Clinical trials: Geriatric Depression
Primary Insomnia, Depression
Paroxetine in the Treatment of Chronic Primary Insomnia
The goal of the study is to examine the role of paroxetine, an antidepressant medication, in the acute and continuation treatment of insomnia.
- Trial name
- NCT00178048
- Testing
- paroxetine
- Where
- 2 sites in United States
- Volunteers
- 66 people
- Sponsor
- University of Pittsburgh
Sleep Quality
Effects of Binaural Beat Music on Elderly Sleep
Background: Older people in long-term care institutions often have poor sleep quality and depression, which may negatively affect their health and welfare. Binaural beat music (BBM) has been proposed as a possible intervention.
- Trial name
- NCT05975853
- Testing
- Binaural beat music group (BBM group), Control group
- Where
- Taiwan
- Volunteers
- 64 people
- Sponsor
- National Cheng Kung University
Geriatric Assessment, Geriatric Oncology
Geriatric Oncology Care in Brazil: Remote Geriatric Assessment-Driven Interventions With Supportive Care
The goal of this clinical trial is to determine whether a telehealth-delivered, geriatric assessment-guided supportive care program (GAIN-S) can improve health outcomes in older adults (age 65 and above) with solid tumors who are…
- Conditions
- Geriatric Assessment, Geriatric Oncology, Quality of Life, Functional Decline
- Trial name
- GAIN-S (NCT07084454)
- Testing
- GAIN-S Multidisciplinary Telehealth Intervention, Standard Oncology Care
- Where
- Brazil
- Volunteers
- 350 people
- Sponsor
- Cristiane Decat Bergerot, PhD
Bipolar Depression
CoQ10 in Geriatric Bipolar Depression
We propose to study and compare measures of brain energy metabolism in geriatric bipolar individuals and healthy older adults. We would also like to investigate changes in brain energy metabolites and in vivo creatine kinase (CK)…
- Trial name
- CoQ10 (NCT00720369)
- Testing
- CoEnzyme Q10
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Mclean Hospital
Depression
Multimodal Identification of Depressive Symptoms in the Elderly
Screening with depression scales alone is subjective, and relying on single-modal data often leads to incomplete identification of symptoms that are easily missed or misdiagnosed.
- Trial name
- multimodal (NCT07112118)
- Testing
- data collection
- Where
- China
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Wuhan Mental Health Centre
Healthy, Perimenopausal Depression
Multidimensional Determinants of Functional Health In Women Aged 45-60
The goal of this observational study is to learn about the multidimensional determinants of functional health in women aged 45 to 60 years.
- Conditions
- Healthy, Perimenopausal Depression, Menopausal Complaints, Bone Mineral Density
- Trial name
- NCT07667699
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Kartal City Hospital
Depression, Anxiety
PHYSICAL ACTIVITY AS A MEASURE OF IMPROVING THE EMOTIONAL STATE AND SOCIALIZATION IN THE ELDERLY
Background: Social isolation, loneliness and anxiety-depressive states are emerging health conditions in the elderly of our society. This situation is related to higher morbidity and mortality.
- Conditions
- Depression, Anxiety, Social Isolation
- Trial name
- NCT04072185
- Testing
- Physical activity
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Child Care
Providing Grandchild Care in Later Life
Grandchild care is a modern global phenomenon arising from increased life expectancy , and, correlated with the rest of the world, the Turkish Statistical Institute's report on aging states that the prevalence of grandchild…
- Trial name
- NCT07501260
- Testing
- Providing grandchild care in old age reduces frailty, depression, and self-care neglect in geriatric outpatients.in Geriatric Outpatients"
- Where
- Turkey (Türkiye)
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- Mersin University
Dysthymic Disorder
Testosterone Replacement in Middle-Aged Hypogonadal Men With Dysthymia: Parallel Group, Double Blind Randomized Trial
Growing evidence supports the notion that Late-onset Dysthymic disorder in middle aged men may be associated with age-related HPG hypofunctioning.
- Trial name
- NCT00260390
- Testing
- Testoviron
- Where
- Israel
- Sponsor
- Sheba Medical Center
Frailty, Osteoporosis
An Interventional Study of Geriatric Frailty, Osteoporosis, and Depression
Frailty, osteoporosis, and depression are three highly prevalent geriatric syndromes. Having these conditions are associated with adverse outcome in physical health, mental health, quality of life, and daily functioning.
