Clinical trials: Geriatric Disorders
Anemia, Delirium
Elderly With Hip Fracture and Perioperative Hemoglobin and Perfusion Index Levels
The overall aim of the study is to investigate the time difference in the diagnosing of anemia among elderly with hip fracture, between measurements with standard blood samples and non-invasive SpHb-measuring.
- Trial name
- NCT02838706
- Testing
- Surgery for hip fracture
- Where
- Denmark
- Volunteers
- 50 people
- Sponsor
- Hvidovre University Hospital
Diffuse Large Cell Lymphoma
R-CHOP-14 Versus R-CHOP-21 and Darbepoetin Alpha in Patients Aged 60-80 Years With Diffuse Large B-cell Lymphoma
This study is a multicentric randomized trial evaluating the efficacy and safety of R-CHOP given every 14 days compared to R-CHOP given every 21 days in association or not with darbepoetin alfa in order to maintain hemoglobin…
- Trial name
- NCT00144755
- Testing
- Darbepoetin alfa
- Where
- 14 sites in Belgium, France and 1 more
- Volunteers
- 600 people
- Sponsor
- Lymphoma Study Association
Dysphagia
Effects of IOPI on Swallowing Function and Functional Status in Geriatric Patients
This project is an exploratory study that aims to investigate the effects of IOPI therapy on the swallowing function and tongue strength of geriatric patients in a geriatric ward in an acute hospital.
- Trial name
- NCT05074784
- Testing
- IOPI Therapy, Tongue Depressor Traditional Intervention
- Volunteers
- 84 people
- Sponsor
- Khoo Teck Puat Hospital
Sleep Initiation and Maintenance Disorders
Efficacy Study of EVT 201 in the Treatment of Elderly Patients With Daytime Sleepiness
The purpose of this study is to determine whether a compound known as EVT 201 is effective in treating elderly patients diagnosed with primary insomnia who also have moderate daytime sleepiness.
- Trial name
- NCT00401284
- Testing
- EVT 201
- Where
- 22 sites in United States
- Volunteers
- 135 people
- Sponsor
- Evotec Neurosciences GmbH
Hematologic Malignancy
Patient-Centered Care for the Older Adult With Hematologic Malignancy
This research study is evaluating if co-management by a geriatrician embedded in the oncology clinic can improve outcomes for frail older adults with blood cancers.
- Trial name
- NCT02359838
- Testing
- Baseline Geriatric Screening/Assessment, Geriatrician Co-Management
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- Dana-Farber Cancer Institute
Type2 Diabetes
Exercise Dose-response for Diabetes in the Elderly
One-center randomized, three-arm, parallel, superiority, controlled trial in 132 elderly outpatients with type 2 diabetes. Two different combined exercise training doses (300min/week vs 150min/week) will be compared against usual…
- Trial name
- EDDIE (NCT03423108)
- Testing
- G150, G300
- Where
- Brazil
- Volunteers
- 132 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Pain, Hypoglycemia
Outcomes Study of MTM in a Medicare ACO
This is a non-randomized, prospective, quasi-experimental study designed to assess the impact of pharmacist-provided medication management on total cost of care and clinical outcomes (ie, hospitalizations, emergency department…
- Trial name
- NCT02875925
- Testing
- MTM
- Where
- United States
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- HealthEast Care System
Irritable Bowel Syndrome, Diarrhea- Irritable Bowel Syndrome
To Study the Effect of Short-chain Fructooligosaccharides in Women With Irritable Bowel Syndrome
To evaluate whether there is clinical improvement through the scales (Bristol, IBS severity score, and IBS quality of life) in women with irritable bowel syndrome after administration of SC-FOS (short-chain…
- Conditions
- Irritable Bowel Syndrome, Diarrhea- Irritable Bowel Syndrome, Constipation-predominant Irritable Bowel Syndrome
- Trial name
- NCT05941650
- Testing
- Short Chain Fructooligosaccharides, Corn Starch
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universidad Autonoma de Chihuahua
Pneumonia, Respiratory Infection
Chlorhexidine & Pneumonia in Nursing Home Residents
The purpose of this study is determine if topical oral application of a chlorhexidine antimicrobial spray will significantly reduce pneumonia and respiratory infections, and improve oral health compared to a placebo solution in…
- Trial name
- NCT00841074
- Testing
- chlorhexidine
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of Louisville
Acute Myelogenous Leukemia, Myelodysplastic Syndrome
Study of Dasatinib and All-Trans Retinoic Acid for Relapsed/Refractory and/or Elderly Patients With Acute Myelogenous Leukemia (AML) or Myelodysplastic Syndrome
This is an open label, prospective, single institution dose-escalation study. The patient population includes non-induction candidate elderly patients with AML or MDS and/or patients with high-risk or relapsed/refractory AML or…
- Trial name
- NCT00892190
- Testing
- dasatinib (SPRYCEL), all trans retinoic acid (VESANOID)
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- University of Pittsburgh
Generalized Anxiety Disorder
Computerized Cognitive Training in Middle-Aged Adults With Generalized Anxiety Disorder: A Pilot Study
The purpose of this research is to look at the effects of computerized cognitive training on anxiety, sleep, mental abilities (cognition), and other aspects of daytime functioning, such as arousal.
