Clinical trials: Geriatric
Type 2 Diabetes Mellitus (T2DM), Cognitive Function
Prediabetes and Type 2 Diabetes in Aging
This case-control study will evaluate the effects of geriatric individuals on cognitive status, physical function and fatigue. Our study aims to compare the effects of geriatric individuals with prediabetes and type 2 diabetes…
- Conditions
- Type 2 Diabetes Mellitus (T2DM), Cognitive Function, Dual Task, Fatigue
- Trial name
- NCT06953609
- Where
- Turkey (Türkiye)
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Uşak University
Hospital Foodservice Satisfaction; Hospital Meals Satisfaction; Elderly, Nutrition, Malnutrition in Elderly, Malnutrition
A Logical Framework for Tailor-made Paradigm Shift Hospital Foodservice to Prevent Malnutrition Among Geriatric Patients in Hospitals
Hospital Food service is important for patient recovery by providing necessary aid with adequate meal consumption. Overall, hospital experience can influence patients' satisfaction for the foodservice quality.
- Trial name
- NCT04858165
- Testing
- MY GERYFS PROTOCOL
- Where
- 5 sites in Malaysia
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Universiti Putra Malaysia
Measles
Study to Evaluate Safety, Dose Response and Immunogenicity of the Measles Vaccine MVA mBN85B in Healthy Children Aged 6 Months to 6 Years
Partially randomized, controlled Phase II study to evaluate safety, immunogenicity and dose response of the measles vaccine MVA mBN85B in healthy children aged 6 months to 6 years.
- Trial name
- NCT00891007
- Testing
- MVA-mBN85B, Rouvax
- Where
- South Africa
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Bavarian Nordic
Elderly Women
Telerehabilitation on Physical and Mental Health of the Elderly in the Covid-19 Pandemic Context
Introduction: Due to the COVID-19 pandemic scenario, social distancing has become the main strategy to contain this pandemic, causing negative impacts on the physical and mental health of the elderly population.
- Trial name
- NCT05465811
- Testing
- Program of physical exercises and health education by telerehabilitation
- Where
- Brazil
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Paulista University
Postural Control, Postural Balance
Effects of Sensory Integration Training on Static Standing Balance in Older Adults
Balance impairment is a common problem among adults aged 60 years and older due to age-related decline in the visual, vestibular, and somatosensory systems.
- Conditions
- Postural Control, Postural Balance, Balance Training
- Trial name
- NCT07717034
- Testing
- sensory integration training with conventional balance training, conventional balance training
- Where
- Pakistan
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Foundation University Islamabad
Elderly Subjects
Effects of Brain Stimulation During Nocturnal Sleep on Memory Consolidation in Elderly Healthy Subjects
The beneficial effect of nocturnal sleep on memory consolidation is well-documented in young, healthy subjects. Especially, periods rich in slow-wave sleep (SWS) have shown a memory enhancing effect on hippocampus-dependent…
- Trial name
- NCT01791790
- Testing
- Stimulation
- Where
- Germany
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Frontotemporal Dementia, Dementia
Care of Persons With Dementia in Their Environments (COPE) in Programs of All-Inclusive Care of the Elderly (PACE)
The protocol is organized into three Phases - In Phase I an online training program will be developed in "Care of Persons with Dementia in their Environments" (COPE) -an evidence-based bio-behavioral dementia program -using…
- Conditions
- Frontotemporal Dementia, Dementia, Multi-Infarct Dementia, Vascular Dementia
- Trial name
- NCT04165213
- Testing
- Care of Older Persons in their Environment (COPE) online module training
- Where
- United States
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Healthy
Performance Evaluation and Research for Older Adults Requiring Major Surgery
The purpose is to identify modifiable factors in older adults associated with functional decline following major non-emergent surgery.
- Trial name
- PERFORM (NCT00487890)
- Where
- United States
- Volunteers
- 214 people, healthy volunteers welcome
- Sponsor
- University of Washington
Child Development
PROmoting Early Childhood Outside (PRO-ECO)
Licensed early learning and childcare centres (ELCCs) can provide children with rich opportunities for outdoor play that they may not otherwise experience in their home or community.
- Trial name
- PRO-ECO (NCT05073380)
- Testing
- Intervention Group - PRO-ECO Intervention, Wait List Group - Normal Daily Practice
- Where
- Canada
- Volunteers
- 333 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
COVID-19
Phase I Clinical Trial With New SARS-CoV-2 CoVacHGMix Type 5 Adenoviral Vector Vaccine
The CoVacHGMix adenoviral vector vaccine is a new vaccine developed to protect against SARS-CoV-2 and is a Phase I study designed based on adaptive clinical trial standards.
