Clinical trials: Geriatric Disorder
Child, Only
Kaleidoscope Virtual Reality Glasses Pain and Anxiety Levels in Venous Blood Collection Children
The aim of our research is to investigate the effects of distracting children's attention with a kaleidoscope and virtual reality glasses during venous blood collection on perceived pain and anxiety levels.
- Trial name
- NCT06576141
- Testing
- Kaleidoscope, Virtual Reality, control
- Where
- Turkey (Türkiye)
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Erzincan Binali Yildirim Universitesi
Infections, Rotavirus
Safety Study of GSK Biologicals' Rotavirus Vaccine (Rotarix®) Administered to Children Aged <1 Year in the United States
This observational cohort study, conducted through two existing large administrative health databases in the US (outside the Vaccine Safety Datalink) is planned to confirm the safety profile regarding lack of any association of…
- Trial name
- NCT00875641
- Testing
- Health Insurance Database
- Where
- United States
- Volunteers
- 390,659 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Influenza
Immunogenicity and Safety of a Quadrivalent Influenza Vaccine Given by Intramuscular Route in Subjects Aged 18 to 60 Years
The aim of the trial is to evaluate immunogenicity and safety of the quadrivalent influenza vaccine (QIV) and the trivalent influenza vaccine (TIV) (split-virion inactivated) Northern Hemisphere (NH) 2015 2016 seasonal…
- Trial name
- NCT02550197
- Testing
- Quadrivalent influenza vaccine (QIV) (split virion, inactivated) Northern Hemisphere (NH) 2015-2016, Trivalent influenza vaccine (TIV) (split virion, inactivated) NH 2015-2016 formulation
- Where
- 5 sites in South Korea
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Sanofi Pasteur, a Sanofi Company
Pneumonia, Respiratory Tract Diseases
Phase Ⅰa Clinical Trial of a Pneumococcal Vaccine
Infections with Streptococcus pneumoniae often cause serious health problems, especially for infants and the elderly.Failure to cover all polysaccharide types is an even greater problem with adults than with children.
- Conditions
- Pneumonia, Respiratory Tract Diseases, Respiratory Tract Infections
- Trial name
- PⅠCTPV (NCT04087460)
- Testing
- Protein based pneumococcal vaccine(Low dose), Protein based pneumococcal vaccine(Middle dose), Protein based pneumococcal vaccine(High dose)
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- CanSino Biologics Inc.
Social Isolation, Loneliness
COVID-19 and Social Isolation and Loneliness Trial
Social isolation and loneliness worsen older peoples' quality of life, risk of dementia, and contributes to 45,000 deaths/year in Canada - as much as smoking.
- Conditions
- Social Isolation, Loneliness, Geriatric
- Trial name
- SIL (NCT05228782)
- Testing
- HOW R U? Intervention
- Where
- Canada
- Volunteers
- 141 people, healthy volunteers welcome
- Sponsor
- Mount Sinai Hospital, Canada
Obesity, Childhood, Malnutrition
Physical Activity and the Home Environment in Preschool-aged Children in Urban Bangladesh
The overall goal of this study is to generate new knowledge regarding the nutritional and environmental determinants of physical activity in young children living in a densely populated urban community in Bangladesh.
- Conditions
- Obesity, Childhood, Malnutrition, Anemia
- Trial name
- NCT04628897
- Testing
- Exposures
- Where
- Canada
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- The Hospital for Sick Children
HPV Infections
V501 Efficacy Study in Women Aged 18 to 26 (V501-027)
A study to evaluate the efficacy, immunogenicity, safety and tolerability of V501 in adult women
- Trial name
- NCT00378560
- Testing
- Quadrivalent Human Papillomavirus (Types 6, 11, 16, 18) Recombinant Vaccine
- Volunteers
- 1,021 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Heart Failure
Age Gender Left Ventricular Mass and Cardiac Troponin T
The purpose of this study is to determine the influence of functional or anatomic cardiac parameters, age and gender on high sensitivity cTnT (TnThs) levels in healthy individuals.
- Trial name
- NCT01100710
- Where
- Germany
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Heidelberg University
Hypertension
Post-Exercise Hypotension in Elderly Hypertensive Men
The purpose of this study is to compare the effects of two exercise protocols on post-exercise blood pressure versus a control group in elderly hypertensive men.
- Trial name
- HPE (NCT02415582)
- Testing
- Aerobic exercise, Combined exercises, Control
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Hospital de Clinicas de Porto Alegre
Hyperthermia, Heat Stress
Efficacy of Ceiling Fans for Mitigating Thermal Strain During Bed Rest in Older Adults During Heat Waves
With the increasing regularity and intensity of hot weather and heat waves, there is an urgent need to develop heat-alleviation strategies able to provide targeted protection for heat-vulnerable older adults.
