Clinical trials: Genital Prolapse
Genital Prolapse
Observing Pelvic Organ Prolapse Symptoms And Treatment Outcomes
To prospectively observe the outcomes of surgical prolapse treatment in terms of urinary, bowel, and sexual function, quality of life, patient satisfaction, cost, and achieving patient determined treatment goals.
- Trial name
- NCT00784602
- Where
- United States
- Volunteers
- 301 people
- Sponsor
- Melissa Fischer, MD
Vaginal Prolapse
Clinical Assessment of the Total Vaginal Mesh Technique for Treatment of Genital Prolapse
Pelvic floor prolapse is a general term used to describe various clinical conditions that are associated with pelvic floor (muscles that support the vagina) relaxation in female patients.Pelvic floor prolapse is thought to result…
- Trial name
- NCT00196495
- Testing
- Polypropylene Mesh
- Volunteers
- 90 people
- Sponsor
- Ethicon, Inc.
Vaginal Prolapse
0050-19-RMB CTIL - VNOTES Compared to VH for Vaginal Apex Prolapse
VNOTES (Transvaginal natural orifice transluminal endoscopic surgery) is a relatively new surgery for Hysterectomy and Uterosacral ligament suspension to treat Vaginal prolapse.
- Trial name
- NCT04078802
- Testing
- VNOTES/VH
- Volunteers
- 60 people
- Sponsor
- Rambam Health Care Campus
Uterine Prolapse
Laparoscopic Surgery in Elderly Patients
The primary purpose is to evaluate the quality of post-operative recovery and post-operative pain in elderly patients (more than 75 years) who undergo laparoscopic surgery for uterine prolapse.
- Trial name
- NCT03095716
- Testing
- laparoscopic surgery
- Where
- France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Clermont-Ferrand
Pelvic Organ Prolapse
Effects of Pelvic Floor Muscle Training With & Without Hypopressive Exercises
Pelvic Organ Prolapse (POP) is a prevalent condition affecting women's quality of life due to the descent of pelvic organs caused by weak pelvic floor muscles (PFMs).
- Trial name
- NCT07440875
- Testing
- hypopressive excercises, pelvic training excercises
- Where
- Pakistan
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Sacral Colpopexy, Pelvic Organ Prolapse
Male Sexual Experience and Its Impact on Quality of Life Before and After Their Sexual Partners Undergo Polypropylene Mesh Augmented Pelvic Floor Reconstruction
The correction of the pelvic organ protrusion is aimed at restoring the pelvic floor functional status and ultimately improving the patient's quality of life.
- Trial name
- SEXQ (NCT01320631)
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Atlantic Health System
Pelvic Floor Disorders, Obstetric Trauma
Correlation Pelvic Floor Function and Ultrasound Findings One Year After Childbirth
This is a single-center prospective cohort study sponsored by the University Hospitals Leuven (UZ). Women will undergo a pelvic floor ultrasound and will be asked to fill out a questionnaire at the time of their admission into…
- Conditions
- Pelvic Floor Disorders, Obstetric Trauma, Urinary Incontinence, Anal Incontinence
- Trial name
- DeliverUU (NCT05530681)
- Testing
- Questionnaire, Pelvic floor ultrasound
- Where
- Belgium
- Volunteers
- 320 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Uterine Prolapse, Urinary Incontinence
The Immune Reactivity of Biofilms in Vaginal Mesh Erosion.
Aging, birth trauma and extensive pelvic surgery are the causes known to cause advanced pelvic organ prolaspe, fecal as well as urinary incontinence.
- Conditions
- Uterine Prolapse, Urinary Incontinence, Fecal Incontinence
- Trial name
- NCT00564044
- Testing
- excision of the protruding mesh and its surrounding vaginal tissue
- Where
- Taiwan
- Volunteers
- 82 people
- Sponsor
- Chang Gung Memorial Hospital
Prolapse, Vaginal
Vaginal Native Tissues Repair for Pelvic Organ Prolapse
The aim of the study is to assess at one year the effectiveness of the vaginal patch plastron in comparison of the anterior colporraphy through a combined definition of success: anatomic and functional.
- Trial name
- TAPP (NCT03875989)
- Testing
- Anterior colporraphy, vaginal patch plastron
- Where
- 9 sites in France
- Volunteers
- 214 people
- Sponsor
- University Hospital, Limoges
Vaginal Prolapse
Comparison Between Transvaginal Mesh and Traditional Surgery for Pelvic Organ Prolapse
Pelvic organ prolapse is characterized by a lack of pelvic floor support causing the pelvic organs and vaginal walls to protrude.
