Clinical trials: Genital Neoplasms, Male
Breast Cancer, Prostate Cancer
A Study of Meaning-Centered Therapy for Mexican Adults With Advanced Cancer
The purpose of this study is to find out if Meaning-Centered Psychotherapy for Latinos (MCP-L) helps reduce anxiety and depression and improves quality of life compared to cognitive behavioral therapy (CBT).
- Conditions
- Breast Cancer, Prostate Cancer, Colorectal Cancer, Thyroid Cancer
- Trial name
- NCT07225309
- Testing
- Meaning-Centered Psychotherapy for Latinos /MCP-L
- Where
- 2 sites in United States, Mexico
- Volunteers
- 300 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Prostatic Cancer
Autologous Dendritic Cell Therapy for Hormone-Refractory Metastatic Prostate Cancer
This is an open label, Phase I/IIa trial of immunotherapy with CreaVax-PC as treatment in men with hormone-Refractory Metastatic Prostate Cancer.
- Trial name
- NCT01171729
- Testing
- Autologous dendritic cell
- Where
- 2 sites in South Korea
- Volunteers
- 12 people
- Sponsor
- Samsung Medical Center
Prostate Cancer
Flu/TBI in Treating Patients Not Responding to Previous Hormone Therapy
RATIONALE: Giving low doses of chemotherapy, such as fludarabine, and radiation therapy before a donor stem cell transplant helps stop the growth of cancer cells.
- Trial name
- NCT00242931
- Testing
- Nonmyeloablative stem cell conditioning regimen
- Sponsor
- OHSU Knight Cancer Institute
Prostate Cancer
Vaccine Therapy Plus QS21 in Treating Patients With Progressive Prostate Cancer
RATIONALE: Vaccines may make the body build an immune response to kill tumor cells. PURPOSE: Phase I trial to study the effectiveness of vaccine therapy given with QS21 in treating patients who have progressive prostate cancer.
- Trial name
- NCT00003819
- Testing
- QS21, TF(c)-KLH conjugate vaccine, Thomsen-Friedenreich antigen
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Prostate Cancer
Innovative Planning and Guidance System for Prostate Focal Brachytherapy
A key feature of low-dose brachytherapy is that irradiation affects only a local area around the inserted radiation sources. The exposure of healthy tissues around these sources is then reduced.
- Trial name
- FOCUS (NCT03160365)
- Testing
- ACQUISITION OF IMAGES
- Where
- France
- Volunteers
- 34 people
- Sponsor
- University Hospital, Brest
Bladder Cancer, Prostate Cancer
Occupational Situation and Return to Work of Urological Patients
This study will examine the work status of all adult patients admitted over a 6-month period to the University Hospital in Kraków, Poland, for treatment of urological diseases.
- Conditions
- Bladder Cancer, Prostate Cancer, Renal Cancer, Urinary Stones
- Trial name
- OCCURORTW (NCT07088536)
- Testing
- Occupational Status Survey and Telephone Follow-up and Quality-of-Life Assessment in a subset of patients
- Where
- Poland
- Volunteers
- 2,000 people
- Sponsor
- Jagiellonian University
Obesity, Colorectal Cancer
Prevention of Obesity-related Cancers: Setting up of a Multi-Cancer Education and Prevention Program in Hong Kong
Obesity could increase the risk of many chronic diseases, including hypertension, cardiovascular diseases, high lipid level, diabetes, stroke, endometrial cancer and certain types of cancer which could benefit by secondary…
- Conditions
- Obesity, Colorectal Cancer, Prostate Cancer, Breast Cancer
- Trial name
- NCT04034953
- Testing
- Faecal Immunochemical Test, Prostate-Specific Antigen Test, Mammogram
- Where
- Hong Kong
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Testicular Cancer, Leukemia
Early Life Exposures in Agriculture
Background: The Agricultural Health Study (AHS) studied farmers and their spouses in North Carolina and Iowa. It also included people who worked with pesticides in Iowa.
- Conditions
- Testicular Cancer, Leukemia, Lymphoma, Brain Cancer
- Trial name
- NCT02743481
- Where
- United States
- Volunteers
- 60,000 people
- Sponsor
- National Cancer Institute (NCI)
Prostate Cancer
Efficacy, Safety, and Pharmacokinetics of FP-014, 11.25 mg in Patients With Advanced Prostate Cancer
This is a study in male patients with advanced prostate cancer who are eligible for androgen ablation therapy. The study duration will be up to 26 weeks. Eligibility will be assessed during a screening period of up to 28 days.
- Trial name
- KATANA E3M (NCT06795178)
- Testing
- FP-014
- Sponsor
- Foresee Pharmaceuticals Co., Ltd.