- Trial name
- COGMA (NCT04421690)
- Testing
- Cognitive Training, Trivia Training
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Rhinitis, Allergic, Perennial
Fexofenadine Study On Filipino Children for The Relief of Perennial And Intermittent Allergic Rhinitis
To determine the safety and efficacy of Fexofenadine (Telfast®) 30mg pediatric tablets on Filipino children aged 6 to 11 for the relief of symptoms associated with perennial and intermittent allergic rhinitis.
- Trial name
- NCT00741897
- Testing
- Fexofenadine
- Where
- Philippines
- Volunteers
- 264 people
- Sponsor
- Sanofi
Diphtheria, Tetanus and Acellular Pertussis, Epidemic Meningitis
Clinical Trial of the Adsorbed Acellular Pertussis (Tricomponent) DTaP-Haemophilus Influenzae Type b (Conjugate)-ACYW135 Group Meningococcal (Conjugate) Combined Vaccine
This clinical trial is conducted in two parts. Part One employs a randomized, partially blinded, dose-escalation, partially active-controlled design. Part Two utilizes a randomized, blinded, placebo-controlled design.
- Conditions
- Diphtheria, Tetanus and Acellular Pertussis, Epidemic Meningitis, Haemophilus Influenzae Type B Infection
- Trial name
- NCT07203755
- Testing
- Adsorbed Acellular Pertussis (3-Component) Diphtheria-Tetanus-Pertussis-Haemophilus influenzae type b (Conjugate)-Meningococcal Group ACYW135 (Conjugate) Combined Vaccine (DTcP-Hib-MCV4), DTcP-Hib-MCV4, Adsorbed Acellular Pertussis (3-Component) Diphtheria-Tetanus-Pertussis (DTcP)
- Where
- China
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- CanSino Biologics Inc.
Chronic Lymphocytic Leukemia
Observational Study of Low Dose FCR in Elderly/Comorbid CLL/SLL: The Q-lite Project
FCR (fludarabine, cyclophosphamide, rituximab) combination is currently accepted as the gold standard in treatment of younger and physically fit CLL patients.
- Trial name
- Q-lite (NCT02156726)
- Testing
- low-dose FCR
- Where
- 7 sites in Czechia
- Volunteers
- 200 people
- Sponsor
- Czech CLL Study Group
Post-traumatic Stress Disorder, Hypertension
TMS for PTSD and Blood Pressure
In this randomized clinical trial, we will test the short and longer term effects of repetitive transcranial magnetic stimulation (TMS) on blood pressure among reproductive aged female participants with elevated symptoms of…
- Trial name
- NCT05512143
- Testing
- Transcranial magnetic stimulation
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Lifespan
Colonic Disease, Intestinal Disease
Comparison for Efficacy and Safety of Bowel Preparation Between Oral Sulfate Table and 2L-polyethylene Glycol/Ascorbate in Elderly
This study compares the effectiveness and stability of intestinal tablet (OST), an oral sulfate table (OST), developed in the form of pills, with 2L-PEG/Asc for examinees aged 70 or older who are scheduled for colonoscopy.
- Trial name
- NCT05249335
- Testing
- OST, 2L-PEG/Asc
- Volunteers
- 256 people, healthy volunteers welcome
- Sponsor
- Pharmbio Korea Co., Ltd.
Congestive Heart Failure
Testosterone Improves Exercise Oxygen Uptake, Insulin Resistance and Muscle Strength in Elderly Patients With Chronic Heart Failure
Background: Patients with congestive heart failure (CHF) show muscle mass wasting and decreased testosterone levels. Long-term testosterone supplementation improves walking distance and glucose metabolism of patients CHF.
- Trial name
- NCT00512408
- Testing
- testosterone
- Where
- Italy
- Sponsor
- IRCCS San Raffaele
Focus of Study
Can the Hypertrophy of Contralateral Testis Predict the Absence of the Non-palpable Testis in the Boys Aged From 6months to 18months of Age ?
The aim of this study is to verify whether the hypertrophy of contralateral testis may predict the absence of the non-palpable testis in the boys younger than 24months of age.
- Trial name
- NCT02203318
- Where
- South Korea
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Aging, Sarcopenia
Effects of Whole-body Electrical Muscle Stimulation Exercise on Spinal Motoneuronal Activation in Older Adults
During this pilot study, the investigators will examine the effects of whole-body electrical muscle stimulation exercise (WB-EMS Exercise) on motoneuronal activation in healthy adults, which typically decreases with age.
- Conditions
- Aging, Sarcopenia, Sarcopenia in Elderly
- Trial name
- NCT06689618
- Testing
- Exercise
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Osteoporosis, Sarcopenia
Osteoporosis and Sarcopenia Prevention in Middle-Aged Population
This initiative is designed to yield substantial and multi-level benefits for the Hong Kong community by pioneering a transformative model of preventive healthcare.
- Trial name
- FORTIFY (NCT07611097)
- Testing
- Intervention Group, Control Group
- Where
- Hong Kong
- Volunteers
- 8,336 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
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