- Trial name
- NCT00566917
- Testing
- Anterior colporrhaphy, Anterior PROLIFT
- Where
- 53 sites in Denmark, Finland and 2 more
- Volunteers
- 400 people
- Sponsor
- Karolinska Institutet
Genital Diseases, Female, Hysterotomy; Affecting Fetus
Effect of Salpingectomy During Conservative Hysterectomy
The study compares the effect of bilateral salpingectomy associated with conservative hysterectomy on ovarian function to the standard hysterectomy with conservation of both ovaries and tubes in terms of hormone assays, ovarian…
- Conditions
- Genital Diseases, Female, Hysterotomy; Affecting Fetus, Leiomyomata Uteri, Adenomyosis, Endometriosis
- Trial name
- SALPINGOVA (NCT01628432)
- Testing
- conservative hysterectomy I, Conservative hysterectomy II
- Where
- 7 sites in France
- Volunteers
- 350 people
- Sponsor
- University Hospital, Tours
Vaginal Vault Prolapse, Enterocele
Sacrocolpopexy Versus Vaginal Mesh Procedure for Pelvic Prolapse
Pelvic prolapse is one of the most frequent pathology in Gynecology. Recurrency of the prolapse after primary surgery is relatively high, 15-30%.
- Conditions
- Vaginal Vault Prolapse, Enterocele, Uterine Prolapse, Cystocele
- Trial name
- NCT01097200
- Testing
- Elevate mesh, Sacrocolpopexy
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Francisco Carmona
Pelvic Organ Prolapse (POP), Pelvic Organ Prolapse Vaginal Surgery
Urinary Continence After Vaginal Surgery for Genital Prolapse in the Spanish Population.
Surgical correction of pelvic organ prolapse (POP) may be associated with the development of postoperative stress urinary incontinence (SUI).
- Conditions
- Pelvic Organ Prolapse (POP), Pelvic Organ Prolapse Vaginal Surgery, Urinary Incontinence (UI)
- Trial name
- NCT07628036
- Testing
- Vaginal surgery for pelvic organ prolapse
- Where
- 4 sites in Spain
- Volunteers
- 1,042 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Uterine Prolapse, Vault Prolapse, Vaginal
Pectopexy Autologous Vs Mesh
prospective comparative study describing using autologous graft for uterine- vault - cervical suspension vs mesh in treatment of apical prolapse
- Trial name
- NCT06524700
- Testing
- pectopexy mesh, pectopexy autologous
- Where
- 2 sites in Egypt, Saudi Arabia
- Volunteers
- 20 people
- Sponsor
- Ain Shams Maternity Hospital
Pelvic Organ Prolapse, Sexual Dysfunction
The Association of Pelvic Organ Prolapse Severity and Urinary Symptoms and Sexual Function
Women with pelvic organ prolapse often accompany with urinary symptoms or sexual dysfunction, and analyzing the association will be helpful to identify the indication of proper management.
- Conditions
- Pelvic Organ Prolapse, Sexual Dysfunction, Lower Urinary Tract Symptoms
- Trial name
- NCT01776580
- Where
- Taiwan
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Uterine Prolapse, Urine Incontinence
The Assessment of Fibrin Clot Phenotype and Thrombin Generation in Women After Urogynecological Surgeries.
Determination of fibrin clot properties along with thrombin generation in women after urigynecological surgery.
- Trial name
- NCT07295782
- Testing
- determination of fibrin clot properties
- Where
- Poland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Jagiellonian University
Urinary Retention, Uterine Prolapse
Does Spinal Anesthesia for Prolapse Surgery With Lead to Urinary Retention?
The purpose of the study is to compare the risk of being unable to urinate shortly after surgery, also called acute post-operative urinary retention (POUR) between spinal and general anesthesia in women who undergo outpatient…
- Trial name
- NCT02547155
- Testing
- Spinal anesthesia, General anesthesia
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Pelvic Organ Prolapse, Abnormal Uterine Bleeding
Evaluating Artisential Laparoscopic Instruments in Gynecologic Surgery
This study evaluates the efficacy and safety of Artisential laparoscopic instruments in minimally invasive gynecologic surgery.
- Conditions
- Pelvic Organ Prolapse, Abnormal Uterine Bleeding, Mesh Augmentation, Laparoscopic Surgery
- Trial name
- MIGS-ART (NCT06050161)
- Testing
- Articulating laparoscopic instrument, Conventional laparoscopic instrument, Robotic surgical instrument
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Kern Medical Center
Uterine Prolapse
Comparison of Laparoscopic to Vaginal Surgical Repair for Uterine Prolapse
Investigators intend to conduct a prospective randomized trial to compare vaginal hysterectomy with uterosacral colposuspension to laparoscopic supracervical hysterectomy with sacrocervicopexy.
- Trial name
- NCT01594372
- Testing
- Laparoscopic supracervical hysterectomy with sacropexy, Vaginal hysterectomy with uterosacral colposuspension
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Brigham and Women's Hospital
Pelvic Organ Prolapse
Smartmesh Technology in Pelvic Floor Repair Procedures
Pelvic organ prolapse repair involves conservative treatments and surgical treatments. Conservative treatments are for patients with moderate prolapse. Treatment of symptomatic prolapse remains essentially surgical.
- Trial name
- Restorelle (NCT03098641)
- Testing
- pelvic organ prolapse repair
- Where
- 16 sites in France
- Volunteers
- 272 people
- Sponsor
- Groupe Hospitalier de la Rochelle Ré Aunis