Clinical trials: Geriatric Disorder
Human Papilloma Virus Infection Type 16, Human Papilloma Virus Infection Type 18
A Phase III Study of Human Papillomavirus (HPV)-16/18 Vaccine.
A Phase III Double Blinded, Randomized Controlled Study to Evaluate Efficacy of Protection Against HPV-16 and 18 Related Diseases, Immunogenicity and Safety of Recombinant Human Papillomavirus Virus-like Particle Vaccine (Type 16…
- Conditions
- Human Papilloma Virus Infection Type 16, Human Papilloma Virus Infection Type 18, Cervical Intraepithelial Neoplasia
- Trial name
- NCT02733068
- Testing
- HPV-16/18 vaccine
- Volunteers
- 12,000 people, healthy volunteers welcome
- Sponsor
- Shanghai Zerun Biotechnology Co.,Ltd
Healthy, Influenza
Safety of Lactobacillus Rhamnosus GG Versus Placebo in Elderly Subjects Receiving Live Attenuated Influenza Vaccine
This is a Phase I, randomized controlled trial to evaluate the safety of Lactobacillus rhamnosus GG (LGG) versus placebo in elderly subjects receiving the live attenuated influenza vaccine.
- Trial name
- LAIV (NCT01545349)
- Testing
- Lactobacillus rhamnosus GG ATCC 53103 (LGG), Live attenuated influenza vaccine
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Patricia L. Hibberd
Measles, Rubella
Non-interference Study of MR and Yellow Fever Vaccines Among Bangladeshi Infants Aged 9-12 Months
This study will be conducted among 1530 healthy infants of 9 to 12 months of age residing in the Dakshinkhan and Uttarkhan area which is located in Dhaka North City Corporation (DNCC) to enroll the required number of…
- Conditions
- Measles, Rubella, Yellow Fever
- Trial name
- NCT06815835
- Testing
- Measles-Rubella vaccine (Live) I.P. (Freeze Dried) of M/s. Zydus Lifesciences Ltd, Yellow fever Vaccine (WHO prequalified)
- Where
- Bangladesh
- Volunteers
- 1,530 people, healthy volunteers welcome
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Osteopenia
Effects of High-Intensity Interval Training on Bone Health in Hong Kong Older Women
Osteoporosis is an age-related disease, characterized by a decreased bone mass and an increased risk of fragility fractures. Osteoporosis leads to increasing mortality, disabilities, morbidity of chronic pain, and the cost of…
- Trial name
- NCT06888544
- Testing
- HIIT program for 24 weeks with a frequency of 2 times per week., Non-exercise control
- Where
- China
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Hong Kong Baptist University
Sarcopenia in Elderly
Feasibility of Egg White Pudding Supplementation for Individuals in Personal Care Home Centres Needing Dietary Supplementation
This trial is an open-label randomized controlled parallel arm feasibility trial. 54 residents in care homes receiving nutrition supplementation (minimum 40% of each sex, ≥ 50 years of age).
- Trial name
- NCT07805993
- Testing
- Egg White Pudding, Nestle Resource
- Where
- Canada
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Seven Oaks Hospital Chronic Disease Innovation Centre
Mild Cognitive Impairment (MCI), Dementia
Exploring the Impact of Dementia Prevention Programs Using Robots as Intervention Tools on Community Elderly
The purpose of this study is to intervene in the cognitive functions of the community elderly through the "Robot Dementia Prevention Course" training.
- Conditions
- Mild Cognitive Impairment (MCI), Dementia, Cognitive Decline, Psychological Well-being
- Trial name
- NCT06984458
- Testing
- Robot Dementia Prevention Course
- Where
- Taiwan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- National Taiwan Normal University
Active Aging Individuals Aged 65 and Over, Aging
Italian Validation of the dNA Scale and Its Correlation With Neurocognitive Variables
The goal of this experimental multicentric intervention study is to validate, in Italian, the dynamic Neurocognitive Adaptation (dNA) Scale, which has already been validated in English, among a healthy elderly population (aged 65…
- Conditions
- Active Aging Individuals Aged 65 and Over, Aging, Mild Cognitive Impairment (MCI), Dementia
- Trial name
- NCT07533084
- Where
- 8 sites in Italy
- Volunteers
- 265 people, healthy volunteers welcome
- Sponsor
- Neuromed IRCCS
Autism Spectrum Disorder
Pilot Evaluation of a New Computerized Test for Pragmatic Inferences in Children with ASD
This study aims to evaluate the relevance of a new computerized test for pragmatic inferences (TIPi) in children aged 8 to 12 YO, presenting a typical development, autism spectrum disorders, another neurodevelopmental condition…
- Trial name
- TIPI (NCT04245306)
- Testing
- computerized test for pragmatic inferences
- Where
- France
- Volunteers
- 232 people, healthy volunteers welcome
- Sponsor
- Hôpital le Vinatier
Alzheimer's Disease
Study to Assess the Safety, Tolerability and Pharmacokinetics of Single Ascending Oral Doses of J147
This Phase I clinical study is a randomized, double-blind, placebo-controlled, parallel-design study to thoroughly assess the safety profile and PK properties of J147 in healthy subjects.
- Trial name
- NCT03838185
- Testing
- J147
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Abrexa Pharmaceuticals, Inc.
