Clinical trials: Genital Infection Female
HPV
Self-Collected Swabs for Primary Human Papilloma Virus (HPV) Screening
In this study, the investigators will assess whether implementing a self-swab protocol for primary Human Papilloma Virus (HPV) testing is an effective method to increase cervical cancer screening in a sample of unscreened women…
- Trial name
- NCT05989464
- Testing
- Self-swab for genital HPV
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- University of Hawaii
Contraceptive Behavior, Sexually Transmitted Diseases
The Young Woman's Reach Project: Trial of an Intervention to Impact Contraceptive Behavior, Unintended Pregnancy, and Sexually Transmitted Infections (STIs) Among Adolescent Females
The New Generation Health Center/University of California, San Francisco (UCSF) will implement an intervention to impact contraceptive behavior and reduce unintended pregnancy and sexually transmitted infections (STIs) among…
- Trial name
- REACH (NCT00230880)
- Testing
- follow-up phone counseling
- Where
- United States
- Volunteers
- 800 people
- Sponsor
- University of California, San Francisco
Bacterial Vaginosis, Vaginal Dysbiosis
AUTOP 2: Screen-and-treat Strategy for Vaginal Flora Abnormalities by Molecular Biology in Pregnant Women at High Risk of Preterm Birth
Preterm birth is a major cause of mortality and long-term disability. Bacterial vaginosis (BV) is a frequent form of dysbiosis that is often asymptomatic and increases the risk of preterm birth.
- Conditions
- Bacterial Vaginosis, Vaginal Dysbiosis, Premature Delivery
- Trial name
- AUTOP 2 (NCT06349122)
- Testing
- Vaginal flora abnormalities screening and quantification using molecular biology technique, Azithromycin, Ceftriaxone
- Volunteers
- 1,794 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Atherosclerosis, Chlamydia Infections
Effects of Hormone Therapy on the Immune Systems of Postmenopausal Women With Chronic Infections
Hardening of the arteries (atherosclerosis) and heart disease are much more common in men than in women. However, as women grow older, especially after menopause the incidence of atherosclerosis and heart disease increases.
- Conditions
- Atherosclerosis, Chlamydia Infections, Cytomegalovirus Infections, Pneumonia, Bacterial
- Trial name
- NCT00001890
- Testing
- Estrogen therapy
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Vaginal Infection
Multi-Center Study of New Medications to Treat Vaginal Infections
The purpose of this study is to evaluate the safety and efficacy of terconazole gel in the treatment of vaginal infections
- Trial name
- SMART GIVES (NCT02308046)
- Testing
- Terconazole
- Where
- 41 sites in United States
- Volunteers
- 212 people
- Sponsor
- Curatek Pharmaceuticals, LLC
Vaginal Infection, Breastmilk Collection
Evaluation of Breastmilk Microbiota as a Function for Immunity
The aim of this study is to evaluate the difference of breast milk microbiota between mothers with and without vaginal infections during pregnancy.
- Trial name
- NCT05005286
- Testing
- Past history of vaginal Infections
- Where
- Malaysia
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Universiti Sains Malaysia
Vaginal Infection
Epidemiology of Abnormal Vaginal Discharge During Pregnancy
Vaginitis among women of childbearing age is well acknowledged as a public health concern due to its high occurrence. Vulvovaginitis is a disorder of the vulva and/or vagina caused by infection, inflammation, or changes in the…
- Trial name
- NCT04719754
- Testing
- Vaginal swab
- Where
- Egypt
- Volunteers
- 164 people
- Sponsor
- Assiut University
HIV Infections, Depression
Integrating HIV and Depression Self-Care to Improve Adherence in Perinatal Women
Depression is a common perinatal complication that can have a profound, adverse effect on maternal and child health outcomes. The proposed study will directly address this important, but understudied area by evaluating the…
- Trial name
- NCT03016546
- Testing
- BEST-maCARE, Attention Control Condition
- Where
- India
- Volunteers
- 40 people
- Sponsor
- Yale University
Urinary Tract Infection, Prostatitis
FOsfomycin for Male Urinary Tract Infection
Male urinary tract infections (MUTI) are often less recognised compared to those in women. French clinical guidelines practices recommend the use of antibiotics called fluoroquinolones, which are highly effective in treating…
- Conditions
- Urinary Tract Infection, Prostatitis, Cystitis
- Trial name
- FOMUTI (NCT06822751)
- Testing
- Fosfomycun-trometamol
- Where
- France
- Volunteers
- 138 people
- Sponsor
- University Hospital, Rouen
Cancer
Intravenous VEGF Trap in Treating Patients With Relapsed or Refractory Advanced Solid Tumors or Non-Hodgkin's Lymphoma
RATIONALE: VEGF Trap may stop the growth of solid tumors or non-Hodgkin's lymphoma by stopping blood flow to the tumor. PURPOSE: This phase I trial is studying the side effects and best dose of intravenous VEGF Trap in treating…
- Trial name
- NCT00083213
- Testing
- ziv-aflibercept
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Regeneron Pharmaceuticals
Cervical Cancer, Human Papilloma Virus Infection
e- Ab Sensor-based Real-time Detection of Oncogenic Human Papilloma Viruses
To develop a real-time diagnostic technique with e- Ab sensor for high risk human papilloma viruses(high risk HPV) detection, the investigators conduct a prospective clinical study.
