Clinical trials: Genital Endometriosis
Endometriosis, Fibroids
Evaluating Tibolone Add-back in Patients With Endometriosis and Fibroids
While there are many medical options for managing endometriosis and fibroids, GnRH-agonist (GnRH-a) therapy remains a very common method of treating these complex conditions.
- Trial name
- eTAPE (NCT05568940)
- Testing
- Tibolone 2.5 Mg Oral Tablet
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Endometriosis
Validation and Refinement of Noninvasive Diagnostic Biomarkers for Endometriosis, The ENDOmarker Protocol
This study involves the prospective collection of endometrial biopsy tissue, serum, plasma, whole blood for DNA extraction, and urine from women who will be diagnosed as having (or not having) endometriosis at the time of…
- Trial name
- NCT03161704
- Where
- 5 sites in United States
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Yale University
Endometriosis
Retinal Imaging for Systemic Inflammation in Endometriosis
There is increasing evidence that examining our eyes can tell us a lot of information about our health, and systemic diseases. Our plan is to compare the images taken of the back of eyes of women who have endometriosis with those…
- Trial name
- RISE (NCT07232485)
- Where
- United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Edinburgh
Endometriosis
Safety, Tolerability, Pharmacokinetic and Pharmacodynamic Study of SKI2670
In this Phase I study, the primary objective is to investigate the safety and tolerability of SKI2670 after oral administration in healthy female subjects.
- Trial name
- NCT02202408
- Testing
- SKI2670
- Where
- South Korea
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- SK Chemicals Co., Ltd.
Endometriosis, Cell Free DNA
Cell Free DNA Quantification in Patients With Endometriosis Followed Witd Medical Assistance to Procreation
Endometriosis is a common benign disease in premenopausal women and causes chronic pelvic pain and infertility. This infertility may be due to pelvic adhesions and surgery but also because of poor oocyte quality.
- Trial name
- ENDO-FIV (NCT05815134)
- Testing
- blood sample
- Where
- France
- Volunteers
- 114 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Endometriosis
Treatment by HIFU With Focal One® of Posterior Deep Infiltrating Endometriosis Lesions With Intestinal Involvement.
Deep invasive endometriosis (DIE) includes lesions of the rectosigmoid. Theses lesions are associated with painful symptoms that can alter quality of life.
- Trial name
- NCT03613298
- Testing
- HIFU (Focal One®)
- Where
- France
- Volunteers
- 20 people
- Sponsor
- EDAP TMS S.A.
Endometriosis
Efficacy and Safety of SH T00660AA in Treatment of Endometriosis
The purpose of this study is to demonstrate safety and efficacy of SH T00660AA compared to placebo in the treatment of endometriosis
- Trial name
- NCT00225199
- Testing
- Visanne (BAY86-5258, SH T00660AA)
- Volunteers
- 198 people
- Sponsor
- Bayer
Endometriosis
Effect of Mediterranean Diet and Physical Activity in Patients With Endometriosis
The main aim of this study is to evaluate whether a dietary recommendation based on the Mediterranean diet's principles associated with a regular aerobic physical activity, according to the "7 minutes workout", may improve pain…
- Trial name
- PHAMEDENDO (NCT03994432)
- Testing
- intervention group
- Where
- Italy
- Volunteers
- 140 people
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Endometriosis
Omics Sequencing of Specimen Derived From Patients With Endometriosis
Endometriosis is a type of chronic inflammatory gynecological disease, mainly took place in peritoneal cavity. In order to investigate the possible correlation between microbes and endometriosis, the investigators planed to…
- Trial name
- NCT05086484
- Where
- China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Zhujiang Hospital
Endometriosis
Letrozole vs Danazol for Endometriosis-Related Pain: Randomized Trial
Background: Endometriosis is a chronic gynecological condition defined by the ectopic presence of endometrial glands and stroma outside the uterine cavity, most commonly diagnosed via laparoscopy.
- Trial name
- LET-DAN RCT (NCT07183787)
- Testing
- Letrozole, danazol
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Sidra Salman
Minimally Invasive Surgical Procedures, Abnormal Uterine Bleeding, Unspecified
Cyclobenzaprine for Postoperative Pain in Minimally Invasive Hysterectomy
Typical postoperative pain control after minimally invasive hysterectomy includes ibuprofen, acetaminophen, and a short course of narcotics.