- Trial name
- NCT05526183
- Testing
- Adeno-viral vector vaccine
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Leadership, Identification
The 5R Shared Leadership Program in Older Adult Walking Groups
To test the efficacy of the 5R Shared Leadership program in older adults on participants' identification with their walking group, group cohesion, walking activity, and well-being, compared to a regular group walking program, the…
- Conditions
- Leadership, Identification, Empowerment
- Trial name
- NCT05038423
- Testing
- 5R Shared Leadership Program, 12-week structured walking program
- Where
- Belgium
- Volunteers
- 503 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Healthy Elderly
Study to Validate a Computerized Neuropsychological Test Battery
This study is comparing a new computer-based method of administering neuropsychological tests to the standard method of verbal and paper/pencil tests administered in person by an examiner.
- Trial name
- NCT01421446
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- LifeBridge Health
Mental Wellbeing of Older Adults
Resilience Toolbox Intervention in Elderly Care
The goal of this cluster randomized controlled trial is to test if the Support4Resilience toolbox can improve mental wellbeing of healthcare workers in elderly care.
- Trial name
- S4R (NCT07504042)
- Testing
- Support4Resilience toolbox
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- University of Stavanger
Respiratory Syncytial Viruses, Lower Respiratory Tract Disease
A Study of an Adenovirus Serotype 26 Pre-fusion Conformation-stabilized F Protein (Ad26. RSV. preF) Based Respiratory Syncytial Virus (RSV) Vaccine in the Prevention of Lower Respiratory Tract Disease in Adults Aged 60 Years and Older
The study will enroll up to 27,200 participants in order to demonstrate the efficacy of the active Ad26.RSV.preF-based study vaccine in the prevention of Reverse Transcription Polymerase Chain Reaction (RT-PCR) confirmed…
- Trial name
- EVERGREEN (NCT04908683)
- Testing
- Adenovirus serotype 26 (Ad26)-based respiratory syncytial virus (RSV). preF
- Where
- 272 sites in United States, Australia and 12 more
- Volunteers
- 25,236 people, healthy volunteers welcome
- Sponsor
- Janssen Vaccines & Prevention B.V.
Cardiac Function and Hemodynamics
Cardiac and Vascular Responses to Creatine Supplementation in Elderly Men
The purpose of this study is to investigate the impact of creatine supplementation alone or in combination with a moderate session of physical activity on vascular reactivity and heart hemodynamics in elderly men.
- Trial name
- NCT05329480
- Testing
- Creatine Monohydrate, Maltodextrin
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Radford University
Sleep Duration, Child Obesity
Effect of Sleep Extension on Body Weight and Learning in Children (More2Sleep)
More2Sleep is a randomized, controlled, parallel trial with two groups (sleep extension vs control) including 142 school-aged children (6-12 years) who have a BMI above average, defined as age- and sex-specific BMI Z-score above…
- Conditions
- Sleep Duration, Child Obesity, Child Development, Child Behavior
- Trial name
- More2Sleep (NCT06341179)
- Testing
- Sleep extension
- Where
- 3 sites in Denmark
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Influenza
Study to Monitor the Safety and Reactogenicity of Fluarix™ in Korean Subjects Aged > 6 Months of Age.
The present study collects data on safety and reactogenicity of the vaccine in the local target population (600 or more subjects) as per the requirement of Korean Food and Drugs Administration (KFDA).
- Trial name
- NCT00750360
- Testing
- FluarixTM
- Volunteers
- 883 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Healthy Volunteers
First-in-human: Single Ascending Dose, Food Effect, Drug-drug Interaction, Multiple Ascending Dose, Proof of Pharmacology
The purpose of this study is to evaluate the safety, tolerability and pharmacokinetics (PK) and pharmacodynamics (PD) of single and multiple ascending oral doses of ASP6282 in healthy male and female subjects.
- Trial name
- NCT02420782
- Testing
- ASP6282, Itraconazole, Pilocarpine
- Where
- 2 sites in Germany, United Kingdom
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Astellas Pharma Europe B.V.
Exercise
Differences in Rate of Recovery Between Young and Middle-aged Men After Downhill Running
The aim of this study is to evaluate differences in rate of recovery between young and middle-aged men after prolonged (downhill) running.
- Trial name
- NCT04025723
- Testing
- Downhill running
- Where
- Israel
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Gepner Yftach
Pneumonia, Bacterial
Trial to Evaluate Safety and Immune Response of an Investigational Pneumococcal Vaccine in Adults Aged 50 To 64 Years
This study will evaluate the safety and immune response of a new formulation of pneumococcal vaccine, PnMAPS30plus, in healthy adults aged 50 to 64 years.
- Trial name
- NCT07428759
- Testing
- Pn-MAPS30plus, PCV20
- Where
- 2 sites in Australia
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
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