Clinical trials: Geriatric Health
Myelodysplastic Syndromes, Leukemia Myeloid Acute
Validation of a Comprehensive Health Status Assessment Scale in Elderly Patients (≥ 65 Years) With Hematological Malignancies
The elderly comprise the most prevalent population in oncology practice. The available evidence suggests that old patients are undertreated patients, mainly because of their advanced age, regardless of whether they are highly…
- Conditions
- Myelodysplastic Syndromes, Leukemia Myeloid Acute, Multiple Myeloma, Leuklemia, Lymphocytic, Chronic
- Trial name
- GAH (NCT02164071)
- Testing
- Geriatric Assessment of Health Status Scale administration
- Where
- 22 sites in Spain
- Volunteers
- 363 people
- Sponsor
- Celgene
Healthy
A Study to Evaluate the Safety, Tolerability and Immunogenicity of Two Vaccinations of Ad26.RSV.preF One Year Apart in Adults Aged 60 Years and Older in Stable Health
The purpose of this study is to assess the safety and tolerability of 2 single doses of either 5*10^10 viral particles (vp) or 1*10^11 vp of Ad26.RSV.preF, administered intramuscularly to elderly adults given approximately 12…
- Trial name
- NCT02926430
- Testing
- Ad26.RSV.preF 5*10^10 vp, Ad26.RSV.preF 1*10^11 vp
- Where
- United States
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Janssen Vaccines & Prevention B.V.
Healthy
A Study Investigating the Effect of Floradapt Mature Immune Defense on Nutrient Uptake and Digestive Health in a Healthy Elderly Population
This trial will be investigating the effect for Floradapt Mature Immune Defense on nutrient uptake and digestive health in a healthy elderly population.
- Trial name
- NCT04147923
- Testing
- Floradapt Mature Immune Defense + Multivitamin
- Where
- Canada
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Kaneka Americas Holding Inc.
Metabolic Abnormality, Metabolic Disorders
Evaluating Metabolic Health in People Aged 18 to 60 by Nutrilite Metabolic Health Index
The goal of this observational study is to evaluate Metabolic Health by fit analysis between calculated Nutrilite Metabolic Health Index and the result of Metabolomics analysis from blood plasma samples in healthy adult…
- Trial name
- NCT07161557
- Testing
- No Intervention: Observational Cohort
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Amway (China) R&D Center
Healthy
A Study to Evaluate the Safety and Immunogenicity of Seasonal Influenza Vaccine and an Adenovirus Serotype 26- Based Vaccine Encoding for the Respiratory Syncytial Virus Pre-fusion F Protein (Ad26.RSV.preF), With and Without Co-administration, in Adults Aged 60 Years and Older in Stable Health
The purpose of this study is to demonstrate the non-inferiority of the concomitant administration of an adenovirus serotype 26- based vaccine encoding for the respiratory syncytial virus pre-fusion F protein (Ad26.RSV.preF) and…
- Trial name
- NCT03339713
- Testing
- Ad26.RSV.preF, Fluarix
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Janssen Vaccines & Prevention B.V.
Microbiome Dysbiosis, Gut Health
Colon-delivered Riboflavin and Gut Microbiota Composition
Recent studies suggest B-vitamins such as riboflavin to possess prebiotic-like effects. However, there is still a lack of understanding of the exact host health benefits vs. conventional systemically available vitamin forms.
- Trial name
- CONCOL (NCT07093463)
- Testing
- Colon-delivered riboflavin, Conventional riboflavin, Microcrystalline Cellulose
- Where
- Germany
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- dsm-firmenich Switzerland AG
Tension Headaches, Stress
Temple Massager System Study in Women Ages 35-65
The goal of this observational study is to learn how the Temple Massager System affects stress, emotional wellbeing, sleep, and quality of life in women aged 35 to 65.
- Conditions
- Tension Headaches, Stress, Sleep Quality, Quality of Life
- Trial name
- NCT07639658
- Testing
- Temple Massager System
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Meisch Temple Massager, Inc.
Frail Elderly Syndrome, Aging
Autologous Stem/Stromal Cellular Stromal Vascular Fraction (cSVF) In Frailty-Aging Processes
With increasing age and health issues associated with aging, many systemic cellular and structural changes are known to occur. The intent of this trial is to determine the safety and efficacy of delivery of autologous cellular…
- Conditions
- Frail Elderly Syndrome, Aging, Degenerative Disease
- Trial name
- GARM-W (NCT03514537)
- Testing
- Microcannula harvest adipose stromal tissues, Centricyte 1000, Sterile Normal Saline IV Deployment of cSVF
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Healeon Medical Inc
Malnutrition
The Nutritional Health for the Elderly Reference Centre Study (The NHERC Study)
The prevalence of malnutrition among the elderly in Asia is high. The objective of this randomized, parallel, placebo controlled, double-blind study is to evaluate the effects of consuming an adult ONS plus dietary counseling…
- Trial name
- NHERC (NCT03245047)
- Testing
- Oral Nutritional Supplement with AN 777, Oral Nutritional Supplement
- Where
- 4 sites in Singapore
- Volunteers
- 811 people
- Sponsor
- Abbott Nutrition
Mild Gastrointestinal Symptoms in Healthy Adults, Low-grade Chronic Inflammation
Fungal Fiber for Gut Health
This study compares effects of plant based fiber vs fungi based fiber on clinical outcomes related to gut function (immunity, emotions, stress) and explores the role of gut microbiome structure and function on individual…
- Conditions
- Mild Gastrointestinal Symptoms in Healthy Adults, Low-grade Chronic Inflammation, Stress, Gut Health
- Trial name
- FUN4GUT (NCT06404749)
- Testing
- fungal fiber, inulin
- Where
- Argentina
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Future Biome SA
Hearing Loss
Evaluation of the Benefits for Overall Health Following Cochlear Implant Treatment in the Elderly Population
The purpose of this study is to show that cochlear implant treatment improves the overall health related quality of life and general well-being in elderly individuals.
