Clinical trials: Genitourinary Cancer
Uterine Cervical Neoplasms
Clinical Study on the Evaluation of the Efficacy of Cervical Cancer
The main objectives of this study are to construct a multi-omics-based prognostic and side-effect prediction model for cervical cancer based on pre-treatment imaging, digital pathology, genomics, proteomics, molecular biology…
- Trial name
- EECC (NCT06254729)
- Testing
- Observational study
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Prostate Cancer
Combined Prostate-specific Antigen, Multi-parametric MRI and Targeted Prostate Biopsy for Prostate Cancer Screening
The study aims to investigate the incidence of prostate cancer among males in Nanjing and whether a combination of PSA, multi-parametric MRI and targeted biopsy is a feasible approach for screening prostate cancer in China.
- Trial name
- NCT04322045
- Testing
- multi-parametric MRI
- Where
- China
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Human Papillomavirus, Cervical Intraepithelial Neoplasia
Evaluating the 2-dose Immunization Schedule of Human Papillomavirus (HPV)-16/18 in Adolescent Females
To evaluate the immune non-inferiority, as measured by antibody responses, of a 2-dose immunization schedule (0, 6 months) of recombinant human papillomavirus virus-like particle vaccine (type 16 and 18 L1 proteins, yeast)…
- Conditions
- Human Papillomavirus, Cervical Intraepithelial Neoplasia, Persistent Infection
- Trial name
- NCT02740777
- Testing
- HPV-16/18 vaccine
- Where
- 2 sites in China
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- Shanghai Zerun Biotechnology Co.,Ltd
Bladder Cancer
Analysis of Urinary Methylation Patterns Via Liquid Biopsy as an Early Diagnosis Tool
Multicenter, observational, prospective, biological pilot study on liquid biopsy, aimed at investigating methylation profiles in relation to the early diagnosis of bladder cancer, to validate the potential of commercially…
- Trial name
- NCT06878027
- Where
- Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Regina Elena Cancer Institute
Endometrial Cancer
Physical Activity After Endometrial Cancer
Researchers propose to apply Social Cognitive Theory to improve understanding of the mechanisms of physical activity adherence for endometrial cancer survivors participating in a physical activity intervention.
- Trial name
- NCT00501761
- Testing
- Personalized Exercise Program, Questionnaire, Suggested Exercise Program
- Where
- United States
- Volunteers
- 326 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Prostate Cancer
Epidemiologic, Clinical and Genetic Profile of Prostate Cancer in Arab Countries
This protocol is designed to collect a small amount of blood and tissue from individuals with prostate cancer for extraction of DNA (genetic material) for the study of the genetic basis of prostate cancer.
- Trial name
- ProstateCA (NCT00801996)
- Where
- Qatar
- Volunteers
- healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Human Papillomavirus 16, Human Papillomavirus 18
Integrated Cervical Cancer Screening in Mayuge District Uganda (ASPIRE Mayuge)
The purpose of this pragmatic cluster randomized control trial is to test the effectiveness of cervical cancer screening follow-up completion using two implementation approaches for self-collected HPV testing in a rural…
- Conditions
- Human Papillomavirus 16, Human Papillomavirus 18, Papillomavirus Infections, Cervical Cancer
- Trial name
- ASPIRE (NCT04000503)
- Testing
- Self-collected HPV testing for cervical cancer screening
- Where
- Uganda
- Volunteers
- 2,019 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Breast Carcinoma, Cervical Carcinoma
CATCH-UP Intervention in Increasing Cancer Screening and Prevention Care in Uninsured Patients at Community Health Centers
This randomized research trial studies the Community-based Health Information Technology (HIT) Tools for Cancer Screening and Health Insurance Promotion (CATCH-UP) intervention in increasing cancer screening and prevention care…
- Conditions
- Breast Carcinoma, Cervical Carcinoma, Colorectal Carcinoma, Health Status Unknown
- Trial name
- NCT02355262
- Testing
- Informational Intervention
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- OHSU Knight Cancer Institute
Urinary Bladder Neoplasms
Narrow-band Imaging Diagnostic Classification System for Bladder Tumors
The goal of this observational study is to learn about the morphological characteristics of different bladder lesions under narrow-band imaging（NBI） techniques in All patients requiring cystoscopy and biopsy.
- Trial name
- NBI (NCT05611762)
- Where
- China
- Volunteers
- 1,064 people, healthy volunteers welcome
- Sponsor
- Qilu Hospital of Shandong University (Qingdao)
Cervical Cancer
A Novel Smart Speculum Versus a Standard Speculum for Easy Visualisation of the Cervix and Performing Remote Cervical Cancer Screening
Objective: The main objective of this study is to verify the level of comfort for patients and the degree of cervical visibility for health providers using a novel smart speculum compared to the standard speculum.
