Clinical trials: Genitourinary Disease
Newborn Care, Pain Management
The Effect of Breast Milk, 10% and 20% Dextrose on Pain and Physiological Variables During Heel Puncture in Infants
Pain, defined by the International Association for the Study of Pain as a subjective, sensory, and emotional experience, differs from nociception, which is merely a neural activity.
- Conditions
- Newborn Care, Pain Management, Physiological Parameters During Newborn Care İn Newborn's, Breast Milk
- Trial name
- NCT07716813
- Testing
- Administering oral breast milk in a supportive position, Administering oral 10% dextrose in a supportive position, Administering oral 20% dextrose in a supportive position
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people
- Sponsor
- Mersin University
Autosomal Dominant Polycystic Kidney Disease
The ELiSA Study - Evaluation of Lixivaptan in Subjects With Autosomal Dominant Polycystic Kidney Disease
This is a Phase 2, open-label, parallel-group, multiple dose study designed to evaluate the pharmacokinetics, pharmacodynamics, safety and tolerability of multiple doses of lixivaptan in Autosomal Dominant Polycystic Kidney…
- Trial name
- NCT03487913
- Testing
- Lixivaptan
- Where
- 13 sites in United States
- Volunteers
- 31 people
- Sponsor
- Palladio Biosciences
Depression, Postpartum, Maternal Behavior
The Effect of Baby Massage on Postpartum Depression and Maternal Attachment
This study was conducted to determine the effect of baby massage on postpartum depression and maternal attachment in the postpartum period.
- Conditions
- Depression, Postpartum, Maternal Behavior, Attachment
- Trial name
- NCT05813782
- Testing
- Baby Massage
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University
HIV Seropositivity, Opioid-use Disorder
Implementation of STTR Strategies Among People Who Inject Drugs in Malaysia
This pragmatic, multisite, implementation and effectiveness research evaluates a strategy to improve HIV treatment outcomes (increased rates of patients on ART with virological suppression, improved treatment retention and ART…
- Trial name
- NCT03987282
- Testing
- Enhanced usual care (EUC), Peer-based counseling
- Where
- Malaysia
- Volunteers
- 2 people
- Sponsor
- Yale University
Hematuria, Nephrolithiasis
Diagnostic Relevance of Laser Confocal Microscopy for the Screening of Upper Urinary Tract Tumors
Upper Urinary Tract Tumors have an incidence of 1 to 2 cases for 100 000 persons per year. The standard treatment for these tumors is the ablation of the kidney, ureter and a part of the bladder surrounding the ureteral orifice.
- Conditions
- Hematuria, Nephrolithiasis, Cancer of Urinary Tract, Ureteropelvic Junction Obstruction
- Trial name
- UROVISIO (NCT02276924)
- Testing
- Laser confocal microscopy
- Where
- France
- Volunteers
- 29 people
- Sponsor
- Lille Catholic University
Dysfunction; Endocrine, Effects of Chemotherapy
Blood Spot Self-administered Test and Assay
The current study will compare hormone levels of AMH, FSH and inhibin B in blood specimens collected by venipuncture and fingerstick in a sample of pre-menopausal women ages 18-45 years with normal menstrual cycles.
- Conditions
- Dysfunction; Endocrine, Effects of Chemotherapy, Premature Ovarian Failure
- Trial name
- NCT03840824
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Erectile Dysfunction
A Study to Evaluate the Safety and Effectiveness of Mirodenafil in Korean Patients With Erectile Dysfunction
The purpose of this study is to evaluate the safety and effectiveness of mirodenafil in participants with erectile dysfunction.
- Trial name
- NCT01802359
- Testing
- No intervention
- Volunteers
- 379 people
- Sponsor
- Janssen Korea, Ltd., Korea
Bladder Cancer
The iBlad App - a National, Exploratory Study on a Multimodality Smartphone App for Bladder Cancer Patients
The aims of this project are: to develop and implement a national multimodality application for patients with bladder cancer that builds upon knowledge from the iBLAD study.
- Trial name
- iBLAD-app (NCT05710159)
- Testing
- iBLAD Application to monitor symptoms and quality of life by the use of pateint-reported outcomes
- Where
- 2 sites in Denmark
- Volunteers
- 100 people
- Sponsor
- Odense University Hospital
Gynecologic Cancer, Colorectal Cancer
Long-Term Follow-up Study of Subjects Treated With Autologous T Cells Using the Sleeping Beauty System to Express TCRs
Long-Term Follow-Up Study for Subjects Enrolled in the Phase I/II Study of Autologous T Cells Engineered using the Sleeping Beauty System to Express T cell Receptors (TCRs) Reactive Against Cancer-specific Mutations in Subjects…
- Conditions
- Gynecologic Cancer, Colorectal Cancer, Pancreatic Cancer, Non-small Cell Lung Cancer
- Trial name
- NCT05292859
- Testing
- Neoantigen specific TCR-T cell drug product
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Alaunos Therapeutics
Cancer Prevention
Accelerating the Implementation of a Breast and Cervical Cancer Screening and HPV Vaccination Intervention
The proposed study will develop and test an implementation strategy called Salud en Mis Manos-Dissemination and Implementation Assistance (SEMM-DIA) which is an internet-accessible cross-platform that includes additional…
- Trial name
- NCT05524480
- Testing
- Salud en Mis Manos - Dissemination and Implementation Assistance, Salud en Mis Manos- Usual Implementation Practice
- Where
- United States
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Anemia of End Stage Renal Disease
TARGTEPO Treatment for Anemia in End Stage Renal Disease (ESRD) Patients Undergoing Peritoneal Dialysis (PD)
The objectives of this study are to assess safety and to evaluate the biologic activity of TARGTEPO treatment in Peritoneal Dialysis patients
- Trial name
- NCT02378662
- Testing
- MDGN201 TARGTEPO
- Where
- 2 sites in Israel
- Volunteers
- 2 people
- Sponsor
- Aevi Genomic Medicine, LLC, a Cerecor company
Infertility
Fast Track to Fertility
The Fast Track to Fertility (FTF) program is an algorithmic text messaging communication and patient education platform designed to improve the efficiency the fertility workup.
