Clinical trials: Genitourinary Cancer
Ovarian Cancer
Circulating Lymphatic Progenitor Cell and Lymph Node Metastasis
Correlation of circulating lymphatic endothelial progenitor cells with lymph node metastasis
- Trial name
- NCT01268956
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hospital Universitari de Bellvitge
Cervical Cancer, Postoperative Pelvic Floor Dysfunction
Three-dimensional Study on the Structural Destruction of Pelvic Anatomy in Cervical Cancer
Cervical cancer is one of the most prevalent malignancies in female .To the younger patients, radical hysterectomy which is a standard operation during the earlier and middle therapy stage as well as more effective technique like…
- Trial name
- NCT03155529
- Testing
- radical hysterectomy
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Nanfang Hospital, Southern Medical University
Prostate Cancer
Update and Biodistribution of [F-18]FMDHT pET/CT in Normal Healthy Volunteers and Patients With Metastatic Prostate Cancer - A First in Human Subject Study With [F-18] FMDHT
Prostate cancer represents a significant health problem in the United States. This year 179,000 men in the United States will be diagnosed with prostate carcinoma and approximately 25% of them will die of the disease.
- Trial name
- NCT01724619
- Testing
- [F-18] fluorinated dihydrotestosterone (FDHT)
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Polycystic Ovary Syndrome
Recombinant Versus Highly Purified FSH in Polycystic Ovary Syndrome (PCOS)
Control ovarian stimulation responses, pregnancy and miscarriage rates are indifferent when either recombinant or highly purified follicle stimulating hormone (FSH) is used.
- Trial name
- NCT01337531
- Testing
- Gonal-F, Fostimon
- Where
- Cyprus
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Genesis Center for Fertility & Human Pre-Implantation Genetics
Renal Impairment
Pharmacokinetics in Subjects With Renal Impairment
This is an open-label, non-randomized, parallel-group, mono-center, single intravenous dose, Phase I trial to investigate the Pharmacokinetic (PK) and safety of cilengitide in subjects with different grades of renal impairment as…
- Trial name
- NCT01504165
- Testing
- cilengitide 2000mg, cilengitide 1000mg, cilengitide > 1000mg and up to 2000mg
- Where
- 2 sites in Germany
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Merck KGaA, Darmstadt, Germany
Human Papilloma Virus Infection, Cervical Intraepithelial Neoplasia Grade 2/3
The HPV Self-test as a Test of Cure in Madagascar
The purpose of this study is to find out whether Self-HPV may be an accurate method for the follow-up of women with a history of HPV infection.
- Trial name
- NCT02811367
- Testing
- HPV test
- Where
- Madagascar
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- University Hospital, Geneva
Ovarian Cancer, Caregiver Burden
Multidimensional Burden of Platinum Resistant Ovarian Cancer (PROC) on Patients and Caregivers in Canada
Filling the gap in Canadian evidence on the burden of PROC on QoL is essential. It will help better understand the impact of PROC on multiple aspects of the lives of patients and their caregivers and the real-life hurdles faced…
- Conditions
- Ovarian Cancer, Caregiver Burden, Patient Burden
- Trial name
- NCT07035067
- Testing
- No intervention
- Where
- Canada
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- PeriPharm
Hot Flashes
Effect of Soy on Cognition and Hot Flashes in Men With Prostate Cancer Undergoing Testosterone Suppression Therapy
This study will look at the effects of a soy supplement called Revival on memory, quality of life, and hot flashes in men with prostate cancer who are being treated with testosterone suppression therapy.
- Trial name
- NCT00245518
- Testing
- Isoflavone
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Bladder Cancer
Paclitaxel-binding Albumin and Cisplatin as Neoadjuvant Chemotherapy in Patients With Muscle-Invasive Bladder Cancer
This is a phase II study of Paclitaxel-binding albumin, Cisplatin as neoadjuvant chemotherapy in patients with muscle-invasive urothelial carcinoma of the bladder.
- Trial name
- NCT04060459
- Testing
- Paclitaxel-binding albumin
- Where
- China
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Third Military Medical University
Human Papillomavirus Infection
Quality Improvement Strategies to Increase Human Papillomavirus (HPV) Vaccination
HPV vaccination is at lower levels than the national goals. This study will evaluate the effectiveness of quality improvement strategies for increasing HPV vaccination coverage among adolescents in primary care clinics.
- Trial name
- NCT03442062
- Testing
- Assessment Feedback Incentives and eXchange, Physician-to-physician engagement, Active Intervention Control
- Where
- 3 sites in United States
- Volunteers
- 264 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Ovarian Cancer
Salpingectomy at Cesarean Delivery for Ovarian Cancer Reduction (SCORE)
To compare the feasibility and surgical outcomes between complete salpingectomy and standard postpartum tubal ligation (partial salpingectomy) at the time of cesarean delivery in women with undesired future fertility.
