Clinical trials: Geriatric Care
Depressive Disorder, Treatment-Resistant
A Study of Esketamine Nasal Spray Plus a New Standard-of-care Oral Antidepressant or Placebo Nasal Spray Plus a New Standard-of-care Oral Antidepressant in Adult and Elderly Participants With Treatment-resistant Depression
The purpose of this study is to evaluate the efficacy of treating participants with treatment-resistant depression (TRD) who have failed at least 2 (and no more than 6) prior antidepressant (AD) treatments in the current moderate…
- Trial name
- NCT03852160
- Testing
- Esketamine 28 mg, Esketamine 56 mg, Esketamine 84 mg
- Sponsor
- Janssen-Cilag International NV
Elderly, Pharmaceutical Care
Medication Safety of Elderly Patients in Hospital and Ambulatory Setting
The purpose of this study is to determine whether additional pharmaceutical care for elderly patients (home-cared patients, nursing-home residents) has a positive impact on drug-related readmissions.
- Conditions
- Elderly, Pharmaceutical Care, Hospital Readmission, Health Services for the Aged
- Trial name
- NCT01578525
- Testing
- Pharmaceutical Care Service
- Where
- Germany
- Volunteers
- 61 people
- Sponsor
- RWTH Aachen University
Mobile Applications, Mobile Health
Use of Smartphone Health Applications Among Patients Aged 18 to 69 Years Recruited in Primary Care in Grenoble Area
This study evaluates the frequency of use of smartphone health applications among people consulting in primary care in the Grenoble region, France.
- Trial name
- Smartcheck (NCT03351491)
- Where
- 13 sites in France
- Volunteers
- 597 people, healthy volunteers welcome
- Sponsor
- University Grenoble Alps
Medication Adherence
Improvement of Intentional and Unintentional Non-adherence in the Elderly
The purpose is to study if different factors influence medicine adherence in elderly people. In this study number of generic substitution and use of non-prescription drugs, herbal medicine and dietary supplement is in focus.
- Trial name
- NCT01512238
- Testing
- Pharmaceutical care
- Volunteers
- 630 people
- Sponsor
- University of Aarhus
Dental Plaque, Bleeding of Subgingival Space
Antibacterial Photodynamic Therapy as an Adjunctive Treatment on Oral Hygiene in Elderly Persons
On average, the dental condition of elderly people is poor due to various reasons. The importance of oral health maintenance of the ageing population has been recognized by the World Health Organization (WHO), as oral health…
- Conditions
- Dental Plaque, Bleeding of Subgingival Space, Oral Complication
- Trial name
- NCT06576063
- Testing
- Lumoral Treatment, Standard oral hygiene methods
- Where
- 3 sites in Finland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Koite Health Oy
Frailty, Old Age
Integrating Health Promotion With and for Older People - eHealth
The Integrating Health promotion with and for Older People eHealth (IHOPe) project is expected to contribute vital knowledge on how older peoples capabilities and societal resources can be used in a more efficient way to promote…
- Trial name
- IHOPe (NCT04416815)
- Testing
- Integrating Health promotion with and for Older People - eHealth
- Where
- Sweden
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Göteborg University
Health Literacy
Health Literacy in Geriatric Patients
Health Literacy is one's ability to understand health information well enough to make informed decisions about their health. Limited health literacy makes it hard for people to understand complex health issues and follow health…
- Trial name
- NCT06971393
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- Hamilton Health Sciences Corporation
Osteoporotic Fractures, Osteoporosis, Postmenopausal
Zoledronic Acid for Osteoporotic Fracture Prevention (ZEST II)
The goal of this study is to perform the first fracture reduction clinical trial with a potent antiresorptive agent (intravenous zoledronic acid) in the most vulnerable long-term care population.
- Trial name
- ZEST II (NCT02589600)
- Testing
- Zoledronic acid, vitamin D, calcium
- Where
- United States
- Volunteers
- 310 people
- Sponsor
- Susan L. Greenspan
Atrial Fibrillation (AF)
PRO-AF 52: Monthly Primary-Care 12-Lead ECG Screening for Incident Atrial Fibrillation in Adults Aged ≥65 Years
This prospective, single-arm study will evaluate the feasibility and yield of monthly, in-clinic 12-lead electrocardiogram (ECG) screening performed at affiliated Family Health Centers (Aile Sağlığı Merkezleri; ASMs) in Ordu…
- Trial name
- PRO-AF 52 (NCT07438054)
- Testing
- Monthly 12-lead ECG
- Where
- Turkey (Türkiye)
- Volunteers
- 1,000 people
- Sponsor
- Kotyora Family Medicine Health Management and Education Association
General Surgery
Elder-friendly Approaches to the Surgical Environment (EASE) Study
The aim of this study is to examine the impact implementing an elder-friendly surgical unit has on post-operative complications, mortality and quality of life for patients ≥ 65 years old who have undergone emergency surgical care.
