Clinical trials: Genital Neoplasm
Poly Cystic Ovary Syndrome
The Effect Of Polycystic Ovarian Syndrome Treatment On Ocular Surface.
This is a Descriptive prospective cohort study conducted at the Ophthalmology Department in Kasr-Alaini Hospital. A total of 90 subjects, 30 control females with no relevant medical, gynecological or ophthalmic history, and 60…
- Trial name
- NCT07419776
- Testing
- dry eye diagnostic system of Mediworks, Optical coherence tomography angiography, Contraceptives, Oral, Combined
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Cairo University
Prostate Cancer
Mild Cognitive Impairment in Men Following Androgen Deprivation
MCI with ageing is thought in part to be related to reduced serum sex hormones which is well-recognised, especially in females, but poorly understood.
- Trial name
- NCT01691976
- Testing
- Oestrogen Patches, LHRHa
- Where
- United Kingdom
- Volunteers
- healthy volunteers welcome
- Sponsor
- Imperial College London
Intraepithelial Neoplasia
Genotypification and Predisposing Factors in Human Papilloma Virus Infection
Objective: Determine the genotypes and risk factors associated with human papilloma virus infection in Mexican women. Methods: It was a cross-sectional study of women attended at the Materno-Perinatal Hospital "Mónica Pretelini"…
- Trial name
- HPV (NCT01924117)
- Testing
- Linear Array HPV Genotyping assay
- Volunteers
- 129 people, healthy volunteers welcome
- Sponsor
- Materno-Perinatal Hospital of the State of Mexico
Papillomavirus Infections, Coronavirus Disease (COVID-19)
Safety and Immunogenicity of 9-valent Human Papillomavirus (9vHPV) Vaccine Coadministered With Messenger Ribonucleic Acid (mRNA)-1273 Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) (COVID-19) Vaccine (V503-076)
The purpose of this study to evaluate the safety and immunogenicity of a 2-dose regimen of 9vHPV vaccine, where the first dose is administered concomitantly with a first dose of a 2-dose regimen of mRNA-1273 vaccine versus…
- Trial name
- NCT05119855
- Testing
- 9vHPV Vaccine, mRNA-1273 Vaccine
- Where
- 38 sites in United States
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Cervical Cancer, Stigma
Effectiveness of a Cervical Cancer Stigma Reduction Intervention Program on Cancer Stigma Score and Cervical Cancer Screening Uptake in Nepal
It is an interventional study to assess the effectiveness of the cervical cancer stigma reduction intervention on cancer stigma score and cervical cancer screening uptake in Nepal
- Conditions
- Cervical Cancer, Stigma, Screening
- Trial name
- NCT05489978
- Testing
- "Cervical Cancer Stigma Reduction Intervention"
- Where
- Nepal
- Volunteers
- 310 people, healthy volunteers welcome
- Sponsor
- Kathmandu University School of Medical Sciences
Cervical Cancer
Effects of Decision Aids on the Participation of South Asian Women in Cervical Cancer Screening
Objectives: To examine the effects of linguistically appropriate decision aids on decisional conflicts, risk perception, clarity of values, screening decisions and screening uptake among South Asian women in Hong Kong Design and…
- Trial name
- NCT06069648
- Testing
- printed screening decision aid, a leaftlet, mobile screening decision aid
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Cervical Cancer
Mobile High-Resolution Microendoscopy (mHRME) for the Detection of Cervical Dysplasia in El Salvador
Evaluate the performance of the mHRME in a study of 3,000 women in San Salvador to assess whether mHRME imaging improves specificity of screening by VIA or HPV DNA without reducing sensitivity for cervical precancer and cancer.
- Trial name
- NCT04472455
- Testing
- HRME
- Volunteers
- 1,827 people, healthy volunteers welcome
- Sponsor
- William Marsh Rice University
Cervical Cancer
Vietnamese Women's Health Project III
The purpose of this protocol is to understand the extent of symptom perception and preventive care-seeking among Vietnamese American women and their impact on cervical cancer screening from the perspectives and experiences of key…
- Trial name
- NCT01704235
- Testing
- Demographic Form and Semi-Structured Interview Guide
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- OHSU Knight Cancer Institute
Prostate Cancer
Positron Emission Tomography / Magnetic Resonance Imaging (PET/MRI) Guided Biopsy in Men With Elevated PSA
In 22% of patients with elevated Prostate-specific antigen (PSA) MRI guided biopsy will not detect significant prostate cancer (PCA) (defined as either: Gleason score (GS) ≥ 3+4 or tertiary pattern 5, or final stage ≥ pT3a and/or…
- Trial name
- NCT03187990
- Testing
- [68Ga]PSMA-11, [18F]PSMA-1007
- Where
- Switzerland
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Irene Burger
Ovarian Cancer
Chemotherapy-Related Toxicities In Ovarian Cancer Patients
Primary Objectives: 1. To assess the preferences of women with ovarian cancer, their clinical caregivers, familial caregivers, and a control group for toxicities associated with chemotherapy.