- Trial name
- FTFRCT (NCT07154888)
- Testing
- Fast Track to Fertility Algorithmic Text Messaging Platform
- Where
- United States
- Volunteers
- 162 people
- Sponsor
- University of Pennsylvania
Prostate Cancer, Adenocarcinoma of the Prostate
Neoadjuvant Bevacizumab Plus Docetaxel in High Risk Patients With Prostate Cancer Undergoing Radical Prostatectomy
The main purpose of this trial is to collect information and to evaluate the effects, good or bad, the combination of docetaxel and bevacizumab has on patients with high risk prostate cancer that are undergoing radical…
- Trial name
- NCT00321646
- Testing
- Bevacizumab, Docetaxel
- Where
- 3 sites in United States
- Volunteers
- 42 people
- Sponsor
- Mary-Ellen Taplin, MD
Gout, Renal Insufficiency
Optimal Administration of Allopurinol in Dialysis Patients
Gout has a strong association with the metabolic syndrome, and it is often seen in patients with renal insufficiency. Allopurinol is a medication intended to lower uric acid and therefore prevents gout attacks.
- Trial name
- NCT02477488
- Testing
- Allopurinol
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- Maisonneuve-Rosemont Hospital
Placebo Analgesia
Oxytocin and Arginine Vasopressin in Pain Relief
Background: Oxytocin, a substance produced mostly in the brain, plays a role in influencing social interactions and reactions to stress, and may be related to pain.
- Trial name
- NCT01328561
- Where
- United States
- Volunteers
- 167 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
HIV Infections, Hepatitis B
Hepatitis B Vaccination in HIV-infected Persons
In this study we compare the efficacy of two different HBV-vaccination schedules in HIV-infected persons concerning immune response and compliance. Short schedule: t=0,1,3 weeks and standard schedule: t=0,1,6 months.
- Trial name
- NCT00230061
- Testing
- HBVAXPRO, Hepatitis B (Recombinant) vaccine, 10 mcg/ml
- Where
- Netherlands
- Volunteers
- 800 people
- Sponsor
- Erasmus Medical Center
Prostate Cancer
Early Changes In Multiparametric MRI In Prostate Cancer
In this research study, the investigators are trying to determine if there are measurable changes in prostate MRI that will help predict those who will or will not respond to Androgen Deprivation Therapy (ADT) and External Beam…
- Trial name
- NCT01959542
- Testing
- MRI, PSA Blood Test
- Where
- 2 sites in United States
- Volunteers
- 15 people
- Sponsor
- Dana-Farber Cancer Institute
Ovarian Cancer
Study Comparing Weekly Versus Every 3 Week Chemotherapy in Patients With Ovarian Cancer
The purpose of this study is to study efficacy and the effects on quality of life in women with ovarian cancer treated with a weekly schedule of chemotherapy with carboplatin and paclitaxel compared to those treated with standard…
- Trial name
- MITO-7 (NCT00660842)
- Testing
- carboplatin, paclitaxel
- Where
- 28 sites in Italy
- Volunteers
- 800 people
- Sponsor
- National Cancer Institute, Naples
Sleep Wake Disorders, Sleep Initiation and Maintenance Disorders
AI-Powered Sleep Hygiene Mentor for Adults Living With HIV
Poor sleep is common among people living with HIV and is linked to fatigue, psychological distress and poorer adherence to antiretroviral therapy.
- Conditions
- Sleep Wake Disorders, Sleep Initiation and Maintenance Disorders, HIV Infections
- Trial name
- NCT07894042
- Testing
- AI-powered sleep hygiene mentor
- Where
- Indonesia
- Volunteers
- 100 people
- Sponsor
- Universitas Indonesia
End-stage Renal Disease
Sodium Chloride and Protein-Bound Toxin Removal in Hemodiafiltration
An increase of the free fraction may allow a better removal of of protein-bound uremic toxins during dialysis. During predilution hemodiafiltration, the sodium chloride (NaCl) concentration will be increased in the infusion fluid…
- Trial name
- NCT01923961
- Testing
- HDF NaCl, Hemodialysis, Standard Predilution Hemodiafiltration
- Where
- Germany
- Volunteers
- 8 people
- Sponsor
- EXcorLab GmbH
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