Clinical trials: Geriatric Disorders
Schistosomiasis, Soil-Transmitted Helminthiasis
Using Community-Based Volunteers to Reach Non-Enrolled School Aged Children Through Community-Directed Treatment of Schistosomiasis in School-Aged Children in Rural Northern Ghana
Schistosomiasis and soil-transmitted helminhtiasis occur throughout the developing world and are most prevalent in the poorest communitites.
- Trial name
- NCT00463931
- Where
- Ghana
- Volunteers
- 916 people
- Sponsor
- DBL -Institute for Health Research and Development
Elderly, Muscle Loss
Effect of Lactobacillus Paracasei PS23 on Improving Aging and Muscle Loss in the Elderly
This study refers to the supplementation of PS23 in human experiments to help the elderly maintain muscle mass, delay muscle loss, promote physical activity, and delay the occurrence of disability and debilitation in elderly…
- Conditions
- Elderly, Muscle Loss, Depression, Anxiety
- Trial name
- NCT06062472
- Testing
- Probiotics, heat-treated of Lactobacillus paracasei HT-PS23
- Where
- Taiwan
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- Chi-Chang Huang
Hip Fracture Surgery, Postoperative Pain Management
Comparison of Sacral Erector Spinae Plane Block and Supra-Inguinal Fascia Iliaca Block for Analgesia After Hip Fracture Surgery
This study compares the postoperative analgesic effectiveness of Sacral Erector Spinae Plane Block (SESPB) and Supra-Inguinal Fascia Iliaca Block (SIFIB) in patients undergoing hip fracture surgery.
- Conditions
- Hip Fracture Surgery, Postoperative Pain Management, Regional Anesthesia, Elderly Patients
- Trial name
- NCT07081867
- Testing
- Supra-inguinal Fascia Iliaca Block (SIFIB), Sacral Erector Spinae Plane Block (SESPB)
- Where
- Turkey (Türkiye)
- Volunteers
- 77 people
- Sponsor
- Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
Unrecognized Condition
Effect of CPAP Treatment on the Elderly With Mild to Moderate Sleep Apnea
Objective: To analyze the impact of CPAP treatment on cognitive, clinical and quality of life domains in patients over 70 years of age with mild-to-moderate OSA Primary Outcome: Epworth scale and QSQ domains Secondary Outcomes…
- Trial name
- NCT03079466
- Testing
- CPAP
- Volunteers
- 96 people
- Sponsor
- Hospital Universitario Doctor Peset
Xerostomia, Hypertension
Efficacy of Novel Edible Gel-based Artificial Saliva in Thai Geriatric Populations With Systemic Diseases
Elderly people usually have systemic diseases and take medications that can cause dry mouth. The purpose of this study is to determine whether continuous use of edible, gel-based artificial saliva in geriatric population with dry…
- Conditions
- Xerostomia, Hypertension, Diabetes Mellitus
- Trial name
- NCT02317172
- Testing
- Gel-based artificial saliva
- Where
- Thailand
- Volunteers
- 120 people
- Sponsor
- Dental Innovation Foundation Under Royal Patronage
Plaque Accumulation
Water Flossing Versus Dental Floss for Oral Hygiene in Children Aged 10-15 Years: A Randomized Trial
The goal of this Randomized Clinical Trial is to compare the effectiveness of water flossing versus regular flossing in reducing dental plaque in children aged 10-15 years.
- Trial name
- NCT07469839
- Testing
- Unflavored, unwaxed regular dental floss (Oral-B, USA), Water flosser (Waterpik Cordless Plus Water Flosser, USA)
- Where
- Saudi Arabia
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- King Abdulaziz University
Aged, Asymptomatic Condition
Classification of the Sagittal Profile of the Spine in Asymptomatic Elderly Subjects
Principal aim The main purpose of the study is to describe the distribution of the sagittal profile in elderly subjects in order to bridge the gap present in this type of screening, evaluated in the literature for adults only…
- Trial name
- EOS60 (NCT03237039)
- Testing
- X-ray examination, fall-risk assessment, gait cycle analysis
- Where
- Italy
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Coronary Artery Disease
Effects of Exercise in Patients With Coronary Artery Disease Aged 80 Years or Older
The purpose of this study is to investigate the effects of exercise for patients with coronary artery disease (CAD) aged 80 years and older, with special reference to maximum aerobic capacity, muscle endurance, physical…
- Trial name
- NCT02025257
- Testing
- Exercise
- Where
- Sweden
- Volunteers
- 34 people
- Sponsor
- Sahlgrenska University Hospital
Burns Chest Left Lateral, Burns Chest Right Lateral
Virtual Reality Distraction Technique to Improve Chest Burns With Acute Respiratory Distress Syndrome
Inhalation of toxic gases and chemical irritants during the fire leads to damage to the respiratory tract or the alveolar tissue, which is known as smoke inhalation injury.
- Conditions
- Burns Chest Left Lateral, Burns Chest Right Lateral, Acute Respiratory Distress Syndrome
- Trial name
- NCT05692557
- Testing
- Virtual reality, Progressive muscle relaxation
- Where
- Saudi Arabia
- Volunteers
- 60 people
- Sponsor
- Prince Sattam Bin Abdulaziz University
Breast Cancer
Surgery With or Without Lymph Node Removal in Treating Older Women With Stage I or Stage IIA Breast Cancer
RATIONALE: Removing axillary lymph nodes may be effective in stopping the spread of breast cancer cells. It is not yet known if surgery to remove breast cancer is more effective with or without lymph node removal.
