Clinical trials: Geriatric Care
Delirium
Brief Delirium Assessments in Non-Intensive Care Unit (ICU) Patients
Delirium is an acute confusional state characterized by fluctuating mental status, inattention, and either disorganized thinking or an altered level of consciousness.
- Trial name
- NCT01162369
- Where
- 2 sites in United States
- Sponsor
- Vanderbilt University Medical Center
EMR Reminders to Improve Rates of Recommended Care
Electronic Medical Record Reminders and Panel Management to Improve Primary Care of Elderly Patients
The investigators conducted a controlled trial to assess the effectiveness of electronic medical record (EMR) reminders, with or without a panel manager, on completion of health care proxy, osteoporosis screening, and influenza…
- Trial name
- NCT01313169
- Testing
- EMR Reminder, EMR Reminder + Panel management
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Occupational Therapy
Effects of a Structured Occupational Therapy Intervention in an Acute Geriatric Unit
Objectives: To compare the benefits of structured occupational therapy intervention by a single geriatric therapist with the benefits of the conventional treatment model in the functional recovery of patients admitted to an acute…
- Trial name
- NCT01094002
- Testing
- Occupational therapy intervention
- Where
- Spain
- Volunteers
- 400 people
- Sponsor
- Complejo Hospitalario Universitario de Albacete
HNSCC, Oral Cavity Cancer
Special Care Patterns for Elderly HNSCC Patients Undergoing Radiotherapy
The number of elderly head-and-neck squamous cell carcinoma (HNSCC) patients is increasing; however, the evidence regarding the ideal treatment for this often vulnerable and frail patient cohort is limited.
- Conditions
- HNSCC, Oral Cavity Cancer, Oropharynx Cancer, Hypopharynx Cancer
- Trial name
- SENIOR (NCT05337631)
- Where
- 18 sites in United States, Cyprus and 3 more
- Volunteers
- 1,500 people
- Sponsor
- University Hospital Freiburg
Myeloid Malignancy, Acute Myeloid Leukemia
A Telehealth Advance Care Planning Intervention
The objective of this project is to conduct a pilot randomized trial to assess the preliminary efficacy of a telehealth-delivered Serious Illness Care Program on healthcare communication, patient anxiety and distress, as well as…
- Conditions
- Myeloid Malignancy, Acute Myeloid Leukemia, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative Neoplasm
- Trial name
- SICP RCT (NCT05875805)
- Testing
- Telehealth Serious Illness Care Program, Education Control
- Where
- United States
- Volunteers
- 207 people
- Sponsor
- University of Rochester
Aged, Postoperative Period
Impacts of Low-Dose Dexmedetomidine on Sleep Quality in Mechanically Ventilated ICU Patients
Sleep disturbances frequently occur in intensive care unit (ICU) patients undergoing mechanical ventilation. In a previous study, sedative dose dexmedetomidine (median 0.6 microgram/kg/h) improved sleep quality in mechanically…
- Conditions
- Aged, Postoperative Period, Intensive Care Units, Mechanical Ventilation Complication
- Trial name
- NCT03335527
- Testing
- Dexmedetomidine
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Peking University First Hospital
Sarcopenia, Sensitivity
Performance Indicators of the SARC-F Questionnaire in Acute Care
The study applies the Sluggishness, Assistance in walking, Rising from a chair, Climb stairs, Falls (SARC-F) questionnaire in older patients hospitalized in an acute care geriatric unit and aims to determine its performance…
- Conditions
- Sarcopenia, Sensitivity, Old Age; Debility
- Trial name
- SARC-F-CHUB (NCT04757454)
- Testing
- 5-item SARC-F questionnaire
- Where
- Belgium
- Volunteers
- 105 people
- Sponsor
- Brugmann University Hospital
Diffuse Large B Cell Lymphoma, Follicular Lymphoma Grade 3B
Geriatric-guided Care Versus Conventional Care in Elderly Unfit/Frail Patients With Diffuse Large B-cell Lymphoma in First Line Treatment
The aim of this multicenter, non-randomized, cluster controlled trial study is to evaluate the impact of a geriatric-guided approach with a pro-active rehabilitative/nutritional plan for elderly unfit/frail DLBCL patients…
- Trial name
- NCT07476105
- Testing
- Geriatric-guided supportive care, Conventional supportive care
- Where
- 24 sites in Italy
- Volunteers
- 170 people
- Sponsor
- Fondazione Italiana Linfomi - ETS
Frail Elderly, Medication Errors
MD.2 Medication Dispenser Medication Adherence Study
The objective of this study is to quantify the benefits of using the MD.2 on health outcomes.