- Trial name
- NCT00508378
- Testing
- Interview, Questionnaire
- Where
- United States
- Volunteers
- 288 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Polycystic Ovary Syndrome, Gestational Diabetes Mellitus
Screening for GDM in Women With PCOS and Controls
Women with polycystic ovary syndrome (PCOS) are often insulin resistant. During pregnancy, insulin sensitivity decreases. The investigators examine glucose metabolism during oral glucose tolerance test and the incidense of…
- Trial name
- NCT02183558
- Testing
- OGTT by randomization, OGTT by indication
- Where
- Denmark
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Cervical Cancer
Using CHWs and HPV Home Tests to Increase Cervical Cancer Screening in Minority Populations
Caribbean immigrants (both Hispanics and Blacks from Haiti) are less likely to be screened for cervical cancer than the general population.
- Trial name
- SUCCESS (NCT02121548)
- Testing
- CHW Outreach and HPV Self-sampling, CHW Outreach
- Where
- United States
- Volunteers
- 601 people, healthy volunteers welcome
- Sponsor
- University of Miami
Prostate Cancer
Decision Making in Unaffected First-Degree Relatives of Prostate Cancer Patients
There are two parts to this study: (1) an information gathering phase leading to development of a new decision aid (phase 1); and (2) a study to test the newly developed decision aid (phase 2).
- Trial name
- NCT00815750
- Testing
- Information Gathering, Decision Aid
- Where
- 2 sites in United States
- Volunteers
- 147 people, healthy volunteers welcome
- Sponsor
- H. Lee Moffitt Cancer Center and Research Institute
Fallopian Tube Cancer, Peritoneal Cavity Cancer
A Study of Carboplatin, PLD and Everolimus in Certain Gynecologic Cancer
RATIONALE: Drugs used in chemotherapy, such as carboplatin and pegylated liposomal doxorubicin hydrochloride (PLD) work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from…
- Conditions
- Fallopian Tube Cancer, Peritoneal Cavity Cancer, Recurrent Ovarian Epithelial Cancer
- Trial name
- NCT01281514
- Testing
- everolimus, carboplatin, pegylated liposomal doxorubicin hydrochloride
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Fox Chase Cancer Center
Polycystic Ovary Syndrome
Intrauterine Environment in Polycystic Ovary Syndrome (PCOS) Probands
Polycystic ovary syndrome (PCOS) is among the most common endocrine disorders in premenopausal women, affecting 7-10% of this population.
- Trial name
- NCT00364949
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Polycystic Ovary Syndrome
Comparison of Docosahexaenoic (DHA) Values in Patients With Polycystic Ovary Syndrome (PCOS)
Although PCOS has been known for many years, its etiology and treatment are not clearly known. The prevalence of PCOS varies between populations.
- Trial name
- NCT05597111
- Testing
- DHA levels of blood and cervical mucus
- Where
- Turkey (Türkiye)
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- Recep Tayyip Erdogan University Training and Research Hospital
Endometrial Carcinoma
Combination Chemotherapy of Paclitaxel and Carboplatin With or Without Anthracycline as Aneo Adjuvant Treatment in Advanced Endometrial Carcinoma
Endometrial cancer, the most common gynecologic cancer worldwide, is steadily increasing in developed countries.The early-stage forms of endometrial cancer are usually highly curable by surgical treatment alone, whereas advanced…
- Trial name
- NCT06102252
- Testing
- Paclitaxel/epirubcin/carboplatin, Paclitaxel/carboplatin
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sohag University
Cancer-related Problem/Condition, Sexuality
The Find Your PATHS (Pragmatic Assessment of a Tool to Help Survivors) to Sexual Health and Parenthood Study
Concerns with sexual health and fertility are common among cancer patients, survivors and their partners. Literature reviews suggest that over 60% of survivors have reproductive health problems yet fewer than 20% get professional…
- Conditions
- Cancer-related Problem/Condition, Sexuality, Fertility
- Trial name
- PATHS (NCT03345264)
- Testing
- Online, interactive self-help program
- Where
- United States
- Volunteers
- 361 people, healthy volunteers welcome
- Sponsor
- American Cancer Society, Inc.
Polycystic Ovary Syndrome
Evaluation of Serum Prostatic Specific Antigen (PSA) After Cyproterone Compound Treatment Compared With Oral Contraceptives Pill in Hirsute Polycystic Ovary Syndrome Patients
The purpose of this study is to evaluate the effect of oral contraceptive on the serum free prostatic specific antigen (PSA)in women with polycystic ovary syndrome(PCOD)compared with cyproterone compound.
- Trial name
- PSA (NCT00955058)
- Testing
- OCP
- Where
- Iran
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Shahid Beheshti University
Polycystic Ovary Syndrome
PCOSMIC Trial - PolyCystic Ovary Syndrome, Metformin for Infertility With Clomiphene
1. Metformin increases the pregnancy rate when added to the standard treatment of anovulatory polycystic ovary syndrome (PCOS). 2.
- Trial name
- PCOSMIC (NCT00795808)
- Testing
- Metformin, Metformin + Clomiphene, Clomiphene
- Where
- New Zealand
- Volunteers
- 171 people, healthy volunteers welcome
- Sponsor
- University of Auckland, New Zealand
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