Clinical trials: Genital Endometriosis
Endometriosis, Self Care
Endometriosis Self-Care Behaviors Scale
In this study, it was aimed to develop a reliable and valid scale to measure the self-care behaviors of women with endometriosis.
- Conditions
- Endometriosis, Self Care, Behavior, Nursing Role
- Trial name
- NCT05788978
- Testing
- Scale development
- Where
- Turkey (Türkiye)
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Marmara University
Endometriotic Cyst of Ovary
Letrozole in Preventing Recurrence of Endometrioma Following Laparoscopic Ovarian Cystectomy
Endometriosis is a chronic inflammatory disease that affects approximately 10-15% of women of reproductive age. Symptoms include dysmenorrhoea, chronic pelvic pain, dyspareunia and infertility.
- Trial name
- NCT05487092
- Testing
- Letrozole
- Where
- 5 sites in Hong Kong
- Volunteers
- 194 people
- Sponsor
- The University of Hong Kong
Endometriosis, Uterine Fibrioids
A Study to Evaluate Pregnancy Outcomes in Females Treated With Oral Elagolix Tablets and Capsules
Orilissa is a drug approved for the management of moderate to severe pain associated with endometriosis. Oriahnn is approved for heavy menstrual bleeding due to uterine fibroids.
- Trial name
- NCT04464187
- Where
- United States
- Volunteers
- 173 people
- Sponsor
- AbbVie
Ovarian Endometrioma, Endometriosis
Selective Removal of Endometriotic Lesions Using CUSA Clarity in Ovarian Endometriomas
This study aims to evaluate the feasibility and tissue selectivity of a novel surgical technology, the Cavitron Ultrasonic Surgical Aspirator (CUSA) Clarity, in the management of ovarian endometriomas.
- Trial name
- CUSA-ENDO (NCT07215130)
- Testing
- Cavitron Ultrasonic Surgical Aspirator (CUSA) Clarity
- Where
- Japan
- Volunteers
- 10 people
- Sponsor
- Kanazawa University
Endometriosis
HerResolve™ in Detecting the Presence of Endometriosis Among Symptomatic Women
Endometriosis (EMS) is a common gynecological disease that affects 176 million girls and women globally. EMS affects 5-10% of women and adolescents within the reproductive age range of 15-49 years, and for those facing…
- Trial name
- NCT07006987
- Testing
- A non-invasive blood-based (HerResolve)
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Endometriosis
Microbiome and Immunologic Analysis - Women With Endometriosis
The primary goal of this study is to assess differences in the microbiome between women with and without endometriosis. A second goal of this study is to assess immunologic differences between the eutopic (within the uterus) and…
- Trial name
- NCT04159740
- Testing
- Tissue and blood collection
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Mayo Clinic
Endometriosis, Endometrioma
Mechanisms of Uterine Fluid Absorption During Early Pregnancy ( ELF Study)
The researchers are evaluating mechanisms of uterine fluid absorption during early pregnancy
- Trial name
- NCT06847685
- Where
- 3 sites in United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Endometriosis, Endometriosis-related Pain
Relugolix for Endometriosis Associated Pain
Endometriosis is a chronic, estrogen-dependent condition frequently associated with pelvic pain and reduced quality of life. Relugolix combination therapy (CT), an oral GnRH receptor antagonist-based treatment, has demonstrated…
- Conditions
- Endometriosis, Endometriosis-related Pain, Pelvic Pain Syndrome
- Trial name
- RELAX (NCT07440043)
- Testing
- Patients with a diagnosis of endometriosis receiving treatment with Relugolix CT, according to clinical practice,
- Volunteers
- 33 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Bowel Endometriosis, Endometriosis
Efficacy and Safety of Intra-operative Dual Laparoscopy and Neo-rectoscopy for Bowel Endometriosis: The LUMEN-01 Trial
The goal of this prospective, multicenter, randomized controlled trial is to compare the clinical efficacy and safety of intra-operative dual laparoscopy and neo-rectoscopy (IDLnR) versus conventional laparoscopy (CL) in patients…
- Conditions
- Bowel Endometriosis, Endometriosis, Intestinal Endometriosis
- Trial name
- LUMEN-01 (NCT07523308)
- Testing
- conventional laparoscopy group, intra-operative Dual Laparoscopy and Neo-rectoscopy
- Where
- 3 sites in China
- Volunteers
- 192 people
- Sponsor
- Obstetrics & Gynecology Hospital of Fudan University
Female Infertility, Female Infertility Due to Ovulatory Disorder
Comparative Study on the Efficacy of Ovarian Stimulation Protocols on the Success Rate of ICSI in Female Infertility
The study will describe the effectiveness of ovarian stimulation in correlation with female infertility causes in a Lebanese population: a comparative study using 5 protocols of ovulation induction (treatment with "A"…
- Conditions
- Female Infertility, Female Infertility Due to Ovulatory Disorder, Premature Ovarian Failure, Polycystic Ovary Syndrome
- Trial name
- CS-EOSP-ICSI (NCT04071574)
- Testing
- Human Chorionic Gonadotropin (hCG), Gonadotropins, GNRH-A Triptorelin
- Where
- Lebanon
- Volunteers
- 200 people
- Sponsor
- Lebanese University
Endometriosis
Surgical Eradication of Deep Infiltrating Endometriosis of the Vagina
Multicentric retrospective study about the comparison of two different techniques of vaginal breach suturing after eradication surgery for deep infiltrating endometriosis and the surgical approaches (laparoscopic or vaginal) in…
- Trial name
- ENDO-VAG-r (NCT03744143)
- Testing
- longitudinal suture, transverse suture, Removal of vaginal endometriotic nodule
- Where
- 2 sites in Italy
- Volunteers
- 84 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Endometriosis, Infertility Assisted Reproductive Technology
First Line Surgery or First Line Fertility Treatment Using Assisted Reproductive Technologies in Patients With Advanced Endometriosis
Endometriosis is a chronic disease affecting approximately 10% of women of reproductive age. It is strongly associated with pelvic pain and infertility.
