Clinical trials: Geriatric Disorders
Pneumonia
Ceftriaxone Versus Chloramphenicol for Treatment of Severe Pneumonia in Children
Acute lower respiratory tract infections are a leading cause of morbidity and mortality in sub Saharan Africa. The World Health Organisation (WHO) still recommends intravenous chloramphenicol for the treatment of severe pneumonia…
- Trial name
- NCT00372541
- Testing
- ceftriaxone
- Where
- 4 sites in Uganda
- Volunteers
- 348 people
- Sponsor
- Makerere University
Anxiety, Anxiety Disorders
Transdiagnostic, Cognitive and Behavioral Intervention for in School-aged Children With Emotional and Behavioral Disturbances
Background Impairing emotional and behavioural problems are common in children and adolescents and mark a three-fold increased risk of mental disorder in young adulthood.
- Conditions
- Anxiety, Anxiety Disorders, Depressive Symptoms, Depressive Disorders
- Trial name
- MindMyMind RCT (NCT03535805)
- Testing
- Mind My Mind (MMM), Treatment as Usual (TAU)
- Where
- Denmark
- Volunteers
- 396 people
- Sponsor
- Mental Health Centre Copenhagen, Bispebjerg and Frederiksberg Hospital
Seasonal Influenza
Safety and Immunogenicity, Inactivated Split Influenza Vaccine, Using the Strain Composition 2009/2010
This study is an annual trial for registration of inactivated split influenza vaccine with strain composition for season 2009/2010.
- Trial name
- NCT00945841
- Testing
- inactivated split influenza vaccine
- Where
- 3 sites in Germany
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Novartis
Aging, Elderly
Successful Aging and Age-related Decline
Recent studies have shown promising cognitive and physical interventions aimed at slowing down ageing-related declines in quality of life, but they lack strong ecological validity (brief durations, unrealistic goals, no…
- Conditions
- Aging, Elderly, Cognitive Decline, Physical Decline
- Trial name
- MyAgeWell (NCT06376656)
- Testing
- Cognitive stimulation, Physical activity
- Where
- Malaysia
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Sunway University
Osteoarthritis of the Knee
Structured Non-operative Treatment of Knee Osteoarthritis
The purpose of this study is to test whether an algorithm for systematic non-surgical treatment consisting of corrective insoles, neuromuscular training, weight loss, patient education and pharmacological treatment with…
- Trial name
- NCT01535001
- Testing
- Neuromuscular training (NEMEX-TJR), Information, Paracetamol
- Where
- 3 sites in Denmark
- Volunteers
- 100 people
- Sponsor
- Northern Orthopaedic Division, Denmark
Chronic Kidney Disease (CKD), Elderly
Escitalopram and the Risk of Serious Adverse Events
The goal of this population-based cohort study is to assess the safety of initiating a new outpatient prescription of 10mg/day of Escitalopram (higher dose) compared to 5 mg/day (lower dose) in adults over the age of 65 with low…
- Conditions
- Chronic Kidney Disease (CKD), Elderly, Outpatient
- Trial name
- NCT07274241
- Testing
- Escitalopram
- Where
- Canada
- Volunteers
- 12,145 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Hip Fractures, Muscular Atrophy
Effects of Exercise on Markers of Inflammation in Skeletal Muscle in Elderly Hip Fracture Patients
Decreased skeletal muscle mass is a prevalent condition among the elderly, and an important cause of disability and functional decline.
- Trial name
- NCT00006194
- Testing
- Exercise
- Where
- United States
- Sponsor
- National Center for Research Resources (NCRR)
Sarcopenia in Elderly, Sarcopenia
A Study of AMC6156 in People With Sarcopenia
This clinical trial aims to find out whether AMC6156 can improve physical function and is safe in older adults with sarcopenia. Participants will take AMC6156 or a placebo daily for 12 weeks, and their movement, strength, and…
- Trial name
- NCT07072195
- Testing
- AMC6156 0.1mg, AMC6156 0.3mg, AMC6156 1.0mg
- Where
- 4 sites in South Korea
- Volunteers
- 80 people
- Sponsor
- Animuscure Inc.
Diabetic Retinopathy, Diabetes Mellitus, Type 2
Confronting Unequal Eye Care in Pennsylvania
Pt. 1 Diabetic retinopathy is a common eye condition among diabetic adults and can lead to severe vision impairment and even blindness.
- Conditions
- Diabetic Retinopathy, Diabetes Mellitus, Type 2, Glaucoma
- Trial name
- NCT01179555
- Testing
- Behavioral Activation, Supportive Therapy
- Where
- 3 sites in United States
- Volunteers
- 206 people
- Sponsor
- Wills Eye
Pneumonia, Family Caregivers
Effectiveness of Chatbot for Improving Caregiving Outcomes in Primary Caregivers of Geriatric Pneumonia Patients: A Study on Knowledge, Attitude and Practice.
