Clinical trials: Geriatric Care
Elderly People Institutionalized in Long-term Care Services
Humoral and Cellular Responses to Vaccination Against Coronavirus Disease 2019 (COVID-19) in the Very Elderly Living in Geriatric Institutions
The main objective of this study is to describe the humoral and cellular response to BNT162b2 vaccination in people over age 75 institutionalized in the long-term care units of the Paris Public Hospitals (APHP)
- Trial name
- COGEVAX-BIO (NCT04961502)
- Testing
- Blood test to describe the humoral and cellular response to vaccination BNT162b2 in the elderly
- Where
- France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Gérond'if
Covid19
Geriatric Care for Older People Hospitalised for COVID-19
Current COVID-19 pandemic implies regular treatment adaptation by physician, according to scientific publication evolution. Older adults are particularly affected by COVID-19, with the higher severe form prevalence and the higher…
- Trial name
- COVAGERT (NCT04947943)
- Where
- France
- Volunteers
- 230 people
- Sponsor
- University Hospital, Montpellier
Geriatric Patients
Attitudes and Beliefs Related to Benzodiazepine Deprescribing
The use of benzodiazepines in older adults is associated with an increased risk of adverse effects due to age-related physiological changes.
- Trial name
- BENZ-AC (NCT07474532)
- Testing
- Patient rPATD Benzo questionnaire, Geriatrician rPATD Benzo questionnaire
- Where
- France
- Volunteers
- 96 people
- Sponsor
- Hospices Civils de Lyon
Sepsis
Infected Elders in the Emergency Department: Outcomes and Processes of Care
The purpose of this study is to determine factors which predict a complicated hospital course and then to develop from these findings an Emergency Department guideline to assist in knowing who is at highest risk of elderly…
- Trial name
- NCT00591955
- Where
- United States
- Volunteers
- 213 people
- Sponsor
- Ohio State University
Other Cancer
A Geriatric Oncology Collaborative Care Intervention for Older Adults With Advanced Cancer
The purpose of this research study is to develop a geriatric oncology collaborative care intervention to enhance the quality of life, symptom burden, and functional outcomes of older adults with advanced gastrointestinal (GI) and…
- Trial name
- NCT03721926
- Testing
- Usual Care, Geriatric Oncology Collaborative Care
- Where
- United States
- Volunteers
- 91 people
- Sponsor
- Massachusetts General Hospital
Delivery; Trauma, Pelvic Floor; Perineal Rupture, Obstetric
Perineal Preparation for Pregnant Ladies.
Pregnant participants will be recruited at the obstetrics outpatient clinic during their visits 4 weeks before the due date. They are randomized into two groups. The first group will be educated to do digital perineal massage.
- Conditions
- Delivery; Trauma, Pelvic Floor; Perineal Rupture, Obstetric, Pelvic Floor Muscle Weakness
- Trial name
- NCT03287258
- Testing
- 3 program, one program
- Where
- Egypt
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Kasr El Aini Hospital
Breast Neoplasms, HER2/Neu Positive
Tolerability of the Combination of Lapatinib and Trastuzumab in Adults Age 60 or Older With HER2 Positive Locally Advanced or Metastatic Breast Cancer
This phase II trial studies the side effects and how well lapatinib ditosylate and trastuzumab work in treating older patients with human epidermal growth factor receptor 2 (HER2)-positive breast cancer that has spread from where…
- Conditions
- Breast Neoplasms, HER2/Neu Positive, Geriatric Health Services
- Trial name
- NCT01273610
- Testing
- Lapatinib, Trastuzumab, laboratory biomarker analysis
- Where
- 8 sites in United States
- Volunteers
- 40 people
- Sponsor
- City of Hope Medical Center
Perception
Emerging Physical Therapy Practice in Palliative Care: A Survey of Perceptions of Physical Therapists
The purpose of this study is to explore emerging physical therapy practice in palliative care, and the perceptions of physical therapists regarding their care of the functionally dependent elderly, including: (1) the role and…
- Trial name
- NCT01336361
- Testing
- Survey
- Where
- United States
- Volunteers
- 228 people, healthy volunteers welcome
- Sponsor
- University of Montana
Coronary Artery Disease
Symptom Management Intervention in Elderly Coronary Artery Bypass Patients
The major purpose of this experimental study is to test the effects of the symptom management home care nursing intervention (SMHCNI) on recovery outcomes of elderly CABG patients, using a randomized, two group (n=284) repeated…
- Trial name
- NCT00572988
- Volunteers
- 232 people
- Sponsor
- University of Nebraska
Sarcopenia, Malnutrition
EAMA Sarcopenia in Acute Care Patients in 9+European Countries
This collaborative study in 9 geriatrics units across Europe aims to apply emerging research to clinical practice, following the "Action-Research Philosophy" (11).