- Trial name
- NCT00560001
- Testing
- MD.2 Medication Dispenser
- Where
- United States
- Volunteers
- 600 people
- Sponsor
- Interactive Medical Developments
Common Infectious Diseases
Effect of the Consumption of a Fermented Milk on Common Infections in Children Aged 3-6 Years, Attending Day Care Centers
This multicentric, randomized, double-blind and controlled study aims to examine the effect of a fermented dairy product containing the probiotic Lactobacillus casei DN-114 001 (Actimel® = tested product) on the incidence of…
- Trial name
- NCT01200173
- Testing
- 1-Fermented dairy product containing the probiotic Lactobacillus casei DN-114 001 (Actimel®), 2-Non fermented dairy product (control)
- Where
- Russia
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Danone Global Research & Innovation Center
Elderly Patient (>70 Years), Loss of Mobility
Elderly Patient at Risk of Loss of Mobility, Exercise - Primary Care, Prevention, Care Pathways
Loss of mobility is predictive of a loss of autonomy and is often the first sign of functional decline. Loss of mobility is also associated with poor perceived quality of life, depressive symptoms, high risk of adverse events…
- Trial name
- PRISME-3P (NCT02847871)
- Testing
- PRISME-3P program
- Where
- France
- Volunteers
- 39 people
- Sponsor
- Hospices Civils de Lyon
Leukemia, Myelodysplastic Syndromes
Low-Dose Decitabine Compared With Standard Supportive Care in Treating Older Patients With Myelodysplastic Syndrome
RATIONALE: Decitabine may help myelodysplasia cells develop into normal stem cells. It is not yet known if decitabine is more effective than standard supportive care in treating myelodysplastic syndrome.
- Conditions
- Leukemia, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative Neoplasms
- Trial name
- NCT00043134
- Testing
- decitabine
- Where
- 46 sites in Austria, Belgium and 8 more
- Volunteers
- 220 people
- Sponsor
- European Organisation for Research and Treatment of Cancer - EORTC
Chronic Kidney Disease Stage 5, Chronic Kidney Disease Stage 4B
Prognostic Value of a Multidimensional Assessment for Survival in Elderly Patients With CKD 4B/5
The aim of this study is to determine a multidimensional signature (integrating frailty and patient-reported outcomes measures (PROMs) at entry into stage 4B/5 CKD) to improve prediction of renal death (dialysis, transplantation…
- Trial name
- PROFILER (NCT06825234)
- Where
- 2 sites in France
- Volunteers
- 390 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Depression
Primary Prevention of Major Depression in Later Life
The Institute of Medicine has called for studies of "indicated" preventive interventions to reduce the incidence of mental illness in persons already symptomatic but not yet presenting with fully developed clinical syndromes.
- Trial name
- NCT00326677
- Testing
- Problem Solving Therapy, Dietary Education
- Where
- 2 sites in United States
- Volunteers
- 306 people
- Sponsor
- University of Maryland, College Park
Falls
Establishment of an Integrated Model for Prevention of Elderly Falls
Falls, with a high prevalence, high risk and consequent medical and social costs, are an important issue for medical care and health promotion in the elderly. The prevalence of falls in the elderly lies in between 10-20%.
- Trial name
- NCT00804492
- Testing
- Multifaceted intervention
- Where
- Taiwan
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Sarcopenia
Combined Exercise and Nutrition Intervention for Possible Sarcopenia Among Older Adults in Primary Care
The purpose of this study is to assess the impact of a combined exercise-nutrition intervention in primary clinics on sarcopenia indices, physical function, and quality of life in community-dwelling older adults with possible…
- Trial name
- NCT06049914
- Testing
- Experimental group
- Where
- 3 sites in South Korea
- Volunteers
- 94 people
- Sponsor
- Kyunghee University Medical Center
Acute Myeloid Leukemia (AML)
Improving Delivery of Aging-Related Supportive Care for Older Adults With Acute Myeloid Leukemia
The goal of this clinical trial is to test a way of delivering supportive care to adults 60 years and older who are starting venetoclax-based treatment for newly diagnosed acute myeloid leukemia (AML).
- Trial name
- ACTIVE DEFAULT (NCT07777471)
- Testing
- Active Default
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Depression, Anxiety, Age Problem
Analysis of Anxiety and Depression Among Elderly People
This study is a single-center, cross-sectional, and survey study. Through questionnaire surveys, information about the anxiety and depression status of residents of elderly care institutions in Zhejiang Province is collected.
- Trial name
- NCT06006234
- Testing
- questionnaire survey
- Where
- China
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Malnutrition in the Elderly
Impact of the Time of Oral Nutritional Supplements (ONS) Consumption on Daily Alimentary Intakes of Malnourished Elderly
Malnutrition is a severe comorbidity in hospitalised patients, especially in elderly. The consumption of Oral Nutritional Supplements (NOS) is one of several tools for fighting against malnutrition.
- Trial name
- ACTICLAN (NCT01261663)
- Testing
- oral nutritional energy and protein enriched supplement (NOS)
- Where
- France
- Volunteers
- 48 people
- Sponsor
- University Hospital, Limoges
Dependency
Comprehensive Geriatric Assessment for Frail Older People
The study "Comprehensive Geriatric Assessment for frail older people in Swedish acute care settings - a randomized controlled study" comprised two study arms: one intervention and one control group.
- Trial name
- NCT02773914
- Testing
- Comprehensive Geriatric Assessment
- Where
- Sweden
- Volunteers
- 155 people
- Sponsor
- Göteborg University
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