- Conditions
- Hyperthermia, Heat Stress, Cooling, Aging
- Trial name
- NCT06142890
- Testing
- No cooling (control), Cooling with ceiling fan
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Ottawa
Geriatric Disorder
Contribution of Actigraphy for the Evaluation of Elbow Range of Motion in the Joint Assessment in Gerontology
In this study, the investigators will measure range of motion of the elbow in a geriatric assessment in 85 subjects aged 65 years or over. These measures will be made by an actigraph and the software analysis BioVal.
- Trial name
- BIOVAL (NCT01462760)
- Testing
- Assessment with inclinometer, Assessment with actigraph
- Where
- France
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nice
Influenza
Safety and Immunogenicity of a Monovalent Inactivated Influenza H3N2 Variant (H3N2v) Vaccine in Adult and Elderly Populations
This is a Phase II open-label study in approximately 200, and up to 240, healthy males and non-pregnant females, aged 18 years and older.
- Trial name
- NCT01746082
- Testing
- Influenza A/H3N2 variant Vaccine
- Where
- 4 sites in United States
- Volunteers
- 211 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Metabolic Syndrome, Menopause
Effects of L-citrulline Supplementation on Vascular Function in Metabolic Syndrome
The objective of this project is to provide evidence that L-Citrulline (CIT) supplementation can improve vascular function in the fasted and acute hyperglycemia conditions in middle-aged and older women with metabolic syndrome.
- Trial name
- NCT06025357
- Testing
- L-Citrulline supplementation
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Texas Tech University
Child Behavior Disorders, Parenting
RCT of Brief Universal Parenting Program to Prevent Child Behavioural and Emotional Difficulties in Greece
This study investigates the impact of a Triple P Seminar Series on positive parenting for universal prevention of behavioural and emotional difficulties in a general Greek sample of parents with children aged 2 to 12.
- Trial name
- NCT02030730
- Testing
- Triple P Seminar Series
- Where
- United Kingdom
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Traumatic Brain Injury
Blended Reality Immersion for Geriatric Head Trauma: The BRIGHT Study
Traumatic brain injury (TBI) is a major public health concern, particularly among older adults (OAs) ≥ 65 years of age. Each year in the United States, TBI results in over 600,000 emergency department visits and hospitalizations…
- Trial name
- BRIGHT (NCT06074328)
- Testing
- Virtual Reality Neurocognitive Exercises administered through an Oculus Headset
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Ebola Virus Disease
A Study of 2-dose Vaccination Regimen of Ad26.ZEBOV and MVA-BN-Filo in Infants
The purpose of this study is to assess the safety and reactogenicity of a heterologous 2-dose regimen utilizing Ad26.ZEBOV (first vaccination; Dose 1) and MVA-BN-Filo (second vaccination; Dose 2) administered intramuscularly (IM)…
- Trial name
- NCT03929757
- Testing
- Ad26.ZEBOV, MVA-BN-Filo, MenACWY
- Where
- 2 sites in Guinea, Sierra Leone
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Janssen Vaccines & Prevention B.V.
Cardiovascular Diseases in Old Age
Reducing PM-associated CV Health Effects for Seniors
The objective of this study is to investigate the effectiveness of air filtration at reducing personal-level exposures to fine particulate matter (PM2.5) and mitigating related cardiovascular (CV) health effects among older…
- Trial name
- NCT03334565
- Testing
- Low efficiency air filtration systems, High efficiency air filtration systems
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Michigan State University
Influenza
Immuno & Reacto of TF Trivalent Influenza Split Vaccine 2003/04 or of Std Formulation Influsplit SSW®/Fluarix™ 2003/04
The aim of the present study is to assess the reactogenicity and immunogenicity of a thiomersal-free influenza vaccine. For comparison, a group of subjects is administered the standard formulation of Influsplit SSW® 2003/2004.
- Trial name
- NCT00731393
- Testing
- Thiomersal free trivalent influenza split vaccine 2003/2004, GlaxoSmithKline Biologicals' Influsplit SSW®/Fluarix™ 2003/2004
- Where
- 13 sites in Germany
- Volunteers
- 157 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
General Population, TDAH
Children and Parents With ADHD and Related Disorders
Almost all rating scales for Attention-Deficit/Hyperactivity Disorder (ADHD) are not validated in France. This clearly hampers the development of the diagnosis and the monitoring of patients but also research in this domain.
- Conditions
- General Population, TDAH, Children Aged 5 to 18 Years
- Trial name
- ChiP-ARD (NCT01260792)
- Testing
- questionnaire
- Where
- France
- Volunteers
- 2,600 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nice
Cardiovascular Disease, Chronic Kidney Disease
Effect of ACE-inhibitors on Aortic Stiffness in Elderly Patients With Chronic Kidney Disease
The goal of this proposal is to investigate the potential for ACE-inhibitors (ACE-I)(drugs primarily used to treat hypertension or congestive heart failure) to prevent or delay cardiovascular disease (CVD) in older adults with…
- Trial name
- NCT00874432
- Testing
- angiotensin converting enzyme inhibitor, lisinopril
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
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