Human Influenza
Safety and Immunogenicity of a Trivalent Influenza Vaccine When Administered to Elderly Subjects
To evaluate the safety of a single intramuscular (IM) injection of trivalent adjuvanted influenza study vaccine, formulation 2012/2013, in elderly subjects and the antibody response to each influenza vaccine antigen, as measured…
- Trial name
- NCT01651104
- Testing
- Adjuvanted Trivalent Influenza Virus Vaccine (aTIV)
- Where
- Belgium
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Novartis Vaccines
Alzheimer's Disease
Group Therapy for Caregivers of Alzheimer's Disease Patients in Spanish Elderly Persons Centres
An experimental study designed to test the effectiveness of a psychological intervention based on group therapy for the caregivers of Alzheimer's disease patients.
- Trial name
- cuiDem (NCT02418806)
- Testing
- Psychotherapy groups, Self-help groups
- Where
- 11 sites in Spain
- Volunteers
- 231 people, healthy volunteers welcome
- Sponsor
- Barcelonabeta Brain Research Center, Pasqual Maragall Foundation
Elderly, Hypertension
Unsupervised Physical Activity in Elderly
To evaluate safety and the effects of a unsupervised physical activity program (USPAP) over blood pressure (BP), physical fitness (PF) and quality of life (QL) of elderly hypertensive patients.
- Conditions
- Elderly, Hypertension, Physical Conditioning
- Trial name
- NCT02976506
- Testing
- Unsupervised exercise program, Physical fitness and quality of life
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Goias
Fall, Aging
Study of Static and Dynamic Posturographic Elements Predictive of Falls in the Institutionalized Elderly
A fall in the elderly is defined by the WHO as "an event in which a person [over 65 years of age] inadvertently falls to a lower level on the ground or other surface than they were previously at".
- Conditions
- Fall, Aging, Gait, Unsteady, Motor Activity
- Trial name
- POSTADYCHUTE (NCT05171036)
- Testing
- Adapted Physical Activity
- Volunteers
- 348 people, healthy volunteers welcome
- Sponsor
- Centre Borelli UMR 9010
Acute Myeloid Leukemia (AML)
Improving Delivery of Aging-Related Supportive Care for Older Adults With Acute Myeloid Leukemia
The goal of this clinical trial is to test a way of delivering supportive care to adults 60 years and older who are starting venetoclax-based treatment for newly diagnosed acute myeloid leukemia (AML).
- Trial name
- ACTIVE DEFAULT (NCT07777471)
- Testing
- Active Default
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Osteoporosis, Accidental Falls
Geriatric Health Exam Osteoporosis Screening
BACKGROUND: The World Health Organization Fracture Risk Assessment Tool (WHO FRAX®) Taiwanese calculator is freely available on line to help osteoporosis management.
- Conditions
- Osteoporosis, Accidental Falls, Fracture
- Trial name
- NCT01934387
- Where
- Taiwan
- Volunteers
- 1,319 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Myocardial Infarction, Acute Coronary Syndrome
Aspirin Dose Comparison in Elderly PCI Patients: 30mg vs. 75mg in Acute Coronary Syndrome
Elderly patients undergoing percutaneous coronary intervention (PCI) face a high risk of both ischemic and hemorrhagic complications necessitating antiplatelet therapy.
- Trial name
- LowASA-PCI (NCT06254391)
- Testing
- Low-dose aspirin
- Where
- Poland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Medical University of Warsaw
Influenza
This Study Was Conducted to Evaluate the Safety and Immunogenicity of IVACFLU-S Produced in Children From 6 Months to Under 18 Years Old and the Elderly Over 60 Years Old in Vietnam
This was an extensive, double-blind, randomized, placebo-controlled phase 3 study that aimed to evaluate the safety and immunogenicity of the seasonal inactivated, split virion, trivalent influenza vaccine (IVACFLU-S) in children…
- Trial name
- NCT04695717
- Testing
- IVACFLU-S
- Where
- 2 sites in Vietnam
- Volunteers
- 864 people, healthy volunteers welcome
- Sponsor
- Vietnam Military Medical University
Gastroparesis, Hip Fracture
Gastric Emptying in Elderly With Hip Fracture
The gastric emptying of 400 ml 12.6% carbohydrate rich drink is investigated in elderly women, age 75-100, with acute hip fracture.
- Conditions
- Gastroparesis, Hip Fracture, Mild Insufficient Nutrition
- Trial name
- GASEMPHIP (NCT02753010)
- Testing
- Gastric emptying of carbohydrate-rich beverage
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Obesity, Overweight
Dietary Effects on Weight Loss and Lipid Profile in Sedentary Women
Negative-calorie diet is among the popular dieting guides for weight loss; however, there is still little knowledge about this method.
- Conditions
- Obesity, Overweight, Life Style
- Trial name
- NCT03066882
- Testing
- NCD, LCD
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- P.L.Shupik National Medical Academy of Post-Graduate Education
Postoperative Complications, Elderly
Elderly Patients Undergoing Surgery During Perioperative Period
The elderly patients have poorer overall conditions and have lower tolerance to trauma, anesthesia, and surgery. Therefore, the incidence of postoperative complications is relatively higher.
- Conditions
- Postoperative Complications, Elderly, Postoperative Delirium (POD), Risk Prediction Model
- Trial name
- NCT07314762
- Where
- China
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.