Clinical trials: Genital Infection Female
Neoplasm Cervix
Topical Curcumin for HPV Related Cervical Disease
The purpose of this study is to see if curcumin can suppress HPV infection in women with low-grade squamous intraepithelial lesions (LSIL) disease or treated high-grade squamous intraepithelial lesions (HSIL) disease.
- Trial name
- NCT04266275
- Testing
- Curcumin C3 Complex
- Where
- 3 sites in United States
- Volunteers
- 200 people
- Sponsor
- Lisa Flowers
Advanced Solid Tumors, MSI-H/dMMR Tumors
Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of INCB099318 in Participants With Advanced Solid Tumors
The purpose of this study is to evaluate the safety and tolerability, pharmacokinetics, and pharmacodynamics of INCB099318 in select solid tumors.
- Conditions
- Advanced Solid Tumors, MSI-H/dMMR Tumors, Cutaneous Squamous Cell Carcinoma, Urothelial Carcinoma, HCC
- Trial name
- NCT04272034
- Testing
- INCB099318
- Where
- 24 sites in United States, Belgium and 5 more
- Volunteers
- 105 people
- Sponsor
- Incyte Corporation
HIV Infections, HPV-Related Cervical Carcinoma
Self-collected Vaginal and Urine Samples in HIV-positive Women
This study assesses topics as Human Immunodeficiency Virus (HIV), Human Papilloma Virus (HPV), and cancer screening methods. The focus will be on evaluating feasibility of implementing novel cancer screening modalities in a…
- Conditions
- HIV Infections, HPV-Related Cervical Carcinoma, Cervical Cancer, Coinfection, HIV
- Trial name
- NCT05783167
- Testing
- Self-sampling for HPV infection
- Where
- Guinea-Bissau
- Volunteers
- 502 people
- Sponsor
- University of Aarhus
Glutamine; Metabolic Disorder, Physical Activity
Effect of Supplementation With Glutamine and Exercise in Women With HIV/AIDS
This study aimed to investigate the effect of an exercise session with weights associated with glutamine dipeptide (GLD) supplementation on cognitive function of people living with HIV/ AIDS.
- Trial name
- NCT03236532
- Testing
- Glutamine and exercise, Maltodextrin and exercise
- Volunteers
- 14 people
- Sponsor
- State University of Maringá
Chlamydia Trachomatis Infection
Transmission of Genital and Extra-genital Chlamydia Trachomatis Infections in Women
Multicenter prospective cohort study in Chlamydia trachomatis positive women after regular treatment to understand the transmission of anorectal CT infections.
- Trial name
- FemCure (NCT02694497)
- Testing
- Chlamydia care as usual
- Where
- Netherlands
- Volunteers
- 560 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Vaginitis, Bacterial Vaginosis
Real-world Performance and Safety of Cerviron® in the Treatment of Vaginitis
Vaginitis is a broad term that includes a range of gynecological disorders characterized by infection of vaginal mucosa, inflammation of vulva and alteration of the normal vaginal microflora.
- Trial name
- NCT05652959
- Testing
- Cerviron®
- Where
- 10 sites in Romania
- Volunteers
- 111 people
- Sponsor
- Perfect Care Distribution
HIV, Substance Abuse
Implementation Research for Vulnerable Women in South Africa
This study sought to implement the Women's Health CoOp (Cooperative) (WHC) intervention into healthcare, antenatal, and substance treatment clinics in South Africa and translated this evidence-based intervention into real-world…
- Trial name
- NCT02733003
- Testing
- Women's Health CoOp (WHC)
- Where
- 2 sites in United States, South Africa
- Volunteers
- 564 people, healthy volunteers welcome
- Sponsor
- RTI International
Vaginosis, Bacterial
Identification and Impact of Vaginal Flora Anomalies Among Pregnant Woman
This is a prospective multicentric study including six clinical units of Gynecology and Obstetrics (5 public health hospital and one private team), one research team in clinical microbiology and one Center of Clinical…
- Trial name
- NCT00484653
- Testing
- cervical smear
- Where
- 6 sites in France
- Volunteers
- 1,000 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Infections, Papillomavirus, Papillomavirus Vaccines
Human Papillomavirus Vaccine Immunogenicity and Safety Trial in Young Adult Women With GSK Biologicals Novel HPV Vaccine
Infection with human papillomavirus (HPV) has been clearly established as the central cause of cervical cancer. Indeed, certain oncogenic types of HPV can infect the cervix (part of the uterus or womb).
- Trial name
- NCT00359619
- Testing
- CervarixTM, HPV investigational vaccine GSK568893A, different formulations
- Where
- 10 sites in United States, Belgium
- Volunteers
- 383 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Brain and Central Nervous System Tumors, Breast Cancer
Carboxyamidotriazole and Paclitaxel in Treating Patients With Advanced Solid Tumors or Refractory Lymphomas
RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Combining more than one drug may kill more cancer cells.
- Conditions
- Brain and Central Nervous System Tumors, Breast Cancer, Kidney Cancer, Lung Cancer
- Trial name
- NCT00019019
- Testing
- carboxyamidotriazole, paclitaxel
- Where
- 2 sites in United States
- Volunteers
- 70 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
HIV/AIDS
Improve Functional Health Status in Minority Women With HIV
HIV is no longer a death sentence, and with adherence to Rapid High Activity Antiretroviral (HAART) protocol women with HIV can achieve a normal life expectancy.