- Trial name
- SCORE (NCT02374827)
- Testing
- Standard postpartum tubal ligation, Complete Salpingectomy
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Dengue, Chikungunya
Risk Assessment of Community Spread of Multiple Endemic Infectious Diseases in a One Health Perspective
RACSMEI addresses the high burden of infectious diseases in low- and middle-income countries, including Cambodia, where limited surveillance and laboratory capacity often obscure etiologies and transmission dynamics.
- Conditions
- Dengue, Chikungunya, Zika Virus Infection, Japanese Encephalitis
- Trial name
- RACSMEI (NCT07358910)
- Where
- Cambodia
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Institut Pasteur du Cambodge
Prostate Cancer
Prostate Cancer Prospective Cohort
The overall purpose of this research is to determine if certain genes increase the chance of developing prostate cancer and once diagnosed increase the chance of the prostate cancer spreading to other parts of the body.
- Trial name
- NCT00937586
- Where
- United States
- Volunteers
- 1,937 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Breast Cancer, Ovarian Cancer
Genetic Risk Assessment for Cancer Education and Empowerment (GRACE) Project
GRACE is a randomized 3-arm trial to determine the comparative effectiveness of two remote cancer communication interventions: 1) a targeted generic print (TP) or 2) a tailored telephone-based counseling and navigation…
- Trial name
- GRACE (NCT03326713)
- Testing
- Telephone Counseling & Navigation (TCN), Mailed Targeted Print (TP), Usual Care (UC)
- Where
- United States
- Volunteers
- 668 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Benign Prostatic Hyperplasia, Prostatitis
2013 Annual National Digital Rectal Exam (DRE) Day Study
We aim to determine the effectiveness of 2013 "Mag paDRE ka" programme in increasing general public awareness on prostate health and promoting prostate health assessment among Filipino males aged 40 or older.
- Conditions
- Benign Prostatic Hyperplasia, Prostatitis, Prostate Cancer
- Trial name
- NCT01886547
- Testing
- Prostate health screening
- Where
- Philippines
- Volunteers
- 925 people, healthy volunteers welcome
- Sponsor
- St. Luke's Medical Center, Philippines
Human Papillomavirus Infection
An Observational, Epidemiological Study on the Prevalence of Human Papillomavirus Types in Women in Egypt
The purpose of the study is to determine the Human Papillomavirus (HPV) prevalence and HPV type distribution among women aged >= 18 years, attending out-patient health services for gynaecological examination and who agree to HPV…
- Trial name
- NCT01158209
- Testing
- Endocervical samples
- Where
- 2 sites in Egypt
- Volunteers
- 490 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Effects of Chemotherapy, Premature Ovarian Failure
Ovarian Reserve After Cancer: Longitudinal Effects
Women of reproductive age who will receive treatment for cancer that includes chemotherapy may participate in a study measuring ovarian function over time.
- Trial name
- ORACLE (NCT02467231)
- Where
- United States
- Volunteers
- 196 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Prostate Cancer
Study of Erlotinib in Patients With Non-Metastatic Prostate Cancer With a Rising Prostate Specific Antigen (PSA) on Hormone Therapy
The primary objective of this study is to evaluate the effect of erlotinib on the PSA response rate in patients with non-metastatic prostate cancer and a rising PSA on androgen deprivation therapy.
- Trial name
- NCT00148772
- Testing
- Erlotinib (Tarceva)
- Where
- 2 sites in United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Endeavor Health
Papillomavirus Infections
The KEN SHE Study on HPV-vaccine Efficacy
The KEN SHE Study aims to identify effective cervical cancer prevention strategies. Cervical cancer is caused by an infection with Human Papillomavirus, also called HPV.
- Trial name
- NCT03675256
- Testing
- immediate Gardasil 9, delayed MenVeo vaccine, immediate MenVeo vaccine, delayed Gardasil 9, immediate Cervarix, delayed MenVeo vaccine
- Where
- 3 sites in Kenya
- Volunteers
- 2,275 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Cervical Intraepithelial Neoplasia, Cervical Cancer
The Development of a "Mother/Child, Screen, Treat and Vaccinate Program" in Manchay and Iquitos, Peru
This project will use a community based participatory research orientation to develop a model for large scale "campaign" preventive healthcare interventions.
- Conditions
- Cervical Intraepithelial Neoplasia, Cervical Cancer, Cervical Neoplasm, Cervical Dysplasia
- Trial name
- PERCAPS (NCT01338051)
- Testing
- Gardasil
- Where
- 2 sites in Peru
- Volunteers
- 642 people, healthy volunteers welcome
- Sponsor
- Preventive Oncology International, Inc.
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