Clinical trials: Genitourinary Cancer
Hereditary Breast and Ovarian Cancer Syndrome
Search Allelic Imbalance of Expression of BRCA Genes in Hereditary Risk of Breast and/or Ovarian Cancer
The purpose of this study is to determine proportion of patients presented a search allelic imbalance of expression of genes BRCA 1 and 2 in population with hereditary breast and/or ovarian cancer risk and negative for deletion…
- Trial name
- EXSAL (NCT01333748)
- Testing
- blood collection
- Where
- 6 sites in France
- Volunteers
- 530 people, healthy volunteers welcome
- Sponsor
- Centre Francois Baclesse
Safety Issues, HPV Infection
BS-FU01 Follow-Up Study of FluBHPVE6E7 Study Subjects
This is a follow-up study for patients treated with FluBHPVE6E7 in previous interventional studies.
- Trial name
- NCT04528407
- Testing
- Observation without intervention
- Where
- Austria
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- BlueSky Immunotherapies GmbH
Cervical Cancer, Anogenital Warts
Evaluation of Long Term Immunity Following HPV Vaccination
In Fiji, cervical cancer is the second most frequent cancer and the highest cause of cancer mortality in women. In 2008/9, the Ministry of Health in Fiji accepted a donation of 110,000 doses of quadrivalent HPV vaccine, Gardasil®…
- Trial name
- NCT02276521
- Testing
- Cervarix®
- Where
- Fiji
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Murdoch Childrens Research Institute
Urinary Incontinence, Prostate Cancer
Perioperative Post-Prostatectomy Incontinence Home Telehealth Program
Many men develop urine leakage after prostate cancer surgery. Usually it is temporary, but pelvic floor muscle training and exercise (including urine control strategies) have been shown to reduce the time to regaining urine…
- Trial name
- ProsTel (NCT01960998)
- Testing
- Pelvic Floor Muscle Training, Perioperative Care and Wetness Management
- Where
- 3 sites in United States
- Volunteers
- 245 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Prostate Carcinoma
Genetic Information to Inform Treatment and Screening for Prostate Cancer, GIFTS Study
This trial studies the role of inherited (present at birth) mutations in cancer risk genes such as BRCA2, BRCA1, ATM, CHEK2, and others in relation to prostate cancer.
- Trial name
- GIFTS (NCT04254133)
- Testing
- Questionnaire, Biospecimen Collection, Genetic Testing
- Where
- United States
- Volunteers
- 1,360 people, healthy volunteers welcome
- Sponsor
- Fred Hutchinson Cancer Center
Benign Prostatic Hyperplasia, Prostatitis
2013 Annual National Digital Rectal Exam (DRE) Day Study
We aim to determine the effectiveness of 2013 "Mag paDRE ka" programme in increasing general public awareness on prostate health and promoting prostate health assessment among Filipino males aged 40 or older.
- Conditions
- Benign Prostatic Hyperplasia, Prostatitis, Prostate Cancer
- Trial name
- NCT01886547
- Testing
- Prostate health screening
- Where
- Philippines
- Volunteers
- 925 people, healthy volunteers welcome
- Sponsor
- St. Luke's Medical Center, Philippines
Prostatic Neoplasm, Urinary Bladder Neoplasm
The Effect of Prolonged Inspiratory Time on Gas Exchange During Robot-assisted Laparoscopic Surgery With Steep Trendelenburg Position : A Crossover Randomized Clinical Trial
Gas exchange disturbance frequently occurs in steep Trendelenburg position during robot-assisted laparoscopic prostatectomy or cystectomy.
- Trial name
- NCT02966535
- Testing
- Adjustment of Mechanical Ventilator Inspiratory to expiratory time ratio (1:2 to 1:1), Adjustment of Mechanical Ventilator Inspiratory to expiratory time ratio (1:1 to 1:2)
- Where
- South Korea
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
WAGR Syndrome, Wilm's Tumor
Characterization of WAGR Syndrome and Other Chromosome 11 Gene Deletions
This study will explore conditions caused by the absence of certain genes on chromosome 11. These conditions include WAGR syndrome, which is characterized by a kidney tumor called Wilm s tumor, aniridia (absence of the iris of…
- Conditions
- WAGR Syndrome, Wilm's Tumor, Aniridia, Urogenital Abnormalities
- Trial name
- NCT00758108
- Where
- United States
- Volunteers
- 197 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Breast Carcinoma, Cervical Carcinoma
The Ohio State University (OSU) SCREEN Community Program
This clinical trial develops and tests how well a multi-level intervention (MLI), The Ohio State University (OSU) SCREEN Community Program, works to increase screening and follow-up for breast, cervical and colorectal (CRC)…
- Conditions
- Breast Carcinoma, Cervical Carcinoma, Colorectal Carcinoma
- Trial name
- NCT06666192
- Testing
- Cancer Screening, Discussion, Educational Activity
- Where
- United States
- Volunteers
- 2,067 people, healthy volunteers welcome
- Sponsor
- Ohio State University Comprehensive Cancer Center
Cervical Cancer
Effects of Decision Aids on the Participation of South Asian Women in Cervical Cancer Screening
Objectives: To examine the effects of linguistically appropriate decision aids on decisional conflicts, risk perception, clarity of values, screening decisions and screening uptake among South Asian women in Hong Kong Design and…
- Trial name
- NCT06069648
- Testing
- printed screening decision aid, a leaftlet, mobile screening decision aid
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Human Papillomavirus Infection, Cervical Cancer
Clinical Evaluation of Detection of High Risk HPV in Urine
Cervical cancer is one of the most common tumors in women, which seriously threatens women's life quality and safety. Human papilloma virus (HPV) infection is the most common cause of cervical cancer.