- Conditions
- Frailty, Osteoporosis, Depression
- Trial name
- NCT00718432
- Testing
- Exercise and nutritional integrated care, Usual care with education, Problem solving therapy (PST) integrated care
- Where
- Taiwan
- Volunteers
- 406 people
- Sponsor
- National Health Research Institutes, Taiwan
Cognition, Anxiety
Biopsychosocial Effects of Gardening Activities
Due to the increasing number of elderly population worldwide, elderly care is becoming increasingly important and the number of elderly in institutional care is increasing.
- Conditions
- Cognition, Anxiety, Depression, Life Satisfaction
- Trial name
- NCT06844084
- Testing
- Gardening Activity
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Ordu University
Treatment Resistant Depressive Disorder
Ketamine for Treatment Resistant Late-Life Depression
The purpose of this study is to examine the effectiveness of a single infusion of ketamine (KET), to determine which dose is optimal 7 days after infusion using Bayesian Adaptive Randomization, and to learn about how ketamine…
- Trial name
- NCT02556606
- Testing
- Ketamine, Midazolam
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- VA Office of Research and Development
Depression
Evaluating a Behavioral Activities Treatment Program for Depressed Nursing Home Residents
This study will evaluate whether a behavioral activities treatment program improves symptoms of depression in nursing home residents.
- Trial name
- BE-ACTIV (NCT00536406)
- Testing
- BE-ACTIV, Treatment as usual (TAU)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Louisville
Sleep Insufficiency
A Personalized Mind-Body Intervention (MBI) for Improving Sleep Among Women Working in Healthcare
The goal of this pilot study is to determine if a personalized trial testing a Mind-Body Intervention (MBI) can produce a meaningful increase in the average daily sleep duration among women 40-60 years of age working in…
- Trial name
- NCT05789212
- Testing
- Personalized Trial ABCCBA, Personalized Trial CBAABC
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Exercise, Gait
Rhythmically Entrained Exercise in Community-Dwelling Older Adults
Researchers at the University of North Carolina at Greensboro conduct a single-arm intervention trial to investigate the efficacy of a music-based group exercise program for community-dwelling older adults.
- Conditions
- Exercise, Gait, Cognitive Decline, Caregiver Burden
- Trial name
- REECO (NCT05462977)
- Testing
- Group exercise program
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Greensboro
Depression
Incomplete Response in Late Life Depression: Getting to Remission (IRL GREY)
The primary aims of this study are to: 1. Assess the efficacy of aripiprazole augmentation for the acute and continuation treatment of TRLLD.
- Trial name
- IRL GREY (NCT00892047)
- Testing
- venlafaxine XR plus aripiprazole
- Where
- 3 sites in United States, Canada
- Volunteers
- 468 people
- Sponsor
- University of Pittsburgh
Predictive Model
Development and Validation of a Prediction Model for Depression and Anxiety in Perioperative Elderly Adults
Anxiety and depression in later life are highly prevalent, often appear as comorbid disorders, and have many adverse consequences for both the individual and society.
- Trial name
- NCT05600504
- Testing
- no intervention
- Where
- China
- Volunteers
- 6,386 people
- Sponsor
- Chinese PLA General Hospital
Depression
Binaural Beat Music Combined With Rhythmic Photic Stimulation on Depression
Background: Previous studies have suggested that non-pharmacological treatments, such as binaural beat music (BBM) and rhythmic photic stimulation (RPS), may help improve depressive symptoms and enhance quality of life.
- Trial name
- NCT06540157
- Testing
- Binaural Beat Music (BBM) Combined with Rhythmic Photic Stimulation (RPS)
- Where
- Taiwan
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- National Cheng Kung University
Major Depressive Disorder
Vilazodone for Treatment of Geriatric Depression
The purpose of this study is to examine the effects of vilazodone for the treatment of depression in older adults.
- Trial name
- NCT01608295
- Testing
- Vilazodone; Viibryd, Paroxetine; Paxil
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- University of California, Los Angeles
Depression in Old Age
Assessment of Depression (iCGI) in Older People, According to Their Presentation in a Wheelchair or an Ordinary Chair.
This study aims to test for a " wheelchair effect ", as a potential impact of stigma, during the evaluation of clinical global impression of depression.Elderly patients will be asked to sit in a wheelchair, or in a regular chair…
- Trial name
- WHEELDEP (NCT04979299)
- Testing
- Wheelchair
- Where
- 2 sites in France
- Volunteers
- 100 people
- Sponsor
- Hospital Center Guillaume Régnier