- Trial name
- EndoSOFT (NCT07240363)
- Testing
- Endometriosis surgery
- Where
- 4 sites in Sweden
- Volunteers
- 350 people
- Sponsor
- Karolinska Institutet
Endometriosis
A Study on the Correlation Between Endometriosis and Intra-tissue Microbiota
Endometriosis (EM) is a common gynecological condition, but the pathogenesis of it has not yet been clarified. Here, the investigators wanted to investigate the correlation between endometriosis and the intra-tissue microbiota.
- Trial name
- NCT06266897
- Where
- China
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Zhujiang Hospital
Endometriosis, Endometrial Diseases
Cancer Driving Mutations in Endometriosis Lesions and Development of Progesterone Resistance
This study will test the hypothesis that the molecular changes present in ectopic endometriosis lesions correlate with progesterone-resistant disease (using the criteria defined in this study) and are present in matched eutopic…
- Trial name
- NCT03756480
- Where
- 3 sites in United States
- Volunteers
- 135 people
- Sponsor
- Johns Hopkins University
Endometriosis, Endometriosis-related Pain
Histologic Comparison of Ablative Techniques for Endometriosis
To our knowledge, no other human studies directly compare the effectiveness of the various ablative technologies. We set out to design a study to directly compare ablative energy sources and evaluate their ability to destroy…
- Conditions
- Endometriosis, Endometriosis-related Pain, Endometriosis Pelvic, Endometriosis; Peritoneum
- Trial name
- NCT06414083
- Testing
- Diathermy, CO2 Laser, Argon Beam Coagulator
- Where
- United States
- Volunteers
- 141 people
- Sponsor
- TriHealth Inc.
Endometriosis, Pelvic Pain
Use of TENS Unit in the Management of Endometriosis Pain
The purpose of this study is see if Transcutaneous Electrical Nerve Stimulator (TENS) units help decrease endometriosis flare pain.
- Trial name
- NCT05348005
- Testing
- Ovira Transcutaneous Electrical Nerve Stimulation Unit
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Milton S. Hershey Medical Center
Endometriosis
Research OutSmarts Endometriosis II Study
This product will be used as a diagnostic test to screen for the likelihood of endometriosis in menstruating adults with symptoms suggestive of endometriosis.
- Trial name
- ROSE2 (NCT05601596)
- Testing
- Analysis of menstrual blood to predict endometriosis
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Endometriosis
Remote Electrical Stimulation as a Long-term Intervention for Endometriosis Flare Ups
The goal of this clinical trial is to learn if a wearable brain stimulation device called NettleEndo can reduce chronic pelvic pain and improve wellbeing in women with endometriosis.
- Trial name
- RELIEF (NCT06974773)
- Testing
- NettleEndo
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Samphire Group, Inc.
Infertility, Polycystic Ovary Syndrome
A New Algorithm to Predict Ovarian Age
To collect data of clinical, biochemical and 3D-ultrasonographic parameters of a population of fertile women aged 18-55 in order to design a new algorithm able to predict ovarian age and to evaluate the reliability of a…
- Conditions
- Infertility, Polycystic Ovary Syndrome, Premature Ovarian Failure (POF), Ovarian Cysts
- Trial name
- OvAge (NCT02086318)
- Testing
- OvAge assessment
- Where
- Italy
- Volunteers
- 720 people, healthy volunteers welcome
- Sponsor
- University Magna Graecia
Endometriosis, Mobility Limitation
ENDOMETRIOSIS - MRI
Endometriosis is a frequent pathology with an estimated prevalence of 10% of women of childbearing age. There is no exact correspondence between the symptoms described by the patients and the severity of the lesions, which makes…
- Conditions
- Endometriosis, Mobility Limitation, Magnetic Resonance Imaging, Diagnosis
- Trial name
- ENDO-MRI (NCT05779462)
- Testing
- Dynamic MRI Sequence
- Where
- France
- Volunteers
- 52 people
- Sponsor
- University Hospital, Lille