- Conditions
- Minimally Invasive Surgical Procedures, Abnormal Uterine Bleeding, Unspecified, Adenomyosis of Uterus, Fibroid Uterus
- Trial name
- NCT07664956
- Testing
- Cyclobenzaprine
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Christiana Care Health Services
Endometriosis, Chronic Pelvic Pain Syndrome
Multimodal Physiotherapy Based on Tele-rehabilitation in Chronic Pelvic Pain Associated With Endometriosis
Objective: To determine if the tele-rehabilitation program for chronic pelvic pain associated with endometriosis composed of pain education, therapeutic exercise and respiratory control decreases pain according to the Visual…
- Trial name
- NCT06209346
- Testing
- TeleRehab Group, Advices Group
- Where
- Spain
- Volunteers
- 66 people
- Sponsor
- University of Alcala
Menstrual Problem, Quality of Life
Menstrual Wellbeing in Woman Living in Turkey; an Epidemiological Study
Women with endometriosis in our country and around the world face various difficulties during their menstrual periods in reproductive age.
- Trial name
- NCT05442541
- Testing
- not included any interventions(Evaluation of menstrual well-being in women of reproductive age, field survey study)
- Where
- Turkey (Türkiye)
- Volunteers
- 1,829 people, healthy volunteers welcome
- Sponsor
- Dr. Lutfi Kirdar Kartal Training and Research Hospital
Endometriosis
Effects of Intravenous Lidocaine on Endometriosis Pain
We are doing this research study to find out if intravenous (in your vein, "IV") lidocaine can lessen pain from endometriosis. The U.S.
- Trial name
- NCT01968694
- Testing
- IV Lidocaine, IV diphenhydramine
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Brigham and Women's Hospital
Endometriosis, Uterine Fibroids, Male Hormone-sensitive Prostate Cancer, Assisted Reproduction
A Clinical Study Evaluating the Relative Bioavailability of SHR7280 Dry Suspension and Tablets
To assess the relative bioavailability of SHR7280 dry suspension and tablets in healthy subjects. To assess the safety and tolerability of a single dose of SHR7280 dry suspension and tablets.
- Trial name
- NCT05868057
- Testing
- SHR7280 tablets, SHR7280 dry suspension
- Where
- China
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Jiangsu HengRui Medicine Co., Ltd.
Endometriosis
Appendectomy as an Adjunct Procedure in Endometriosis Surgery
This study addresses a common but unresolved clinical decision in endometriosis surgery: whether to perform an adjunct appendectomy.
- Trial name
- AppEND (NCT07823777)
- Testing
- Appendectomy, Standard of Care (SOC)
- Volunteers
- 240 people
- Sponsor
- Mount Sinai Hospital, Canada
Endometriosis
Goserline Acetate VS Dienogest in Endometriosi
clinical trial aims to evaluate efficacy of dienogest (DNG) in comparison to goserline acetate in complete 12 week treatment of pain in women suffer from chronic pelvic pain diagnosed as endometriosis by laparoscopy and…
- Trial name
- NCT05013242
- Testing
- Zoladex, Visanne
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Endometriosis
Guangdong Provincial Endometriosis Clinical Research Cohort
Endometriosis is a chronic condition that may cause pelvic pain, ovarian cysts, infertility, and recurrent symptoms. This prospective observational cohort study will enroll women aged 18 to 45 years with endometriosis and age…
- Trial name
- NCT07749053
- Where
- China
- Volunteers
- 716 people, healthy volunteers welcome
- Sponsor
- Li Li
Endometriosis, Expectations
The Role of Expectations on Complaints and Well-being After Endometriosis Surgery in Women
Endometriosis is a prevalent disease in women of procreative age. Most endometriosis patients are affected in their daily life by complaints such as chronic pelvic pain, dysmenorrhoea, infertility, or pain during sexual…
- Conditions
- Endometriosis, Expectations, Laparoscopy
- Trial name
- ROXWELL (NCT05019612)
- Testing
- Laparoscopy: A minimal invasive surgery
- Where
- Germany
- Volunteers
- 395 people
- Sponsor
- Helmut Schmidt University
Endometriosis
A Study to Learn More About Using Dienogest to Treat Endometriosis in Chinese Participants
Endometriosis is a condition that affects women, usually during their reproductive years. In women with endometriosis, the tissue that lines the uterus starts to grow outside of the uterus.
- Trial name
- VISANNE OS (NCT04495855)
- Testing
- Dienogest (Visanne,BAY86_5258)
- Where
- China
- Volunteers
- 968 people
- Sponsor
- Bayer