Pneumonia is a leading cause of death and hospitalization among the elderly in Taiwan. High-quality home care is essential to recovery and reducing readmission, yet primary caregivers often lack the specific skills needed, such…
- Conditions
- Pneumonia, Family Caregivers, Knowledge, Attitudes, Practice, Chatbot
- Trial name
- NCT07463443
- Testing
- Chatbot with Educational Videos, Traditional Paper-based Education
- Where
- Taiwan
- Volunteers
- 150 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Papillomavirus Infections
Efficacy Against Oral Persistent Infection, Immunogenicity and Safety of the 9-valent Human Papillomavirus Vaccine (9vHPV) in Men Aged 20-45 Years (V503-049)
The purpose of this study is to evaluate the efficacy, immunogenicity and safety of the 9vHPV vaccine in men 20 to 45 years of age.
- Trial name
- NCT04199689
- Testing
- 9vHPV Vaccine
- Where
- 103 sites in United States, Belgium and 14 more
- Volunteers
- 6,033 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Influenza
Safety Study of Four Candidate Influenza Vaccines to Prevent Influenza Disease in the Elderly Population
As influenza vaccine efficacy is reported to be lower in elderly subjects compared to healthy adults, probably as a result of immunosenescence, there is a desire to devise ways to increase the current vaccines efficacy for this…
- Trial name
- NCT00318149
- Testing
- Fluarix, Fluarix-AS25, Fluarix-AS50
- Where
- Belgium
- Volunteers
- 425 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Malnutrition, Aged
Nutritional Status and Medication Treatment in Home-dwelling Older Adults
The project "Nutrition and Medication management in home-dwelling older adults" consist of two separate studies witch are described in the same study protocol. This is the first study in this Project.
- Conditions
- Malnutrition, Aged, Polypharmacy
- Trial name
- NCT04229238
- Where
- Norway
- Volunteers
- 400 people
- Sponsor
- University of Oslo
Postoperative Cognitive Dysfunction
Implementation of a Cognitive Training Program to Reduce the Risk of Postoperative Cognitive Dysfunction
Background: The postoperative cognitive dysfunction (POCD) is a frequent complication, often underestimated and leads to a negative impact on the quality of life for patients and their families.
- Trial name
- NCT03620968
- Testing
- cognitive training
- Where
- Spain
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- Centro Medico Teknon
Influenza
Systems Biology of Trivalent Influenza Vaccine (TIV) in Young and Elderly
Vaccination is the most effective way of preventing infectious diseases. Despite the success of vaccines in general, vaccines induce diminished antibody responses and lower protection in the elderly in particular.
- Trial name
- NCT01232868
- Testing
- trivalent Influenza vaccine (TIV)
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Emory University
Herpes
A Phase I Clinical Trial of Recombinant Herpes Zoster Vaccine (CHO Cell)
To evaluate the safety and tolerability of different dosages of recombinant zoster vaccine (CHO cell) when administered to adults aged 40 years and older.
- Trial name
- NCT07633197
- Testing
- Recombinant Herpes Zoster Vaccine
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Changchun BCHT Biotechnology Co.
Abdominal Obesity, Metabolic Syndrome
WAVE Study- Walking and Aging in VErona Study
Monocentric unblinded two parallel-group randomized controlled trial to evaluate the effect of diet with or without Nordic Walking on weight loss, physical performance and cardiovascular risk factors in overweight and obese…
- Conditions
- Abdominal Obesity, Metabolic Syndrome, Disability Physical, Sarcopenic Obesity
- Trial name
- WAVE (NCT03212391)
- Testing
- Diet, Walking, Nordic Walking
- Where
- Italy
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliera Universitaria Integrata Verona
Aging, Cellular Senescence
BIOANCIENT: Cohort of Centenarians in Navarra (1926-1927)
Demographic aging is a growing global challenge, driven by increasing life expectancy and declining birth rates, with projections indicating that more than 30% of the European population will be over 65 years old by 2100.
- Conditions
- Aging, Cellular Senescence, Biomarkers / Blood, Age-Related Diseases
- Trial name
- BIOANCIENT (NCT07707297)
- Where
- Spain
- Volunteers
- 333 people
- Sponsor
- Fundacion Miguel Servet
Nursing Caries, Old Age; Debility
Multifactorial Study of the Relationship Between the Conditions of Life and the Incidence of Risk of Falling
HYPOTHESIS: The incidence of risk of falls is related to the living conditions of elderly people in the community. OBJECTIVES: To study the relationship between living conditions and the incidence of risk of falls in older adults…
- Conditions
- Nursing Caries, Old Age; Debility, Aging Disorder
- Trial name
- NCT04301713
- Testing
- Evaluation of rik of falls
- Where
- Spain
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of Salamanca
Vitamin d Deficiency, Vitamin B 12 Deficiency
ETOL-Elderly Study of the Efficiency of the Innovative Food Supplement in Elderly Adults
The aim of this pilot study is to conduct a study on geriatric population in Slovenia (non-users of dietary supplements/medicines with vitamine D, vitamin B12 and protein) and assess deficiency of selected nutrients, and to…
- Conditions
- Vitamin d Deficiency, Vitamin B 12 Deficiency, Protein Deficiency
- Trial name
- ETOL-Elderly (NCT05661006)
- Testing
- Use of food supplement
- Where
- Slovenia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Institute of Nutrition, Slovenia (Nutris)
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