Clinical trials: Geriatric Disorders
Congestive Heart Failure
Preoperative Significant Clinical Findings Using Focused Ultrasound Examination
The purpose of this study is to determine whether a focused ultrasound examination for the heart, lungs and abdomen, preformed by a trained anesthesiologist, can reveal significant clinical findings in elderly patients before…
- Trial name
- NCT02824692
- Testing
- heart lungs and abdomen ultrasound
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Child Obesity
Using Video Gaming to Evaluate Front of Pack Labeling With Children
Regulated nutrition information is complex, using decimal places and percentages. Front of pack (FOP) labels provide simplified nutrition information on the front of packages.
- Trial name
- NCT03482336
- Testing
- Four FOP label designs
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Michigan State University
Alzheimer Disease, Dementia
Cognitive Impairment Cohort Study of the Elderly Population in SheMountain
This study is a prospective observational study, which involves a cohort of 2000 all-sex and all-ethnic people aged 60 years and above with permanent residence in Tianma area, SheMountain Town, Songjiang District (suburban area)…
- Conditions
- Alzheimer Disease, Dementia, Neurodegenerative Diseases, Cognitive Impairment
- Trial name
- SheMountain (NCT05667935)
- Where
- China
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Ruijin Hospital
Encephalitis, Tick-borne
FSME IMMUN NEW Follow-up to Study 208 in Volunteers Aged 16 to 66 Years
The aim of this study is to evaluate the safety of the third vaccination with FSME-IMMUN NEW in all volunteers who received both vaccinations in Baxter study 208 (safety study of FSME IMMUN NEW and ENCEPUR in healthy volunteers…
- Trial name
- NCT00161876
- Testing
- Tick-Borne Encephalitis (TBE) Vaccine (Inactivated)
- Where
- 8 sites in Poland
- Volunteers
- 3,973 people, healthy volunteers welcome
- Sponsor
- Pfizer
Tooth Decay
Impact of Fluoride Vanish Application in Dental Prevention for Elderly
This study questions the interest of fluoride varnish dental application in preventing tooth decay in a population of institutionalised elderly people.
- Trial name
- VERNIS (NCT01038817)
- Testing
- Duraphat
- Where
- France
- Volunteers
- 179 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Sarcopenia, Chronic Lower Back Pain
Prevalence and Factors Associated With Sarcopenia in Pre-retirement Aged Adults With Chronic Non-specific Lower Back Pain
To study the prevalence of sarcopenia in a pre-retirement group with chronic lower back pain and factors associated between sarcopenia and chronic lower back pain in the pre-retirement group.
- Trial name
- NCT05894213
- Where
- Thailand
- Volunteers
- 164 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Frailty, Frailty Syndrome
Prevalence, Determinants and Natural History of Frailty and Pre-frailty in Elderly People
Frailty syndrome (i.e. frailty) is a geriatric syndrome which relies on the reduction of multisystem reserve capacity. Frail people have a lower potential to respond to external stressors and various life incidents as well as…
- Conditions
- Frailty, Frailty Syndrome, Frail Elderly Syndrome, Fragility
- Trial name
- FRAILPOL (NCT04518423)
- Where
- Poland
- Volunteers
- 1,093 people, healthy volunteers welcome
- Sponsor
- The Opole University of Technology
Knee Osteoarthritis, Task Performance and Analysis
Knee Osteoarthritis, Motor Control, Risk of Falls and Virtual Reality
The goal of this clinical trial is to learn about knee osteoarthritis, functionality, and risk of falls in community-dwelling adults aged 60 years and older.
- Conditions
- Knee Osteoarthritis, Task Performance and Analysis, Accidental Falls, Virtual Reality
- Trial name
- NCT06362785
- Testing
- Virtual Reality, Therapeutic exercise
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Universidade da Coruña
Cardiovascular Diseases, Diabetes Mellitus
A Community Paramedicine Initiative for Older Adults Living in Subsidized Housing (CHAP-EMS/CP@Clinic)
Older adults living in subsidized housing report poorer health. Their age and low income make it harder for them to use community services.
- Trial name
- CHAP-EMS (NCT02152891)
- Testing
- CHAP-EMS/CP@clinic
- Where
- 5 sites in Canada
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- McMaster University
Hepatitis E
A Phase Ⅳ Clinical Trial of the Recombinant Hepatitis E Vaccine (Escherichia Coli)
This phase IV clinical study was designed to evaluate the safety and immunogenicity of the recombinant Hepatitis E vaccine(Hecolin®), manufactured by Xiamen Innovax Biotech CO., LTD., in healthy volunteers aged over 65 years of…
- Trial name
- NCT02417597
- Testing
- Recombinant Hepatitis E Vaccine (Escherichia Coli)
- Where
- China
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Xiamen Innovax Biotech Co., Ltd
RSV Infection
The Impact of Age on Adaptive Immunity in Adults Infected With Respiratory Syncytial Virus
This study will for the first time systematically investigate the immune responses in an elderly cohort challenged with a well-defined RSV inoculum.