- Trial name
- NCT06359431
- Testing
- Novel Smart Speculum, Standard speculum
- Where
- Cameroon
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- GICMED
Intestinal Microbiota, Vaginal Microbiota
Characteristics of Vaginal and Intestinal Microbiota and Cervical HPV Infection
There are different microbial communities on the surface of human body (skin, hair, nails, etc.) and in the cavity connected with the outside world.
- Conditions
- Intestinal Microbiota, Vaginal Microbiota, HPV Infection
- Trial name
- NCT05003505
- Testing
- Follow up
- Where
- 8 sites in China
- Volunteers
- 651 people, healthy volunteers welcome
- Sponsor
- Fujian Maternity and Child Health Hospital
Fibroid Uterus, Endometriosis
ICG to Assess Ovarian Perfusion
To assess the feasibility of using intravenous ICG to characterize the vascular perfusion of ovaries during gynecologic surgery
- Conditions
- Fibroid Uterus, Endometriosis, Uterus Myoma, Uterine Fibroid
- Trial name
- NCT03927651
- Testing
- ICG
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Dementia, Diabetes Mellitus
Impact of Lifestyle Modification on the Development of Dementia, Chronic Kidney Disease, Diabetes, Chronic Obstructive Pulmonary Disease, Cancers and Cardiovascular Disease in a Thai General Population
This is a community-based cluster randomized control trial aimed to investigate the impact of lifestyle modification (diet, physical activity, alcohol drinking and smoking) on the development of dementia, diabetes, chronic kidney…
- Conditions
- Dementia, Diabetes Mellitus, Chronic Kidney Disease, Cardiovascular Diseases
- Trial name
- NCT02967406
- Testing
- 4 x 4 lifestyle modification
- Where
- Thailand
- Volunteers
- 3,600 people, healthy volunteers welcome
- Sponsor
- Sanpasitthiprasong Hospital
Cancer-related Cognitive Impairment
Testosterone, Cognition, Ageing, and Cancer
The primary aim of the study is - in a prospective controlled design - to examine whether treatment-induced decreases in testosterone acts as a mechanism of cancer-related cognitive impairment (CRCI) in testicular and prostate…
- Trial name
- NCT03452436
- Where
- Denmark
- Volunteers
- 133 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Bladder Cancer
Expression of MCM5 in Urine in Patients With Urothelial Cancers
In patients with non-muscle-invasive bladder cancer, the development and introduction to the clinical practice of an adequately accurate biomarker may allow to limit the indications for performing control cystoscopy.
- Trial name
- NCT03796299
- Testing
- Assessment of expression of MCM5 in the urine (ADX Bladder)
- Where
- Poland
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Medical University of Warsaw
Effects of Chemotherapy
Assessing Fertility Potential in Female Cancer Survivors
Hypothesis: Girls and women exposed to chemotherapy and/or radiation therapy experience endocrine changes more similar to women in their late reproductive years than to same-age peers.
- Trial name
- NCT01143844
- Where
- 2 sites in United States
- Volunteers
- 391 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Prostatic Neoplasms, PSA
Prostate Impendance Test Project
Impedance-based analysis could provide an adequate response to the need to identify a safe and reliable tool alternative to bioptic diagnosis.
- Conditions
- Prostatic Neoplasms, PSA, Prostatic Biopsy, Impedance Test
- Trial name
- PROSIT (NCT03428087)
- Where
- Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Pisa
Stage 0a Bladder Cancer AJCC v8, Stage 0is Bladder Cancer AJCC v8
Behavioral Dietary Intervention for the Improvement of Bladder Cancer Survivorship
This phase I trial investigates how well a healthy eating program works in improving outcomes in patients with bladder cancer. The behavioral dietary program consists of educational materials, live phone calls, and interactive…
- Conditions
- Stage 0a Bladder Cancer AJCC v8, Stage 0is Bladder Cancer AJCC v8, Stage I Bladder Cancer AJCC v8
- Trial name
- NCT04548193
- Testing
- Behavioral Dietary Intervention, Educational Intervention, Questionnaire Administration
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Roswell Park Cancer Institute
Polycystic Ovary Syndrome, Premenstrual Syndrome
Effects of a Female Hormone Balance Supplement on Symptoms of Polycystic Ovary Syndrome and Severe Premenstrual Syndrome
This is a virtual single group study that will last 12 weeks. Participants will take 1 scoop of the female hormone balance supplement, and mix it with their drink of choice every morning.
- Trial name
- NCT06124300
- Testing
- Female Hormone Balance Supplement
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Rael
HPV Infection, HSIL, High-Grade Squamous Intraepithelial Lesions
A Multicenter Cohort Study of HPV Viral Load in Predicting the Postoperative Recurrence of HSIL
Human papillomavirus (HPV) infection has become one of the most important health problems faced by women all over the world. A large number of studies have shown that women's cervical, vaginal and perianal precancerous lesions…
- Conditions
- HPV Infection, HSIL, High-Grade Squamous Intraepithelial Lesions, Viral Load
- Trial name
- NCT05282745
- Testing
- Follow-up
- Where
- 10 sites in China
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- Fujian Maternity and Child Health Hospital
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.