- Trial name
- EASE (NCT02233153)
- Testing
- Elder-Friendly Surgical Unit
- Where
- 2 sites in Canada
- Volunteers
- 723 people
- Sponsor
- University of Alberta
Frailty, Dementia
HEalthy Aging Team Supported Home-care Services (HEAT-YASAM)
Depending on the YASAM project which was established to home-visit evaluate community-dwelling older adults (80 years of age and over), we aimed to determine the prevalence (prevalence) of geriatric syndromes (dependence…
- Conditions
- Frailty, Dementia, Depression, Malnutrition
- Trial name
- HEAT-YASAM (NCT05993572)
- Testing
- Comprehensive Geriatric Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Gulhane Training and Research Hospital
Heart Failure, Telemedicine
Evaluating Telehealth Home Care for Elderly Veterans With Congestive Heart Failure
Congestive heart failure (CHF) is one of the most common reasons for hospitalization in patients aged 65 years and older. Many hospitalizations for CHF are potentially preventable if the warning signs of decompensation are…
- Trial name
- NCT00057200
- Testing
- Telephone, videophone care
- Where
- United States
- Volunteers
- 198 people
- Sponsor
- US Department of Veterans Affairs
Nursing Students, Education Program on Dementia
Enhancing Healthcare Students' Attitudes Toward Dementia Care Through Virtual Reality Education
This quasi-experimental study focuses on Indonesian nursing students and aims to examine the effectiveness of virtual reality (VR) dementia educational programs. The study addresses the following research questions: 1.
- Trial name
- NCT06629844
- Testing
- The VR dementia education group, The control group
- Where
- Indonesia
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Universitas Airlangga
Depression
Tailored Implementation Intervention for Managing Depressed Elderly Patients in Primary Care
Background The prevalence of depression is high and the elderly have an increased risk of developing a chronic course. International data suggest that depression in the elderly is under-recognised, the latency before clinicians…
- Trial name
- TICD (NCT01913236)
- Testing
- Implementation intervention
- Where
- Norway
- Volunteers
- 80 people
- Sponsor
- Sykehuset Innlandet HF
Diabetes
Diabetes in the Elderly: Retrospective Study
Diabetes is highly prevalent in the elderly, afflicting about 20% of older adults aged 65-75 years and 40% of adults >80years of age. Management of hyperglycemia is challenging in the geriatric population in long-term facilities.
- Trial name
- NCT01104168
- Where
- 2 sites in United States
- Volunteers
- 1,409 people, healthy volunteers welcome
- Sponsor
- Emory University
Vitamin C Deficiency, Scurvy
Study of Prevalence and Risk Factors of Hypovitaminosis C in Long Term Care Unit
The clinical finding of skin rashes which appear after a vitamin C deficiency in Long Term Care Unit leads us to believe that the institutional diet could predispose to this kind of deficiency.
- Trial name
- Vitamin C (NCT03807791)
- Testing
- Blood sample
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Hospices Civils de Lyon
Patients Aged 55 or Older, BMI More Than 40 kg/m2
A Real-Time Ultrasound Guided Approach For Spinal Anesthesia
Our goal was to compare the number of attempts to perform spinal anesthesia using real-time ultrasound guidance versus landmark technique in patients meeting predefined criteria for difficult spinal anesthesia.
- Conditions
- Patients Aged 55 or Older, BMI More Than 40 kg/m2, Scoliosis
- Trial name
- NCT01570491
- Testing
- ultrasound-guided spinal anesthesia, standard spinal anesthesia
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- The Cleveland Clinic
Depression
Treatment for Depressed Primary Care Patients
This research study develop a collaborative depression care management model (C-DCM) that encourages collaboration between primary care physicians (PCPs) and trained social workers employed by community-based, public and…
- Trial name
- NCT01014312
- Testing
- Depression Care Management (DCM), Enhanced Care
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Weill Medical College of Cornell University
Frailty in Adult Surgery, Frail Elderly Syndrome
Patient's Database: Prepare for Your Surgery Program
Frailty is a multidimensional syndrome that predominantly affects older people and people with long-term treatments such as cancer and chronic pain.
- Conditions
- Frailty in Adult Surgery, Frail Elderly Syndrome, Database, Perioperative Care
- Trial name
- NCT06857981
- Testing
- Clinical data collection
- Where
- 2 sites in Chile
- Volunteers
- 120 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Acute Pain, Analgesics
Monitoring Side Effects Of Pain Medication Prescribing By Emergency Department In Patients Over 65
Half of the people over the age of 65 are not functioning at their optimal level because of interference from pain. > 50% of older adults had taken prescriptions of pain medication beyond a 6-month period.
- Conditions
- Acute Pain, Analgesics, Elderly
- Trial name
- MOSE65 (NCT02046681)
- Where
- 5 sites in Italy
- Volunteers
- 1,000 people
- Sponsor
- Azienda Ospedaliera S. Maria della Misericordia
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