- Trial name
- NCT01387997
- Testing
- Electrosensing antibody probing system (e- Ab sensor)
- Where
- Taiwan
- Volunteers
- 72 people
- Sponsor
- National Taiwan University Hospital
Cervical Intraepithelial Neoplasia (CIN), Cervical Cancer
Correlation Between Selenium Levels in Human Tissues and HPV-related Cervical Lesions and Outcomes
This study investigates the relationship between selenium levels in human tissues and the persistence of HPV (human papillomavirus) infection, particularly focusing on cervical-related lesions.
- Conditions
- Cervical Intraepithelial Neoplasia (CIN), Cervical Cancer, Persistent HPV Infection
- Trial name
- SeHPV (NCT06665841)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Human Immunodeficiency Virus
Special Investigation of Kaletra in Pregnant Women
This non-interventional, post-marketing observational study was conducted to obtain safety data from the use of lopinavir/ritonavir (Kaletra), in clinical practice, in pregnant women and their children in Japan.
- Trial name
- NCT01076985
- Testing
- Lopinavir/ritonavir (Kaletra)
- Where
- 5 sites in Japan
- Volunteers
- 24 people
- Sponsor
- Abbott
Cervical Cancer Screening, HIV Infections
Anal HPV Infection and Abnormal Cytology in HIV-infected Women
The population of HIV infected women seen at Boston Medical Center may have a higher frequency of anal cytologic and histologic abnormalities than what is reported for the non-HIV infected population.
- Trial name
- NCT00933140
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Boston Medical Center
Vaginal Cuff Dehiscence, Vaginal Hematoma
Laparoscopic Versus Transvaginal Cuff Closure
It is still debatable whether that the transvaginal approach to vault closure or laparoscopic suturing are associated with lower risks of vaginal cuff complications .
- Conditions
- Vaginal Cuff Dehiscence, Vaginal Hematoma, Vaginal Infection
- Trial name
- NCT03898726
- Testing
- laparoscopical l cuff closure
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- El-Galaa Military Medical Complex
Vulvovaginal Candidiasis
A Randomized Study Evaluating the Therapeutic Equivalence of Two Butoconazole Nitrate Vaginal Cream, 2% Formulations
This was a study that compared the efficacy and safety of a generic butoconazole nitrate vaginal cream, 2% to Gynazole-1 (butoconazole nitrate) Vaginal Cream, 2% in the treatment of vulvovaginal candidiasis caused by Candida…
- Trial name
- NCT01039584
- Testing
- Butoconazole Nitrate Vaginal Cream, Gynazole 1 vaginal cream
- Where
- United States
- Volunteers
- 611 people, healthy volunteers welcome
- Sponsor
- Padagis LLC
Chronic Kidney Diseases, Diabetes Mellitus
Prevalence of Chronic Kidney Disease (CKD) and Risk Factors in Sub-Saharan Africa
Prospective cross-sectional study at the outpatient clinic (OPC) of the Bagamoyo District Hospital (BDH) in Tanzania. Assessment of basic epidemiological data (Point prevalence and risk factors) on CKD with simple clinical…
- Conditions
- Chronic Kidney Diseases, Diabetes Mellitus, Hypertension, Tuberculosis
- Trial name
- RenalOne (NCT03458338)
- Testing
- estimated glomerular filtration rate and albuminuria
- Where
- Switzerland
- Volunteers
- 1,006 people
- Sponsor
- University Hospital, Basel, Switzerland
HIV Infections
Evaluating the Safety of and Adherence to a Vaginal Matrix Ring Containing Dapivirine and Oral Emtricitabine/Tenofovir Disoproxil Fumarate in an Adolescent and Young Adult Female Population
The purpose of this study is to evaluate the safety of and adherence to a vaginal matrix ring (VR) containing dapivirine and oral emtricitabine/tenofovir disoproxil fumarate (FTC/TDF) in adolescent and young adult females.
- Trial name
- NCT03593655
- Testing
- Dapivirine vaginal ring, FTC/TDF
- Where
- 4 sites in South Africa, Uganda and 1 more
- Volunteers
- 247 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Cervical Cancer, Condylomata Acuminata
Broad Spectrum HPV Vaccine Tolerability, Immunogenicity, and Efficacy Study (V502-003)
This study is to evaluate an investigational vaccine with the following objectives: (1) To demonstrate prevention of cervical, vulvar, and vaginal cancers and related precancers, external genital lesions, and persistent infection…
- Trial name
- NCT00365443
- Testing
- V502
- Volunteers
- healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
HPV Infection, Virus Integration
Prognostic Study of HPV Virus Integration in Women With HSIL
Human papillomavirus (HPV) is currently one of the most common sexually transmitted infections, according to its carcinogenicity is divided into high-risk genotypes and low-risk genotypes, research has confirmed that carcinogenic…
- Conditions
- HPV Infection, Virus Integration, HSIL, High Grade Squamous Intraepithelial Lesions
- Trial name
- NCT05745597
- Testing
- Follow up
- Where
- 13 sites in China
- Volunteers
- 1,000 people
- Sponsor
- Fujian Maternity and Child Health Hospital
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