- Trial name
- NCT03072862
- Testing
- Commercial Nucleus Cochlear Implant Systems
- Where
- 8 sites in France, Israel and 2 more
- Volunteers
- 100 people
- Sponsor
- Cochlear
Myelodysplastic Syndromes, Leukemia Myeloid Acute
A Study to Determine Final Geriatric Assessment in Haematology (GAH) Score as a Tool for Predicting Tolerance to Treatment in Elderly Patients (≥ 65 Years) With Haematologic Neoplasms
This is a post-authorization, retrospective multicentre observational nationwide study (PAS-OD). It will be conducted by reviewing medical records and database of patients who participated in the validation of the psychometric…
- Conditions
- Myelodysplastic Syndromes, Leukemia Myeloid Acute, Multiple Myeloma, Leukemia, Lymphocytic, Chronic, B-Cell
- Trial name
- NCT02842229
- Where
- 15 sites in Spain
- Volunteers
- 117 people
- Sponsor
- Celgene
Fatty Liver
Effects of Compound Probiotics-Polygonatum Sibiricum on Liver Health and Metabolism in Middle-aged and Elderly People
The purpose of this study was to evaluate the regulatory effects of Huangqian-biobacteria compound preparation on liver health and related metabolic disorders in middle-aged and elderly people, observe its effects on liver…
- Trial name
- NCT06873412
- Testing
- Probiotic, Placbo
- Volunteers
- 84 people
- Sponsor
- Wecare Probiotics Co., Ltd.
Infections, Rotavirus
Safety Study of GSK Biologicals' Rotavirus Vaccine (Rotarix®) Administered to Children Aged <1 Year in the United States
This observational cohort study, conducted through two existing large administrative health databases in the US (outside the Vaccine Safety Datalink) is planned to confirm the safety profile regarding lack of any association of…
- Trial name
- NCT00875641
- Testing
- Health Insurance Database
- Where
- United States
- Volunteers
- 390,659 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Malnutrition, Sarcopenia
Health and Nutrition Status of Chinese Elderly
This study is aiming to understand the prevalence and risk factors related to malnutrition and sarcopenia in Chinese elderly.
- Trial name
- NCT02089906
- Where
- 3 sites in China
- Volunteers
- 2,834 people, healthy volunteers welcome
- Sponsor
- Abbott Nutrition
Frail Elderly Syndrome, Older Adults
A Digital Home-Based Physiotherapy Program for Active Aging
This clinical trial will aim to understand the effects of the TRAK-SILVER digital platform on pre-frail and older adults living at home, assessing its impact on physical activity level, emotional variables, and overall quality of…
- Trial name
- TRAK-SILVER (NCT06381336)
- Testing
- TRAK-SILVER platform
- Where
- Spain
- Volunteers
- 72 people
- Sponsor
- Trak Health Solutions S.L.
Severe Hemophilia A, Moderate Hemophilia A
A Study to Evaluate Overall Health, Physical Activity, and Joint Outcomes in Participants With Severe or Moderate Hemophilia A Without Factor VIII Inhibitors on Emicizumab Prophylaxis
Study MO42623 is a Phase IV, multicenter, open-label, three cohort study designed to evaluate the impact of emicizumab prophylaxis on overall health, physical activity, and joint outcomes in participants aged ≥13 and <70 years…
- Trial name
- Beyond ABR (NCT05181618)
- Testing
- Emicizumab
- Where
- 26 sites in United States, Brazil and 10 more
- Volunteers
- 136 people
- Sponsor
- Hoffmann-La Roche
Safety: Healthy Subjects
A Study to Evaluate Safety and Health Benefits of Basis™ Among Elderly Subjects.
This study will investigate the safety, tolerability and potential health benefits of the dietary supplement, Basis. There will be two doses of Basis compared to a placebo.
- Trial name
- 15BSHE (NCT02678611)
- Testing
- Basis 250, Basis 500
- Where
- Canada
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Elysium Health
Malnutrition
The Nutritional Health for the Elderly Reference Centre Study (NHERC Study)
Elderly are at greater risk of dietary insufficiency due to age-related increases in nutrient requirements concomitant with a reduction in energy requirements, decreases in appetite and energy intake.
- Trial name
- NHERC (NCT03240952)
- Where
- 4 sites in Singapore
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Abbott Nutrition
COVID-19
Lot-to-lot Consistency of an Inactivated SARS-CoV-2 Vaccine for Prevention of COVID-19 in Healthy Adults
This study is a double-blind, randomized phase Ⅳ clinical trial of the inactivated SARS-CoV-2 vaccine (CoronaVac）manufactured by Sinovac Research \& Development Co., Ltd.
- Trial name
- NCT04894227
- Testing
- Inactivated SARS-CoV-2 Vaccine (Vero cell）
- Where
- China
- Volunteers
- 1,080 people, healthy volunteers welcome
- Sponsor
- Sinovac Research and Development Co., Ltd.