- Trial name
- INFLAMMAGE (NCT03728413)
- Testing
- RSV A Memphis 37
- Where
- United Kingdom
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Migraine
Bioavailability of Variably Aged MK-0974 Tablets (MK-0974-038)(COMPLETED)
This study will evaluate the comparative bioavailability of three capsule formulations of MK-0974.
- Trial name
- NCT01209741
- Testing
- telcagepant potassium, MK-0974 5Mo5C, MK-0974 12Mo5C
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Avian Influenza
H7N9 Mix and Match With MF59 in Healthy Elderly Persons
This is a Phase II randomized, partially-blinded, controlled trial in 360 (up to 600) males and females, 65 years of age and older, who are in good health and meet all eligibility criteria.
- Trial name
- NCT02213354
- Testing
- MF59, Influenza Virus Vaccine, Monovalent A/H7N9 A/Shanghai/2/2013
- Where
- 10 sites in United States
- Volunteers
- 479 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Sarcopenia, Cardiovascular Disease
Egg Cholesterol Consumption, Blood Cholesterol and Skeletal Muscle Hypertrophy
The purpose of this study is to examine the effect of dietary cholesterol administered as whole egg or egg white (control)on muscle mass gain with resistance training in a young old population of men and women (age 50-69).
- Trial name
- NCT00260442
- Testing
- Resistance Training, Sedentary
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Texas A&M University
Malnutrition, Loneliness
Video Chat During Meals to Improve Nutritional Intake in Older Adults
The VideoDining study is a Stage IB behavioral intervention development project. The objectives are to determine the feasibility and acceptability of using video chat during mealtimes (VideoDining) in community-dwelling older…
- Trial name
- VideoDining (NCT04862312)
- Testing
- VideoDine
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Cornell University
COVID-19 Pandemic
The Immunogenicity and Safety of V-01-351/V-01D Bivalence Vaccine
It is a Single Arm, Open Label Clinical Study to Evaluate the Immunogenicity and Safety of Sequential Immunization of V-01-351/V-01D Bivalence Vaccine in Healthy Adults Aged 18 Years and Older After the Vaccination of 2 Doses of…
- Trial name
- Omicron (NCT05273528)
- Testing
- Recombinant SARS-CoV-2 Beta Variant Fusion Protein Vaccine/Recombinant SARS-CoV-2 Delta Variant Fusion Protein Vaccine
- Where
- China
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Livzon Pharmaceutical Group Inc.
Varicella-zoster Virus
Phase I Clinical Trial of Lyophilized Herpes Zoster mRNA Vaccine in Adults Aged 40 Years or Above
The primary objective of this study is to evaluate the tolerability, reactogenicity and safety of 2 injections (approximately 2 months apart) of three different dose levels of ABO1108 in adults aged 40 years or above.
- Trial name
- NCT07285265
- Testing
- ABO1108, SHINGRIX
- Where
- China
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Suzhou Abogen Biosciences Co., Ltd.
T-Cell Dysfunction, Chemotherapy Effect
Studying the Senescent T Cell Features and Its Relationship with the Chemotherapy Efficacy in Young TNBC
The goal of this observational study is to learn about the features of senescent T lymphocytes induced by chemotherapy and its relationship with the efficacy of neoadjuvant chemotherapy in young triple-negative breast cancer…
- Conditions
- T-Cell Dysfunction, Chemotherapy Effect, Adverse Events
- Trial name
- STFREiYTNBC (NCT06684054)
- Testing
- docetaxel, anthracycline, cyclophosphamide
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Sleep Disturbance, Cognitive Change
Integrating Systematic Data of Geriatric Medicine to Explore the Solution for Health Aging
This project aims to build up the comprehensive database of geriatric medicine for local Taiwanese.
- Conditions
- Sleep Disturbance, Cognitive Change, Aging
- Trial name
- NCT04207502
- Where
- 2 sites in Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Meningitis, Septicaemia
Understanding Pneumococcal Carriage and Disease
Pneumococcus is a bacteria that causes disease of the respiratory tract (pneumonia and middle ear infections), blood poisoning, and meningitis. It is frequently carried by people in back of the throat without symptoms.
- Conditions
- Meningitis, Septicaemia, Pneumonia
- Trial name
- NCT01996007
- Where
- United Kingdom
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- University of Oxford
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