- Trial name
- NCT04315675
- Testing
- Guided Imagery Intervention, Cognitive Power Intervention, Combined Guided Imagery and Cognitive Power Intervention
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Seton Hall University
Genital Herpes Simplex Type 2
Evaluating New Formulation of Therapeutic HSV-2 Vaccine
This study evaluates the reduction in viral shedding after vaccination with a new formulation of GEN-003 in subjects with genital HSV-2 infection.
- Trial name
- NCT02515175
- Testing
- Matrix-M2, GEN-003
- Where
- 8 sites in United States
- Volunteers
- 131 people
- Sponsor
- Genocea Biosciences, Inc.
Vaginitis Bacterial, Inflammation, Ear
Effect of Lactobacillus Johnsonii or White Pomegranate Extract on the Vaginal Health
The goal of this clinical trial is to explore the effect of Lactobacillus johnsonii and white pomegranate extract on female bacterial status, it aims to answer are: Evaluate Lactobacillus johnsonii TCI250 probiotics or white…
- Trial name
- NCT06069531
- Where
- Taiwan
- Volunteers
- 150 people
- Sponsor
- Chung Shan Medical University
Substance Abuse, Substance Addiction
The Trans-Led Care Study
This study is testing a new mutual-help group called "the TLC program" for transgender adults who use substances or are recently in recovery.
- Conditions
- Substance Abuse, Substance Addiction, Substance Use Disorder (SUD), Substance Use (Drugs, Alcohol)
- Trial name
- TLC (NCT06880705)
- Testing
- The TLC Program
- Where
- United States
- Volunteers
- 124 people
- Sponsor
- Illinois Institute of Technology
HIV Infection, HBV Infection
"Pregnancy and Viral Infections: Impact on Pregnant Women and Their Children. French Prospective Cohort"
The VIROPREG study is a French prospective multicenter cohort study that aims to assess the impact of viral infections and antiviral treatments received during pregnancy on maternal and child health.
- Conditions
- HIV Infection, HBV Infection, HDV Infection, HCV Infection
- Trial name
- VIROPREG (NCT07412977)
- Testing
- Blood sampling, Umbilical cord blood sampling, Survey using a questionnaire
- Where
- France
- Volunteers
- 5,160 people
- Sponsor
- ANRS, Emerging Infectious Diseases
Bacterial Infections, Bacterial Infections and Mycoses
Large Algorithm Setting and Validation Study
In this pilot study, prospectively acquired clinician-collected and participant-collected vaginal swab specimens will be obtained from up to 1000 individuals with signs and symptoms of vaginitis to develop and validate a…
- Conditions
- Bacterial Infections, Bacterial Infections and Mycoses, Infections, Vaginitis
- Trial name
- LAVA (NCT07607470)
- Testing
- Nanopath Vaginitis Assay, BD Max™ Vaginal Panel, Cepheid Xpert® Xpress MVP
- Where
- 2 sites in United States
- Volunteers
- 1,000 people
- Sponsor
- Nanopath, Inc
Human Papillomavirus Infection
Long-term Immune Persistence of a Bivalent HPV Vaccine in Females From Study 311-HPV-1004
This long-term extension study evaluates the persistence of neutralizing antibody responses to a bivalent human papillomavirus vaccine in females who previously participated in study 311-HPV-1004 (NCT02740777).
- Trial name
- NCT07820241
- Testing
- Bivalent Human Papillomavirus Vaccine (Types 16 and 18, Pichia pastoris)
- Where
- 2 sites in China
- Volunteers
- 348 people, healthy volunteers welcome
- Sponsor
- Shanghai Zerun Biotechnology Co.,Ltd
HIV Infections, Pregnancy Related
Pregnancy in Women With HIV Infection
Women living with HIV face multiple challenges regarding pregnancy, encompassing not only their intention to procreate, but also difficulties during the course of pregnancy.
- Trial name
- NCT04350554
- Testing
- Pregnancy
- Volunteers
- 160 people
- Sponsor
- Carlos III Health Institute
Vaginosis, Bacterial
Exploratory Study to Evaluate the Effects of the Probiotics L. Rhamnosus GR-1 and L. Reuteri RC-14
The purpose of this study was to determine whether L. rhamnosus GR-1 and L. reuteri RC-14 delivered via capsules to the vagina of post-menopausal women over a three day course of treatment can restore and maintain a…
- Trial name
- NCT02139839
- Testing
- Lactobacillus capsules
- Where
- Canada
- Volunteers
- 14 people
- Sponsor
- Kimberly-Clark Corporation
Female Genital Warts
The Psychosocial and Economic Burden of Genital Warts
Considering the importance of HPV(human papilomavirus) and related diseases in Brazil, and the lack of studies about both the economic and the psychosocial burden of these diseases, BEMFAM, a Brazilian non-governmental…
- Trial name
- GWburden (NCT01520194)
- Testing
- women attending reproductive health clinics, medical records
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- BEMFAM-Bem Estar Familiar
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