Consortium
Epithelial Ovarian Carcinoma, Figo Stage IIIC
Intraperitoneal Hyperthermic Chemotherapy in Epithelial Ovarian Carcinoma
Phase II to study results and morbidity of intra peritoneal hyper-thermic chemotherapy as consolidation therapy in patients with FIGO stage IIIC epithelial ovarian carcinoma treated by surgery and a total of 6 cycles of platinum…
- Trial name
- NCT00349505
- Testing
- hyper thermic chemo + surgery
- Where
- France
- Volunteers
- 67 people
- Sponsor
- Gustave Roussy, Cancer Campus, Grand Paris
Fallopian Tube Cancer, Ovarian Cancer
Capecitabine in Treating Patients With Recurrent Ovarian, Fallopian Tube, or Primary Peritoneal Cancer
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. PURPOSE: Phase II trial to study the effectiveness of capecitabine in treating patients who have recurrent…
- Conditions
- Fallopian Tube Cancer, Ovarian Cancer, Primary Peritoneal Cavity Cancer
- Trial name
- NCT00004012
- Testing
- capecitabine
- Where
- United States
- Sponsor
- Memorial Sloan Kettering Cancer Center
Ovarian Diseases, Ankylosing Spondylitis
Ovarian Reserve and Ankylosing Spondylitis
The aim of this study was to determine the status of ovarian reserve in patients with ankylosing spondylitis (AS) using anti-mullerian hormone (AMH) level and antral follicle count (AFC).
- Conditions
- Ovarian Diseases, Ankylosing Spondylitis, Anti-Mullerian Hormone Deficiency
- Trial name
- NCT04209881
- Testing
- ovarian reserve for Ankylosing spondylitis and control groups
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Endometrioma, Thyroid
Comparison of Thyroid Volumes in Patients With and Without Endometrioma
The aim of our study is to evaluate whether there is a statistical difference between thyroid gland volume in patients with pathological diagnosis of endometriosis or endometrioma and in patients who underwent surgery for other…
- Trial name
- NCT05323539
- Testing
- Evaluating Thyroid Volumes by ultrasonography
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Adana City Training and Research Hospital
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