- Trial name
- 10-93 (NCT00002528)
- Testing
- tamoxifen citrate, conventional surgery, radiation therapy
- Where
- 21 sites in Australia, Hungary and 7 more
- Volunteers
- 473 people
- Sponsor
- ETOP IBCSG Partners Foundation
Transcranial Alternating Current Stimulation, Aging
Effects of Gamma-tACS on Memory and Sleep
The purpose of this clinical trial is to investigate the feasibility and efficacy of non-invasive transcranial alternating current stimulation (tACS) at gamma frequency in enhancing memory recall and modulating sleep network…
- Conditions
- Transcranial Alternating Current Stimulation, Aging, Cognitive Decline, Memory
- Trial name
- NCT05907707
- Testing
- Gamma transcranial alternating current stimulation, Control transcranial alternating current stimulation, EEG headband
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Heart Disease
A Clinical Trial in Higher Risk Geriatric Patients Undergoing OHSP
To provide information on parameters needed to design a subsequent Phase III confirmatory trial and to assess the safety and efficacy of the acute use of CMI X-11S in high-risk geriatric patients undergoing open-heart surgical…
- Trial name
- MiniMetrxics (NCT00500929)
- Testing
- CMI X-11S
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- Cardiometabolics
Delirium, Delirium in Old Age
Researching Efficient Approaches to Delirium Identification-Sustaining Effective Translation
The goal of this step-wedge trial is to test the implementation of daily nurse screening for delirium in routine care and its impact on outcomes and complications in hospitalized older adults admitted to 6 general…
- Conditions
- Delirium, Delirium in Old Age, Delirium With Dementia, Delirium Superimposed on Dementia
- Trial name
- READI-SET-GO (NCT05915377)
- Testing
- READI-SET GO UB-CAM delirium screening into EHR
- Where
- 2 sites in United States
- Volunteers
- 1,050 people
- Sponsor
- Penn State University
COVID-19
Immunogenicity And Safety of COVID-19 Vaccine , Inactivated Co -Administration With EV71 Vaccine (Vero Cell)
This study is a randomized and controlled Phase IV clinical trial of the COVID-19 vaccine (Vero cell), Inactivated manufactured by Sinovac Research \& Development Co., Ltd.
- Trial name
- NCT05107557
- Testing
- Experimental Group
- Where
- 2 sites in China
- Volunteers
- 520 people, healthy volunteers welcome
- Sponsor
- Sinovac Biotech Co., Ltd
Bronchopulmonary Dysplasia, Chronic Lung Disease of Newborn
Indoor Air Quality and Respiratory Morbidity in School-Aged Children With BPD
Investigators want to learn the role of indoor environmental exposures on respiratory symptoms, and, separately, on lung function deficits in school-aged children with bronchopulmonary dysplasia (BPD).
- Conditions
- Bronchopulmonary Dysplasia, Chronic Lung Disease of Newborn, Environmental Exposure
- Trial name
- AeroBPD (NCT04107701)
- Where
- United States
- Volunteers
- 165 people
- Sponsor
- Boston Children's Hospital
Metabolic Syndrome X, Cardiovascular Problems in Elderly
Effect of Blood Flow Restriction on Cardiovascular Function in Elderly with Metabolic Syndrome X
The purpose of the study is to investigate the effect of aerobic exercise with Blood flow restriction training (BFR) on cardiovascular function and quality of life in hypertensive elderly patients.
- Trial name
- NCT06877130
- Testing
- Aerobic exercise with BFR, Aerobic training
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Attention Deficit Hyperactivity Disorder (ADHD)
Safety and Efficacy Study of SHP465 in Adults Aged 18-55 Years With Attention-deficit/ Hyperactivity Disorder (ADHD)
The study is designed to evaluate the efficacy and safety of each dose of SHP465 (12.5 and 37.5 mg) given to participants daily in the morning compared to placebo in the treatment of adults aged 18 to 55 years diagnosed with ADHD.
- Trial name
- NCT02604407
- Testing
- SHP465 12.5mg capsules (one capsule daily), SHP465 12.5mg, 25mg, or 37.5mg capsules (one capsule daily)
- Where
- 45 sites in United States
- Volunteers
- 275 people
- Sponsor
- Shire
Aging
NESA Microcurrents on Quality of Life in Geriatric Patients
In recent years, the population of older adults (MA) in the world has been increasing, due to the increase in life expectancy and the decrease in the fertility rate.
- Trial name
- NCT05800431
- Testing
- Non-invasive neuromodulation through the Nesa device
- Where
- Spain
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Las Palmas de Gran Canaria
Colon Cancer Patients Receiving Chemotherapy in the Adjuvant or Metastatic Setting, Aged 70 or Older
MOST: Mediterranean Oncology Senior Tests
MOST is a longitudinal study whose aim is to test the hypothesis that frailty markers are better at detecting vulnerable patients and that they are a better "Adverse Events" predictive tool than the CGA (Comprehensive Geriatric…
- Trial name
- MOST (NCT02148731)
- Testing
- Frailty markers
- Where
- 8 sites in France
- Volunteers
- 180 people
- Sponsor
- Association Sud pour la Recherche en Oncogériatrie
Frailty Syndrome, Fall in Nursing Home
Digital Intelligent Assistant for Nursing Application
This is an observational study that intends to compare falls or fall-risk related alarms derived from a three-dimensional sensor system with the clinical reality definded by attending nurses.
- Conditions
- Frailty Syndrome, Fall in Nursing Home, Dementia, Delirium in Old Age
- Trial name
- DIANA (NCT04393272)
- Testing
- Three dimensional sensor system designed for fall detection (Fearless)
- Where
- Switzerland
- Volunteers
- 25 people
- Sponsor
- Geriatrische Klinik St. Gallen
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