Clinical trials: Geriatric Disorder
Streptococcus Pneumoniae Vaccines
Study to Evaluate the Response Rate to the Licensed Pneumovax 23™ in Elderly Population.
Streptococcus pneumoniae are bacteria which normally live in the upper respiratory tract of humans. However, these bacteria can also cause severe infectious diseases such as pneumonia, septicemia and meningitis.
- Trial name
- NCT00307008
- Testing
- Pneumovax 23™
- Where
- 5 sites in Sweden
- Volunteers
- 1,198 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Influenza Disease
Safety and Immunogenicity of Surface Antigen, Inactivated, Influenza Vaccine Using the Strain Composition 2009/2010 Recommended in Northern Hemisphere in Non-elderly Adult and in Elderly Subjects
Annual trial for registration influenza vaccine with the strain composition for season 2009/2010.
- Trial name
- NCT00918268
- Testing
- Influenza vaccine
- Where
- 3 sites in Italy
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Novartis Vaccines
Obesity
Effects of Grapefruit or Grapefruit Juice on Anthropometry, Dietary Intakes, Appetite, and Metabolic Profile in Overweight and Obese Young and Middle-Aged Adults
This trial examines the effects of grapefruit or grapefruit juice on anthropometry, dietary intakes, appetite, and metabolic profile in overweight and obese young and middle-aged adults.
- Trial name
- GJW (NCT00581074)
- Testing
- diet (grapefruit or grapefruit juice)
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University
Influenza
Study to Demonstrate the Lot-to-lot Consistency and to Evaluate the Safety of an Adjuvanted Influenza Vaccine Candidate
The purpose of this phase IIb study is to demonstrate the consistency of three lots of an adjuvanted influenza vaccine candidate and to evaluate the safety of this vaccine compared to Fluarix™ administered intramuscularly in…
- Trial name
- NCT00321763
- Testing
- Candidate Influenza Vaccine GSK1247446A - 3 different formulations, Fluarix TM
- Where
- 46 sites in Estonia, France and 5 more
- Volunteers
- 3,124 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Frail Elderly
Effect of Hot Water Foot Bath on Daily Living Activities, Insomnia and Fatigue Levels in Frail Geriatric Individuals
Aim: A randomized controlled experimental study was conducted to determine the effect of hot water foot bath on daily living activities, sleep and fatigue levels in frail geriatric individuals.
- Trial name
- NCT07048015
- Testing
- Hot Water Foot Bath
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Eskisehir Osmangazi University
Influenza
A Study to Determine the Immunogenicity and Safety Profile of CSL Limited's Influenza Virus Vaccine Compared to a US Licensed Comparator Influenza Virus Vaccine in a Pediatric Population
The purpose of this study is to determine the immunogenicity and safety profile of CSL Limited's Influenza Virus Vaccine compared to a US licensed comparator Influenza Virus Vaccine in a pediatric population aged greater than or…
- Trial name
- NCT00959049
- Testing
- CSL's Influenza Virus Vaccine (Afluria), Influenza Virus Vaccine (Fluzone)
- Where
- 23 sites in United States
- Volunteers
- 1,474 people, healthy volunteers welcome
- Sponsor
- Seqirus
HPV Infection, HPV Vaccine
Two Domestic HPV Vaccines and Imported HPV Vaccines in Women Aged 13-14 Years Study on Immunogenicity
This is a multi-center, open, prospective cohort study that aims to investigate the immunogenicity and immune persistence of two different domestically produced bivalent HPV vaccines compared with an imported HPV vaccine in women…
- Conditions
- HPV Infection, HPV Vaccine, Cervical Cancer Prevention
- Trial name
- NCT06137352
- Testing
- Follow up
- Where
- China
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Fujian Maternity and Child Health Hospital
Influenza
A Clinical Trial of Quadrivalent Influenza Virus Split Vaccine (MDCK Cells) for Individuals Aged 6 Months and Above.
To evaluate the safety of administering 1 or 2 doses of the quadrivalent influenza virus split vaccine (MDCK cells) (0.5ml/dose) in individuals aged 6 months and above.
- Trial name
- NCT06342349
- Testing
- Quadrivalent influenza virus split vaccine (MDCK cells), Quadrivalent influenza virus split vaccine (Chicken embryo), Phosphate buffer solution
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Shanghai Institute Of Biological Products
Delirium, Cognitive Impairment
Preoperative BAMCOG and Cortisol and Postoperative DeltaScan in AVR Patients (Aortic Valve Replacement)
There is lack of attention to preoperative cognitive function and delirium in elderly who underwent surgery. The investigators are investigating different tools that can help to screen for cognitive dysfunction and delirium in…
- Conditions
- Delirium, Cognitive Impairment, Cognitive Dysfunction, Cognitive Dysfunction, Postoperative
- Trial name
- NCT05209555
- Testing
- MoCA, BAMCOG, DeltaScan
- Where
- Netherlands
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Catharina Ziekenhuis Eindhoven
Orthomyxoviridae Infection, Influenza
Study of Inactivated, Split-Virion Influenza Vaccine Compared With the Reference Vaccine Vaxigrip® in the Elderly
Vaccination against influenza is a high priority for the elderly population who present the highest morbidity and mortality rate.