- Trial name
- EAMA9+ (NCT04039620)
- Testing
- Observational study, no interventions expected
- Where
- Spain
- Volunteers
- 366 people
- Sponsor
- Parc de Salut Mar
Elderly Cardiac Patients With Multimorbidity and Burnout Among Their Caregivers
Quality of Life of Elderly Patients and Burnout Among Their Care Givers
Older people with multimorbidity are frequent users of health care services, and there is a relationship between the number of chronic conditions and health care costs.
- Trial name
- NCT05475496
- Testing
- Measurements of quality of life and burnout
- Volunteers
- 265 people
- Sponsor
- Sohag University
Elderly People, Living Alone in a Residence With Care Giver
Comparative Study of QuietCare
The objective of the study is to examine the efficacy and safety of QuietCare in a randomized, open study in elderly subjects living in assisted/ independent living facilities for 6 months.
- Trial name
- NCT01839825
- Testing
- QuietCare
- Where
- Japan
- Volunteers
- 202 people, healthy volunteers welcome
- Sponsor
- National Center for Geriatrics and Gerontology, Japan
Primary Health Care
Individualizing Disease Prevention for Middle-Aged Adults
The primary objective of this study is to help patients compare the benefits of various preventive care services, based on their individual risk factors (such as smoking status, obesity, high blood pressure, high cholesterol…
- Trial name
- NCT03023813
- Testing
- Intervention
- Where
- United States
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Glen Taksler
Fractures, Hip, Local Anesthesia
Influence of Peri-operative Anesthetic and Analgesic Care on the Outcome of Patients Undergoing Hip Fracture Surgeries. A Prospective Study
The purpose of this voluntary research study is to clarify whether or not a single injection nerve block done before surgery and after surgery nerve block catheter can effectively enhance recovery in elderly hip fracture patients…
- Conditions
- Fractures, Hip, Local Anesthesia, Geriatric, Nerve Block
- Trial name
- NCT06925789
- Testing
- Ropivacaine
- Sponsor
- Milton S. Hershey Medical Center
Frailty
SOLAR- Frailty Screening and Multidisciplinary Assessment of Older Adults in the Emergency Department
SOLAR is a randomised control trial exploring the role of Comprehensive Geriatric Assessment (CGA) in older adults who screen positive for frailty based on the Identification of Seniors at Risk (ISAR) tool the the Emergency…
- Trial name
- SOLAR (NCT04629690)
- Testing
- SOLAR
- Where
- Ireland
- Volunteers
- 229 people
- Sponsor
- University of Limerick
Cognitive Impairment
Health Care Courses of Elderly Hospitalized Patients for Inappropriate Reasons: Qualitative and Economic Analyzes
For almost 17 % of cases patients over 75 years are sent for inappropriate reasons to the emergency unit. They are described as inappropriate hospitalization because they don't require the use of technical platform or diagnostic…
- Trial name
- PAGE (NCT02749669)
- Testing
- Qualitative research
- Where
- France
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Régis AUBRY
Aged, Nursing Homes
International Normalised Ratio Evaluation by Generalist Practitioners in Full-time Care Establishments for the Elderly
The main objective of this study is to evaluate, for a 6-month observation period, the concordance in terms of clinical decision making concerning therapeutic adjustment as determined by a weekly capillary International…
- Trial name
- INR-Cap pilote (NCT02614573)
- Testing
- CoagucheckXSR Capillary INR measures
- Where
- France
- Volunteers
- 31 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Delirium
Incidence and Prognostic Value of Delirium in Patients With Acute Coronary Syndromes
The Purpose of this study is to evaluate the incidence of delirium in patients with acute coronary syndromes admitted to a Intensive Care Unit Patients.
- Trial name
- NCT02356523
- Testing
- Confusion Assessment Method
- Where
- Italy
- Volunteers
- 700 people
- Sponsor
- Ospedale San Donato
Mortality
Statins In The Elderly
In patients ≥ 75 years, there is no evidence that statins in primary prevention are associated with a decreased mortality and recent US recommendations consider statins in people only between 40 and 75 years.
- Trial name
- SITE (NCT02547883)
- Testing
- Cessation of statin
- Where
- France
- Volunteers
- 1,230 people
- Sponsor
- University Hospital, Bordeaux
Wilson Disease
Efficacy and Safety of ALXN1840 Administered for 48 Weeks Versus Standard of Care in Participants With Wilson Disease
The study will evaluate the efficacy and safety of ALXN1840 (formerly called WTX101) administered for 48 weeks compared to standard of care (SoC) in Wilson Disease (WD) participants aged 12 and older in the Primary Evaluation…
- Trial name
- NCT03403205
- Testing
- ALXN1840, SoC Therapy
- Where
- 56 sites in United States, Australia and 20 more
- Volunteers
- 214 people
- Sponsor
- Alexion Pharmaceuticals, Inc.
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