- Conditions
- Human Papillomavirus Infection, Cervical Cancer, Human Papilloma Virus, Negative for Intraepithelial Lesion or Malignancy
- Trial name
- Urine-hrHPV (NCT05210348)
- Where
- 3 sites in China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Peking University People's Hospital
Prostate Cancer
Randomized Phase II Trial of Targeted Radiation With no Castration for Mcrpc
This trial tests if the combination of comprehensive metastasis directed therapy delivered by a precision form of external beam radiotherapy (stereotactic ablative radiotherapy), combined with PSMA targeted radiopharmaceutical…
- Trial name
- NCT06084338
- Testing
- stereotactic ablative radiotherapy, Pluvicto, topical testosterone
- Where
- 4 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Prostate Cancer
Facilitating Participation in a Prostate Cancer Risk Assessment Program
The purpose of this study was to examine whether a cognitive-affective preparation was more beneficial, in general, and more specifically for certain subgroups, such as African-American men and individuals with high monitoring…
- Trial name
- NCT02126319
- Testing
- Cognitive Affective preparation, General Health Education
- Where
- United States
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Fox Chase Cancer Center
HPV Infection, HPV 16 Infection
Evaluation of the Q-Pad hrHPV Test System for Identifying Precancer
The EQUIP Study is testing whether high-risk human papillomavirus (hrHPV), the virus that causes most cervical cancers, can be accurately detected from menstrual blood collected at home.
- Conditions
- HPV Infection, HPV 16 Infection, High Risk HPV, Cervical Cancer Screening
- Trial name
- EQUIP (NCT07281599)
- Testing
- Q-Pad hrHPV Test System
- Where
- 3 sites in United States
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Qurasense
Polycystic Ovary Syndrome, Hyperandrogenism
Urinary DENND1A.V2 as a Predictor of Pubertal Hyperandrogenemia
Polycystic ovary syndrome (PCOS) is a common disorder marked by hyperandrogenism, oligo-/anovulation, and subfertility. The precise causes of PCOS are unclear, but the pathophysiology involves complex genetic and environmental…
- Conditions
- Polycystic Ovary Syndrome, Hyperandrogenism, Puberty
- Trial name
- DENND1A (NCT02611128)
- Testing
- Phenotype/genotype assessment
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Prostate Cancer
A Pilot Study of Prostate Cancer-specific Anxiety in Active Surveillance
This study is a clinical trial to determine whether a 12-week group therapy intervention for patients undergoing Active Surveillance for Prostate Cancer can relieve disease-related anxiety and improve quality of life and delay…
- Trial name
- NCT03227744
- Testing
- Group therapy, Surveys
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Prostate Cancer
Multi-Modal Image Fusion for Precision Prostate Biopsy Navigation
This study is a prospective randomized controlled clinical trial aimed at comparing the detection rates of clinically significant prostate cancer between conventional biopsy methods and AI-assisted biopsy methods in patients…
- Trial name
- NCT06441292
- Testing
- AI-assisted, Non-AI-assisted
- Where
- China
- Volunteers
- 602 people, healthy volunteers welcome
- Sponsor
- Shanghai East Hospital
Polycystic Ovary Syndrome
Induction of Ovulation With Raloxifene or Clomiphene Citrate in Polycystic Ovarian Syndrome
The Polycystic Ovarian Syndrome (PCOS) is a common disorder related to ovulation problems. Clomiphene citrate (CC) is the drug of first choice for this condition.
- Trial name
- NCT00427700
- Testing
- clomiphene citrate, raloxifene
- Where
- Brazil
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Hospital de Clinicas de Porto Alegre
Chronic Pancreatitis, Inflammatory Bowel Diseases
Genomic Resources for Enhancing Available Therapies (GREAT1.0) Study
This is a prospective, descriptive, observational research study designed to observe and document the clinical practice by domain experts, and how the knowledge of new findings that are published in the medical literature affect…
- Conditions
- Chronic Pancreatitis, Inflammatory Bowel Diseases, Hepatitis, NASH - Nonalcoholic Steatohepatitis
- Trial name
- GREAT1 (NCT04306939)
- Testing
- venipuncture, Questionnaires, Additional Sample Collections
- Where
- United States
- Volunteers
- 120,000 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Cervical Cancer, Precancerous Condition
Fluorescence and Reflectance Spectroscopy During Colposcopy in Detecting Cervical Intraepithelial Neoplasia and Dysplasia in Healthy Participants With a History of Normal Pap Smears
RATIONALE: New diagnostic procedures such as fluorescence and reflectance spectroscopy (shining light on tissue and measuring patterns of light reflected) may improve the ability to noninvasively detect cervical intraepithelial…
- Trial name
- NCT00084903
- Testing
- Colposcopic biopsy, Light-Scattering Spectroscopy
- Where
- 2 sites in United States, Canada
- Volunteers
- 1,070 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
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