- Conditions
- Orthomyxoviridae Infection, Influenza, Myxovirus Infection
- Trial name
- NCT00383526
- Testing
- Inactivated, split-virion influenza vaccine
- Where
- 4 sites in Belgium, France and 2 more
- Volunteers
- 3,707 people, healthy volunteers welcome
- Sponsor
- Sanofi Pasteur, a Sanofi Company
Active Aging Individuals Aged 65 and Over, Aging
Italian Validation of the dNA Scale and Its Correlation With Neurocognitive Variables
The goal of this experimental multicentric intervention study is to validate, in Italian, the dynamic Neurocognitive Adaptation (dNA) Scale, which has already been validated in English, among a healthy elderly population (aged 65…
- Conditions
- Active Aging Individuals Aged 65 and Over, Aging, Mild Cognitive Impairment (MCI), Dementia
- Trial name
- NCT07533084
- Where
- 8 sites in Italy
- Volunteers
- 265 people, healthy volunteers welcome
- Sponsor
- Neuromed IRCCS
Preventive Effectiveness, Elderly With Qi-deficiency Constitution
The Preventive Effectiveness of the Individualized Jade Wind-Barrier Herbal Tea Bag on the Common Cold in Elderly With Qi-deficiency Constitution (CCJWBT): A Pragmatic Randomized Controlled Trial
Objectives Based on the individualized Jade Wind-Barrier Herbal Tea Bag intake after randomization, to evaluate the relationship of the individualized Jade Wind-Barrier Herbal Tea Bag intake and the improvement of Qi-deficiency…
- Conditions
- Preventive Effectiveness, Elderly With Qi-deficiency Constitution, The Individualized Jade Wind-Barrier Herbal Tea Bag, Common Cold
- Trial name
- CCJWBT (NCT05640570)
- Testing
- The individualized Jade Wind-Barrier Herbal Tea Bag
- Where
- China
- Volunteers
- 304 people, healthy volunteers welcome
- Sponsor
- Hong Kong Baptist University
Sarcopenia
Amino Acid Bioavailability in Healthy Elderly After Intake of an Oral Nutritional Supplement
In this study healthy older adults are requested to consume 4 different high-protein nutritional supplements. Each subject will visit the site 4 times and at every visit they will consume 1 of the 4 products after which a series…
- Trial name
- ArenA (NCT02013466)
- Testing
- Bolus ONS A, Bolus ONS B, Bolus ONS C
- Where
- Netherlands
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Nutricia Research
Influenza
Immunogenicity and Safety Study to Assess Influenza Vaccine Formulated With Haemagglutinin (HA) Antigen From Two Different Suppliers
The purpose of this study is to assess the humoral immune response and safety of the parenteral formulation of the 2010/2011-season virosomal subunit influenza vaccine Inflexal V using two different HA antigen suppliers (AdImmune…
- Trial name
- NCT01412281
- Testing
- Virosomal influenza vaccine (AdImmune HA Antigen), Virosomal influenza vaccine (CSL HA Antigen)
- Where
- Switzerland
- Volunteers
- 440 people, healthy volunteers welcome
- Sponsor
- Crucell Holland BV
Meningococcal Meningitis
A Clinical Trial to Evaluate the Immunogenicity and Safety of Group ACYW135 Meningococcal Conjugate Vaccine (CRM197) in Adults Aged 18 to 55 Years
This is a multicenter, randomized, double-blinded, positive controlled study to evaluate the lot-to-lot consistency, immunogenicity and safety of Group ACYW135 Meningococcal Conjugate Vaccine (CRM197) in adults aged 18 to 55…
- Trial name
- NCT06131554
- Testing
- batch 1 of Group ACYW135 Meningococcal Conjugate Vaccine (CRM197) (MCV4), batch 2 of MCV4, batch 3 of MCV4
- Where
- Indonesia
- Volunteers
- 1,480 people, healthy volunteers welcome
- Sponsor
- CanSino Biologics Inc.
Pulmonary Disease, Chronic Obstructive
A Study to Look at How GSK1325756 is Taken up by the Body When Given by Mouth When Stomach Acid is Reduced
This is a Phase I study to assess the combined effects of food and suppression of gastric acid secretion on the relative bioavailability of an immediate release (IR) tablet formulation and prototype bioenhanced formulations of…
- Trial name
- NCT01453478
- Testing
- GSK1325756
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Aging, Inflammation
Mitigating Mitochondrial RNA Release During Aging to Control Inflammation and Senescence
The MIRACLE study aims to investigate age-related mitochondrial dysfunction, mitochondrial RNA (mtRNA) release, inflammation, and cellular senescence in adult participants across three age groups.
- Conditions
- Aging, Inflammation, Healthy Ageing
- Trial name
- MIRACLE (NCT07596615)
- Testing
- Skin biopsy and venous blood sampling
- Where
- 2 sites in Italy
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Mario Negri Institute for Pharmacological Research
Muscle Weakness
The Effect of Alfacalcidol on Muscle Strength in Elderly Indonesian Women : A Randomized Controlled Trial
The age-related increase in falls is strongly associated with a decline in muscle strength by the mechanism of sarcopenia. There has been great interest in developing approaches to counteract the effects of sarcopenia, and…
- Trial name
- NCT02327091
- Testing
- alfacalcidol
- Where
- Indonesia
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Frailty, Sarcopenia
Comprehensive Geriatric Assessment in Adults Aged 40 Years and Older Living With HIV
People living with HIV are experiencing longer life expectancy due to effective antiretroviral therapy; however, they may develop age-related conditions earlier than the general population.
- Trial name
- HIV-AGE40 (NCT07453303)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital
Hepatitis E
A Phase Ⅳ Clinical Trial of the Recombinant Hepatitis E Vaccine (Escherichia Coli)(the Chronic Hepatitis B Patients )
This phase IV clinical study was designed to evaluate the immunogenicity and safety of Hecolin® in the chronic Hepatitis B patients on the clinical stability.
- Trial name
- NCT02964910
- Testing
- Recombinant Hepatitis E Vaccine (Escherichia Coli)
- Where
- China
- Volunteers
- 475 people, healthy volunteers welcome
- Sponsor
- Xiamen Innovax Biotech Co., Ltd
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