Clear Cell Renal Cell Carcinoma, Locally Advanced Pancreatic Cancer
Ceralasertib (AZD6738) Alone and in Combination With Olaparib or Durvalumab in Patients With Solid Tumors
This phase II trial studies how well ceralasertib, am Ataxia telangiectasia and Rad3-related (ATR) kinase inhibitor, works alone or in combination with olaparib or durvalumab in treating participants with renal cell carcinoma…
- Conditions
- Clear Cell Renal Cell Carcinoma, Locally Advanced Pancreatic Cancer, Locally Advanced Malignant Solid Neoplasm, Metastatic Malignant Solid Neoplasm
- Trial name
- NCT03682289
- Testing
- Ceralasertib, Olaparib, Durvalumab
- Where
- 3 sites in United States
- Volunteers
- 83 people
- Sponsor
- Rahul Aggarwal
Prostatic Neoplasms
Study of Trovax® Plus Docetaxel Versus Docetaxel Alone in Patients With Progressive Hormone Refractory Prostate Cancer
The purpose of this study is to evaluate the role of combination therapy with Trovax plus Docetaxel or Docetaxel alone in patients with prostate cancer with a rising prostate specific antigen (PSA).
- Trial name
- NCT00521274
- Testing
- MVA 5T4, Docetaxel
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- The Methodist Hospital Research Institute
Prostate Cancer
Enzalutamide and Hormone Therapy Before, During, and After Radiation for High Risk Localized Prostate Cancer
The study is being done to find out whether combining two FDA approved drugs along with radiation therapy for the treatment of high risk localized prostate cancer is safe and well tolerated.
- Trial name
- NCT02064582
- Testing
- Enzalutamide, Leuprolide acetate, radiation
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- University of Texas Southwestern Medical Center
Brain and Central Nervous System Tumors, Childhood Germ Cell Tumor
Amifostine to Protect From Side Effects of PSCT in Treating Patients With Solid Tumors
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining chemotherapy with peripheral stem cell transplantation may allow the doctor to give higher doses of…
- Conditions
- Brain and Central Nervous System Tumors, Childhood Germ Cell Tumor, Chordoma, Kidney Cancer
- Trial name
- NCT00003926
- Testing
- amifostine trihydrate, busulfan, filgrastim
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Masonic Cancer Center, University of Minnesota
Detection and Characterization of Prostate Cancer Based on Artificial Intelligence
Automatic Detection in MRI of Prostate Cancer: DAICAP
Prostate cancer is the most common cancer in France and the 3rd most common cancer death in humans. The introduction of pre-biopsy MRI has considerably improved the quality of prostate cancer (PCa) diagnosis by increasing the…
- Trial name
- DAICAP (NCT05513820)
- Where
- France
- Volunteers
- 1,250 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Prostate Cancer, Adenocarcinoma of the Prostate
Prospective Prostate Cancer and Patient-reported Outcomes Registry
This study aims to evaluate the use of a digital solution, integrated into the electronic health record, for prospective and structured reporting of clinical and patient-reported outcomes for patients diagnosed with localized or…
- Conditions
- Prostate Cancer, Adenocarcinoma of the Prostate, Locally Advanced Prostate Carcinoma, Locally Advanced Prostate Adenocarcinoma
- Trial name
- Prosquare (NCT04694924)
- Testing
- standard of care
- Where
- 4 sites in Belgium
- Volunteers
- 5,000 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Prostate Cancer
SBRT vs. Conventional Fractionation With HDR Boost for Prostate Cancer
Random assignment between SBRT and conventionally fractionated boost following HDR brachytherapy for prostate cancer.
- Trial name
- SHARP (NCT04861415)
- Testing
- Sterotactic Body Radiotherapy, Conventionally Fractionated Radiation
- Where
- Canada
- Volunteers
- 55 people
- Sponsor
- Dr. Gerard Morton
Prostate Cancer
Pedometer and Exercise Study in Prostate Cancer Patients With Hormonal Therapy
A randomized clinical trial evaluating the use of a pedometer and brief exercise coaching in prostate cancer patients treated with androgen deprivation therapy.
- Trial name
- NCT00868868
- Where
- Canada
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Groupe de recherche en Urologie de la Mauricie
PCOS (Polycystic Ovary Syndrome) of Bilateral Ovaries
Effect of Hyperandrogenism on IVF Outcomes in PCOS Patients
Ovulatory dysfunction affects 18 to 25% of infertile women, the most common identifiable condition is polycystic ovarian syndrome (PCOS).
- Trial name
- HIP (NCT05555680)
- Testing
- Ferriman-Gallwey Score
- Where
- Canada
- Volunteers
- 32 people
- Sponsor
- Clinique Ovo
Prostate Cancer (Adenocarcinoma), Low and Intermediate Risk Prostate Cancer
Micro-ultrasound-Guided Focal Laser Ablation for Intermediate-Risk Prostate Cancer: Safety & Effectiveness
This clinical research study is intended to show that Micro-Ultrasound Guided Focal Laser Ablation (MicroUSgFLA) is a safe procedure that can significantly postpone or eliminate the need for patients with intermediate-Risk…
- Trial name
- MicroUSgFLA (NCT07339943)
- Testing
- 6 month, prospective, interventional single-arm safety and effectiveness study, The TRANBERG|CLS Thermal therapy
- Where
- Canada
- Volunteers
- 7 people
- Sponsor
- University Health Network, Toronto
Prostate Cancer
PD-L1-expressing Regulatory T Cells in Localized Prostate Cancer Patients Undergoing Iodine-125 Permanent Brachytherapy
Immunotherapy is currently revolutionizing the field in oncology. However, prostate cancer is poorly responsive to immune checkpoint inhibition.
- Trial name
- NCT04369508
- Testing
- permanent brachytherapy
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Xuanwu Hospital, Beijing
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